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Treating autism by targeting the gut

Researchers found that restoring a healthy balance in gut bacteria can treat Autism Spectrum Disorder (ASD) symptoms. The review highlights several studies showing positive impacts of probiotics, prebiotics, diet changes and faecal matter transplants on ASD symptoms.

SourceFrontiers·JournalFrontiers in Cellular Neuroscience·DateJun 19, 2017

Gut bacteria may hold key to treating autoimmune disease

Researchers discovered that replacing missing gut bacteria or restoring a key metabolite called inosine could help treat children with IPEX syndrome, an often fatal autoimmune disease. The study found that probiotic Lactobacillus reuteri and A2A receptor agonists inhibited T cell-mediated autoimmunity, extending the animals' life span.

SourceRockefeller University Press·JournalJournal of Experimental Medicine·DateDec 19, 2016

Gut bacteria differ between obese and lean youth

A new study has identified a connection between gut microbiota and fat distribution in children and teenagers, with obese youth having different microorganisms living in their digestive tracts. The research suggests that short-chain fatty acids produced by certain gut bacteria can contribute to the development of obesity.

SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateOct 3, 2016

Pesticides used to help bees may actually harm them

A study published in Frontiers in Microbiology found that pesticides applied to hives to control Varroa mites can damage the gut microbiome of honeybees, impacting their ability to metabolize sugars and peptides. The research suggests that these chemicals can specifically harm the microbes crucial for honey bee nutrition and health.

SourceVirginia Tech·JournalFrontiers in Microbiology·DateAug 8, 2016

Children with and without multiple sclerosis have differences in gut bacteria

A recent study reveals differences in gut bacteria between children with and without multiple sclerosis. Key findings include an association between MS and increased inflammatory bacteria, as well as decreased anti-inflammatory bacteria. The discovery may pave the way for new therapeutic approaches by identifying novel drug targets.

SourceWiley·JournalEuropean Journal of Neurology·DateMay 16, 2016

How cold -- and a bacterium -- fight obesity

Researchers at Université de Genève found that cold exposure alters microbiota composition, leading to increased brown fat activation, improved insulin sensitivity, and weight loss. The discovery highlights the key role of Akkermansia muciniphila in regulating nutrient absorption and may lead to new anti-obesity treatments.

SourceUniversité de Genève·JournalCell·DateDec 3, 2015

Differences in treatment effect on out-of-balance microbiome in Crohn's disease

A study by researchers at the University of Pennsylvania School of Medicine found that different treatments for Crohn's disease in children have distinct effects on their gut microbiome. The use of antibiotics suppressed bacterial growth but facilitated fungal growth, while immunosuppressant medications reduced inflammation and bacteri...

SourceUniversity of Pennsylvania School of Medicine·JournalCell Host & Microbe·DateOct 14, 2015

A whale of a tale

Scientists have discovered that the gut microbiome of right whales and other baleen species shares traits with both cows and meat-eating predators. This dual microbial community enables whales to digest not only copepods but also their chitin-rich shells, providing a significant nutritional benefit.

SourceHarvard University·JournalNature Communications·DateSep 22, 2015

Protection of the mouse gut by mucus depends on microbes

Researchers found that gut microbiota affects mucus barrier properties in mice, with different microbial compositions leading to varying levels of protection against bacterial invasion. The study suggests that a well-developed inner mucus layer is crucial for overall health and highlights the importance of the gut microbiota composition.

SourceEMBO·JournalEMBO Reports·DateDec 18, 2014