Articles tagged with Microbiota
Researchers observed changes in upper respiratory tract bacterial diversity after COVID-19 infection over time. The study suggests that viral infections can change the respiratory microbiome, potentially predictive of outcomes.
A new microbiome therapeutic, SER-109, has been shown to improve the quality of life of patients with Clostridium difficile (C. diff) infections by reducing symptoms and restoring colonization resistance. The treatment was found to be associated with significant improvements in health-related quality of life scores as early as Week 1.
Researchers found that ospemifene and systemic hormone therapy improve VVA symptoms by reducing harmful bacteria and increasing health-promoting microorganisms. The study also suggests a potential link between the vaginal microbiome and menopause symptoms.
A study by Mayo Clinic researchers found a specific colonization of microbes in the reproductive tract is commonly found in women with ovarian cancer. The discovery strengthens evidence that the bacterial component of the microbiome is an important indicator for early detection, diagnosis, and prognosis of ovarian cancer.
A new system called EasySort AUTO uses artificial intelligence image recognition to sort single bacterial cells, increasing efficiency by over 93% and preserving cell vitality. The technology has been successfully tested on yeast and E. coli bacteria, with over 80% of sorted cells able to be cultured.
Researchers identified a strong association between beneficial bacteria and estrogen hormone therapy in postmenopausal women. The study found that estrogen may play a role in reducing susceptibility to recurrent UTIs by promoting the growth of good bacteria such as Lactobacilli in the bladder. Conversely, women with recurrent UTIs had ...
A new study explores the value of 'trash data' from cancer genome sequencing, identifying new strategies to uncover previously unexplored information. The researchers found that genomic and transcriptomic data contain relevant information that can help elucidate carcinogenesis and discover putative biomarkers with clinical applications.
A new study reveals that COVID-19 causes a significant disruption in vaginal microbiota balance, leading to an increased risk of preterm birth. The research found a 70% change in microbiota and higher levels of pathogenic bacteria in infected women compared to control groups.
Researchers developed a single-cell Raman-based tool to efficiently mine live functional microbes from nature, eliminating the need for traditional culturing methods. This technique, called scRACS-Culture, allows for the direct screening and cultivation of cells with specific metabolic functions.
The study focuses on reducing insects and pathogens that threaten crops, with manure serving as a potential solution. Researchers will investigate the most effective ways to apply manure to improve soil health and plant resistance to insect pests.
Researchers discovered that two approved insecticides can damage honey bees' intestinal flora, making them more susceptible to disease. The study highlights the need for rigorous research on pesticide effects on beneficial insects before approval.
Researchers discovered that plants can regulate their microbiome through the secretion of flavonoids, which affect beneficial and harmful microorganisms around plant roots. This delicate balance helps protect plants from parasitic nematodes, reducing susceptibility to infection.
Researchers have discovered that the bacterial protein BefA stimulates insulin-producing cells to replicate, potentially leading to new treatments for Type 1 diabetes. This finding suggests that the gut microbiome plays a crucial role in regulating beta cell development and preventing autoimmunity.
A new platform has been created using 214,000 microbiome samples to track antibiotic-resistant bacteria globally. The data can be used to tailor guidelines on combating resistance in different regions.
Researchers identified 257 rhizoplane microbial biomarkers associated with six key agronomic traits, revealing a complex association between millet genotype, root microbiome, and crop growth. The study provides insights into precision agriculture based on genotype-dependent microbial effects in foxtail millet.
The event will cover various topics including microbiota dysbiosis, oral and vaginal microbiota, and their impact on diseases like depression, cancer, and respiratory infections. The meeting aims to accelerate Microbiota medicine applications through strategic discussions.
Researchers at KAUST have identified thermophilic bacteria with potential to degrade oil contamination. The study reveals that certain bacteria can secrete surfactants and absorb emulsified petroleum into their cells for degradation via enzymatic activity.
A new study led by NYU researchers has developed a topical gel that targets the succinate receptor to suppress inflammation, reduce bacterial imbalance, and prevent bone loss. The treatment has shown promise in reducing gum disease symptoms, including inflammation and tooth loss.
Researchers found that over 60% of investigated microbial species matched their human host's evolutionary history, indicating a co-evolutionary relationship spanning ~100,000 years. This discovery fundamentally changes how the human gut microbiome is viewed and opens up new possibilities for population-specific therapies.
A study led by Singapore scientists found that Neisseria, a genus of bacteria once considered harmless, can cause infections in patients with bronchiectasis, asthma, and COPD. The research team identified a specific subgroup of Neisseria called N. subflava as the main culprit behind worsening disease outcomes.
A new study found that early life exposure to antibiotics in neonatal mice has long-lasting effects on their microbiota, enteric nervous system, and gut function. This could mean that babies given antibiotics may experience gastrointestinal issues later in life.
Researchers found that soil microbiota facilitates the growth of invasive garden lupine and provides defense against herbivores. The plants grown with natural soil microbes produced compounds that deter snails, while those with reduced microbiota showed no such effect.
New study reveals that subarctic cave bacterial communities are more diverse and complex than surface soil ones, but climate change poses a significant threat to these unique ecosystems. The scarcity of nutrients in caves drives bacteria to cooperate with each other, which may be affected by global warming.
A new study from the University of South Australia shows that captive frogs can be protected from the deadly fungus Batrachochytrium dendrobatidis (Bd) through natural skin shedding processes. However, captivity also reduces skin bacteria diversity and richness, potentially affecting the frogs' resilience to pathogens.
Research in rats found that an enriched environment leads to better maternal behavior and higher-quality breastmilk. Mothers in enriching environments had more efficient parenting, resulting in larger offspring with increased body weights and improved social behavior.
Researchers led by Osaka University found that Fusobacterium nucleatum produces polyamines through metabolic cross-feeding, creating favorable conditions for periodontal pathogens to grow and spread. This integration of a metabolic network within the oral microbiome may promote the development of periodontitis.
A study published in Frontiers in Immunology found that Japanese herbal medicine DKT reduces colitis severity by preventing gut bacteria loss and increasing immune cells. It restores Lactobacillus levels and promotes type 3 innate lymphoid cells, alleviating inflammatory responses.
Researchers found that bioturbation by fiddler crabs increases soil pH and reduces salinity, creating a more hospitable environment for beneficial bacteria. These bacteria produce essential chemicals for iron trapping, improving mangrove plant growth.
A new study from the University of Illinois found that dog gut bacteria can change rapidly after introducing a new diet, with microbial turnover occurring in under a week. The research also confirmed previous findings on the health benefits of high-fiber diets over high-fat and high-protein diets.
A study found that plant genetic variability controls specific microorganisms, influencing microbial community composition and plant reproductive success. The research used Arabidopsis thaliana genotypes and metabarcoding DNA sequencing to analyze the impact of genetics on leaf microbiota.
A new methodology predicts soil recovery after wildfires by analyzing the impact of microbes and nutrients on soil regeneration. The study found that including uncommon soil microbiota was critical to predicting water quality and terrestrial ecosystem recovery.
New research finds that plants with shorter-lived flowers produce more fruits due to reduced microbial growth. Microbes on flowers can negatively impact plant yields.
The 13th Annual Meeting on Skin Challenges 2022 will highlight the roles of extracellular vesicles in skin ageing and age-related diseases. Therapeutic strategies and anti-ageing potential of these vesicles from various sources, including stem cells and commensal bacteria, will be addressed.
A new study uses machine learning models to predict cancer patients' responses to immunotherapy based on their gut microbiome features. The research identifies common gut bacterial taxa associated with responders versus non-responders, providing a potential tool for distinguishing and predicting immunotherapy responders.
Researchers found that domesticated maize recruits different microbes from soil than its wild ancestors, including those involved in nitrogen cycling. This shift may be driving the need for synthetic fertilizers, but understanding the ancestral microbiome could help breed crops more sustainably.
The 15th World Congress on Polyphenols Applications will be held in Valencia, Spain from September 28-30, featuring over 100 communications and discussions on polyphenol applications and innovations. The congress aims to explore the role of polyphenols in food and their impact on human health.
Dr. Jennifer Hampton Hill's work shows that restoring lost bacterial cues in the gut can stimulate development of insulin-producing cells, potentially protecting against autoimmune destruction associated with Type 1 Diabetes. The discovery of a specific protein, beta-cell expansion factor A (BefA), holds promise for human beta-cells.
Researchers found that the microbiome of sea anemones changes as they adapt to changing temperatures, making them more resistant to heat stress. The transfer of these altered microbiomes from acclimated to non-acclimated animals also led to increased tolerance to high temperatures.
A team of ecologists from CU museum identified over 7,000 organisms, mostly bacteria, in the guts of Rocky Mountain snails collected between 1920 and 2018. The findings show that microbiomes can offer insights into how animals interacted with their environments centuries ago.
Researchers found that short-term cover crop use cannot reverse decades of soil microbial dynamics in response to unsustainable practices. Long-term fertilization disrupted nitrogen cycling communities, while cover crops enhanced biodiversity but had both positive and negative effects on soil microbes.
A new study from University of Minnesota Medical School suggests Fecal Microbiota Transplantation (FMT) is an optimal and cost-effective treatment option for the first recurrent Clostridioides difficile infection. The research model indicates it's effective and cost-effective when used in patients after a single episode of recurrent CDI.
Research reveals antibiotics can knock out essential gut bacteria, leading to reduced motivation and endurance in athletes. The study found that high-performance mice were more affected by antibiotic treatment, highlighting the microbiome's impact on exercise behaviors.
Researchers have discovered that soil microbes use distinct metabolic pathways to metabolize carbon in different soils, challenging long-held assumptions in the field of soil ecology. The study suggests that these differences may be related to protection against oxygen stress in certain environments.
Researchers found a 1000-fold increase in skin microbiota and larger lesions after smallpox vaccination, but all groups had equal protection from re-infection. The study suggests that manipulating commensal skin microbiota might enhance the efficacy of intradermal vaccines.
The 9th World Congress on Targeting Microbiota 2022 will focus on recent advances in the microbiota field and therapeutic strategies. Key findings include research on probiotic strains, natural mineral waters, and extracellular vesicles.
Researchers found varied diversity of gut microbiomes among brown bears at three national parks in Alaska, with Katmai showing the most diversity due to its diverse food sources. The study advances understanding of wildlife habitat, diet, and gut microbiome diversity.
A recent study found that yellow perch can expel microplastics from their bodies, but the process reduces nutritional value and alters liver function. The fish also experienced changes in gut microbiota communities and reduced body protein and mineral levels.
A recent study has found a link between high carbohydrate intake and the diversity of oral bacteria in postmenopausal women. The researchers also discovered associations between sugar consumption and certain types of gum disease, such as gingivitis. These findings suggest that diet may play a role in the development of periodontal dise...
The Experimental Biology (EB) 2022 meeting features live presentations and a moderated Q&A session on groundbreaking studies. The virtual press conference reveals potential treatments for Parkinson's disease, COVID-19 vaccine-associated side effects, and alleviating food allergies.
Researchers discovered that shorter antibiotic courses are associated with fewer antibiotic resistance genes in children, but also found increases in resistance to other antibiotics. The study suggests that treatment duration can impact the microbiome and increase susceptibility to other pathogens.
Researchers discovered a link between the immune system and microbiome in primary sclerosing cholangitis (PSC), a liver disease associated with inflammatory bowel disease. MAIT cells activated by bile-derived pathogens could play an important role in PSC pathophysiology, offering potential new treatment implications.
Research suggests that changes in the microbiome may play a role in both the development and progression of pancreatic cancer. A distinct gut microbial profile was observed in patients with ductal pancreatic cancer compared to those without the disease, and this signature consistently identified patients regardless of disease stage.
Researchers identified a molecular signature of 27 microorganisms in stool samples that can predict pancreatic ductal adenocarcinoma risk and diagnose earlier stages. The study suggests a non-invasive, rapid, and affordable diagnostic kit could be developed to detect the disease.
Researchers discovered that tadpoles raised without helpful microbes can't stand the heat, and are five times more likely to die in high temperatures. The team also found that microbes help tadpoles deal with heat by regulating their metabolisms and energy production.
Researchers have identified a way to improve bacterial vaginosis treatment by targeting the vaginal microbiome. By analyzing over 1,200 vaginal Lactobacillus genomes and growing a novel strain of Lactobacillus iners in the lab, scientists discovered that this species requires external cysteine sources, which can be blocked using inhibi...
Researchers from Tohoku University developed a new approach to treating intractable diarrhea in calves by harnessing the power of fecal microbiota transplantation (FMT). The study identified key factors, including Selenomonas and Sporobacter, that facilitate successful FMT treatment.
Researchers analyzed the gut microbiome of 1,241 middle-aged individuals and found that about half of the bacterial species were modified by drug treatment, while 75% of disturbances occurred in early stages of overweight and type 2 diabetes. The study suggests that an imbalanced gut microbiome may play a role in heart disease development
Harris Wang, a synthetic and systems biologist at Columbia University, received the Vilcek Prize for Creative Promise in Biomedical Science for his development of tools to track and engineer microbes. His research aims to improve diagnostic and therapeutic applications using genomic technologies.
A Caltech-led team of researchers discovered that a bacterial metabolite can travel to the brain and alter its function, leading to increased anxiety in mice. The study provides a molecular explanation for recent observations linking gut microbiome changes to complex emotional behaviors.
A team of researchers discovered that chance plays a significant role in the formation of individual gut microbiomes, with genetic, diet, and environmental factors influencing the odds of colonization. The study's findings have major implications for treatments like fecal transplants and probiotics.