The study found that women have a significantly higher prevalence of peripheral artery disease, while men have a higher prevalence of carotid artery stenosis and abdominal aortic aneurysms. Diabetes is also identified as a major risk factor for developing PVD, even in patients without heart disease.
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A 10-year clinical trial found that both surgery and stenting reduce the risk of stroke by about 7%, with low rates of restenosis over time. The procedures are safe and durable for preventing stroke in various patient groups.
A clinical trial found no significant difference in stroke prevention between carotid stenting and endarterectomy for asymptomatic patients. The study, published in the New England Journal of Medicine, included over 1,400 participants with severe carotid artery narrowing.
Researchers found a link between pre-kallikrein levels and thickened blood vessels in type 1 diabetes patients. Elevated plasma PK levels are an independent risk factor for whole-body diabetic vascular disease, similar to high triglycerides or high blood pressure.
A new study using 3-D MRI found that diabetic patients have a higher risk of stroke due to advanced vascular disease, with 23.3% having intraplaque hemorrhage in at least one carotid artery. The finding suggests that 3-D MRI could be useful in determining stroke risk among diabetics.
A study published in JAMA Neurology found that patients with asymptomatic carotid stenosis are not significantly harmed by medical therapy and may even benefit from more intensive treatment. The study's findings suggest that preventing carotid occlusion may not be a valid indication for stenting or endarterectomy.
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Researchers at Johns Hopkins found that re-inflating a balloon in the vessel after stent placement can double the risk of stroke and death. The common practice, known as 'ballooning,' is intended to prevent complications but may actually cause them.
The 'Radial Paradox' reveals that radial access may offset vascular complications when used as a backup method for femoral access. A study found that non-culprit vessels with significant stenosis are not functionally important, increasing debate on intervention strategy. Meanwhile, elderly patients benefit from drug-eluting stents with...
A University of Chicago research team describes the precise mechanism used by carotid body cells to detect oxygen levels and regulate breathing rates. The primary sensor is heme oxygenase-2, which induces synthesis of carbon monoxide to stimulate or relax breathing.
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A new study published in the Journal of the American College of Cardiology found that adding two non-invasive imaging tests to traditional cardiovascular disease risk factor assessment can more accurately predict a healthy patient's future risk of heart attack, stroke, or premature death. The study identified subclinical atherosclerosi...
Researchers analyzed medical test records for over 300,000 people and found a significant link between fine-particulate-matter pollution and stenosis in internal carotid arteries. This study suggests that lowering pollution levels may reduce the incidence of carotid artery stenosis and stroke.
Research suggests chronic exposure to air pollution increases the risk of stroke by causing fatty substances to build up in the neck arteries. The study found those living in areas with high levels of fine particulate matter had a 24% greater risk of carotid artery stenosis compared to those in cleaner areas.
A portable ultrasound study found that nearly a quarter of participants had plaques in at least one artery, with added iliofemoral examination increasing identification by 5%. The technology showed promise for detecting subclinical atherosclerosis before symptoms arise, potentially preventing disease through preventive treatment.
A recent study published in JAMA Neurology found that carotid artery stenting had a 32% mortality rate among Medicare beneficiaries over a two-year follow-up. The study's findings suggest that the benefits of stenting may be limited for high-risk patients, highlighting the need for further research on real-world outcomes.
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Researchers found stenting as effective as endarterectomy for preventing fatal and disabling strokes, with slightly higher risk of minor strokes in the stented group. The study suggests stenting should be offered to more patients under 70 due to its lower risks.
A new study found that imaging can be a cost-effective way to identify people at risk for stroke and help sort patients into invasive or less invasive options. The study used transcranial Doppler sonography to assess cerebrovascular reserve in asymptomatic individuals with carotid artery stenosis.
The US Preventive Services Task Force recommends against screening for asymptomatic carotid artery stenosis due to its high rate of false positives. A systematic review found no evidence that screening improves outcomes, but also identified a small risk of harms such as stroke and mortality.
A new study reveals a correlation between unhappy marital interactions and a higher risk of cardiovascular disease, as well as thicker carotid arteries. The research found that individuals with positive marital interactions had an 8.5% greater risk of heart attack or stroke.
Research published in mBio shows that stress and emotional shock can trigger heart attacks by dispersing bacterial biofilms on arterial walls. Bacteria such as Pseudomonas aeruginosa are found in atherosclerotic carotid arteries, and their dispersion can cause plaque deposits to rupture into the bloodstream.
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Researchers found subclinical disease in half of the studied firefighters, but traditional methods were insufficient, requiring specialized imaging for detection. The study suggests a high risk of cardiovascular disease among firefighters, emphasizing the need for early intervention and prevention strategies.
Researchers have found that narrowing of the carotid artery in the neck without symptoms is linked to problems in learning, memory, thinking, and decision-making. The study compared people with similar risk factors but no narrowing in the neck artery to those with carotid artery narrowing.
A new study found that carotid artery MRI can accurately predict future cardiovascular events, including strokes and heart attacks, in people without a history of cardiovascular disease. The presence of a lipid core in the internal carotid artery was significantly associated with an increased risk of subsequent events.
A small study found that inflating a balloon inside the artery after placing the stent increases patients' risk of low blood pressure, slow heart rate, stroke, or heart attack. Skipping this step may be beneficial in preventing these complications.
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A prospective study found that improved periodontal health slows atherosclerosis progression, while worsening infections parallel increased risk for coronary events. The study suggests a clear relationship between mouth bacteria and thickening of the carotid artery.
Researchers found that the procedure was successful in 89% of patients with symptomatic carotid artery occlusion, allowing for recanalization through imaging examination findings. The study's results suggest a treatment approach based on imaging exam findings can effectively restore blood flow to affected areas.
Researchers at University of Bristol found that removing the carotid body, a small nodule on each carotid artery, reduces blood pressure in rodents with high blood pressure. The discovery has potential to revolutionize treatment for millions suffering from the condition.
A retrospective study from Cleveland Clinic found that patients who underwent stenting of the carotid artery followed by open heart surgery had the best outcomes. The researchers compared three common treatment approaches and found that this combination had significantly lower risks of serious events after one year.
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Physicians at UH Case Medical Center are enrolling patients in the ROADSTER Study, a global clinical trial testing the Silk Road System, a minimally invasive procedure to clear carotid artery blockages. The trial aims to demonstrate the safety and efficacy of this innovative treatment option for high-risk patients.
Researchers found that snorers have a significantly greater intima-media thickness of the carotid arteries compared to non-snorers. The study suggests that snoring may be an early warning sign for cardiovascular disease, potentially leading to atherosclerosis and other serious health issues.
Researchers at the University of Warwick have discovered a potential new treatment to prevent strokes in high-risk patients. Using ultrasound scanning, they found that tirofiban, an anti-platelet drug, can suppress microemboli in patients who have developed clots despite previous treatment with aspirin.
Researchers have discovered that older COPD patients are more likely to develop high-risk carotid artery plaque formations and have a greater presence of vulnerable plaques with a lipid core. This finding highlights the increased risk of ischemic events in these patients.
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Tests for silent neck artery narrowing result in many unnecessary and costly surgical procedures, ultimately saving very few lives. In a high-risk group of 60+ European men, screening may prevent only one stroke at a significant cost.
The ORIGIN-GRACE study found that insulin glargine significantly reduced secondary outcomes of atherosclerosis progression, but had no effect on primary outcomes. Omega-3 fatty acid supplements also showed no significant effect on either outcome.
Researchers developed an ocular pulse amplitude test to detect carotid artery stenosis, a known stroke risk factor. The test could be performed by ophthalmologists during routine exams and may help prevent strokes.
Researchers at Thomas Jefferson University Hospital found carotid artery stenting to be safe and effective in patients over 70, with a low risk of adverse events. The study showed that while the risk increases with age, it remains extremely low even for those aged 85 and above.
A comparative study has found that stenting and surgery for blocked neck arteries are equally effective in preventing repeat blockages. The study showed identical rates of recurring blockage at 5.8% after both procedures, with no significant difference in the risk of stroke.
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Research found re-blockage rates to be low in both stented and surgically-opened carotid arteries, with less than 7% of patients developing repeat blockages after two years. The study suggests that both procedures are durable and equivalent in terms of re-blockage rates.
Researchers analyzed database of symptomatic patients to investigate optimal timing for carotid artery stenting. The study found no significant difference in outcomes between those receiving CAS at 30 days post-event and those receiving it more than 30 days after stroke or TIA.
Researchers found that carotid artery stenting following prior same-side carotid artery revascularization results in lower incidences of in-hospital death, stroke, and heart attack. The study's findings have the potential to change how carotid artery stenosis is assessed and treated.
The PROFI trial found that proximal balloon occlusion resulted in fewer cerebral ischemic lesions compared to filter protection during carotid artery stenting. This reduction was associated with a lower risk of stroke and other major adverse cardiovascular events.
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Researchers at UTHealth successfully performed carotid artery stenting on 10 high-risk patients without complications or deaths. The procedure showed promising results, particularly in patients with symptoms of stroke related to their carotid artery disease.
A surgical procedure aimed at bypassing a blocked brain artery did not lower the subsequent stroke rate after 2 years, compared to those who did not have the surgery. Patients who made it through the first month without a stroke had their risk of subsequent stroke almost cut by three-fourths.
A study published in JAMA found that a surgical procedure to improve blood flow in the blocked artery did not reduce the risk of subsequent stroke after two years. The trial, which included 195 patients, showed no significant difference in stroke rates between those who received surgery and those who received medical therapy alone.
A study analyzing Medicare data found that older patients treated by low-volume operators had a significantly higher risk of death within 30 days after receiving a carotid artery stent. Patients treated early in an operator's career also faced a higher mortality rate.
A study published in the Journal of the American Medical Association found that older patients who underwent carotid artery stenting from lesser experienced physicians had a higher risk of death within 30 days. The study analyzed Medicare data and found that doctors with less than six procedures per year performed worse outcomes.
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Researchers developed an effective way to pinpoint high-risk patients with asymptomatic carotid stenosis using 3-D ultrasound to identify ulcers in the carotid arteries. The study found that three or more ulcers indicated a high risk of stroke and benefited from intervention.
The latest evidence-based vascular medicine provides comprehensive guidance on managing noncardiac vascular diseases, including PAD, carotid stenosis, renal artery stenosis, chronic mesenteric ischemia, and critical limb ischemia. The series of articles offers expert clinicians the tools they need to improve patient care.
Research finds that adolescents and young adults with type 1 diabetes have increased risk of heart attack and stroke due to atherosclerosis in the carotid arteries. The study aims to improve glycemic control and reduce cardiovascular risk factors to prevent cardiovascular disease.
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A randomized trial found women are at more than double the short-term risk of stroke following carotid stenting compared to traditional surgery. This study suggests that sex should be considered when choosing treatment options for carotid disease, as men show little difference in stroke risk between procedures.
Researchers used carbon dating to determine the age of carotid plaques in humans, finding that plaque formation occurs during a relatively short and late time period in life. The study also found an association between low plaque age, higher insulin levels, and instability.
Researchers found that carotid artery stenting (CAS) with embolic protection is a cost-effective alternative to endarterectomy (END), offering reduced post-procedure hospital stay costs. The study results showed lower rates of death, heart attack, major stroke, and repeat carotid revascularization for CAS compared to END.
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Researchers developed a clinical risk prediction rule using factors such as sex, race, and health history to assess the danger of carotid surgery. The CEA-8 rule found that one-fourth of asymptomatic patients were at higher risk than recommended national guidelines, highlighting the importance of weighing individual benefits and risks.
A recent study found that patients undergoing carotid endarterectomy (CEA) can safely continue taking clopidogrel, but bleeding complications are associated with using a Dacron patch. The study analyzed 260 consecutive patients and found no significant difference in operative blood loss between those on clopidogrel and aspirin alone.
New analysis suggests that stenting can perform as well as surgery for treating narrowed carotid vessels, with age being a significant factor. For younger patients (under 70) with symptoms related to the condition, stenting proved effective in reducing stroke risk.
A meta-analysis found that carotid artery stenting was associated with increased risks of short- and long-term adverse outcomes, including stroke, death, and restenosis. In contrast, carotid endarterectomy was linked to lower rates of these complications.
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Successful carotid artery surgery halves the risk of stroke over the next 5 years and provides long-term benefit for up to 10 years. The procedure is recommended for asymptomatic patients under 75 years old who have narrowed neck arteries, as it significantly reduces the risk of disabling or fatal strokes.
A meta-analysis of three trials found that stenting is associated with a higher risk of stroke than surgical endarterectomy, particularly in patients over 70. However, younger patients (under 70) can tolerate both treatments equally well.
Researchers compared two treatments for preventing strokes due to carotid artery disease, but found no clear winner. While surgery may be beneficial for patients who have had a stroke or temporary stroke in the past 12 months, stenting offers similar benefits for asymptomatic patients.
A significant geographic variation was found in the use of carotid endarterectomy and carotid stenting among Medicare beneficiaries, with different regions having varying rates of each procedure. Men and patients with a prior diagnosis of peripheral vascular disease were more likely to undergo carotid revascularization.
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A new study from NYU Langone Medical Center shows that carotid artery ultrasound is a valuable screening tool for diagnosing and excluding coronary artery disease. The non-invasive test can identify severe plaque buildup in the neck arteries, potentially avoiding the need for invasive angiography.