Articles tagged with Animal Cells
Scientists discovered a new way cells fight infection, using a method called antibody-directed xenophagy (ADX), which can digest bacteria and viruses inside infected cells. ADX is triggered by a protein called TRIM21, which flags invading pathogens for destruction.
Researchers at the Max Planck Institute for Brain Research discovered that stressed animal cells, including neurons, assemble inactive ribosomes into tightly linked pairs, known as disomes. This novel mechanism relies on a specific piece of ribosomal RNA called an expansion segment to form a precise RNA-RNA interaction.
Alec Whited's published study reveals a previously unknown cellular pathway that enhances waste removal, potentially treating autoimmune diseases and improving wound healing. The research, coauthored with a UTA doctoral student, was recently published in Genetics, a prestigious journal.
AcCELLerate has partnered with ATCC to provide customized Master, Working, and assay-ready instaCELL banks for research clients. Researchers will gain access to high-quality, authenticated cell lines with increased assay reproducibility.
Researchers Prof David Julian McClements and Prof David L. Kaplan propose hybrid foods as a solution to reduce industrial animal use's carbon footprint and boost health. The authors emphasize the need for collaboration to optimize protein combinations balancing nutrition, taste, sustainability, and affordability.
Researchers reveal how hybrid foods combining proteins from different sources could be part of the solution to reduce industrial animal use. By using combinations of different proteins, they found that hybrids can overcome many limitations of individual protein sources and create products that are more than the sum of their parts.
A high protein diet has been shown to improve birds' immune function and tolerance to infection by triggering the expression of immune-related genes. Birds fed a high protein diet were more resistant to infection and showed reduced symptoms compared to those fed a high lipid diet.
Researchers from Anglia Ruskin University and Imperial College London used advanced paleoproteomic techniques to analyze dinosaur fossils, discovering red blood cell-like structures in a fossil. This finding raises the possibility that soft tissue and cellular components are more commonly preserved in ancient remains than previously th...
Estrogen-related receptors play a crucial role in regulating muscle cell metabolism and energy production. Researchers discovered that these receptors can increase mitochondrial numbers and enhance energetic output when muscles need more energy, making them a promising therapeutic target for metabolic disorders.
Scientists have successfully integrated chloroplasts from algae into hamster cells, allowing the cells to undergo photosynthesis and producing oxygen and energy. This breakthrough could lead to the development of artificial tissues that can grow in size without limitations due to low oxygen levels, paving the way for innovative biotech...
Researchers developed a high-speed modulation system combining digital display with super-resolution imaging, significantly improving lateral and axial resolution. This enables detailed study of subcellular structures in animal cells and plant ultrastructures, paving the way for future biological discoveries.
A research team studied developing lamprey embryos to clarify the evolutionary origin of the vertebrate skull, finding that the head mesoderm diverged early in evolution. The study challenged long-standing debates on the development and origin of somites, providing new insights into the age-old question.
Researchers at Göttingen and Warwick Universities studied the structure and mechanics of cytoskeletal networks composed of actin isoforms. The study found that gamma actin forms rigid networks near the cell apex, while beta actin preferentially forms parallel bundles with distinct organizational patterns.
Coral cells use a molecule called LePin to mark friendly algae for ingestion, a mutually beneficial relationship that helps corals survive. This discovery could inform strategies to prevent coral bleaching and promote coral resilience.
Researchers at Salk Institute discover that dysfunctional mitochondria at synapses fail to meet energetic demand, supplying either too much or too little power and potentially causing working memory impairment with age. Adherence to the ultrastructural size principle is essential for avoiding cognitive decline in aging brains.
Researchers at NUS have developed a method to produce cell-based meat using magnetic pulses, reducing reliance on animal products and increasing efficiency. This technology has the potential to revolutionize the food industry and improve regenerative medicine by stimulating the growth of healthy cells.
Scientists have successfully delivered a common blood pressure medication directly to the inner membrane of mitochondria, targeting energy-producing parts of cells. The new method uses the body's natural transport system to deliver drugs more precisely, potentially improving therapy efficacy and reducing negative side effects.
Researchers have identified proteins that form gel-like filaments to protect cells from mechanical stress during dehydration. These findings could lead to improvements in preserving cell materials and biomolecules in a dry state.
Amy Rowat's research on cultured meat has made significant progress, with a new study showing the potential for efficient production methods. By using gelatin and food-grade enzymes to create edible microcarriers, Rowat's team is paving the way for lab-grown meat alternatives.
A new study challenges a popular scenario explaining the origin of eukaryotes, suggesting that cells can grow to considerable volume without acquiring mitochondria. Researchers explore energy requirements and genome arrangement in prokaryotes and eukaryotes, revealing overlap between cell types rather than a hard boundary line.
Researchers developed a mathematical model to predict the efficiency of nanoparticle delivery into cells, particularly in stem cells. They found that nanoparticles become trapped in bubble-like vesicles, preventing them from reaching their targets.
In a new study, researchers found that microglia cells are responsible for neuronal death in a mitochondrial disease mouse model. Suppressing these cells with the drug Pexidartinib increased life expectancy and reduced motor problems. Further research is needed to understand the specific process by which microglia attack neurons.
Researchers at Nagoya University discovered a tubulin homolog protein in the archaeon Odinarchaeota, which forms microtubules critical to cell organization. The study reveals an intermediate structure between bacterial and eukaryotic cells, shedding light on the evolution of complex cellular features.
A UC Riverside genetic discovery found that mosquitoes lack the primary ecdysone transporter, allowing researchers to develop a mosquito-specific insecticide. This breakthrough could help control Zika, dengue, and other virus-carrying mosquitoes without harming beneficial insects.
Researchers found that jellyfish's stinging cells evolved by repurposing a neuron inherited from a pre-cnidarian ancestor. This discovery provides insights into the emergence of new cell types and the evolution of biodiversity, suggesting that co-option of ancestral cell types was an important source for new cell functions.
Researchers discovered that moss cells can form mobile spindles during mitosis, moving like animal cells. This unusual process suggests a tug-of-war between microtubules and actin filaments to position the spindle, similar to animal cells.
A new study by University of California, Riverside researchers has found that coral-algal symbiosis can initiate without photosynthesis. This breakthrough could help corals survive climate change and ultimately save coral reefs.
A study by Kyoto University reveals that crickets' wings form from the lateral tergum of their wingless ancestors. The researchers used gene knockouts and microsurgery to identify key cell types involved in wing formation.
Scientists have discovered a yeast self-destruct pathway, adding to evidence that unicellular organisms have programmed cell-death mechanisms. This finding could lead to new antifungal drugs targeting such mechanisms.
A preclinical study suggests that SARS-CoV-2 infection can cause ferroptosis in pacemaker cells, leading to cardiac arrhythmias. Researchers used animal models and human stem cell-derived pacemaker cells to demonstrate the virus's impact on these cells.
Scientists developed a natural antibacterial texture inspired by insect wings, killing up to 70% of bacteria. The innovation aims to reduce food waste, particularly in meat and dairy exports, and extend the shelf life of packaged food.
Researchers found that mosquitoes' odor sensors shut down when forced to produce odor-related proteins, ignoring common insect repellents. This 'expression' process allows mosquitoes to adapt to their surroundings and avoids human scents.
Researchers discovered that juvenile birds rely heavily on their in-built compass during the first migratory flight, bypassing easier coastal routes. The brain's head direction cells exhibit a preference for the north orientation, even when faced with unfamiliar environments, suggesting an innate ability to navigate.
Dartmouth researchers identified a new type of neuron in the rat brain that facilitates visual and spatial processing by tracking visual landmarks. The postrhinal cortex neurons can fire in two directions depending on the environment, allowing rats to estimate their direction.
Researchers analyzed the largest cross-species database to assess species-specific cancer mortality rates and found conclusive proof that cancer risk is largely independent of body mass and life expectancy. The study highlights potent mechanisms of cancer resistance in larger species, contradicting intuitive expectations.
A team of scientists led by Vimal Selvaraj has developed a way to preserve the genetic diversity of fast-disappearing native cattle breeds using stem cells. This technology could be used to clone extinct breeds or to produce animals with desirable traits, such as disease resistance and extreme weather tolerance.
Researchers have identified the specific genetic regulatory elements responsible for Hydra head regeneration, showing that dynamic chromatin remodeling and transcription factor motifs play a crucial role. This discovery sheds light on the complex developmental processes involved in this remarkable regenerative ability.
Researchers have pushed the limit of when water will freeze to -44 C by using soft interfaces like gels or lipids. This discovery has significant implications for climate prediction, cloud conditions, cryopreservation of organs, and technologies exposed to icing conditions.
Researchers at MIT observed the intricate choreography of butterfly scales forming during metamorphosis, revealing a shingle-like pattern and nanometer-high ridges. The findings could inform the design of new materials like iridescent windows and waterproof textiles.
A groundbreaking technique allows researchers to study the unique venom production of a wide range of venomous animals, including scorpions, fish, and the platypus. This non-lethal approach provides new insights into how animals produce venom and opens up possibilities for discovering new drugs.
Researchers use transgenic worms to study whole-body regeneration and identify critical genes involved. They also gain insights into muscle cell connections and communication during regeneration.
A team led by David Kaplan at Tufts University aims to produce an alternative food source using cell-grown meat, driving efforts to enhance food sustainability and nutrition. The five-year project will combine interdisciplinary teams to evaluate consumer acceptance, environmental impact, and economic viability.
Researchers discovered that cytoquakes, rapid rearrangements of the cytoskeleton, occur due to slow buildup and sudden release of mechanical energy. These disturbances may aid cells in responding quickly to signals from their environment.
Researchers used machine learning to discover that sperm with a wide head relative to length are more likely to clump together and swim collectively, a rare behavior that sometimes helps them reach an egg faster. The study provides a new method for understanding how form and function are related in cells with complex behaviors.
A new study assesses the potential trajectories of cellular agriculture, a technology that grows cultured meat, dairy, and egg products from animal cells and yeast. The research highlights the need for increased public investments in open-source research and education to ensure a just and equitable development of the sector.
Researchers analyzed over 19,000 comb cells built by 12 colonies and found that worker bees adapt their building behavior to overcome various challenges, such as merging unaligned cells. The study suggests that honeybees are skilled architects rather than automatons, capable of solving complex problems through creative solutions.
Researchers at Heidelberg University successfully introduced a rare genetic mutation into a fish model to study the causes of complex metabolic diseases. The study found that supplying fully functional ALG2 mRNA could reverse the genetic defect, allowing analysis of individual function areas of the enzyme.
Scientists have developed a Japanese rice fish model to study congenital disorders of glycosylation, including ALG2-CDG. The model replicates symptoms such as neuronal problems and retinitis pigmentosa, and demonstrates that supplying fully-functional Alg2 can prevent defects.
Scientists at Johns Hopkins Medicine counted brain cells in fruit flies and three mosquito species, revealing an average of 200,000 neurons. This estimate likely represents a baseline number of brain cells required for complex behaviors. The study provides insight into the intricate processing capabilities of these insects.
Researchers at UC San Diego have developed a novel genetic sensor called CopyCatcher to detect precise CRISPR editing in cells throughout the body. The study shows promise for treating genetic disorders such as blood diseases, vision and hearing problems, and muscular dystrophy.
A team of researchers has developed a computational framework that captures cell interactions and their impact on embryonic tissue dynamics. They found that dynamic forces and tension fluctuations are responsible for the fluid state of tissues during development.
Researchers have discovered fossilized samples of bony armor from ancient fish species, revealing a complex network of cavities and channels in the bones. The findings suggest that early vertebrates had internal structures similar to those found in modern vertebrates, with bone cells capable of dissolving and restoring bone minerals.
Researchers use zebrafish to study human cancer and discover that the innate immune system actively destroys cancer cells. However, tumor cells can adapt and evade immune detection through a process called 'Immunoediting', leading to immunotherapy resistance.
UMass Amherst researchers discovered that the actin networks of a deadly fungus, Batrachochytrium dendrobatidis (Bd), play crucial roles in its pathogenicity. The study provides insights into the evolution of actin cytoskeleton and sheds light on the disease chytridiomycosis affecting amphibian populations.
Researchers found that plants use rapid oscillations of stems and leaves due to wind to activate molecular switches, allowing them to respond to environmental changes. This discovery highlights the importance of plant sensitivity to mechanical signals, enabling them to prepare for storms.
Researchers have discovered rare decision-making genes that control cell responses, potentially helping to prevent diseases such as heart attacks and organ failure. This new knowledge can also be applied to understand how aquatic animals respond to global warming and improve human health, agriculture, ecology, and marine biology.
Researchers engineered a SARS-CoV-2 variant with the D614G substitution to compare its characteristics against the ancestral form in human cells and animal models. The results suggest that the variant does not significantly enhance pathogenicity but may increase transmissibility.
Researchers have characterized a new population of T cells called ThGM cells that produce GM-CSF, contributing to autoimmune response in MS. The study found that ThGM cells induce inflammation in the brain and spinal cord, suggesting their role in autoimmunity.
A 429-million-year-old trilobite fossil's internal structure reveals similarities with modern bee eyes and compound eyes of crustaceans. The findings suggest that vision principles in these insects have remained largely unchanged since the Palaeozoic era.
Quat-containing disinfectants have raised concerns over potential toxicity, with links to fertility and developmental problems found in animal and cell experiments. However, industry experts argue that skin irritation is the biggest concern, and typical exposures in people are unlikely to pose significant health risks.