Articles tagged with Microbiota
A new study from University of Minnesota Medical School suggests Fecal Microbiota Transplantation (FMT) is an optimal and cost-effective treatment option for the first recurrent Clostridioides difficile infection. The research model indicates it's effective and cost-effective when used in patients after a single episode of recurrent CDI.
Research reveals antibiotics can knock out essential gut bacteria, leading to reduced motivation and endurance in athletes. The study found that high-performance mice were more affected by antibiotic treatment, highlighting the microbiome's impact on exercise behaviors.
Researchers have discovered that soil microbes use distinct metabolic pathways to metabolize carbon in different soils, challenging long-held assumptions in the field of soil ecology. The study suggests that these differences may be related to protection against oxygen stress in certain environments.
Researchers found a 1000-fold increase in skin microbiota and larger lesions after smallpox vaccination, but all groups had equal protection from re-infection. The study suggests that manipulating commensal skin microbiota might enhance the efficacy of intradermal vaccines.
The 9th World Congress on Targeting Microbiota 2022 will focus on recent advances in the microbiota field and therapeutic strategies. Key findings include research on probiotic strains, natural mineral waters, and extracellular vesicles.
Researchers found varied diversity of gut microbiomes among brown bears at three national parks in Alaska, with Katmai showing the most diversity due to its diverse food sources. The study advances understanding of wildlife habitat, diet, and gut microbiome diversity.
A recent study found that yellow perch can expel microplastics from their bodies, but the process reduces nutritional value and alters liver function. The fish also experienced changes in gut microbiota communities and reduced body protein and mineral levels.
A recent study has found a link between high carbohydrate intake and the diversity of oral bacteria in postmenopausal women. The researchers also discovered associations between sugar consumption and certain types of gum disease, such as gingivitis. These findings suggest that diet may play a role in the development of periodontal dise...
The Experimental Biology (EB) 2022 meeting features live presentations and a moderated Q&A session on groundbreaking studies. The virtual press conference reveals potential treatments for Parkinson's disease, COVID-19 vaccine-associated side effects, and alleviating food allergies.
Researchers discovered that shorter antibiotic courses are associated with fewer antibiotic resistance genes in children, but also found increases in resistance to other antibiotics. The study suggests that treatment duration can impact the microbiome and increase susceptibility to other pathogens.
Researchers discovered a link between the immune system and microbiome in primary sclerosing cholangitis (PSC), a liver disease associated with inflammatory bowel disease. MAIT cells activated by bile-derived pathogens could play an important role in PSC pathophysiology, offering potential new treatment implications.
Research suggests that changes in the microbiome may play a role in both the development and progression of pancreatic cancer. A distinct gut microbial profile was observed in patients with ductal pancreatic cancer compared to those without the disease, and this signature consistently identified patients regardless of disease stage.
Researchers identified a molecular signature of 27 microorganisms in stool samples that can predict pancreatic ductal adenocarcinoma risk and diagnose earlier stages. The study suggests a non-invasive, rapid, and affordable diagnostic kit could be developed to detect the disease.
Researchers discovered that tadpoles raised without helpful microbes can't stand the heat, and are five times more likely to die in high temperatures. The team also found that microbes help tadpoles deal with heat by regulating their metabolisms and energy production.
Researchers have identified a way to improve bacterial vaginosis treatment by targeting the vaginal microbiome. By analyzing over 1,200 vaginal Lactobacillus genomes and growing a novel strain of Lactobacillus iners in the lab, scientists discovered that this species requires external cysteine sources, which can be blocked using inhibi...
Researchers from Tohoku University developed a new approach to treating intractable diarrhea in calves by harnessing the power of fecal microbiota transplantation (FMT). The study identified key factors, including Selenomonas and Sporobacter, that facilitate successful FMT treatment.
Researchers analyzed the gut microbiome of 1,241 middle-aged individuals and found that about half of the bacterial species were modified by drug treatment, while 75% of disturbances occurred in early stages of overweight and type 2 diabetes. The study suggests that an imbalanced gut microbiome may play a role in heart disease development
Harris Wang, a synthetic and systems biologist at Columbia University, received the Vilcek Prize for Creative Promise in Biomedical Science for his development of tools to track and engineer microbes. His research aims to improve diagnostic and therapeutic applications using genomic technologies.
A Caltech-led team of researchers discovered that a bacterial metabolite can travel to the brain and alter its function, leading to increased anxiety in mice. The study provides a molecular explanation for recent observations linking gut microbiome changes to complex emotional behaviors.
A team of researchers discovered that chance plays a significant role in the formation of individual gut microbiomes, with genetic, diet, and environmental factors influencing the odds of colonization. The study's findings have major implications for treatments like fecal transplants and probiotics.
Researchers at Medical University of Vienna discovered that certain microbiome profiles following lung transplantation can provide prognostic information for future changes in lung function. Machine Learning analyzed multiomics data, including the microbiome, lipidome, and metabolome, to predict lung function deterioration.
A Brazilian berry has been found to enhance the effectiveness of a popular cancer treatment by modifying the gut microbiome. Researchers discovered that castalagin, a polyphenol from the camu-camu fruit, improves immunotherapy response in mice with resistant cancers.
A University of Ottawa review provides the first field-wide summary of how pesticide exposure affects social bee gut microbiotas. The study found that pesticides disturb microbial communities, leading to a loss of benefits and potential decline in bee health and performance.
Researchers at TUM discover that intestinal bacteria interact with Paneth cells in the gut mucus layer, leading to chronic inflammation. This finding may lead to new treatments for IBD.
Beneficial gut microbes transfer genes to acquire vitamin B12, increasing their ability to survive. This process, called bacterial sex, allows them to form a tube that DNA can pass through to another cell, demonstrating the horizontal gene exchange among microbes.
A recent study found that cover cropping can reduce the population of Pseudomonas syringae, a common bacterial pathogen affecting agricultural crops. The researchers also discovered an increase in beneficial microbes such as Sphingomonas and Methylobacterium, which have been used as biocontrol agents against pathogens.
Research found that viral infections in newborns affect immune system development and microbiome composition, increasing risk of respiratory infections later in life. Early-life viral encounters may set the tone for subsequent non-beneficial host-microbe interactions, affecting long-term respiratory health.
Researchers discovered that Black women have a greater relative abundance of Actinobacteria, associated with reduced insulin sensitivity and elevated inflammation. The study highlights the importance of understanding the role of gut microbiome in cardiometabolic health disparities among Black women.
Researchers found that seed microorganisms have more staying power than soil microorganisms when colonizing plants. The study suggests that modifying the seed microbiome could lead to more sustainable agriculture and increased crop yields and quality.
Research shows that common medicines have distinct effects on gut bacteria, with some having beneficial and others detrimental impacts. The study found associations between certain medications and changes to the gut microbiome, particularly with statins and gastric acid medication.
Researchers found that gut microbiome changes can reduce b-amyloid deposits in male mice, indicating a potential target for preventing and treating dementia. Daily fecal matter transplants restored the pre-antibiotic microbiome, suggesting microglia memory plays a role.
Researchers discovered that these 'meat-eating' bees have a unique gut microbiome enriched with acid-loving bacteria, similar to those found in vultures. The bees' ability to eat dead bodies is surprising, but they can also store honey and have special chambers for meat storage.
Researchers have identified specific skin microbiome bacteria and their pathways as contributing to ageing skin. The study, published in PLOS ONE, used a novel approach to chart host-microbe co-metabolism in skin aging.
A recent study published in Annals of the Rheumatic Diseases reveals a link between systemic lupus erythematosus and an altered gut microbiome. Researchers at Osaka University identified two species of Streptococcus bacteria significantly increased in SLE patients, which can affect the body's functions by altering plasma metabolites. T...
Researchers found that children tend to have similar levels of sulfur volatiles in their saliva as their parents, suggesting shared oral microbiomes. Children who produce high amounts of sulfur volatiles dislike raw Brassica vegetables the most.
Researchers at UC San Diego School of Medicine are studying the impact of antibiotics on breast milk and infant health. The team will investigate how antibiotics alter the composition of breast milk and impact the infant microbiome, metabolome and immune response.
A study compared four common DNA extraction methods and found that each method produced slightly different results due to varying 'how' factors. Researchers can now make informed decisions about their methods to optimize results.
A study published in International Journal of Environment and Public Health Research reveals that oral bacteria, specifically P. gingivalis and Lactobacillaceae families, are associated with periodontitis. Genetic differences among hosts contribute to susceptibility to pathogens, but the oral microbiome plays a more significant role in...
Scientists found that rain-borne microbes can successfully colonize plants' aboveground microbial communities, protecting them from stressors. The study suggests that rain is a potentially important reservoir for phyllosphere bacteria, which could be used to improve plant health.
Wastewater screening at UC San Diego detects 85% of COVID-19 cases early, enabling timely testing, contact tracing, and isolation. The approach has reduced campus positivity rates to less than 1% during the pandemic.
A recent study investigated the relationship between switchgrass and soil microbes, revealing that each cultivar harbors a unique community of bacteria and fungi. The research found that root characteristics, such as length and diameter, differ among cultivars and may influence soil microbiomes.
A Horizon 2020 project aims to develop an efficient biotechnological production platform that creates synergy between strain engineering strategies and microbiomes. The project will create novel treatment options in biomedicine beyond biotechnology, leveraging the resilience of microbial communities and their metabolic plasticity.
A global study found that each city has a distinct microbial signature, with over 4,246 known species identified. The research also revealed a core set of 31 species found in 97% of samples across urban areas.
Research finds that a balance between immune-suppressive and non-suppressive bacterial strains in the plant microbiota is crucial for maintaining microbe-plant homeostasis. This balance allows plants to promote growth while preventing excessive defense, reducing disease susceptibility.
A comprehensive map of the citrus microbiome has been created, outlining its structure and potential functions. The study reveals that key microbes dominate different niches of the plant, such as the rhizosphere, rhizoplane, endorhiza, and phyllosphere.
Ravi Sheth, a 27-year-old Hertz Fellow, won the 2020 Hertz Thesis Prize for his groundbreaking work in understanding and engineering complex microbial communities. He developed new tools to quantify how microbiomes change over space and time, revealing universal principles that apply to other physical systems.
A new study found that plant genetics, tissue type, and management strategy play a crucial role in shaping the plant microbiome. The research discovered that bacterial communities are most diverse in the soil, while fungal communities are more evenly distributed across different tissues.
A new study on the Northern Star Coral reveals its ability to recover from laboratory-induced stress, shedding light on coral resilience. Researchers found that coral with algal symbionts recovered their mucus microbiomes more consistently and quickly.
A new study found that decades of corn breeding led to a degradation of sustainable nitrogen-fixing microbes in the soil, contributing to increased greenhouse gas emissions. The researchers recreated the history of corn breeding from 1949 to 1986 and found modern corn varieties recruit fewer beneficial microbes than earlier varieties.
Dr. Kelly Haas is studying the structure, stability, and resilience of the hand microbiome in collaboration with GOJO Industries. Her goal is to understand how the hand microbiome responds to hand hygiene events and develop new products that minimize the trade-off between public health and personal hand health.
Researchers found that treating apple flowers with specific bacteria strains reduced fire blight symptoms, altering floral microbiomes and disease rates. The study suggests that flowers may be a key site for biocontrol interventions, offering a new approach to managing this damaging disease.
Researchers at Utah State University used a new tool to study the effects of stress on Pseudomonas chlororaphis O6, a health-promoting bacterium found in dryland wheat roots. The study found that stress can cause compositional changes in the bacteria's outer membrane vesicles, which may be leveraged for crop benefit.
A Rutgers study reveals widespread antibiotic overuse due to misconceptions and pressure from patients, leading to drug-resistant bacteria and harm to the microbiome. The study also finds that older physicians are more likely to prescribe antibiotics, while misinformation among the public perpetuates unnecessary use of antibiotics.
A new study on sourdough starters from around the world found that geography doesn't play a significant role in shaping their microbial ecosystems. Instead, variables like starter age, feeding frequency and storage conditions have smaller effects that add up to make a big difference.
The new search engine enables researchers to compare different samples with the same function in various microbiomes, aiding disease diagnosis and treatment. MSE 2 includes an extended database of over 260,000 samples, providing a bird's eye view of the microbiome data space
Researchers at Stockholm University found that oak acorn microbes are inherited by seedlings, promoting growth and protecting against diseases. This discovery opens up new possibilities for breeding super plants with improved genes and microbial communities.
A new sequencing-based approach has been developed to determine infection clearance and microbiota recovery. The technique has shown promise in understanding the activity of microbial drug resistance mechanisms and identifying causative microbes.
A large study challenges the conventional practice of administering antibiotics before C-section incisions, finding them equally effective when given after clamping. This discovery may benefit newborns' developing microbiomes, potentially affecting immune system development and future health.
Certain bacteria living in sorghum roots work together with the plant to reduce drought stress, leading to overall plant success. The microbiome plays a critical role in determining crop productivity, and manipulating it may hold the key to developing crops that can thrive in harsh conditions.
A study found that urban daycare children developed more diverse microbiomes and signs of a better-regulated immune system after playing in renovated yards with natural forest floor. The intervention improved immune regulation and health-associated commensal microbiota among 3-5 year olds.