Articles tagged with Pediatrics
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The American Academy of Pediatrics 2025 National Conference & Exhibition will focus on pediatric care, early childhood development, and digital media. Key sessions include discussions on fad diets, social media influence, and mental health in adolescence.
A recent study found that young people are increasingly turning to sodium nitrite and nitrate as a method of suicide after buying the products online. The chemicals, which can cause hypoxia and eventual death when ingested, are often readily available for purchase online.
A significant risk factor for in-home firearm homicide is domestic violence and child abuse, highlighting the need for improved safe storage laws and extreme risk protection orders. Young children are disproportionately affected, emphasizing the importance of preventing these deaths through stricter regulations.
Research suggests that exposure to dog allergens in the home may reduce the risk of developing childhood asthma by five years old. Babies with higher levels of Can f1, a dog skin protein, had around a 48% lower risk of developing asthma and better lung function.
New research reveals that zebrafish models can help guide clinical decision-making in real-time for challenging pediatric cancer cases. The study shows that pre-clinical zebrafish models accurately predicted responses to 11 of 12 treatment regimens, providing robust and actionable treatment response data.
Researchers developed MCA to address technical difficulties in esophageal atresia repairs; the technique involves prior approximation of esophageal ends followed by endoscopic delivery of magnets for anastomosis creation. Optimal compression force, surface coating, and tissue preparation are critical factors for successful implementation.
The data release from the HEALthy Brain and Child Development Study offers a detailed look at human brain development in early childhood. The comprehensive data includes information on prenatal health, social and environmental determinants of health, and wearable biosensor data.
A recent study found a small-but-significant link between exposure to radiation from medical imaging and blood cancers in children and adolescents. The study concludes that while ionizing radiation is a carcinogen, the benefit-to-risk ratio favors CT imaging of children when justified and technique minimizes adverse effects.
A study of 1,620 participants aged 6-80 found that motor skills develop rapidly in children up to age 10, with adults reaching peak performance between 20-35 years old. Fine motor skills remain stable into old age, while gross motor and strength decline faster with age.
A review of hundreds of studies found a link between childhood plastic exposure and long-term health concerns like heart disease, obesity, and asthma. Parents can take simple steps to limit their children's plastic exposure, such as replacing plastic containers with glass or stainless steel.
The American Academy of Pediatrics will host its 2025 National Conference & Exhibition in Denver from September 26 to 30, featuring educational sessions, seminars, and a exhibit hall. The conference will address various topics such as AI in pediatric practices, social media's impact on children, and mental health.
Researchers at Children's Hospital of Philadelphia developed a quality improvement initiative to increase dental varnish application rates. The effort resulted in a significant boost in varnish use, with over 50% of children receiving varnish annually, exceeding the target goal of 20%.
A study published in The New England Journal of Medicine found that nearly 4 million children and adolescents were at higher risk of developing blood cancers due to radiation exposure from medical imaging. The researchers estimated that up to 10% of pediatric blood and bone marrow cancers may be attributable to radiation exposure.
A new study published in Autism found that autistic children are more likely to experience ongoing gastrointestinal problems than their typically developing peers. These symptoms can affect sleep, communication, sensory processing and behavior, and often don't have an identified medical cause.
New research suggests that integrating behavioral health services in pediatric primary care can lead to improved mental health outcomes for children and adolescents. The study, published in JAMA Network Open, found that children who received integrated behavioral health care reported fewer behavioral health symptoms over time.
Researchers found a significant drop in rescue breathing cardiopulmonary resuscitation (CPR) for children, leading to increased death rates and worse outcomes. The study estimated that the decline may have caused about 10.7 more pediatric deaths each year during the pandemic.
A growing body of research links environmental pollutants to worsened health and shorter life spans in childhood cancer survivors. The study found that only 25% of pediatric oncology providers felt comfortable discussing environmental pollutant impacts with patients.
This cohort study found that receiving encounters with behavioral health clinicians and psychotropic prescriptions was associated with reduced psychosocial symptoms. The results suggest that expanding integrated pediatric behavioral health care could improve outcomes among vulnerable child populations.
A new national poll reveals that parents of children with health conditions are less confident about their child's ability to have a positive school year. The poll found that these parents are more likely to be concerned about their child adjusting to a new school or teacher, dealing with conflict, staying healthy, and fitting in.
A new study highlights why kids' brain tumors need therapies designed for their unique biology, pointing to engineered immune cells and cancer vaccines as promising approaches. The review emphasizes the need for targeted treatments that recognize and fight childhood brain tumor differences.
A systematic review and meta-analysis of 18 trials found GLP-1 RAs significantly improved glycemic and weight outcomes in children and adolescents with type 2 diabetes or obesity. However, gastrointestinal adverse effects warrant attention in long-term management.
Children with variable levels of walking impairment experience significant physical activity, social engagement, and family life improvements. Parents also report increased confidence, self-belief, and reduced anxiety in their children.
Researchers from Mass General Brigham developed a bespoke CRISPR-Cas9 gene-editing enzyme to correct the genetic error causing multisystemic smooth muscle dysfunction syndrome, a rare condition associated with stroke and death in childhood. The therapy extended survival four-fold in mouse models of MSMDS.
A retrospective cohort study found that children of racial and ethnic minority groups receiving CPR had higher odds of in-hospital mortality. Additionally, the odds of in-hospital mortality among children receiving CPR were higher at hospitals with the highest proportion of Black patients.
A new clinical trial found no significant neurodevelopmental effects on infants and young children after brief inhaled anesthesia and surgery. The study used a balanced strategy with lower doses of sevoflurane and did not show meaningful short-term differences in IQ or child behavior problems.
A recent study provides insights into the true impact of chikungunya on pediatric health, revealing diagnostic challenges and limited public health responses. Infants are especially susceptible to severe complications, emphasizing the need for improved research, diagnostics, surveillance, and policy.
A federally funded study found children with leukemia who were exposed to pesticides during their mother's pregnancy had a higher risk of death. The study, published in Cancers, examined over 800 children and showed pesticide exposure increased child mortality by up to 60%.
A comprehensive registry study in Sweden found that healthy, full-term babies under three months old are at risk of severe illness from RSV. The study highlights several risk factors, including birth weight and sibling age, which increase the risk of needing intensive care or dying.
Children undergoing cancer treatment often lose skeletal muscle at a time when they should be rapidly gaining it, which can increase treatment complications and raise the risk of long-term health problems. Muscle loss makes children more vulnerable to heart and metabolic issues like high blood sugar and insulin resistance.
Integrating automated smoking cessation interventions into pediatric primary care significantly increased treatment received and reduced cigarettes smoked among parents. The study found that the interventions led to a greater reduction in cigarette use, improved quit rates, and increased health navigator support.
The Gabriella Miller Kids First Pediatric Research Program has released its 36th study, introducing significant new data updates to two existing studies. These advances aim to uncover the genetic foundations of childhood cancers and congenital conditions. With over 110,000 data files available, researchers can explore publicly accessib...
A new study found that the end of COVID-era federal funding led to a significant increase in uninsured children visiting emergency departments in Texas, with 45.2% more visits than before. The share of commercially insured patients also rose 12.5%, while Medicaid-insured visits declined by 11.7%.
A new study from Memorial Sloan Kettering Cancer Center shows the Make-an-IMPACT program improves global access to genomic testing for pediatric cancer patients. The program helps develop an experimental antibody that shows promise against metastatic cancer. Researchers also shed light on the origins of ERG-driven prostate cancer and f...
A new study found that fewer than half of children with sickle cell disease and Medicaid in Michigan received dental services. Dental health is crucial for these children due to the reciprocal relationship between the disease and oral infections.
A study by Professor Chunxiu Gong's team identified the clinical presentation of Cornelia de Lange syndrome (CdLS) and genetic alterations in Chinese pediatric patients. The researchers found that 12 patients presented with classic CdLS, while others showed global developmental delays and growth retardation.
Researchers found neglected children had abnormalities in critical brain regions, including right corticospinal tract and superior longitudinal fasciculus, linked to behavioral difficulties. These findings provide objective markers for identifying children affected by neglect.
A Stanford Medicine-led study found that many young children with ADHD are prescribed medication just after diagnosis, contradicting treatment guidelines. The study highlights a gap in medical care for 4- and 5-year-olds with ADHD, who should try six months of behavior therapy before starting medication.
Researchers discovered that GLP-2 analogs reshape the intestinal environment by expanding villi and crypts, increasing regulatory T cells, and improving nutrient absorption. This breakthrough offers new hope for patients with short bowel syndrome and potentially benefits immunocompromised individuals.
Researchers at Children's Hospital of Philadelphia found that certain lipids in obesity-causing foods cause asthma-like lung inflammation. The study suggests that modifying dietary choices and repurposing existing drugs could help treat this type of asthma, which is more likely to send patients to the hospital.
According to UMass Amherst research, only 16% of US counties offer access to vaginal labor after C-section. Despite the American College of Obstetricians and Gynecologists' guidelines supporting this option, access remains limited due to factors such as hospital availability and provider comfort.
Children living in low-opportunity neighborhoods are more than 20 times likely to be hospitalized for gun injuries compared to those in high-opportunity areas. Unintentional shootings account for the majority of these cases.
A recent study found that large portions of obesity-related conditions in US adolescents and young adults are attributable to obesity. Treating and preventing obesity may reduce these conditions and associated costs. The researchers emphasize the importance of addressing childhood obesity to prevent future health issues.
A study suggests that children's depression may contribute to worsening maternal depression, rather than the other way around. This finding highlights the need for family-centered approaches to mental health care.
The study found a significant reduction in mortality while waiting for a new heart, despite increased waiting times. Technological advances and improved healthcare practices are credited with the improvements.
Researchers from the University of Pennsylvania School of Veterinary Medicine and Children's Hospital of Philadelphia discovered a link between mitochondrial dysfunction in the blood-brain barrier and neuropsychiatric disease in patients with 22qDS. Treatment with bezafibrate, a cholesterol drug, may enhance BBB function and correct so...
A three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency, a rare inherited neurological disorder. The treatment, Kebilidi, is expected to take 2-6 months to show measurable impact and has already shown signs of increased energy and happiness.
The Society for Cardiovascular Angiography & Interventions (SCAI) has published a new position statement providing best-practice guidance for the treatment of patent ductus arteriosus (PDA) in premature infants using transcatheter occlusion. The guidance emphasizes patient selection, pre-procedural planning, and post-procedure follow-u...
Pediatric orthopedic surgeons at Ochsner Children's perform the first robotic-assisted pediatric spine deformity surgery in Louisiana using Globus Medical's ExcelsiusGPS technology. The procedure enables unprecedented surgical precision and accuracy, improving patient outcomes.
Pediatric high-grade glioma tumors have unique genetic patterns that can be targeted by immunotherapy. Researchers identified a specific protein structure, NRCAM, that is essential for cancer cell migration and invasion, making it an attractive target for new treatments.
A prospective study found that better control of inflammation during childhood leads to less stiffening of the esophagus and fewer disease complications. The study suggests that stiffness of blood vessels in the esophagus could be an important biomarker for disease progression, indicating which patients may benefit from current therapies.
A pediatric investigation study reveals that male fetuses prioritize growth while female fetuses focus on placental development under gestational hypertension. The findings support the growth strategy hypothesis and suggest sex-specific differences in fetal responses to prenatal stressors.
A new national survey finds that nearly a third of parents (30%) report their child missed more than a week of school due to fear or anxiety. The Kids Mental Health Foundation offers free resources to help parents and caregivers understand and manage school avoidance.
Key findings show a decline in childhood and adolescent immunization rates in Michigan, with completion rates dropping sharply during the COVID-19 pandemic. The study highlights the need for targeted efforts to increase immunization rates in counties with lower income and higher uninsurance rates.
A new precision genomics initiative is launching to improve pediatric cancer diagnostics and research. The BrightSeq platform aims to deliver actionable genomic findings to care teams while accelerating research through robust sample acquisition.
St. Jude receives its third consecutive Magnet designation and first Magnet Designation with Distinction, recognizing its commitment to exceptional nursing care and patient outcomes. The hospital's nursing programs, including the Nurse Residency Program and Center of Advanced Practice, have contributed to its success.
Researchers conducted a randomized clinical trial to compare low- and high-dose methylprednisolone with azithromycin for treating severe Mycoplasma pneumoniae pneumonia. The study found that lower dose regimen of glucocorticoids is sufficient, equally effective, and safer than the high dose regimen.
A new study by Children's Hospital of Philadelphia researchers has found that eye-tracking metrics can help identify concussion-related vision disorders in patients with persisting post-concussive symptoms. The study used an objective infrared eye tracking device to measure gaze positions and found a significant correlation between the...
A Stanford Medicine-led report found that children with rare flu complications like influenza-associated acute necrotizing encephalopathy (ANE) need prompt treatment to survive. The condition causes brain swelling and a runaway immune response, leading to fatal outcomes if left untreated.
A European study analyzed data from over 30,000 children with brain tumors, providing a clear overview of their survival outcomes. The study found that differences in survival rates between countries are smaller than previously thought, suggesting improved access to similar treatments across Europe.
A combination of technological interventions is required to prevent children from dying in overheated cars, according to a new study. The researchers identified exemplar scenarios that led to pediatric vehicular heatstroke and found that no single technology can prevent all cases.