Articles tagged with Muscles
A UK study found a link between long-term use of certain anticholinergic drugs and an increased risk of dementia in patients over 45. The study suggests that clinicians should avoid prescribing these drugs to older patients due to potential cognitive effects.
Researchers at UW-Madison have developed a new approach to noninvasively measure tendon tension while a person is engaging in activities like walking or running. The technology uses vibrational characteristics to assess tendon force, providing insights into motor control and mechanics of human movement.
Researchers found that mid-back muscle decline is associated with increased kyphosis curvature, but not low-back muscle decline. Targeted resistance exercises may help prevent kyphosis progression
Researchers found that children's muscles are more fatigue-resistant and recover faster than those of untrained adults and even well-trained endurance athletes. This discovery may lead to better understanding of how our bodies change from childhood to adulthood and inform the development of athletic potential in children.
Researchers found that Heriaeus melloteei spider venom can block leakage currents through mutated ion channels, potentially treating hypokalemic periodic paralysis. The toxin fixes the voltage-sensing domain of the channel, preventing ions from leaking out and restoring normal muscle function.
A study highlights the importance of strength training for older women to maintain mobility and function. Researchers found that higher physical activity levels significantly improved muscle strength and endurance in both age groups, but particularly in younger women.
A study found that wearing an exoskeleton increases stress on the back by up to 53% and stresses different muscles in the torso by anywhere from 56-120%. Despite relieving arm stress, users reported discomfort due to stiff metal rods in the harness.
A study published by the European Society of Cardiology found that central obesity, even in patients with normal BMI, significantly increases the risk of heart problems. Measuring central obesity can provide a more accurate picture of cardiovascular health than relying solely on BMI.
A recent study found that Tai Chi improves brain metabolism and muscle energetics in older adults. The exercise showed significant increases in neuronal health markers and improved energy production in leg muscles.
A study has found structural and functional changes in muscles of young adults with Type 1 diabetes, leading to reduced metabolism and increased risk of disability.
A new study found structural and functional changes in the muscles of young adults with Type 1 diabetes, leading to reduced metabolism and greater difficulty controlling blood glucose levels. The study suggests revising exercise guidelines for those with Type 1 diabetes to prevent muscle damage.
A new study from McMaster and York universities found structural and functional changes in the power generation parts of the cell, or mitochondria, of those with diabetes. These changes could result in reduced metabolism, greater difficulty controlling blood glucose and accelerated disability development.
The new muscles are made from carbon fiber-reinforced siloxane rubber and have a coiled geometry, lifting up to 12,600 times their own weight. They also support high mechanical stress and exhibit excellent performance when electrically actuated.
A new study found that microgravity during spaceflights has a more significant negative impact on skeletal muscle than low oxygen environments. Researchers suggest that therapeutic and rehabilitative interventions should focus on correcting inactivity rather than hypoxia.
A new study found that individuals with tetraplegia and sleep apnea have distinct responses to airway narrowing, leading to increased risk of sleep disruption. This knowledge can inform targeted therapies for those affected by the condition.
Researchers create StimDust, the smallest deep-tissue stimulator capable of stimulating major therapeutic targets in the peripheral nervous system. The device is powered wirelessly by ultrasound, with an efficiency of 82 percent, and can be implanted in minimally invasive procedures to monitor and treat diseases.
Resistance training increases autophagosome content in young men's muscles, but this effect may be reduced by aging. The study found that UPR is activated by resistance exercise regardless of age, suggesting similar muscle adaptation between young and older individuals.
Researchers at IRB Barcelona found that removing the single mitochondrial protein Opa1 from mouse muscle causes severe inflammation throughout the body, leading to premature death. This study supports the notion that mitochondrial defects underlie diseases of unknown origin involving chronic muscle inflammation.
New research shows that regular muscle stretching can improve blood flow to muscles of the lower leg in elderly people with reduced mobility. This non-invasive exercise technique may help alleviate lower leg problems, such as pain or weakness, and increase walking function in individuals with peripheral artery disease.
A researcher at the University of Pittsburgh is using ultrasound imaging to develop a more precise interface between exoskeletons and individual muscles in people with incomplete spinal cord injuries. This technology aims to provide more efficient rehabilitation tools, reducing the risk of falls during robot-assisted walking.
A new study by Karolinska Institutet reveals that enzyme FIH determines how muscles consume oxygen, with implications for elite athletes and potential new forms of metabolism-affecting drugs.
A randomized clinical trial found that higher protein intake did not increase lean body mass, muscle performance, or physical function in older men. The results suggest that the recommended daily allowance for protein may be sufficient for promoting muscle growth and well-being in this population.
Researchers at Wayne State University are investigating a potential new direction for treating Barth syndrome, a rare and life-threatening genetic disorder. The study aims to activate pyruvate dehydrogenase (PDH) and/or supplement deficient metabolites to reveal a new treatment approach.
Johns Hopkins surgeons develop a modified muscle transplant operation that restores wide and even smiles to selected patients with one-sided facial muscle paralysis. The procedure, published in JAMA Facial Plastic Surgery, shows improvements in smile function, gum exposure, and eye wrinkles.
Replacing naturally occurring molecules could reverse symptoms of aging, potentially influencing exercise capacity and physical endurance. The study found that restoring blood flow to tissues and organs with age could be reversed by replicating the benefits of exercise.
Researchers discovered a glitch in muscle-blood vessel communication that causes vascular aging, which they reversed using NAD+ and SIRT1-boosting treatments. The findings have implications for therapies targeting humans with vascular aging disorders.
Researchers at MIT have found a compound that promotes new blood vessel growth, boosting endurance in elderly mice by up to 80 percent. The study suggests that this restoration of muscle mass could help combat age-related frailty and related conditions.
A new study found that dogs with noise sensitivity and musculoskeletal pain exhibit increased avoidance behaviors and a later age of onset compared to those without pain. The researchers suggest that veterinarians should thoroughly examine dogs with behavior problems associated with noise for potential underlying pain.
A new study found that a Mediterranean diet is associated with higher bone mineral density and greater muscle mass in postmenopausal women. The research, conducted in Brazil, used a food questionnaire and bone scans to measure bone mineral density and appendicular lean mass.
A new study uses brain-computer interface to enhance prosthetic hand control with muscle vibrations, allowing amputees to better control the prosthetic and regain a sense of agency over their movements. The technology has the potential to improve quality of life for those with amputations.
Researchers found that aging muscle shows decreased sensitivity to ADP, resulting in higher levels of reactive oxygen species (ROS) and degenerative loss of muscle mass. Despite exercise resistance training, there were no improvements in age-associated cellular stress.
Researchers identified new genetic clues for enhanced racing pigeon performance through whole genome sequencing and gene expression analysis. They found a polygenic basis for the birds' adaptations, with key genes involved in athletic performance such as CASK, SIK1, and PTPRD.
Researchers have discovered that muscle wasting in old age follows changes in the nervous system, which can be reversed with healthy muscles. The study found that surviving nerves can send out new branches to rescue detached muscle fibers, but this process is not successful in everyone.
Researchers at Syracuse University are making progress in understanding the disease mechanism of ALS by studying ubiquitin and Ubiquilin-2 protein interactions. They found that ubiquitin eliminates droplets of UBQLN2, a protein-encoding gene linked to ALS and dementia.
Researchers from Brigham and Women's Hospital found that zebrafish larvae with a mutation in DDX27 showed reduced muscle growth and impaired regeneration. The study provides specificity to the processes controlling protein synthesis in muscles, which will hopefully allow for targeted treatments for skeletal muscle diseases.
A recent study published in PNAS found that disrupted mRNA transport into axons leads to impaired nerve function and cell death, exacerbating conditions like ALS and spinal muscular atrophy. The researchers identified a noncoding RNA, 7SK, as playing a crucial role in these transport complexes.
A study using worms has discovered the mechanisms involved when multicellular organisms die, particularly as a result of old age. The research found that death spreads through the organism via cellular necrosis, triggered by calcium release, leading to muscle hypercontraction and rigor mortis.
Researchers at the Salk Institute have identified ERRγ as a key player in delivering benefits associated with endurance exercise. By increasing ERRγ, they found that skeletal muscle energy production and endurance were restored, making it a potential therapeutic target for conditions such as muscular dystrophy.
Two US programs, Sportsmetrics and PEP, have been shown to significantly decrease non-contact ACL injury rates and alter dangerous neuromuscular movement patterns in female athletes. These programs improve muscle strength, reduce muscular imbalances, and decrease landing forces.
Patients with non-dialysis chronic kidney disease (CKD) who performed combined exercise showed greater increases in muscle mass and strength compared to those doing aerobic exercise alone. The study found that combining both modes of exercise led to significant health benefits, including increased cardiorespiratory fitness.
Researchers at Karolinska Institutet discover high number of mutations in muscle stem cells impairing cell regeneration, which may result in new medication for building stronger muscles. The study found that physical exercise could clear out cells with many mutations.
Researchers at UBC's Okanagan campus create ultra-stretchable sensor with high sensitivity and durability, suitable for monitoring muscle movement, heart rate, and other bio-signals. The device is capable of sensing and understanding complex human motion, including infinitesimal movements like a heartbeat or finger twitch.
Research reveals that high blood pressure impairs the body's response to hypoxia, limiting oxygen delivery to vital organs and tissues. Middle-aged men with high blood pressure were found to have reduced blood flow to the brain and leg muscles during low-oxygen conditions.
Researchers discovered that cuttlefish can maintain dynamic 3D skin shape for over an hour through a unique muscle tension mechanism. This physiology is thought to conserve energy while camouflaging from predators or waiting for prey.
A study published in PLOS ONE has identified two new muscles in the horseshoe crab's pushing leg and male pedipalp using CT scans, expanding our understanding of this iconic creature's anatomy.
Engineers at Iowa State University created a new smart material that stiffens by up to 300% when mechanically stressed, supporting 50 times its own weight. The material is made from liquid-metal particles that break open under stress, allowing it to reconfigure and change stiffness.
A study by University of Cambridge biological anthropologists reveals that muscle mass is key to regulating heat loss from the hands in cold conditions. Volunteers with higher muscle mass experienced faster rewarming of their hands after exposure to ice-cold water.
Research finds TAK1 is essential for maintaining muscle mass and mitochondrial function in mature skeletal muscle. Removing or reducing TAK1 has negative effects on muscle health, contradicting previous assumptions.
New research reveals that larger hummingbirds can compensate for their greater body masses by adapting their physiology. The study found that acceleration is primarily driven by muscle capacity, while wing size plays a key role in maneuverability.
A new study found that hummingbirds' muscle capacity is associated with better deacceleration, accelerating on a dime, and upward rotations. Wing loading was also linked to rotational movement and turns in general, suggesting that evolved changes in muscle capacity may compensate for relatively small wing size.
A 3-day bed rest study is being conducted to investigate the effects of prolonged weightlessness on human metabolism, specifically insulin resistance. The study's findings could lead to the development of rehabilitation exercises to mitigate these effects and improve astronaut fitness for future Mars missions.
Researchers discovered that certain species of fish, like the little skate, can walk using a neural and genetic developmental program identical to higher vertebrates. The study found conserved genes and neuronal subtypes essential for limb control in these fin-based movement systems.
A new analysis of dozens of studies confirms protein supplements boost muscle mass and strength in weightlifters. However, their effectiveness decreases with age, highlighting the need for greater supplementation as people get older.
A new study published in Cell Reports reveals the lateral vestibular nucleus (LVN) is crucial for maintaining balance in mice. The LVN triggers a two-step response to keep the animal steady, widening its center of gravity and strengthening limb muscles and joints.
A study published in The Journal of Pediatrics reports the use of pyridostigmine to reverse complications from botulinum toxin therapy in pediatric patients. Early treatment with pyridostigmine can alleviate symptoms such as difficulty swallowing or breathing, and patients may regain normal function within days.
US women's perceptions of the perfect female figure have evolved to a thin and toned ideal, according to a recent study led by Frances Bozsik. The research found that recent Miss USA winners are no longer only exemplifying extreme thinness, but also becoming increasingly muscular over the past 15 years.
A UTA researcher has received a $441,000 NIH grant to build new imaging technology that can study blood vessel function in patients with heart failure. This device will use laser light to track oxygen delivery and utilization in muscles, potentially leading to quicker diagnosis and life-saving treatment for these patients.
Researchers provide foundational understanding of myostatin activation mechanism, shedding light on tolloid enzyme's role in generating active myostatin. The study's findings hold promise for developing novel therapies targeting specific structural states of myostatin.
A study published in HortTechnology has found that bad posture can increase loads by 50% on the lower back and double on the shoulders, leaving people susceptible to chronic injuries. The researchers used 3D optical tracking equipment to analyze the movement of gardeners undertaking routine tasks.
A team of researchers at the University of Cincinnati has discovered how myostatin, a signaling protein limiting muscle growth, is activated. This knowledge could lead to new treatments for diseases like muscular dystrophy, ALS, and cancer cachexia.