Research on the medical care of infants and children. Covers pediatric emergencies, blood-pressure thresholds, infectious disease, kidney injury, and developmental health.
New research suggests exposure to fathers' depression in pre-adolescence is associated with poor educational outcomes among males, but not females. Early identification and family-centered support can help promote school success and long-term well-being for affected sons.
A pilot study of 100 exclusively breastfeeding women found that maternal dairy intake is associated with decreased concentrations of numerous human milk lipids. The study suggests a link between healthy dairy intake and lower levels of specific milk lipid species, which may have implications for infant health.
A new study found that infants receiving maternal RSV vaccination or Nirsevimab after birth had significantly lower RSV infection rates and fewer severe complications. The study showed a high uptake of the vaccines among pregnant patients and newborns, leading to declining rates of RSV-related illnesses.
The study found that outpatient care for youth is driving the growth, with nicotine, cannabis, and opioids being the most common substances. Despite this, alcohol-related visits have declined in all care settings over the past 16 years.
A new study published at the Pediatric Academic Societies Meeting found that adolescents with high social media use had triple the odds of recent alcohol use compared to non-users. The study suggests that digital literacy and safe online navigation are crucial in reducing exposure to alcohol-related content.
Researchers estimate sepsis occurs in 1.3% of pediatric hospitalizations, resulting in a 10% mortality rate, and urges the need for immediate recognition and treatment. The study's findings highlight the importance of awareness among families to improve child survival rates.
Researchers are developing a new wearable technology to monitor babies' movements and detect early signs of autism. The study aims to improve early identification and intervention, which is crucial for optimal developmental outcomes in autistic individuals.
The number of pediatric lung transplants is expected to decline as highly effective therapies for cystic fibrosis reduce the need for transplantation. Complex cases with multi-system disease and severe cardiopulmonary compromise are on the rise, requiring highly specialized teams and close collaboration.
The Pediatric Academic Societies (PAS) recognizes 46 outstanding trainees and early career professionals for their contributions to pediatric research. The recipients will receive complimentary registration and a travel stipend to attend the PAS 2026 Meeting in Boston, Massachusetts.
Five fellows will receive funding for four years to study hard-to-treat pediatric cancers, reduce treatment toxicity, and develop innovative therapies. Their research focuses on Ewing sarcoma, leukemia, kidney cancer, and immune system vulnerabilities.
A recent study found that children from rural China are more prone to emotional issues, while urban children show more behavioral problems. These findings highlight the need for targeted interventions and underscore the impact of environment on mental health outcomes.
A national poll suggests that one in three parents report their young adult children are minimally active or inactive, with lack of interest and screen time being major barriers. Parents often try to encourage physical activity through verbal encouragement, activities, and exercising together, but many efforts are not successful.
A recent survey found that 72% of youth aged 13-17 use AI companions and 52% report regular use, highlighting the need for robust safeguards. Well-designed chatbots can normalize help-seeking, reduce isolation, and offer coping strategies, but poorly designed ones can cause harm.
A new study found that pediatric patients with long-COVID experience a high symptom burden, including sleep disturbance, anxiety, depression, and fatigue. The study describes an interdisciplinary care approach that incorporates integrative medicine, nutrition, and lifestyle modifications to manage symptoms.
Children's Hospital of Philadelphia (CHOP) researchers developed STRIPE, a targeted long-read RNA sequencing strategy, to reveal disease-causing genetic variants and provide molecular diagnoses for previously undiagnosed patients. The platform enables ultra-deep, full-length RNA sequencing at a practical scale, addressing the diagnosti...
Research from Alberta reveals that survivors of adolescent and young adult cancers are at double the risk of developing most types of later cancers. Lymphoma and breast cancer were found to be the most common subsequent cancers after an initial diagnosis, with breast, colorectal, and lung cancers making up 43% of cases.
A new study found that school-age children and adolescents with medically diagnosed traumatic brain injury (TBI) have higher rates of anxiety/depression. Family resilience was associated with decreased odds of depression after TBI, suggesting a crucial role in recovery.
A recent JAMA paper identifies key symptoms and signs that strongly indicate a child has sustained a concussion. Common symptoms include headache, dizziness, mental fog, nausea, sensitivity to light and noise, and difficulty remembering.
A study by researchers at the University of Gothenburg found that children born before 24 weeks of gestation incur significant societal costs, peaking in the first year of life. The need for support persists long after initial care, with severe complications often leading to more extensive and long-term support needs.
A study found that children who need dental care the most are less likely to participate in school-based cavity prevention programs, which can lead to significant savings for state Medicaid programs. Improving participation among high-risk children could save up to $2.4 million annually.
A new longitudinal study from Université de Montréal finds that three simple movement habits in toddlerhood significantly predict a more physically active lifestyle in adolescence. Active play with parents, limited screen time, and sufficient sleep are key predictors of later physical activity levels.
Researchers developed DARC-NESS, a model that explains why nightmares persist in children and how to break the cycle through tailored therapy. By focusing on nightmare efficacy and child response mechanisms, clinicians can create effective treatment plans to empower kids to master their dreams.
The American Society of Hematology and the International Society on Thrombosis and Haemostasis have released comprehensive guidelines for anticoagulant prophylaxis in non-cardiac pediatric patients at risk of venous thromboembolism. The guidelines outline best practices for preventing life-threatening complications in children.
A new study using a national database of e-scooter injuries found that children accounted for over 45% of e-scooter related injuries. Racial and ethnic disparities were also noted, with Black and Hispanic children seeing the highest rates of injury, at 16% and 15.7%, respectively.
The Alliance for Clinical Trials in Oncology is enrolling adolescent and young adult cancer patients in various trials, including genetic services and treatment studies. These trials aim to address longstanding gaps in care and improve outcomes for AYAs with cancer.
A simple, low-cost intervention empowers families who speak a language other than English to initiate interpretation services, increasing communication time with medical teams. The study found an average increase of 16 minutes per patient-day in interpreter use.
A team of researchers at North Carolina State University has created an injectable microgel called B-knob triggered microgels (BK-TriGs) that can help reduce bleeding in infants during surgery. The microgel works by mimicking the mechanical properties of natural platelets, which helps to create fibrin networks and stanch bleeding.
Researchers found that bleach and detergents were the most common product types associated with these injuries, accounting for over 33% of injuries. Children aged 1-2 years were at highest risk, and poisoning was the most common diagnosis, resulting from ingestion.
Children with rare food allergy FPIES exhibit atypical gut microbiota compared to healthy peers, according to a new Umeå University study. The analysis of stool samples revealed differences in bacterial composition associated with FPIES, which may contribute to the development of more individualized strategies for diagnosis and treatment.
A gene-edited treatment has shown remarkable success against severe sickle cell disease, with 27 out of 28 patients achieving a functional cure and no painful crises. The therapy uses CRISPR/Cas12a technology to modify stem cells and increase levels of fetal hemoglobin.
Researchers evaluated the performance of the Phoenix Sepsis Score for predicting in-hospital mortality among pediatric ICU patients in China. They found that a modified version, PSS+, showed substantially improved discrimination without sacrificing clinical usability.
Advanced AI models outperform clinicians in certain pediatric diagnostic tasks, especially for rare conditions. The study's findings suggest that AI can be a valuable tool when used alongside human expertise to improve diagnostic accuracy and reduce the risk of missed diagnoses.
A global clinical trial led by SickKids has found that mavacamten improves blood flow and reduces obstruction in youth with hypertrophic cardiomyopathy (HCM), a genetic heart disease. The study's results offer hope to families avoiding open-heart surgery, setting the stage for precision therapeutics.
Dr. Lisa G. Roth, MD has joined Hassenfeld Children’s Hospital at NYU Langone and Perlmutter Cancer Center as director of the Division of Pediatric Hematology-Oncology. She will oversee clinical care, research, and education programs while expanding access to advanced therapies and clinical trials.
A new set of evidence-based clinical guidelines has been developed to manage recurrent wheezing in infants and toddlers. The guidelines recommend standardized protocols for diagnosing and treating the condition, including laboratory tests and type 2 inflammatory disease testing.
The program aims to support future pediatric-focused professionals in dentistry, medicine and nursing through competitive scholarships and training. With the gift, UT Health San Antonio will expand access to high-quality care for children and families in Bexar County.
Researchers at USC will develop an AI-driven framework to strengthen evidence generation for gene and cell therapies, helping bring promising treatments closer to patients. The project aims to better understand how specific therapy features relate to patient outcomes.
A cohort study of 515 children found distinct cognitive-linguistic deficits in kindergarten associated with increased risk of early-emerging and late-emerging dyslexia. The findings support integrating developmentally sensitive screening into pediatric surveillance frameworks, enabling early identification and preventive care.
A new study found that ER triage scores for children's mental or behavioral health were inaccurate in two-thirds of cases, with biases against Black and Hispanic patients. Parents are advised to advocate for their child if they suspect a risk of self-harm or harm to others while waiting.
A recent study shows that a comprehensive TB screening and treatment program reduced TB incidence by 83% and prevalence of latent TB infection by 32% among Tibetan children in northern India. The program's success highlights the importance of community-led surveillance and treatment implementation to control TB transmission.
The study identified six sleep health dimensions in young adolescents: irregularity, timing, duration, social jetlag, weekend oversleep, and continuity. Greater irregularity was associated with higher concurrent transdiagnostic mental health symptoms, while shorter duration was linked to increased symptoms at follow-up.
Children with metabolically healthy obesity at treatment initiation have an increased risk of type 2 diabetes, hypertension, and dyslipidemia. Reduction in BMI z score is associated with reduced cardiometabolic risk, suggesting treatment should be recommended for these children as well.
A new study published in JAMA Pediatrics finds that children with obesity but without metabolic complications still face a significantly increased risk of developing type 2 diabetes, high blood pressure, and abnormal blood lipid levels later in life. Treatment can greatly benefit these children, reducing the risk of future diseases.
A new study estimates that more than 18,000 hospitalized children in the US have sepsis each year, including over 1,800 who die. The study also found that most pediatric sepsis cases were present on admission, but a smaller proportion developed during hospitalization and were associated with higher mortality.
A new study has estimated pediatric sepsis in the US, revealing a significant impact on pediatric hospitalizations. The study found that sepsis affects approximately 1.3% of hospitalizations, resulting in over 18,000 cases and more than 1,800 deaths annually.
A new automated tobacco treatment system integrated into pediatric care helped drive a significant increase in smoking cessation among mothers. The system showed improved behavior among mothers, potentially protecting hundreds of thousands of children from secondhand smoke exposure.
A national poll finds 1 in 3 parents worry their teen or young adult driver could cause an accident, with most witnessing unsafe driving behaviors. Despite concerns, most parents rate their child's driving as average or better, and relatively few impose consequences for risky behaviors.
A new trial found that infants and toddlers with unilateral cerebral palsy show significant improvements in hand and arm function when receiving early, high-dose therapy. The study suggests that multiple approaches can help children build critical motor skills, providing families and clinicians with evidence-based options.
A systematic review of 42 studies reveals a rising trend in self-injury among children and youth in high-income countries, with significant variability across countries. The findings highlight the need for effective, contextually informed prevention strategies to curb this growing concern.
A new study suggests that early life stress during pregnancy and early childhood can lead to long-term digestive issues, including gut pain and motility challenges. The research found that early life stress can shape the development of gut-brain communication, contributing to gastrointestinal symptoms in both mice and humans.
A new pediatric mental health care model, P2C3, combines primary care and psychiatry to improve access and training for future pediatricians. The model, which has completed over 1,500 visits and cared for over 400 patients, has shown durable and scalable results, reducing fragmentation and providing timely access to mental health care.
A 16-year study found that 87% of children with single-ventricle heart disease either died or developed a major health problem over time. The study provides new direction for improving care and offers guidance for tailoring therapies to each child.
A large E. coli outbreak in Calgary daycare centers resulted in 285 children becoming infected, with daily laboratory monitoring and treating dehydration preventing complications and potentially saving lives. The study found that this approach reduced the number of children who developed life-threatening hemolytic uremic syndrome.
A new biotech company, Ibnova Therapeutics, will accelerate treatments for heart disease through cellular therapies, backed by Australian and Danish partnerships. The company aims to conduct human clinical trials within three to five years.
A study in Taiwan found a positive association between maternal prenatal acetaminophen use and increased risk of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASDs) in offspring. However, associations were not observed in sibling-matched analyses, suggesting unaddressed sources of bias.
A systematic review and meta-analysis found consistent associations between digital media use and risks to child health and development, particularly social media use. The study highlights the need for multifaceted policies and interventions to mitigate potential harms from digital media exposure.
Researchers have demonstrated that stem cell treatment can be effective even when initiated after motor deficits appear in cerebral palsy. The study used stem cells from human primary tooth pulp to treat chronic-phase cerebral palsy in rat experiments, showing improved motor and learning functions in the treated group.
Children's Hospital of Philadelphia researchers highlight the need for parents and pediatricians to understand generative AI's potential benefits and risks for children of different ages. Early childhood (0-5 years) requires close supervision, while middle childhood (6-11 years) and adolescence (12+ years) require critical thinking ski...
Three UCF medical students presented their groundbreaking research on improving pediatric care for children with cleft palates and skull deformities. Their studies explored the use of robotic surgery, high-tech imaging, and new surgical approaches to enhance patient outcomes.
A Stanford Medicine-led study reveals that the US method for ranking children on heart transplant waitlists does not consistently prioritize the sickest patients. The current system fails to capture medical urgency, leading to higher waitlist mortality rates and potential unfair treatment of some patients.