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Cannabis-related emergency department visits by youth increased five-fold in Ontario between 2003 and 2017

A recent study found that cannabis-related emergency department visits among adolescents and young adults in Ontario rose nearly five-fold between 2003 and 2017. The study highlights an emerging public health problem and emphasizes the need for further research into the causes of this trend.

SourceChildren's Hospital of Eastern Ontario Research Institute·JournalCanadian Medical Association Journal·TypeMeta-analysis·DateFeb 8, 2022

Marijuana vaping among youth who use e-cigarettes

A recent study published in JAMA Pediatrics has estimated that a significant proportion of e-cigarette users among youth ages 12 to 24 are also vaping cannabis. The study found an association between cannabis vaping and increased risk of mental health issues, highlighting the need for further research and prevention efforts.

SourceJAMA Network·JournalJAMA Pediatrics·DateFeb 7, 2022

Chronic marijuana use negatively impacts male reproductive health, may decrease testicular function

A new study published in Fertility & Sterility found that chronic marijuana use negatively impacts male reproductive health, leading to decreased testicular size and lowered testosterone levels. The Oregon Health & Science University study used nonhuman primates to assess the effects of daily THC consumption on reproductive function.

SourceOregon Health & Science University·JournalFertility and Sterility·TypeMeta-analysis·DateJan 25, 2022

Young sexual minority men and transgender women are at higher risk of transactional sex

A recent survey by Johns Hopkins Medicine researchers found that about 22% of young sexual minority males and transgender females engage in transactional sex. The practice is associated with HIV exposure, substance use disorder, and unstable housing. Researchers plan to develop interventions to address economic and social vulnerabilities.

SourceJohns Hopkins Medicine·JournalJournal of Adolescent Health·DateJan 25, 2022

Active ingredient in cannabis protects aging brain cells

Researchers found that CBN preserves mitochondrial function and prevents oxidative damage to nerve cells, suggesting potential for treating age-related neurodegenerative diseases like Alzheimer's. The compound works independently of cannabinoid receptors, making it a promising therapeutic option.

SourceSalk Institute·JournalFree Radical Biology and Medicine·DateJan 24, 2022

Largest study to date on delta-8-THC finds users say it's delta-9's 'nicer younger sibling'

A large-scale survey of over 500 delta-8-THC users found they experience fewer negative side effects and use it in safer modalities compared to delta-9. The study's findings have significant implications for lawmakers, public health officials, and consumers as more states legalize cannabis while prohibiting delta-8.

SourceUniversity at Buffalo·JournalCannabis and Cannabinoid Research·TypeSurvey·DateJan 12, 2022

Brain-based method to determine impairment from cannabis intoxication is reported by researchers

Researchers at Massachusetts General Hospital have developed a portable brain imaging procedure using functional near-infrared spectroscopy (fNIRS) to detect acute impairment from THC intoxication. The technique shows promise in distinguishing between impairment and mild intoxication, with accuracy confirmed by machine learning models.

SourceMassachusetts General Hospital·JournalNeuropsychopharmacology·DateJan 11, 2022

January issues of American Psychiatric Association journals cover new research on cannabis and alcohol use, disparities in coercive treatment for psychosis, and more

The January issues of American Psychiatric Association journals feature new research on the factors underlying alcohol and cannabis use, as well as their interactions with other psychiatric illnesses. The journals also address disparities in coercive treatment for psychosis and provide insights into mental health services delivery.

SourceAmerican Psychiatric Association·JournalAmerican Journal of Psychiatry·DateJan 4, 2022

Medicinal cannabis oil found effective for treating autism

Researchers at Tel Aviv University successfully treated autism in animal models with medical cannabis oil, improving behavioral and biochemical parameters. The treatment showed significant improvement in compulsive and anxious behaviors, and a decrease in the concentration of the arousing neurotransmitter glutamate.

SourceTel-Aviv University·JournalTranslational Psychiatry·DateDec 19, 2021

Cannabis use could cause harmful drug interactions

New research suggests that cannabis use can lead to harmful drug-drug interactions by interfering with two families of enzymes that metabolize a wide range of drugs. This could result in unintended side effects such as toxicity or accidental overdose, particularly for older individuals using medications.

SourceWashington State University·JournalDrug Metabolism and Disposition·TypeExperimental study·DateDec 13, 2021

Smoke screen: Analysis of saliva from long-term cannabis smokers identifies disruptions in the healthy oral microbiome that may lead to brain disorders

A study found that long-term cannabis smokers have increased levels of Actinomyces meyeri in their saliva, which correlates with the length of cannabis use. This bacterium was shown to decrease activity and increase beta-amyloid production in mice, suggesting a link between oral microbiome disruption and brain health.

SourceMedical University of South Carolina·JournalEBioMedicine·TypeExperimental study·DateDec 6, 2021

Recent cannabis use linked to extremes of nightly sleep duration

A study of US adults found a link between cannabis use and extremes of nightly sleep duration, with recent users more likely to report short or long sleep. Heavy users were 64% more likely to experience short sleep and 76% more likely to experience long sleep compared to non-users.

SourceBMJ Group·JournalRegional Anesthesia & Pain Medicine·TypeObservational study·DateDec 6, 2021

Why cannabis smells skunky

Researchers discovered a new family of prenylated volatile sulfur compounds responsible for the characteristic skunky smell of cannabis. The findings suggest these compounds could have medicinal properties and are being investigated further.

SourceAmerican Chemical Society·JournalACS Omega·DateDec 1, 2021

Budtenders, healthcare providers seek more training as cannabis use rises sharply in perinatal women

A study found that budtenders and healthcare providers are seeking more training on interacting with pregnant and breastfeeding women about their cannabis use. Healthcare providers have a negative opinion of the effects of cannabis use, while budtenders perceive marijuana as a safer alternative to perinatal alcohol or cigarette use.

SourceWashington State University·JournalThe American Journal of Drug and Alcohol Abuse·TypeContent analysis·DateNov 15, 2021

Cannabis use during pregnancy impacts the placenta and may affect subsequent child development

Research conducted by Mount Sinai Hospital reveals that cannabis exposure in utero can lead to higher levels of anxiety, aggression, and hyperactivity in children. Placental gene expression also shows lower immune-activating genes, predicting these outcomes.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateNov 15, 2021

Study finds alcohol and cannabis sales rose with pandemic

A study published in JAMA Network Open found that monthly alcohol sales increased by an average of 5.5% over expected sales, while cannabis sales surged by 25% during the COVID-19 pandemic. Canadians bought $1.86 billion more alcohol and $811 million more cannabis than predicted based on pre-pandemic trends.

SourceMcMaster University·JournalJAMA Network Open·TypeData/statistical analysis·DateNov 4, 2021

Marijuana vaping among adolescents

A review and meta-analysis of 17 studies found a significant increase in cannabis vaping among adolescents in the US and Canada. The study reported nearly 200,000 participants, with a doubling of reported vaping prevalence over the eight-year period.

SourceJAMA Network·JournalJAMA Pediatrics·DateOct 25, 2021

Cannabis causes birth defects in susceptible mice

A new study reveals that THC can cause birth defects in genetically predisposed mice, highlighting the risks of cannabis consumption during pregnancy. Pups with a mutation in Hedgehog signalling developed brain and face defects, emphasizing the need for further research into human health implications.

SourceThe Company of Biologists·JournalDevelopment·TypeExperimental study·DateOct 5, 2021

With new NIH Small Business Innovation Research Award, scientists at Lewis Katz School of Medicine at Temple University set to test novel cannabis analog in preclinical studies

Scientists at Temple University will explore the therapeutic potential of KLS-13019, a CBD analog that shows promise as an opioid alternative. The Phase 2 SBIR grant aims to test the compound's effects on rat models of neuropathic pain, shedding light on its safety and efficacy.

EMS ketamine use on agitated patients on cocaine increases intubation 5.75-fold

A new study published in Prehospital and Disaster Medicine found that prehospital ketamine administration for excited delirium with concomitant cocaine intoxication significantly increases the risk of subsequent emergency department intubation. The study's findings suggest that cocaine may deplete excitatory neurotransmitters, leading ...

SourceFlorida Atlantic University·JournalPrehospital and Disaster Medicine·TypeObservational study·DateSep 29, 2021

Passage of recreational cannabis laws leads to some rise in use but not for all demographics

A study by Columbia University found that recreational cannabis laws led to increased past-year and past-month cannabis use among Hispanic, Other and non-Hispanic white individuals, but not among non-Hispanic Black people or those aged 12-20. The researchers also highlighted persistent racial disparities in cannabis arrests and incarce...