A new study found that antioxidant nutrients, fruits, and vegetable intake are associated with better ALS function at baseline. The analysis of 302 ALS patients suggested promoting fruit and vegetable intake to support nutritional care.
Researchers found that adding a small amount of Chardonnay grape seed pomace to coffee increases antioxidant capacity without affecting taste or appearance. GSP supplementation can be used to develop a new coffee beverage with potential health benefits.
Researchers found that people who closely follow the Mediterranean diet, especially consuming fruit and caffeine, have a lower risk of age-related macular degeneration. A significant reduction in risk was observed among those with higher diet adherence scores, with only 39% developing AMD compared to 50% of non-adherents.
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Researchers found that combining FLT3 inhibition with drugs inducing oxidative stress improves efficacy against acute myeloid leukemia (AML). This approach, which targets genes involved in antioxidant response, shows promise for combination therapy.
Bovine colostrum exhibits potent antimicrobial activity against Gram-positive and negative bacteria strains. It also demonstrates anti-inflammatory effects, with a combination treatment showing greater benefits than individual treatments.
Researchers have discovered molecules that prevent free radical production by cells, which are implicated in human diseases and the aging process. The findings offer a precise tool to test the free radical theory of aging and could lead to new therapeutic leads for drugs.
Researchers at Joslin Diabetes Center found that the protein IRE-1 can react to ROS molecules, triggering an antioxidant response that increases cell resistance to stress. This discovery highlights the need to consider ROS molecules as links in cell pathways, not just as damaging agents.
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A new review explores potential antioxidant approaches for Alzheimer's, Parkinson's, and other neurodegenerative diseases. Certain compounds targeting oxidative stress pathways, such as Nrf2, are being investigated.
A new drug therapy has been developed that targets pancreatic cancer cells by reducing their antioxidant levels, mimicking the suppression of NRF2. This approach has shown promise in preclinical studies and could provide a novel treatment option for this devastating disease.
Antioxidant supplements have been linked to cardiovascular disease, cancer, diabetes, and other conditions due to their impact on oxygen radicals. However, the review suggests that targeting specific sources of oxygen molecules may be a more effective approach.
Researchers developed a line of mitochondria-targeted antioxidants, SkQ-ions, to protect cardiolipin molecules from oxidation. The study revealed that small doses of synthetic antioxidants could provide a distinct therapeutic effect despite the presence of large quantities of natural antioxidants.
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Scientists at Okinawa Institute of Science and Technology Graduate University identified 14 age-related compounds that decrease with age, including those related to muscle strength and antioxidants. These findings suggest the importance of consuming antioxidant-rich foods and exercising regularly after 65 to improve body conditions.
Researchers found that increasing NADPH levels in cells improved natural antioxidant defenses, reducing oxidative damage and age-related processes. Long-lived transgenic animals showed lower levels of oxidative damage and delayed aging, with increased longevity and better movement coordination.
Researchers have synthesized novel selenohydantoins with promising anticancer and antioxidant activity, leveraging the potential of selenium to slow down oxidation processes. The study's findings highlight the importance of structural modification in influencing biological activity.
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A new study published in the American Journal of Pathology suggests that green tea's antioxidant properties may be compromised when consumed with iron-rich foods or supplements. The researchers found that the main compound in green tea, EGCG, loses its ability to inhibit pro-inflammatory enzymes when bound to iron.
Researchers found that pregnant rats fed antioxidants had longer telomeres and slower aging in adulthood, while those with low oxygen levels aged more quickly. Antioxidants also benefited offspring of mothers without complications during pregnancy.
High-arched palate is under-researched, but researchers developed a reliable technique using a mouse model of Treacher Collins syndrome to study its genetic aspects. The study found that TCS mice exhibited high-arched palates and provided significant criteria for defining the condition.
A University of Tsukuba study found that astaxanthin promotes neurogenesis in the hippocampus and elevates learning and memory capacity. The research discovered specific molecular pathways contributing to improved memory capacity, paving the way for targeted mechanisms in medical food development.
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A recent study published in Scientific Reports found that consuming dried plums can protect against bone loss caused by ionizing radiation. The researchers tested mice using different interventions and found that dried plum was most effective in reducing the breakdown of bone and preventing spongy bone effects.
Researchers found that frying vegetables in Extra Virgin Olive Oil increases their antioxidant capacity and phenolic compounds. The method preserves the natural nutrients of raw vegetables while transferring oil-exclusive phenols.
A study published in Open Chemistry reveals that black raspberries grown in Central Europe have three times more antioxidants than other berries, including phenolics and anthocyanines. This makes them a potential staple for a healthy diet throughout the seasons.
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A recent study by the University of the Basque Country found that altering lettuce growing conditions can enhance its nutritional quality. By subjecting plants to short-duration stresses, researchers were able to boost antioxidant compounds and increase biomass production without compromising productivity.
A study published in Molecular Systems Biology reveals that gut microbiota regulates glutathione and amino acid metabolism in mice, which may contribute to the development of obesity, type 2 diabetes, and other diseases. The research also highlights the potential for probiotics to deliver beneficial bacteria to the gut and prevent meta...
Researchers found that three minutes of high-intensity exercise changes how muscle cells manage calcium, leading to improved endurance. Antioxidants may undermine this effect by removing the breakdown of calcium channels.
A recent study published in the Journal of Food Science discovered that Ceylon gooseberry skin and pulp contain higher antioxidant activity than other berries like blueberries and cranberries. Gooseberry skin may be a source of natural colorants and antioxidants for food manufacturing.
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A review of studies identified 27 natural ingredients that can act as antioxidants in meat and meat products, including Mustard Leaf Kimchi Extract, Oregano Essential Oils, and Carrot Juice. These natural compounds may help preserve the quality and safety of meat products without the use of synthetic additives.
Researchers found that antioxidants can allow melanoma cells to survive and spread more quickly in mice. The study suggests that cancer cells benefit more from antioxidants than normal cells do, raising concerns about the use of dietary antioxidants by patients with cancer.
Research at Sahlgrenska Academy found that antioxidants double the rate of metastasis in malignant melanoma, a type of skin cancer. The study's findings contradict previous assumptions that antioxidants protect against cancer and suggest patients with cancer or an elevated risk should avoid nutritional supplements containing antioxidants.
A study reveals that thymus atrophy may stem from a decline in its ability to protect against DNA damage from free radicals. Common dietary antioxidants may slow thymus atrophy and represent a promising treatment strategy for protecting older adults from infections.
Aging is shown to cripple the production of new immune cells, decreasing the immune response. Antioxidants in the diet may slow this process, suggesting a key role for antioxidants in mitigating age-related immune decline.
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A small study suggests that omega-3 fatty acids and antioxidant supplementation may clear amyloid-beta protein and reduce inflammation in neurological tissues of people with mild clinical impairment. Further clinical studies are needed to verify the findings.
Researchers discovered that high doses of antioxidants can disrupt intracellular signaling in neural stem cells, leading to a decrease in their stemness properties. However, treatment with antioxidants improved stem cell function, but only up to a point.
Researchers found high levels of phenols in spent coffee grounds, which have potential as additives to enhance health effects of other food products. The study's findings suggest that used coffee grounds could be a valuable source of dietary phenolic compounds.
Researchers discover coffee grounds and silverskin contain powerful antioxidants, fibre and phenols, making them suitable for creating healthy food products. The study's findings suggest these by-products could greatly diminish the environmental impact of discarded coffee waste.
Researchers at UNC Chapel Hill use exosomes to deliver catalase, a potent antioxidant that counters neuron-killing inflammation, to the brain. This delivery method bypasses the blood-brain barrier and avoids immune detection.
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Monash researchers, in collaboration with Illycaffè, conducted a comprehensive study on the behavior of free radicals and antioxidants during coffee brewing. They discovered that under certain conditions, coffee can act as an antioxidant, providing a deeper understanding of its potential health benefits.
A study found that different colored lettuces have varying antioxidant effects, with red leaves acting faster than green ones. Researchers aim to boost these properties through short stresses.
Researchers have developed a new technique to retain more antioxidants in chocolate by storing cocoa pods for a few days before fermentation. This process, called pulp preconditioning, resulted in higher antioxidant activity and more polyphenols in the beans.
New research at KU Medical Center found a correlation between milk consumption and increased levels of glutathione in the brain. Participants who drank milk recently had higher glutathione levels, which could help stave off oxidative stress and its associated diseases.
A research team at Montana State University and Sweden has discovered an antioxidant system in liver cells that helps sustain function during a crisis. The system is powered by methionine, an amino acid found in high levels in egg, meat, fish, Brazil nuts, sesame seeds, and cereal grains.
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A recent study by McGill University researchers has found that ubiquinone, a widely believed antioxidant, is unlikely to provide benefits for cell protection. The study used mice with controlled ubiquinone biosynthesis levels and discovered no signs of oxidative damage despite the loss of the substance.
A higher intake of lycopene among postmenopausal women may lower the risk of renal cell carcinoma by 39%. The study analyzed data from 96,196 women and found a significant association between lycopene intake and reduced kidney cancer risk. Lycopene is a natural antioxidant found in foods like tomatoes and watermelon.
Researchers found that an intermittent feast-and-famine diet increased sirtuin proteins, which promote longevity and protect against age-related diseases. The diet also decreased insulin levels, potentially having an anti-diabetic effect.
New potato varieties 'Entzia' and 'Miren' offer great nutritional value, antioxidant properties, and increased resistance to disease. They are suitable for both culinary and industrial uses, providing benefits such as high carotene content and lower reliance on external varieties.
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Women with multiple sclerosis may have lower levels of important antioxidant and anti-inflammatory nutrients like folate from food and vitamin E compared to healthy people. The study found that women with MS had lower average intake of these nutrients and a lower percentage of calories from fat.
Researchers at the Max Planck Institute for Chemical Ecology discovered that fruit flies can detect antioxidants using olfactory cues, increasing feeding behavior and triggering oviposition. This form of detection is not unique to insects, as humans also perceive pleasant odors from healthy nutrients.
A new technique developed by researchers from the University of Granada has shown that the antioxidant capacity of orange juice is multiplied tenfold compared to traditional analysis methods. This finding suggests that tables on the antioxidant capacities of food products used by dieticians and health authorities must be revised.
Researchers have found that selenium and selenoproteins are at elevated levels in large, healthy ovarian follicles, playing a critical role as an antioxidant during follicle development. This discovery could lead to better understanding of how to optimize selenium levels to improve women's chances of conceiving.
A new study by Montana State University researchers found that extreme weather events can significantly impact the chemical composition of tea. Samples from two extreme weather events revealed a 50% decrease in certain antioxidant compounds and a corresponding drop in household income for tea farmers.
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Scientists have discovered that wild tomato species like Solanum habrochaites and Solanum peruvianum contain higher levels of antioxidants, which can help improve the health-related characteristics of cultivated tomatoes. The study provides valuable insights for breeding programs aiming to enhance antioxidant traits in elite tomato lines.
A recent study on a cooperative bird species found that dominant birds, who work harder and take on more responsibilities, experience weakened antioxidant protection after a breeding season. This suggests that unequal sharing of workloads in societies may leave the hardest-working individuals at risk of poor health and accelerated ageing.
A study found that high-protein enteral nutrition enriched with immune-modulating nutrients does not reduce new infections or improve outcomes in critically ill patients. In fact, it may be harmful, increasing the risk of death at 6 months.
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Research published in Neural Regeneration Research found that atorvastatin, a commonly used lipid-lowering drug, protects against cerebral ischemia/reperfusion injury. The study discovered that atorvastatin's anti-inflammatory and antioxidant effects contribute to its protective benefits.
Northwestern University professor Guillermo Ameer's team created a biodegradable, antioxidant biomaterial that reduces scarring and heals diabetic ulcers. The material is made from citric acid and vitamin C, and has potential applications in tissue engineering, medical device coating, and regenerative medicine.
The study found that melatonin treatment reduced decreased levels of antioxidant vitamins and enzymes in rats with traumatic brain injury, indicating a protective effect on cerebral cortex and blood toxicity. Melatonin also inhibited free radical formation and supported the antioxidant vitamin redox system.
Recent research suggests that antioxidant supplements and foods may not reduce cancer risk, but instead accelerate cancer development. The study proposes that antioxidants accumulate at distant sites in cells, leaving tumor-promoting ROS relatively unperturbed, which can stimulate cancer cell growth.
A study compared phenolic compounds in indigenous rose species to those of modern cultivars, revealing distinct differences in leaf phenolic content. Indigenous rose species are found to contain higher levels of phenolic antioxidants, making them a potentially suitable source for medicinal purposes.
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Researchers discovered uric acid's role as a major intracellular antioxidant that prevents oxidative stress and its impact on cancer and aging. The p53-GLUT9 pathway is a mechanism to prevent ROS accumulation, which causes cell damage.
A new study by CU-Boulder reveals that an antioxidant called MitoQ can reverse the negative effects of aging on arteries, improving vascular function and reducing the risk of heart disease. MitoQ targets mitochondria, specific cell structures responsible for oxidative stress, and restores endothelial function in old mice.
Scientists at the University of Arizona have discovered a molecular pathway that could help create new therapies for end-stage liver disease. By understanding how Nrf2 is suppressed in cirrhotic livers, researchers have identified Hrd1 as a key player in exacerbating the disease process.