Articles tagged with Pediatrics
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A new study reveals that infants, toddlers, and preschoolers can exhibit distinct long COVID symptoms, which may be challenging to identify due to their unfamiliarity. The study emphasizes the importance of pediatricians and family physicians considering long COVID in children presenting with similar symptoms.
A $1.1 million grant supports a natural history study for MCHS, collecting vital information about the condition to inform future clinical trials of therapies. The Volāre Study aims to provide baseline developmental trajectory information and establish infrastructure for multicenter clinical trials.
Research reveals that prenatal PFAS exposure can alter infants' developing immune systems, leading to lasting imprints on their ability to fight disease. Exposure to low levels of PFAS was associated with changes in key T-cell populations, including T follicular helper cells and regulatory T cells.
A new report reveals that one in five parents experience potty anxiety during toilet training, while another one in five finds the process harder than expected. Parents cite various reasons for starting potty training, including readiness signs, daycare or preschool requirements, and cost pressures.
ADLM 2025 will tackle urgent topics like clinical AI integration and fake medical news, as well as leveraging genomics for personalized healthcare. The meeting also explores the health threat of plastics and microbiome medicine to combat diseases.
The study found a significant increase in extremely severe obesity among US children and adolescents, leading to severe metabolic and cardiovascular complications. Extremely severe obesity was linked to conditions like metabolic dysfunction-associated steatotic liver disease, prediabetes or diabetes, and metabolic syndrome.
A systematic review found that optimal childhood heart health metrics, including diet, physical activity, and sleep, lead to lower risks of chronic diseases in adulthood. The review highlights the importance of early prevention and suggests that parents can focus on healthy habits and regular check-ups with pediatricians.
This study found that Black and Hispanic children were disproportionately hospitalized for COVID-19 and experienced severe disease compared to white and Asian or Pacific Islander children. Children with underlying medical conditions from these groups also had a higher proportion of hospitalizations.
A study published in Pediatrics reveals a sharp surge in nicotine pouch ingestions among young children, with a 763% increase in rate of reported cases between 2020 and 2023. The ingestion rates for other nicotine products declined during the same period.
A study by The Endocrine Society reveals that children with growth hormone deficiency experience improved overall health and coping mechanisms when their caregivers report reduced stress, anxiety, and depression. Conversely, caregivers' emotional stability is associated with better outcomes for the child.
Researchers developed a non-invasive questionnaire to identify children at risk of maltreatment, highlighting seven behavioral problem areas linked to maltreatment. The study found critical timing patterns and type of abuse matters, offering a more comprehensive approach to support maltreated children.
Recent studies reveal disparities in access to hepatitis C treatment for children and recently pregnant women, with significant racial and geographic disparities. The studies highlight the need for targeted resources to reach these vulnerable populations.
Research found that premature babies who had early skin-to-skin contact with their mother were more likely to be breastfed at discharge and for up to one year. Early contact also promotes bonding, reduces stress, and supports long-term development.
A study using AI language models analyzed sentiments and emotions expressed by almost 400 pediatric patients on social media, finding that 94% of comments were negative, with sadness and fear prevalent. The study highlights the need for integrated care approaches to support vulnerable young patients managing complex medical conditions.
A Northwestern University study finds disparities in peanut allergy prevention guidance, with low-income and minority parents less likely to receive accurate advice. Early peanut introduction cuts allergy risk by over 80%, but guidance is often inadequate for these families.
A new study predicts postoperative complications in children up to three days before formal diagnosis using wearable device data and novel metrics related to circadian rhythms. The results show 91% sensitivity and 74% specificity, indicating potential for facilitating faster treatment and care.
The Center will develop personalized CRISPR on-demand treatments for children with severe inborn errors of immunity and metabolic disease. The initiative aims to make CRISPR cures more affordable and accessible, building on recent clinical success in treating ultra-rare genetic diseases.
A new study by Children's Hospital of Philadelphia researchers found that US children's health is declining across multiple measurements. Chronic illnesses, physical and mental health conditions, and increased mortality rates were observed compared to other high-income nations.
Researchers developed an in-silico meta-analysis tool to determine optimal laser irradiation conditions for treating nevus of Ota. The study found that picosecond laser treatment demonstrated higher efficacy and equivalent safety compared to nanosecond laser treatment.
The study reveals that many people are unaware of two crucial facts that can help reduce SIDS deaths: putting babies on their backs to sleep, and avoiding secondhand smoke in the home. The survey found that only 65% know that a baby should be put to sleep on its back, highlighting a need for increased education and awareness.
The study found a statistically significant increase in hospital admissions due to pediatric clavicular fractures over the 10-year period, suggesting an increase in severity of those injuries. This calls for better injury prevention and management strategies for doctors, parents, and patients.
Researchers developed an innovative FENCY ligation technique combined with preoperative embolization to remove giant plexiform neurofibromas, reducing risk of complications and improving recovery time. The study results in significant functional improvement and high patient satisfaction rates.
A groundbreaking study has uncovered the unique architecture of cells and signals inside the joint as inflammation takes hold in children with arthritis. The research provides a new way forward for understanding this condition, which affects over 10,000 children in the UK.
A new software tool called VR-Omics has the potential to further our understanding of other childhood diseases. The technology can identify previously undetected cell activities of cardiac rhabdomyoma, a type of benign heart tumour that can cause respiratory distress and irregular heartbeat.
A recent study found that 85% of commercially insured deaf children with cochlear implants use spoken language, compared to 33% of Medicaid-eligible children. Family language was not a significant factor in spoken language development.
A scoping review highlights Europe's fragmented efforts in biliary atresia screening, calling for a unified approach that merges effective tools with innovation. The review assesses three major screening strategies: stool color cards, serum bilirubin testing, and biochemical profiling, emphasizing the potential of digital apps and AI-p...
The study found that the stage of normal cell development at which B cells transform into leukemic cells impacts treatment outcomes for pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL). Researchers identified a 'multipotency score' to predict clinical outcomes, providing valuable insights into drug resistance and str...
A Mount Sinai study found a post-pandemic increase in head and shoulder injuries among female and male youth hockey players, with higher rates of hospitalizations and fractures. The research highlights the importance of safer equipment standards, injury prevention strategies, and education to protect young athletes.
A new UVA Health study finds that stocking two twin packs of epinephrine autoinjectors and having campers leave their own at home is the most cost-effective strategy for residential camps. This approach comes with an estimated overall cost of $4.33 per camper.
This study found that increased screen time in late childhood was associated with more depressive symptoms, likely due to shorter sleep duration. Poor white matter organization during early adolescence may also contribute to this link.
Researchers at St. Jude Children's Research Hospital have identified a novel combination therapy approach to treat pediatric acute myeloid leukemia (AML) fueled by NUP98 fusions. Targeting the complex alone or in combination with another anticancer drug significantly increased survival in AML model systems.
JMIR Publications' portfolio of journals now includes 21 titles with a Journal Impact Factor. Several journals saw significant increases in impact factor, including JMIR Medical Education, which debuted with a score of 12.5, securing the top-ranked journal spot in its category.
The Supreme Court's decision increases the likelihood of states limiting or eliminating family access to medical care. Medical professionals emphasize the need for individualized assessments and patient-centered care.
A study published in the American Journal of Human Genetics identified a novel gene, BSN, linked to neurodevelopmental disorders and epilepsy. The research used large biorepositories and computational techniques to analyze data from patients with variants of the BSN gene. Key findings include the common symptoms of epilepsy, febrile se...
Children's Hospital of Philadelphia researchers found that rare instances of SYNGAP1-related disorders can be caused by inherited genetic variants, which could help guide clinical care and influence family planning decisions. The study identified eight individuals with inherited protein-truncating variants in the SYNGAP1 gene.
The Princess Máxima Center has implemented whole genome sequencing as the standard of care for children with cancer, enabling precise diagnosis and tailored treatment. This comprehensive approach also provides valuable data for developing new treatments and researching childhood cancer development.
A study identified distinct trajectories of addictive social media, mobile phone, and video game use in US youths, finding links to increased suicidal ideation and worse mental health outcomes. The research suggests that high or increasing addictive screen use may warrant further clinical evaluation and intervention design.
A survey of 261 new fathers found that 64% took less than two weeks of leave, while 36% took more than two weeks. The main barrier was fear of losing their job. Paid leave would reduce barriers and increase take-up. Involving dads in childcare from the start is crucial for healthy outcomes.
A cohort study suggests severe neonatal morbidity is a significant risk factor for childhood mortality, highlighting the importance of preventing and identifying early signs of severe conditions. Efforts to reduce mortality through infancy and late adolescence may benefit from targeted prevention strategies.
A new study from Karolinska Institutet found that infants who survive serious health problems in the first few weeks of life have a higher risk of dying during childhood and adolescence. Children with neurological health problems had almost six times the risk of death compared to healthy children.
Researchers discovered that children with MS show signs of accelerated biological aging, even in their teenage years, which may lead to new treatment possibilities beyond immunosuppression. The study found that youth with MS had evidence of accelerated epigenetic age, a measurement of DNA chemical modifications associated with aging.
A new study reveals that states with permissive firearm laws have significantly higher rates of pediatric mortality due to gun accidents. The research highlights the need for stricter regulations to prevent such tragedies and determine which laws are most effective in reducing harm.
A NYU College of Dentistry study found that topical treatments for kids' cavities can significantly prevent decay from worsening. The use of atraumatic restorations (ART) and silver diamine fluoride (SDF) in schools kept 62% and 55% of decayed surfaces under control, respectively.
A Kennedy Krieger researcher's work on a promising oral drug, leriglitazone, has shown it can slow the progression of cerebral adrenoleukodystrophy (cALD) in all 11 trial participants. Nearly half of boys treated with the medication appeared to halt disease progression entirely.
Researchers found that childhood kidney cancers have significantly more genetic changes than previously thought, with some tumors having up to millions of changes. This discovery challenges the existing notion that childhood cancers have few genetic variants and suggests new treatment options such as immunotherapy.
A computerized decision support tool reduced the time children with lung failure spent on ventilation by shortening weaning time and improving respiratory muscle strength. The intervention group had better functional status at ICU discharge than the control group.
Researchers identified unique symptom patterns and derived research indices for infants/toddlers and preschool-aged children, highlighting the need to characterize long COVID separately across age groups. The study provides new insights into the condition's progression in early childhood.
Approximately one in three pediatric mental health ED visits resulted in prolonged stays exceeding 12 hours, with over half due to suicidal thoughts or aggressive behaviors. The study highlights significant issues with access to mental health care for children and adolescents.
The new guidelines aim to improve health outcomes by providing evidence-based recommendations for managing VTE in children. Direct oral anticoagulants are now recommended as a first-line treatment option in many cases.
Researchers at Dana-Farber Cancer Institute and Broad Institute of MIT and Harvard uncovered critical insights into the biology of embryonal tumor with multilayered rosettes (ETMR), a rare and aggressive brain tumor affecting young children. Targeting FGFR and NOTCH receptors may represent a critical vulnerability in ETMR.
A new study published in JAMA Network Open found that as preteens used more social media, their depressive symptoms increased by 35%. The research team tracked changes over time in each child to accurately assess the link between social media and depression. Experts suggest using digital habits tools to create healthier online behavior...
A retrospective study found that allogeneic hematopoietic stem cell transplant is a highly effective method for treating children with monogenic inflammatory bowel disease, resulting in sustained medication-free remission in over 90% of patients. The treatment also led to significant improvements in growth, reduced hospital visits, and...
A large study found an unexpectedly high frequency of pulmonary embolism in pediatric patients, equal to rates seen in adults. The study provides new criteria for clinicians to diagnose PE in children and raises questions about the need for earlier intervention.
Charles G. Mullighan, a leading leukemia researcher at St. Jude Children's Research Hospital, has been elected Fellow of the Royal Society. His work on genomic research has advanced the understanding and treatment of acute leukemia in children.
A new survey reveals that parents are just as concerned about their child's mental health during the summer as they are during the school year. The top worries include excessive screen time, boredom, and disrupted routines, with one in 10 parents being more concerned.
A new study reveals that synthetic opioid-involved fatal overdoses among youth aged 15-24 in the US were predominantly caused by fentanyl alone. The rates of overdose deaths involving only fentanyl increased significantly across age, sex, and race/ethnicity, with the highest rates found among males and young adults.
A recent study published in PLOS ONE found that higher maternal selenium levels during pregnancy are associated with a lower risk of streptococcal infections in children. The research tracked over 74,000 mothers and their children to explore potential links between maternal metal exposure and infection risk.
Experts recommend stopping pacifier use and thumb-sucking before two years old due to potential dental health and speech development impacts. Parents report various strategies to break the habits, including hiding the pacifier, limiting use, or using deterrents like hot sauce.
A new study found that ciliary dynamics play a significant role in the pathophysiology of bronchopulmonary dysplasia, with more severe cases showing distinct ciliary beat abnormalities. The study provides new insights into BPD mechanisms and potential therapeutic targets.
A recent survey found that over 83% of Americans believe the benefits of the MMR vaccine for children outweigh the risks, despite a current measles outbreak. The survey also showed that vaccination rates are dropping and many people lack knowledge about measles symptoms and prevention.