Articles tagged with Arteries
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A subgroup analysis from VOYAGER PAD found that adding clopidogrel to rivaroxaban and aspirin after lower extremity revascularization procedures did not provide any added clinical benefit for patients with peripheral artery disease. Instead, it increased the risk of bleeding events.
A 10-year study found no significant differences in death, heart attack, or stroke rates between cardiac stenting and CABG for patients with left main coronary artery disease. However, more patients receiving a stent needed a repeat procedure to unblock the same artery.
A rare case of a giant right atrial myxoma with dual blood supply from the left and right coronary arteries was reported. The tumor was successfully excised via open-heart surgery, with no recurrence during a 3-year follow-up.
Only 19.8% of Americans have rapid access to endovascular thrombectomy for stroke treatment, highlighting a significant unmet need in stroke care. Researchers evaluated two strategies to optimize access and found that the bypassing model could improve access by 16.7%, making it an optimal solution for resource-strapped areas.
Researchers identified key features and events over four phases of recovery in mice with surgically narrowed arteries, creating signposts for understanding PAD and developing treatments. By using multiple imaging methods, the study aims to facilitate more optimal approaches to treatment and improve diagnosis.
Researchers at Harvard Medical School have discovered a control mechanism in the brains of mice that ensures adequate blood flow to areas of heightened neural activity. The study found that arteries actively regulate neurovascular coupling and that the protein Mfsd2a plays a critical role in this process.
Scientists at Kanazawa University developed a novel method to detect invisible blood vessels inside tumors, which could help surgeons avoid hemorrhage during tumor resection. The new system uses a master-slave surgical robot with a force sensor that detects pulsation based on gripping force, even in soft and hard tumors.
A small study found that consuming flavanol-rich cocoa improved walking distance and blood flow in patients with peripheral artery disease. The study suggests that cocoa may be a new way to treat PAD, which affects over 8.5 million people nationwide.
The study evaluated nationwide data from 2003 to 2016, assessing changes in the risk profiles and number of patients undergoing revascularization. It found an increase in elderly patients, racial minorities, and those with lower income, as well as a decrease in the use of coronary artery bypass grafting.
Between 2005 and 2014, the number of veterans hospitalized due to critical limb ischemia decreased by 17%, with mortality rates dropping from 12% to 10%. Patients who underwent revascularization procedures were 55% less likely to die and 77% less likely to undergo amputation.
Researchers found a strong association between gum disease and large artery strokes, as well as severe brain blood vessel blockages. Gum disease may contribute to the development of atherosclerosis, a condition characterized by hardening of blood vessels.
A petition to the FDA suggests that ED drug labels should recommend a plant-based diet to prevent artery disease and its related risks, including heart attacks, strokes, and early death. A recent meta-analysis found that men with ED have a higher risk of coronary heart disease and stroke compared to those without symptoms.
Researchers at Oxford University have found a protein called Plexin D1 that detects disturbances in blood flow and triggers inflammation and plaque formation, leading to serious health problems. The discovery offers new hope for developing treatments to block plaques before they form.
A new study reveals that high-protein diets can lead to increased plaque buildup in arteries, particularly unstable plaque prone to rupture. This can increase the risk of heart attacks. Researchers found that excess amino acids from a high-protein diet activate macrophages, leading to cell death and worsening plaque complexity.
A new US study demonstrates the effectiveness of genicular artery embolization (GAE) in treating osteoarthritis knee pain. The minimally invasive procedure blocks blood flow to certain parts of the knee, providing rapid relief from pain and disability. Results show significant improvement in pain scores, with nearly all patients experi...
Researchers at USC Viterbi's Department of Biomedical Engineering have developed a nanoparticle that lights up calcification, allowing for more effective detection of blocked arteries. This innovation has the potential to improve cardiovascular disease diagnosis and treatment by identifying unstable calcifications.
A study found that AI can accurately measure coronary artery calcium, a marker of heart disease, in patients getting lung cancer screening CT scans. The system uses deep learning to automate the assessment, making it easier for doctors to decide on preventative therapy.
Scientists at UVA aim to uncover the origin and development of coronary heart disease using a genetic variation associated with ID3 gene, with potential for personalized treatments based on patient's genotype
A study of nearly 65,000 patients has found that paclitaxel-coated devices are safe and not linked to an increase in deaths. The analysis, which is the largest of its kind, suggests that drug-eluting stents and balloons have no increased risk of death over long-term follow-up.
A recent international trial showed that patients requiring emergency heart attack treatment also benefit from further intervention to reduce the risk of future heart attacks. The study found that additional stenting for significant narrowings in other untreated arteries significantly reduces the risk of future heart attacks and death.
A new imaging study of ancient mummies found that their arteries were more clogged than thought, indicating heart disease was prevalent among human ancestors. The study used near-infrared spectroscopy to detect cholesterol buildup in the arteries, revealing a prevalence of cholesterol-rich plaques even in people at a relatively young age.
A study published in the Journal of the American Heart Association estimates that black men have a 30% lifetime risk of peripheral artery disease (PAD), while Hispanic men have a 22% risk. The researchers developed a risk calculator to identify high-risk patients who may benefit from PAD diagnostic screening.
A study of nearly 9,800 NY firefighters suggests an association between greater exposure to the World Trade Center disaster and long-term cardiovascular disease risk. Both acute and repeated exposure during work at the site are linked to higher cardiovascular disease risk compared to those with less exposure.
Research in mice reveals that XX sex chromosomes increase blood fat levels, leading to narrowed arteries and higher heart attack risk. The study suggests a new therapeutic target for treating coronary artery disease in post-menopausal women.
Researchers developed a 'fat fingerprint' using machine learning to identify inflammation, scarring, and changes to blood vessels. The new biomarker can predict heart attacks with higher accuracy than current tools.
A new study published in the New England Journal of Medicine shows that opening all clogged arteries after a serious heart attack leads to a 26% reduction in patient risk of dying or having a recurrent heart attack. This approach also shows no major downside to additional procedures.
A new study found that left-ventricular hypertrophy is a stronger predictor of heart failure than coronary artery calcium score. The study analyzed data from 6,814 men and women with no known heart disease and found that LV hypertrophy increased the risk of CHD events by 4.3 times.
A Yale-led study reveals that transforming growth factor beta (TGFß) proteins trigger inflammation in endothelial cells, leading to plaque buildup and atherosclerosis. Disrupting TGFβ receptors with RNAi drug reduces inflammation and plaque effectively.
Research finds that patients from areas with cleaner air are more sensitive to changes in pollution, while those from more polluted cities can adapt to fluctuations. A higher incidence of PCI procedures was observed in winter and rose along with increasing pollution.
Researchers at University of Texas at Austin are developing noninvasive computational modeling technology to assess heart attack risk. The project uses computer simulation technology to analyze individual patients' vulnerability to plaque rupture, which can trigger a heart attack.
A recent study by the University of Pennsylvania School of Medicine found that nicotine-free e-cigarettes can immediately reduce vascular function and impair blood flow. The researchers used MRI exams on healthy adults to measure changes in blood vessels after vaping a single e-cigarette, revealing significant damage.
A study published in JAMA finds that measuring carbon dioxide levels through an artery is more accurate than using end-tidal capnography for pediatric brain trauma patients. The protocol developed by the Harborview Injury Prevention and Research Center has been widely used at Harborview Medical Center.
Recent research highlights the importance of treating epicardial coronary artery abnormalities that do not result in myocardial ischemia. Aggressive risk factor modification and drug use are recommended for individuals with such conditions.
The latest issue of Cardiovascular Innovations and Applications features a wide range of papers on various cardiovascular topics. These include studies on selective coronary angiography following cardiac arrest and systemic vasculitis as an underestimated cause of malignant hypertension. The journal also covers reviews on epicardial co...
The American Heart Association has released new guidelines for diagnosing and treating critical limb ischemia, a condition that affects an estimated 12 million Americans. The guidelines aim to improve the precision and quality of critical limb ischemia management through non-invasive techniques and devices.
Patients transported by mobile stroke unit receive clot-busting procedure an average of 10 minutes faster than standard ambulance, potentially saving up to 270 million neurons per patient. The quicker treatment can restore blood flow and save neurological function.
Researchers found that anti-inflammatory biologic therapies can significantly reduce coronary inflammation in psoriasis patients, using a novel imaging biomarker. The study has implications for other chronic inflammatory diseases, such as lupus and rheumatoid arthritis.
Researchers at Stanford University School of Medicine have discovered that specific cells in artery walls transform to form protective caps on plaque, reducing the risk of rupture. The new discovery sheds light on atherosclerosis progression and potential prevention strategies.
A new study found that cigarette smoking significantly increases the risk of peripheral artery disease, which can persist for up to 30 years after quitting. Compared to never-smokers, smokers had a fourfold increased risk of developing peripheral artery disease.
A study of over 500,000 people found that naturally higher iron levels are associated with reduced risk of high cholesterol and atherosclerosis. However, the research also revealed potential risks, including increased risk of blood clots and bacterial skin infections.
A new study from the University at Buffalo found a significant association between long-term exposure to air pollution and the severity of coronary artery calcium, or plaque buildup in artery walls. The study suggests that China may need to revise its standard for nitrogen dioxide limits to reduce the risk of cardiovascular disease.
Researchers at Charité - Universitätsmedizin Berlin found that non-invasive coronary computed tomography (CT) angiography is equally accurate to catheter angiography for diagnosing coronary artery disease. The study suggests that CT angiography can be a suitable diagnostic technique for patients with low to intermediate probability of ...
A new machine learning approach using coronary CT scans shows better results than existing models in predicting heart attacks and cardiac events. The study found that the AI-based method can identify patients at higher risk more accurately, leading to improved treatment outcomes.
A study by Goethe University Frankfurt has demonstrated the safety and efficacy of non-invasive magnetic resonance imaging (MRI) in guiding therapy decisions for patients with stable chest pain and coronary heart disease. MRI measurements were found to be as safe as cardiac catheterization, with reduced need for invasive procedures.
A new study suggests that elevated estrogen levels in early pregnancy can lead to placenta abnormalities, but treating pregnant women with the growth factor VEGF could halt preeclampsia and preterm birth. Researchers found that VEGF treatment increased uterine artery remodeling and improved blood flow to the placenta.
A team of UK scientists has identified the mechanism behind hardening of the arteries, which is associated with dementia, heart disease, high blood pressure, and stroke. They found that a generic medication normally used to treat acne could be an effective treatment for the condition.
A new study published in Diabetologia found that type 2 diabetes in midlife is associated with a 30% increased risk of serious brain artery blockage leading to stroke. Additionally, individuals with T2DM at ages 40-59 years had double the risk of cerebral occlusion and a 30% higher risk of cerebral infarction.
A study of over 8,000 people in the UK found no association between moderate to heavy coffee consumption and arterial stiffness. The research, led by Queen Mary University of London, suggests that coffee may not be as detrimental to heart health as previously thought.
A new nerve stimulation therapy may provide a new treatment option for the most common type of stroke. The study found that this active nerve cell cluster stimulation reduced patients' degree of disability three months after they suffered an acute cortical ischemic stroke.
A new study by Johns Hopkins Medicine researchers found that 10% of people who rated themselves in excellent health had measurable cardiovascular disease without symptoms. Combining self-reported perceptions with definitive risk tools like coronary artery calcium scans provides a more accurate indication of heart health.
Researchers found that injections of a novel protein called VEGF-C 152S reduced artery blockage by about 30% and made plaque more stable, potentially reducing strokes. The protein targets the lymphatic system, which is understudied in atherosclerosis.
Researchers at Morgridge Institute for Research have successfully grown smooth muscle cells from pluripotent stem cells using a novel growth factor called RepSox. This breakthrough reduces the risk of intimal hyperplasia, a common cause of graft failure in bypass surgery.
Imaging techniques like cardiac MRI and intravascular imaging can help diagnose the underlying cause of MI in women without obstructive CAD. These methods provide crucial information for treatment decisions.
Researchers identified 27 new metabolites associated with arterial stiffness in a large study of over 1,200 participants. The study found that certain lifestyle factors, including coffee drinking and Southern foods, were linked to increased levels of these metabolites.
Researchers at Boston University School of Medicine examined coatings on drug-coated balloon catheters using microscopy and cell cultures to improve delivery efficiency. They found that coating shape affects drug transfer, leading to better device performance and potential outcomes.
Researchers found that older heart attack patients were less likely to receive timely percutaneous coronary intervention (PCI) to open blocked heart arteries, resulting in more complications and poorer outcomes. Despite longer hospital stays, older patients had lower total charges due to reduced use of costly interventions like PCI.
A new study published in Radiology found that bariatric embolization produces significant weight loss and reduces appetite for up to one year. The procedure involves blocking arteries with beads to suppress hunger-stimulating hormones. Researchers saw encouraging signs of metabolic changes, including improved quality of life.
Researchers evaluated the safety and effectiveness of uterine artery embolization (UAE) in patients with various autoimmune diseases. UAE was technically and clinically successful in all patients, with no significant difference in volume reduction rates between groups.
Researchers found that people with PAD had a lower Omega-3 Index compared to those without the disease. The study suggests that omega-3s may play a role in preventing the development of PAD. Further studies are needed to determine whether long-term use of omega-3 supplements can prevent PAD.
Research suggests that an aging microbiome may be the key to understanding vascular decline and cardiovascular disease risk. The study found that suppressing the microbiome in old mice restored vascular health to that of young mice, highlighting the potential for gut-friendly diets and supplements.