Research on how the brain is built and how it governs body and behavior. Covers neural circuits, sleep, sensory systems, brain structure, and the brain-body connection.
Researchers at Åbo Akademi University have discovered a crucial protein, TLNRD1, that helps maintain blood vessel stability in the brain. The study highlights the potential for targeted molecular therapies to improve patient outcomes in CCM disease.
Researchers have discovered a link between cognitive impairments and brain network organization in individuals at risk of developing psychotic disorders such as schizophrenia. This finding suggests an opportunity for early diagnosis and intervention, potentially through non-invasive neuromodulation.
Researchers found that non-lawyers use complex legalese when writing laws, and it signals a sense of authority. The 'magic spell hypothesis' suggests that this style is used to convey power and legitimacy, making documents more difficult to understand.
Researchers successfully restored the brain's waste-clearing process by reviving cervical lymph vessel function in aging mice, utilizing a known drug to boost efficiency. This breakthrough could pave the way for future therapies targeting neurodegenerative diseases.
A study published in Neuron reveals that neurons are wired to connect seemingly unrelated concepts, enhancing the brain's ability to predict what we see based on past experiences. Visual experience influences the organisation of feedback projections, which store information about the world.
Seoul National University researchers developed a biodegradable electronic tent technology that enables non-invasive brain disease diagnosis using a needle. The device unfolds to cover the entire brain over a large area and naturally decomposes in the body after diagnosis, minimizing side effects.
Researchers from Eötvös Loránd University found temperature and humidity have no impact on dogs' ability to detect scents. However, indoor testing outperformed outdoor environments due to distracting stimuli. Age also plays a role, with 2-3 year old dogs exhibiting superior olfactory performance.
A recent study published in Nutrition and Health suggests that following a Mediterranean diet can lower perceived stress levels. The research, conducted by Binghamton University, found an association between consuming Mediterranean diet components and reduced mental distress.
The Rice University lab has developed a new noninvasive technique, called REMIS, that can measure gene expression and gene therapy delivery in specific brain regions using ultrasound. This technology could revolutionize brain-based gene therapy for neurodegenerative diseases.
Researchers discovered how cocaine affects the dopamine transporter, a protein that regulates dopamine levels in the brain. This knowledge could pave the way for medical treatments for cocaine abuse and potentially other addictive substances.
Researchers developed a new visual diagnostic technique called Cap-QuIC that can distinguish infected samples with the naked eye, enabling faster and more accurate disease detection. The method builds upon previous groundbreaking diagnostic techniques and leverages simple action to detect misfolded alpha-synuclein proteins.
A new editorial published in Aging suggests that starting targeted cancer therapies with high concentrations may slow down the selection for resistance. This approach could potentially be used as a preemptive measure to minimize the development of resistance.
Researchers have identified nearly 300 common and over 20 rare genetic variants as significant risk factors for schizophrenia. The study emphasizes the role of multiple genes rather than single-gene causation, revealing complexity in the mechanisms underlying the disorder.
A clinical trial found that fish oil supplements slowed neuronal integrity breakdown in older adults with the APOE4 gene variant, a risk factor for Alzheimer's disease. The study showed no benefit for all older adults, but suggested omega-3 fatty acids may be useful for prevention.
Researchers at Mayo Clinic used AI to analyze electroencephalogram (EEG) tests, identifying subtle brain wave patterns characteristic of cognitive problems like Alzheimer's disease. This technology has the potential to provide healthcare professionals with a more accessible tool for early diagnosis in communities without easy access to...
A new study finds that combining an inhibitor of a metabolic pathway with chemotherapy could improve treatment outcomes in triple negative breast cancer brain metastases. Inhibiting fatty acid synthase, an enzyme critical for cancer cell survival, shows promise in improving chemotherapy efficacy.
Researchers found that combining plasma p-tau217 and Aβ42/40 levels could predict early brain Aβ accumulation in people with subthreshold Aβ accumulation. These biomarkers may help screen participants for primary prevention trials.
A new drug has shown promise in clearing HIV from the brain by targeting infected cells and reducing viral load. The treatment, BLZ945, successfully cleared the virus from brain tissue, providing a potential new avenue for HIV treatment.
A recent study published in Nature Communications found that mammals with more developed brains tend to exhibit smaller sexual size dimorphism (SSD), meaning there is less difference in size between males and females. This suggests that complex brain development may be linked to other traits such as social behavior and mate selection.
Researchers found that epigenetic state affects neurons' recruitment into memory trace formation. Open chromatin states enable more efficient learning. The study opens new avenues for understanding learning and may lead to medication for improving cognitive disorders.
A new Reichman University study demonstrates how external representation of physiological signals can improve internal balance. The researchers created an immersive multisensory environment that mirrors the user's breathing pattern, leading to significant improvements in interoceptive sensibility and flow among users.
Researchers study T cells and monocytes interaction in the meninges before they attack the brain and spinal cord, potentially leading to new disease progression targets. The findings could provide a pathway to treating other neurological diseases like Alzheimer's and Parkinson's.
Wanja Wiese's research focuses on ruling out deception by conscious AI systems and understanding the prerequisites for consciousness in artificial systems. He draws on Karl Friston's free energy principle, suggesting that computers can simulate consciousness but may require additional conditions to replicate conscious experience.
The UNLV study found that brain activity patterns change with the number of experiences, not time, and that increasing speed affects perception. The research suggests that our brains register a 'vibe' about time, making it faster when we're having fun or doing tasks efficiently.
Studies in glassfish reveal that vision plays a crucial role in coordinated schooling behavior, with maturity also essential for developing this ability. Researchers discovered that older fish can distinguish between movement patterns of their social partners, allowing them to align their bodies and swim together effectively.
Activation of the brain's reward system may improve recovery from a heart attack by reducing infarct scarring and improving clinical outcomes. The study found that stimulation of the reward system resulted in favorable modulation of the immune response within the damaged myocardium, leading to an improvement in cardiac performance.
Researchers discovered that propofol, a commonly used anesthesia drug, induces unconsciousness by causing the brain to become increasingly unstable. This instability leads to chaotic brain activity, resulting in loss of consciousness. The study's findings could help develop better tools for monitoring patients during general anesthesia.
Researchers from Jilin University provide a comprehensive overview of brain injury biomarkers, including neuron-specific enolase, ubiquitin C-terminal hydrolase-L1, and neurofilament proteins. These biomarkers can help identify brain injuries and predict disease progression.
Dr. Rissman's research uses plasma Aβ42/Aβ40 ratio to predict brain amyloid PET positivity and identify individuals at risk for Alzheimer's disease. His findings demonstrate the potential of a blood test to screen for amyloid in preclinical AD trials.
Researchers at Wake Forest University School of Medicine have been awarded a five-year, $27 million grant from the National Institute on Aging to study the connections between heart health and brain health. The study will examine how cardiovascular disease contributes to Alzheimer's disease and other dementias.
A recent study published in iScience found that newborn chicks are predisposed to learn quicker based on the colour of their mother. The research team discovered a colour-dependent bias in learning speed, with chicks exposed to a deep blue mother learning faster than those raised by mothers with other colours.
A previously unknown mechanism in the brain causes migraine attacks by carrying proteins to specific nerve cells, explaining one-sided headaches. The discovery may lead to new treatment options and help understand other headache diseases.
Researchers from UniSA and Deakin University found a link between rooms with high ceilings and poorer examination results. The study analyzed data from 15,400 undergraduate students, comparing their exam scores to ceiling heights, and found lower scores when sitting exams in larger rooms.
Researchers at the University of Birmingham found that people are aware when their brain is filling in gaps with generic information, enabling them to factor in this knowledge when assessing memory accuracy. The study suggests individuals can recognize prototypical memories and distinguish them from accurate ones.
Researchers explored Cognizin Citicoline's effects on neurons, astrocytes, and microglia, revealing its potential as a supplement for cognitive decline. The study's findings suggest that Cognizin Citicoline may support brain health and cognitive function.
A study published in Gut reveals that specific bacteria in the gut are involved in compulsive eating and obesity, with a beneficial bacterium called Blautia showing protective effects. The research also highlights the role of microRNAs in food addiction and suggests potential new treatments involving beneficial bacteria and dietary sup...
Researchers found that humans distinguish between voices based on emotional cues, with happy voices being perceived as more human-like. However, the brain's response differs, with AI voices eliciting stronger responses in error detection and attention regulation areas.
Researchers found that hospitals that implemented standardized protocols from the American Heart Association and American Stroke Association saw significant reductions in stroke treatment times. The protocols, which include specific limits on time between symptom onset and hospital arrival, helped medical teams respond more quickly to ...
A new study found that animals use a wide range of strategies to accomplish tasks, many of which are just as effective as the optimal solution but require less brain power. The research provides a theoretical framework for understanding these 'good enough' strategies and their potential applications in animal behavior.
A new model developed by Flatiron Institute researchers proposes that individual neurons exert more control over their surroundings, which could be replicated in artificial neural networks. This updated model treats neurons as tiny 'controllers' and may lead to better AI performance and efficiency.
Scientists are conducting a clinical trial to explore the use of anti-retroviral medications Ritonavir and Lopinavir as a potential treatment for brain tumors in patients with Neurofibromatosis 2. The study aims to determine if these drugs can help reduce tumor growth and survival in NF2 patients.
Researchers at Bar-Ilan University have discovered a new scaling law that governs how artificial neural networks handle an increasing number of categories for identification. This law reveals how the identification error rate increases with the number of required recognizable objects, impacting AI latency and efficiency.
Researchers used a closed-loop auditory stimulation approach to target alpha rhythms in the brain, revealing that sounds at specific phases can manipulate alpha oscillations. The study's findings suggest that sound stimulation could be used to enhance cognition and sleep in people with dementia.
Researchers found a link between gut microbiota and Parkinson's disease, revealing reduced B vitamins and intestinal barrier issues. Treatment with B vitamins could alleviate PD symptoms and slow disease progression.
A potential new strategy for reducing diabetes risk associated with antipsychotic medications involves co-administering drugs that block dopamine receptors in the brain alongside those that stop these same receptors in the pancreas. This approach may limit metabolic side effects and improve glucose metabolism.
Researchers have made a breakthrough in understanding the GIP hormone's role in regulating insulin levels and weight loss. The study, involving over 500,000 individuals, found that inhibiting the GIP receptor may result in weight loss, while activating it without arresting its signal is crucial.
Researchers at the University of Birmingham discovered a link between dopamine and mentalising abilities in healthy individuals. They found that altering dopamine levels affected participants' ability to accurately attribute mental states, with implications for treating conditions like Parkinson's disease.
The 2024 Kavli Prize Laureates have made significant contributions to our understanding of exoplanet atmospheres, nanoscale materials for biomedical applications, and the localization of brain areas specialized for face recognition. Their work has broadened our knowledge of planetary life beyond Earth.
A recent study reveals that some honeybees exhibit superior learning abilities compared to others, which may be attributed to distinct gene expression patterns in their brains. The research explores the behavioral and genetic underpinnings of individual differences in learning performance among Apis mellifera.
A new review paper explores the mechanistic links between peripheral vascular dysfunction, cerebral vascular dysfunction, and reduced brain health with aging. The study suggests that targeting fundamental aging mechanisms may be a promising strategy to reduce dementia risk.
Researchers created a virtual rodent with an artificial brain that can move like a real rodent, simulating complex behaviors using biomechanical data from real rats. The model uses deep reinforcement learning and AI to predict neural activity across behaviors.
Researchers from Kyushu University discovered new conditions for a three-flash illusion, where the brain misperceives the second flash as near the midpoint between the first and third flashes. This phenomenon occurs regardless of the second flash's location, highlighting the complexity of visual perception.
The NeuroEXPLORER PET scanner offers exceptional brain PET images with ultra-high sensitivity and resolution, showcasing focal uptake in specific brain nuclei. This technology has the potential to spur advances in treating conditions like Alzheimer's disease, Parkinson's disease, and mental illnesses.
Nutrition 2024 will explore the role of diet in exercise performance, brain health, and disease prevention. Researchers will share emerging findings on the relationships between specific foods and chronic diseases.
Researchers studied newborn baboon brain anatomy to predict future gestural communication handedness, finding that nearly 70% developed a right-hand preference. The study suggests a shared evolutionary heritage and potential clinical implications for brain surgery patients.
Research suggests that altered lipid signaling in brain cells contributes to mental disorders, with specific inhibitors showing promise in rebalancing this mechanism. The study found similar changes in both human patients and healthy relatives, as well as mice with genetic disorders, opening up new treatment opportunities.
Researchers used virtual reality to test whether humans can feel embodiment toward prosthetic
A study led by researchers from the University of Arizona Cancer Center identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain. By targeting the autophagy pathway, the researchers were able to disrupt breast cancer cells' ability to form brain metastases.
A team of researchers led by Virginia Tech's Shuhai Xiao discovered a 550 million-year-old sea sponge that challenges previous theories about its evolution. The fossil, found in China, suggests that early sponges may have had soft-bodied skeletons and only later developed mineralized structures.
Researchers discovered that command-like DNs in fruit flies recruit additional networks of neurons to orchestrate complex behaviors. The study shows that these networks work together to produce coordinated actions, transforming the way we understand brain signals and behavior.