Articles tagged with Arteries
A new study found that 44% of micro-arteries from patients had abnormal myogenic tone, associated with excessive caldesmon presence and poor cell alignment. This abnormality affects blood supply within the heart and other organs, impacting quality of life and life expectancy.
Researchers have developed a special polymer to coat blood vessels on transplanted organs, reducing rejection rates in mice by substantially diminishing immune system response. The breakthrough has the potential to eliminate the need for drugs that prevent organ rejection and improve transplant outcomes.
Researchers found that a mobile interventional stroke team treated patients faster and with better outcomes than standard care. Patients treated by the MIST team were more likely to be functionally independent at 90 days post-stroke.
A study found that women with severe large vessel occlusion ischemic strokes are approximately 11% less likely to be sent to comprehensive stroke centers compared to men. Stroke severity, travel distances, and comorbidities were similar between genders.
A recent study by the AIDS Clinical Trials Group found that nearly half of participants had atherosclerotic plaque in their coronary arteries, despite being considered at low-to-moderate risk. The study also revealed an association between plaque presence and higher levels of inflammation independent of traditional risk scores.
A recent Finnish study found that higher levels of moderate and vigorous physical activity can reduce arterial stiffening in childhood. The study, which followed 245 children aged 6-8 years over two years, showed a positive association between increased physical activity and more elastic arteries.
Researchers develop a new method for reducing X-ray exposure during coronary angiography procedures by applying video interpolation techniques to frame rates. The approach uses a dataset of 95,039 images and achieves significant reductions in X-ray exposure frequency.
A new statewide study in Michigan found that smokers needed their blocked arteries fixed nearly a decade earlier than non-smokers, with patients with obesity undergoing procedures four years earlier than non-obese patients. The study suggests that preventing smoking and obesity could delay the onset of heart disease.
A new physiological measurement of heart function, PAPP, has been shown to identify high-risk patients with systolic heart failure or pulmonary hypertension. This monitoring technology can reduce the risk of death by 46% annually in patients with low PAPPs.
A global health problem has been identified as microvascular angina, a disease affecting the smallest heart blood vessels. The study found that patients with MVA experience chest pains similar to those of a heart attack, yet are often misdiagnosed due to the lack of definitive diagnostic criteria.
A new type of coronary artery stent is being developed with ultra-low profile struts and a smart surface that can help improve healing and prevent blood clots. The stents aim to reduce the risk of restenosis and thrombosis, which occur in 3-10% of cases.
Researchers have developed a new approach to analysing the forces at play behind diseased heart vessels, which could help cardiologists predict heart attacks in patients. The study used optical coherence tomography images to generate patient-specific reconstructions of coronary plaques and analyse stress concentrations.
Research reveals that prenatal detection of heart defects is less likely in rural, low-income areas and among Hispanic women. Diagnosing heart defects before birth reduces infant death rates and improves outcomes.
The study found that rivaroxaban significantly reduced the occurrence of total severe events in patients with symptomatic peripheral artery disease who underwent lower extremity revascularization. The treatment also showed a 12.5% absolute reduction in risk for adverse events in this high-risk population.
A study published in the New England Journal of Medicine found that FFR-guided PCI had no significant benefits for STEMI patients with multi-vessel disease and was more expensive than angiography alone. The FLOWER-MI trial enrolled 1,171 patients who underwent a second stenting procedure after a STEMI heart attack.
A new study shows that a potassium ferrate hemostatic patch reduces the time to hemostasis after cardiac catherization, making it safer and faster to remove compression bands. This finding has the potential to change practice and enable same-day discharge protocols for patients.
Researchers at MUSC developed an AI software to predict CAD blockages' significance without catheterization. The software analyzes CT images of heart vessels and plaques, estimating blood flow and identifying high-risk features. This noninvasive method saves time, costs, and risks for patients and clinicians.
A comparative study found that Heat not Burn products may cause reduced endothelial function and increased oxidative stress in users, similar to conventional cigarette smokers. The study suggests that these products should not be recommended for smoking cessation or as a less harmful alternative.
A recent University of Guelph study found that early cannabis use may be linked to an increased risk of developing heart disease. The research, which analyzed data from 35 young subjects aged 19-30, revealed subtle but potentially important changes in heart and artery function among cannabis users.
Researchers found that high blood pressure alters artery structure, facilitating atherosclerosis development and increasing accumulation of LDL cholesterol in human-like arteries. Keeping both LDL cholesterol and blood pressure low is crucial for preventing atherosclerosis.
A new study found that high-intensity exercise with induced ischemic leg pain improves walking performance and distance in people with peripheral artery disease. Participants who walked at a pace causing discomfort showed significant improvements in six-minute walk distance and treadmill time.
Researchers have identified a genetic link to clogged arteries, finding that a specific gene variant increases the risk of coronary artery disease, high blood pressure, and diabetes. The discovery provides new insights into the causes of cardiovascular disease and offers potential therapeutic targets for treatment.
Genicular artery embolization (GAE) significantly reduces inflammation, improving quality of life for people with moderate to severe knee pain. The procedure provides long-term, safe pain relief, with benefits seen as early as three days post-treatment and lasting up to one year.
Kytai Nguyen's research aims to reduce complications and improve quality of life for PAD patients by delivering plasmids that protect cells and promote new blood vessel growth. The project has the potential to offer hope to millions worldwide affected by this common malady.
A new study published in Hypertension Journal Report found that a structured exercise program improved artery health and function in middle-aged and older men with low-to-normal testosterone levels. The study showed no benefits from testosterone therapy on artery health.
Researchers developed a next-generation nanotherapy that specifically targets injured regions of arteries in mouse models mimicking angioplasty. The nanoparticles containing an microRNA switch offer promising biotechnology to advance the fight against atherosclerotic cardiovascular disease.
New research from the University at Buffalo suggests that satisficers, who make minimal decisions, may feel incapable of managing their choices due to stress. This approach is often misunderstood as being less particular or careless, but rather a defense mechanism against overwhelming decision-making stress.
Research published in the American Heart Association's Circulation Journal found that women with a history of gestational diabetes during pregnancy have a two-fold higher risk of coronary artery calcification, a strong predictor of heart disease. Attaining healthy blood sugar levels after pregnancy does not decrease this risk.
A new AI algorithm developed by Brigham and Women's Hospital can automatically measure coronary artery calcium from routine CT scans, predicting cardiovascular events like heart attacks. The system was validated in over 20,000 individuals and highly correlated with manual scores, showing promise for personalized medicine.
A 66-year-old woman experienced a pseudoaneurysm and median nerve injury after radial artery puncture, leading to severe pain and swelling in the affected arm. The authors discuss causes and treatment measures for this complication of radial artery puncture.
Patients diagnosed with non-cardiac chest pain often struggle to accept normal test results due to misconceptions about heart disease. A new study shows that a brief educational intervention significantly improves patient trust and reduces future chest pain episodes.
Researchers at CNIC have identified a novel cellular and molecular mechanism that promotes vascular arterialization, enabling the development of arteries from blood capillaries. This breakthrough has significant implications for treating cardiovascular diseases, including coronary artery disease and myocardial infarction.
A large study of over 2,300 patients found that paclitaxel-coated balloons and stents do not increase mortality rates compared to conventional devices. The results resolve a long-standing debate on the safety of these treatments for peripheral arterial disease.
A study published in PLOS Medicine found that a Mediterranean diet improved endothelial function and reduced damage to the arteries in patients with coronary heart disease. The diet, rich in monounsaturated fatty acids, was shown to reduce the risk of another heart attack by half.
A recent study found that only about 60% of patients with coronary artery disease, stroke, or peripheral artery disease receive the recommended statin therapy. Despite a decrease in drug cost, disparities persist in statin use among different age groups, genders, and racial backgrounds.
A new approach to guiding heart bypass surgery is being tested on patients for the first time, using non-invasive CT scans. The FAST TRACK CABG study aims to simplify treatment for coronary artery disease patients.
Subcutaneous S-ICD therapy is explored as an option for patients with congenital heart disease and high risk of sudden cardiac death. A case study reports successful S-ICD implantation in a patient with ccTGA and DDD pacemaker, without interference between systems.
A pediatric patient with anomalous origin of the left coronary artery from the pulmonary artery developed severe heart failure at 3 months old. The authors review a case and discuss the challenges in early diagnosis, highlighting the importance of considering ALCAPA as a differential diagnosis.
Researchers found that combining ticagrelor and aspirin is more effective than either medication alone in preventing another stroke in patients with heart plaque. The study showed a 27% reduction in stroke risk among these patients, highlighting the potential benefits of this combination therapy.
Researchers found that additional imaging tests revealed hidden causes of heart damage and inflammation in 84% of women with MINOCA, a type of non-obstructive coronary artery disease. The study suggests that women are more likely to have this condition than men, and it has the potential to guide medical therapy for secondary prevention.
The ALPHEUS trial found no significant difference in periprocedural heart attack and complications between ticagrelor and clopidogrel in patients undergoing elective PCI. The study suggests that ticagrelor should be reserved for acute coronary syndrome cases, not those with stable heart conditions.
The latest issue of Cardiovascular Innovations and Applications (CVIA) features research articles on COVID-19, including a study predicting death in severe patients. The journal also publishes papers on the impact of ventricular pacing and Marfan syndrome diagnosis.
Researchers found in situ pulmonary artery thrombosis associated with radiation therapy has unique imaging characteristics and does not typically embolize. The study identified 27 patients with PAT after RT, highlighting the importance of radiologist awareness for accurate diagnosis and management.
A significant increase in the prevalence of the median artery has been observed in humans since the late 19th century. This trend is attributed to genetic mutations or health problems during pregnancy, and may continue to rise, with a majority of people expected to have the median artery by 2100.
A study by Michigan Medicine researchers found that the baroreflex, a neural response to changes in tension, may be contributing to high blood pressure in some rats. The team observed that the baroreflex appeared to switch on and off for extended periods of time, which can predict hypertension in these animals.
A new electronic stent design is being developed to continuously monitor coronary artery disease in real-time, providing a unique solution to prevent restenosis. The device will offer long-term monitoring capabilities without the need for frequent follow-up visits.
Researchers at North Carolina State University developed a prototype vascular graft that combines synthetic fibers and collagen filaments to aid in regeneration of the coronary artery lining. The design showed improved strength, flexibility, and biological response compared to previous models.
A deep learning model can quickly identify large vessel occlusions, which account for a significant proportion of ischemic strokes. The algorithm's sensitivity was found to be 100%, outperforming single-phase CTA in detecting these critical blockages.
A team from the University of Pittsburgh is using a $1.1M grant to optimize small-diameter tissue-engineered vascular graft design and manufacturability. They aim to develop a feasible alternative to decades-old vessel harvesting methods, with the goal of reducing complications like stenosis.
A recent study published in Circulation: Cardiovascular Imaging Journal found that biologic therapy for psoriasis can significantly reduce high-risk plaque in heart arteries over a one-year period. The treatment was associated with an 8% reduction in coronary plaque, similar to the benefits of statin therapy.
A genome-wide association study identified specific genetic regions associated with SCAD, which also predict the risk of SCAD among individuals with fibromuscular dysplasia. The findings suggest a shared genetic basis for migraine headache and SCAD, highlighting the need for further research into its clinical implications.
Research published in the Journal of the American Heart Association found that PAD patients with depressive symptoms have a poorer recovery rate. Women are twice as likely to be depressed than men. The study highlights the importance of integrating mental health screening and treatment into chronic disease management for optimal outcomes.
A University of Houston researcher has identified sphingomyelinase as a key player in the development of obesity-induced cardiovascular disease. The study aims to develop therapeutic strategies for treatment or prevention of this condition, which affects millions worldwide.
A six-week course of a PCSK9 inhibitor improved coronary artery function in people living with HIV or high cholesterol, increasing area and blood flow. The study suggests a potential way to limit cardiovascular disease risk in these populations by improving blood vessel function.
Researchers from Brigham and Women's Hospital developed a new, lower threshold for pulmonary vascular resistance to diagnose patients at risk for death due to PH. The study found that 60% more patients can be diagnosed with PH using this new parameter.
The study analyzed 150 patients' cranial CT scans and identified three types of angular arteries, with the artery's depth varying by age. The findings suggest that injecting hyaluronic acid into elderly patients requires special caution to avoid damaging the artery, which can be exposed due to fat volume loss.
A new study found that 12 weeks of passive leg stretching improved blood flow and reduced stiffness in arteries. This non-invasive technique could serve as a new drug-free treatment for improving vascular health and reducing disease risk.
A study by University of Colorado Boulder researchers found that TMAO, a compound produced in the gut from red meat metabolism, impairs artery function and hastens aging. Adults with higher blood levels of TMAO had significantly worse artery function and greater signs of oxidative stress.
A large national database found that nearly 40% of patients who didn't use opioids before undergoing coronary artery bypass grafting or heart valve procedures developed persistent opioid use afterwards. The study suggests that cardiac surgery may be a contributing factor to the development of opioid dependence in some individuals
Researchers found that patients with peripheral artery disease or stroke were less likely than those with coronary artery disease to receive recommended treatments to prevent heart attack. Lifestyle changes and medication, including statins and aspirin, are crucial for all three types of atherosclerotic cardiovascular disease.