Researchers at Oregon State University have successfully used gene therapy to aid weight loss in rats without causing significant bone loss. The study, published in the Journal of Endocrinology, found that delivering leptin directly to the brain via gene therapy reduced abdominal fat and preserved bone density.
A study of nearly 400 people found that those with higher dispositional mindfulness had a lower risk of obesity and less abdominal fat. The researchers suggest that increased awareness of thoughts and feelings may help individuals overcome cravings for unhealthy foods and exercise habits.
UK cage fighters are engaging in potentially hazardous behaviors to shed pounds quickly, with two-thirds using 'water loading' and one-third taking diuretics. The researchers warn of increased risk of brain damage from head blows sustained during loss of consciousness.
A new study published in Surgery for Obesity and Related Diseases found that laparoscopic sleeve gastrectomy resulted in significant weight loss in obese pediatric patients with Prader-Willi Syndrome. The surgery showed no apparent negative impact on growth, offering a promising treatment option for these patients.
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Research reveals that healthcare providers' weight loss advice boosts firefighters' weight perception and weight loss attempts. Firefighters who receive weight loss guidance are twice as likely to attempt weight loss and 4.8 times more accurate in their weight perceptions.
A new $6 million NIH grant will fund a WE-CAN study examining the success of community-based programs for treating knee osteoarthritis. The study aims to test the effectiveness of weight loss and exercise interventions in real-world settings, building on previous clinical trial results.
A mathematical calculation platform predicts how patients respond to modified diets depending on their gut microbiome composition. The study reveals that individuals with low-diversity gut microbiomes experience improved blood chemistry when following a weight loss diet.
Researchers at the University of Birmingham found that drinking 500ml of water 30 minutes before main meals led to significant weight loss in obese adults. Participants who preloaded with water lost an average of 1.3kg over 12 weeks, compared to 0.8kg in those who did not.
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A review of survey data from over 300 obese participants found those who rated their primary care doctor's support as helpful lost an average of 11 pounds, compared to just 5 pounds for those with low-rated support. High-quality patient-doctor relationships are linked to better adherence and weight loss outcomes.
A study found that daily liraglutide injections, combined with diet and exercise, resulted in greater weight loss over 56 weeks compared to placebo. Average weight loss was 6.0% with liraglutide (3.0-mg dose), significantly better than the 2.0% with placebo.
The American Heart Association's scientific statement found that mobile health technologies can be effective for managing weight, increasing physical activity, and quitting smoking. However, more research is needed to fully understand their effectiveness for other health conditions.
Researchers found that gastric bypass surgery enhances energy expenditure, allowing patients to lose and maintain weight over time. The study used a metabolic chamber to track the body's energy requirements before and after surgery.
The FDA has approved two new endoscopic bariatric therapies for treating obesity, providing patients with a minimally invasive alternative to surgery. Endoscopic bariatric therapies offer a viable option for patients who have been unsuccessful at weight loss with diet and exercise.
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Researchers use liquid chromatography-mass spectrometry screening to detect sibutramine and sildenafil in supplements. They tested over 100 products, including syrups and capsules sold in China and online.
A new study published in The FASEB Journal suggests that nutritional deficiencies can lead to chronic inflammation, which may be the underlying cause of weight gain. Participants who consumed nutrient bars daily for two months showed significant improvements in various health markers, including weight loss and improved cholesterol levels.
A recent study published in JAMA Surgery found that patients who underwent laparoscopic sleeve gastrectomy experienced significant weight regain and a decrease in remission rates for type 2 diabetes and other obesity-related disorders over time. The study collected data from 443 patients who underwent the procedure between 2006 and 201...
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Cholinesterase inhibitors used to treat dementia can lead to significant weight loss in older adults. Clinicians should monitor patients for weight loss and consider discontinuing these medications if necessary, according to a new study.
A comprehensive study by the American Cancer Society found no association between repeated cycles of intentional weight loss and cancer incidence in men or women. The research suggests that people should be encouraged to try to lose weight despite potential regain, as it may have benefits beyond just weight management.
Two studies published in Gastroenterology found that weight loss through lifestyle modification or bariatric surgery significantly reduces NASH features. Lifestyle modifications resulted in a 10% weight reduction needed to reverse scarring, while bariatric surgery eliminated NASH in 85% of patients after one year.
A study published in the American Journal of Public Health found that obese individuals have a low chance of recovering normal body weight, with only 1 in 210 men and 1 in 124 women achieving this goal. The research highlights the need for obesity prevention strategies to address the rising obesity epidemic.
A new study published in the American Journal of Preventive Medicine found that increasing numbers of overweight adolescents do not consider themselves overweight. This misperception is linked to a decline in willingness to make weight-related behavioral changes, despite being at risk for obesity.
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Research finds that prenatal stress in rats can lead to faster weight loss and reduced hunger signals in offspring, resembling anorexia nervosa. Identifying a specific coping style, passive individuals from stressed mothers were more susceptible to anorexic behaviors, providing insight into potential treatment options.
A nationwide survey of 502 women found that adventurous eaters rated themselves as healthier eaters and were more physically active. They also reported being more likely to have friends over for dinner and were less concerned with the healthfulness of their food.
A recent weight loss study showed significant improvements with liraglutide treatment, resulting in an average weight loss of 8.4 kg. The Temple doctors emphasized that modest weight loss can be considerable and improve medical issues, but more research is needed for longer-term results.
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A study of 61 obese participants with type 2 diabetes mellitus found that bariatric surgery resulted in more disease remission than lifestyle intervention alone. At 3 years, 40% of those who underwent RYGB achieved complete remission, compared to 15% of those who received LAGB and no intensive lifestyle weight loss intervention.
A meta-analysis of 12 randomized controlled trials found that vegetarian diets lead to significant weight loss, with vegan diets showing the greatest results, and benefits attributed to high intake of whole grains, fruits, and vegetables.
A new online computer game has been shown to help people control their snacking impulses and lose weight, with participants losing an average of 0.7kg and consuming around 220 fewer calories a day. The game trains people to associate calorie-dense foods with 'stopping', reducing how much food they eat in laboratory tests.
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Researchers found that weight loss in combination with vitamin D supplementation significantly reduced chronic inflammation. The study, which involved over 200 postmenopausal women, showed that those who lost 5-10% of their baseline weight saw a 37% reduction in inflammatory biomarkers compared to the placebo group.
Severely obese individuals undergoing weight-loss surgery experience substantial improvements in urinary incontinence, with a majority achieving remission three years after bariatric surgery. The more weight lost, the higher the chances of improvement, and those who were older or had severe walking limitations showed less improvement.
A Cornell study found that frequent self-weighing and tracking results effective for losing weight and keeping it off, particularly in men. Losing weight is regained in one year, but maintaining it requires consistent behaviors such as eating less and exercising.
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A randomized trial found that patients assigned a diet they liked lost less weight and reported lower dietary adherence than those assigned a diet by their physician. The study suggests that choosing a diet based on food preferences may make it difficult for dieters to scale down on the amount they eat.
A new study from the University of Copenhagen found that using the intestinal hormone GLP-1 in obesity treatment prevents bone loss and increases blood levels of bone formation markers. This has significant implications for future obesity treatment, particularly for menopausal women at risk of osteoporosis.
A Canadian study found weight loss reduced asthma severity by normalizing or improving airway hyperresponsiveness and quality of life in obese adults. The study supports treating comorbid obesity in individuals with asthma.
A new study from the University of Colorado Anschutz Medical Campus found that a low-cost, non-profit weight loss program offers clinically significant and long-term weight loss results. The TOPS program, which costs just $92 a year, was shown to be effective in maintaining weight loss for over seven years.
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Bariatric surgery not only benefits patients' health but also strengthens their relationships with partners, according to a new study. Couples reported improved intimacy, better conflict resolution, and enhanced sexual relationships after one partner underwent weight loss surgery.
Research at Southern Methodist University found that women nearing ovulation motivated to manage their body attractiveness eat fewer calories. The study adds to the growing understanding of ovulation's impact on women's health and weight management.
A two-year study found that female breast cancer survivors lost an average of 6% of their body weight through lifestyle changes, which may lower the risk of cancer recurrence. The study's results suggest that modest weight loss could become a routine part of oncology care to improve patient outcomes.
A new NIH study reveals that people with certain physiologies lose less weight when limiting calories. Those with a 'thrifty' metabolism, characterized by decreased energy expenditure during fasting, tend to lose less weight during calorie-reduced periods.
A case report suggests that taking an unlabeled stimulant like BMPEA in a sports supplement combined with exercise can cause a hemorrhagic stroke. The patient reported sudden numbness and clumsiness after exercising, highlighting the potential risks of untested stimulants in dietary supplements.
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A new study published in Diabetes Care found that calorie restriction and exercise both improve insulin sensitivity, with combining the two approaches resulting in greater reductions. This suggests that both diet and exercise play important roles in managing Type 2 diabetes risk.
Parental denial of a child's weight issue can hinder efforts to combat childhood obesity. A healthy focus on promoting health and avoiding long-term consequences is recommended instead.
A new study published in the Journal of Health Psychology highlights the disconnect between dieting plans and behavior. Researchers found that people plan to change their eating habits based on thoughts, but when it comes to executing those changes, feelings play a crucial role in guiding behavior.
Patients with rheumatoid arthritis who experience weight loss are at higher risk of early death. The study's findings suggest a potential link between unintentional weight loss and mortality in this patient population.
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A new study presented at The International Liver Congress 2015 shows that significant weight loss through lifestyle changes can improve histological features of non-alcoholic steatohepatitis (NASH). Over 10% weight loss is necessary to induce complete resolution of steatohepatitis, fibrosis, and portal inflammation.
A new study by the University of Sheffield identified six distinct groups of obese individuals, each requiring unique strategies for weight loss and healthy lifestyle promotion. The research suggests that targeting interventions according to an individual's 'type' could lead to more effective and efficient use of NHS services.
While some health apps have shown promise in improving weight loss and physical activity, others have yielded conflicting results. Iltifat Husain argues that doctors should recommend tested and validated apps to help people stay healthy. Des Spence cautions that many health apps are untested and may even cause anxiety and medical harm.
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A new study from Tufts University found that diets high in glycemic load, such as those with refined grains and sugars, are associated with more weight gain. In contrast, protein-rich foods like fish, nuts, and yogurt are linked to weight loss, while dairy products with lower fat content do not seem to impact weight gain.
A review of thousands of studies found that only a few dozen programs meet the scientific gold standard for reliability. Jenny Craig and Weight Watchers showed promise with participants losing more weight than non-participants in trials lasting 12 months or longer.
Researchers found that Weight Watchers and Jenny Craig are the most effective commercial weight-loss programs for long-term weight loss. In contrast, physical therapy was as effective as surgery in alleviating symptoms of lumber spinal stenosis. Leading internists also advocate for a more thoughtful approach to cardiopulmonary resuscit...
New research from the University of Georgia found that physician advice leads to a reported 10-pound loss for women and 12-pound loss for men over a one-year period. Tailored opinions from physicians can help identify obesity risks and promote long-term weight loss.
A two-year study found that workplace wellness programs can effectively reduce the number of people considered overweight or obese by almost 9 percent. Employee involvement in designing and participating in these programs was key to driving broader participation and meaningful improvements in health.
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A Mayo Clinic study found that frequent attendance at work site wellness centers led to significant weight loss and healthcare cost savings. Members who visited the Dan Abraham Healthy Living Center (DAHLC) more than 360 times were 72% more likely to experience weight loss, with corresponding reductions in healthcare costs.
A study by the American College of Cardiology found that obese patients with atrial fibrillation who lost at least 10% of their body weight were six times more likely to achieve long-term freedom from the condition. Sustained weight loss was also associated with significant beneficial structural changes in the heart and improved other ...
A study led by Massachusetts General Hospital investigators suggests that bariatric surgery can significantly reduce the risk of asthma attacks in obese patients. Significant weight reduction after surgery resulted in a half reduction in serious asthma-associated events, including emergency department visits and hospitalizations.
A review of nutrition and weight-loss interventions found a gap in approaches for people with neurological disabilities, who struggle to lose weight due to limited mobility. The study identified 27 behavior-changing techniques targeting weight-loss for people with disabilities, including self-monitoring and managing time.
A recent study found that patients on liraglutide achieved at least 5% weight loss, showing improvements in health markers, blood sugar control, and blood pressure. The results suggest liraglutide as a treatment option for obesity with significant health benefits.
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Researchers found that bariatric surgery patients with high methane and hydrogen levels in their breath had a lower percentage weight loss compared to others. The study suggests that an overgrowth of certain gut microbes may alter metabolism, making it harder to lose weight after surgery.
Research suggests that obese females with high disinhibition scores have impaired metabolism and poorer outcomes due to poor insulin signaling. These women require weight loss treatment more urgently than those with low disinhibition scores.
A new clinical pathway has been shown to significantly reduce complications and improve growth in obese children who undergo weight-reducing procedures. According to the study, the procedure also led to improved management of life-threatening diseases such as diabetes, sleep apnea, and hypertension.
A pilot study suggests that male partners who improve their weight and dietary habits can increase the chances of conceiving with an infertile obese female. The study found that men who lost weight and made healthier lifestyle choices were more likely to conceive than those who did not.