Researchers developed a compound consisting of insulin bound to an antioxidant group, improving glucose consumption and brain function in mice with type 1 diabetes. The combination therapy showed better cognitive performance than individual treatments alone.
The Texas Tech University Health Sciences Center has received a five-year, $1.87 million NIH grant to investigate the role of vitamin A depletion in Alzheimer's disease. The research aims to test the hypothesis that a lack of antioxidant all-trans retinoic acid (ATRA) promotes reactive oxygen species toxicity.
Researchers from Skoltech identified four genetic markers that can predict tocopherol composition in sunflower lines, which is crucial for producing high-quality dressing and cooking oils. This breakthrough discovery will help facilitate faster breeding of new varieties.
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A recent study found that nutrient levels in broccoli and kale microgreens differ significantly depending on the growing environment. Researchers measured polyphenols and glucosinolates in microgreens grown under different conditions, revealing varying levels of antioxidant- and anticancer-related compounds.
Prunes have been found to help prevent or delay bone loss in postmenopausal women by reducing inflammation and oxidative stress. This is due to their potential to alter the gut microbiome, which can lead to lower levels of pro-inflammatory cytokines and markers of oxidative damage.
Researchers found that prunes' phenolic compounds and dietary fiber content may alter gut microbiome, decreasing inflammatory markers and improving bone turnover. Clinical trials showed promising effects of prune consumption on bone health outcomes in postmenopausal women.
Research by Penn State found that intensive soil tillage can significantly reduce the availability of ergothioneine in crops. Ergothioneine is an amino acid produced by certain fungi and bacteria, which has potent antioxidant properties and is linked to long-term human health.
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A recent study found that people with Parkinson's Disease who consume more flavonoids have a lower mortality risk than those who don't. The researchers discovered that higher flavonoid intake is associated with improved survival rates in both men and women, particularly when it comes to anthocyanin-rich foods like berries and red wine.
A team of scientists from NTU Singapore has developed a plant-based emulsifier that is rich in protein and antioxidants, allowing it to replace eggs or dairy in food staples. The emulsifier is made by fermenting brewers' spent grain and can help cut down on food waste, reducing greenhouse gas emissions.
Researchers at Washington State University discovered that combining gallic acid with stretching decreases inflammation markers and improves protein production in arthritic cartilage cells. This finding suggests a potential new procedure for treating osteoarthritis by growing healthy cartilage tissue.
Researchers detected emerging synthetic antioxidants in e-waste recycling dust, including hindered phenol and sulfur antioxidants. The study highlights the need for further research on their environmental behaviors and toxicities.
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Scientists discovered an important protective response in the heart that can prevent excessive scarring after a heart attack. The study found that this reactive response can limit cardiac fibrosis by preventing oxidant build-up in heart cells, potentially leading to new therapies to repair scarring damage.
Researchers at Rockefeller University identified SLC25A39 as a transporter protein that brings glutathione, the body's major antioxidant, into cell mitochondria. This discovery opens new avenues for studying oxidative stress and its role in diseases like cancer and neurodegeneration.
Researchers studied bicyclic monoterpene alcohols' fungicidal activity against various fungi, finding (−)-myrtenol to be most promising. The compounds also showed antioxidant and membrane-protective activities, suggesting potential practical applications.
Researchers found an early indicator of Alzheimer's disease is an oxidation-antioxidant imbalance in the blood. Oxidative markers increase up to five years before the onset of the disease, suggesting a potential avenue for prevention through antioxidant intake.
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Researchers have identified a gene that regulates fruit softening independent of fruit ripening, allowing tomatoes to stay firm until consumption while maintaining flavor. The discovery could lead to increased shelf-life without sacrificing flavor, benefiting commercial producers and consumers alike.
A large-scale trial will assess the effects of cocoa supplements and multivitamins on aging, including inflammatory factors and genetic changes. Researchers aim to determine if cocoa consumption can reduce age-related health issues such as heart disease, stroke, and cancer.
Researchers at Ohio State University found that cancer can cause cardiac dysfunction due to the presence of free radicals, which were reversed by specific antioxidants in fruit flies and mice with tumors. The study suggests a potential new approach to treating heart problems in cancer patients.
A new antioxidant drug, cysteamine, has been found to reverse atherosclerosis by reducing the oxidation of LDL cholesterol. This process reduces inflammation, damage, and clot formation, ultimately lowering the risk of heart attacks and strokes. Cysteamine was shown to decrease plaque size by up to 56% in mice with atherosclerosis.
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Researchers found that wood vinegar and tar fraction in bio-oil produced from hazelnut shells pyrolysis at 400 C to 1,000 C contain high concentrations of phenolic substances, which contribute to their antioxidant activity. The study suggests using these fractions as a potential renewable energy source.
Researchers found that eating 50 grams of prunes daily for six months improved CVD risk biomarkers, raised 'good' cholesterol, and lowered inflammation. The study suggests that prunes may be a promising addition to the diet to reduce CVD risk and inflammation.
A study found that adequate levels of five antioxidants may reduce infection with high-risk human papillomavirus (HPV) strains associated with cervical cancer. Lower levels of serum albumin and four dietary antioxidants were linked to a higher risk of HPV infection, suggesting a potential nutritional strategy for prevention.
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Researchers from India and Russia developed edible film technology using sodium alginate and ferulic acid, extending shelf life and preventing oxidation processes. The films can be produced at a low cost and meet food production standards.
Researchers discovered that spraying leaves with high concentrations of ascorbic acid increases protein production three-fold in plants. This simple method can produce valuable pharmaceutical proteins at a lower cost and with increased efficiency.
Space radiation poses significant risks to astronaut cardiovascular health, including myocardial remodeling, atherosclerosis, and inflammation. Research highlights the potential of antioxidant treatments, such as vitamin C and spinach, to protect astronauts from space-induced damage.
Researchers found that different juicing techniques can alter the levels of health-promoting phytochemicals and antioxidants in raw vegetables. Low-speed juicing produced more diverse metabolites, while high-speed centrifugal juicers resulted in thicker juices with less pulp and fiber.
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Antioxidants prevent imaging damage to conducting polymers, allowing for higher-resolution imaging and new insights into polymer structure. This breakthrough enables further development of soft electronic devices.
Researchers at the University of Córdoba have developed new molecules derived from cannabidiol, which induce the expression of heme oxygenase 1 and activate NRF2 to exhibit dual antioxidant activity. This mechanism has great potential for treating skin diseases like atopic dermatitis and epidermolysis bullosa.
Researchers at Kumamoto University developed a new electrochemical system to measure antioxidant capacity in food, eliminating complex separation and extraction steps. This system allows for easy analysis of fat-soluble antioxidants in colorful or cloudy samples without extensive equipment or special treatment.
Researchers at KIST extracted ganoderic acid from Ganoderma lucidum to treat skin conditions like atopic dermatitis. Optimal drying and extraction conditions were found to enhance anti-inflammatory, antioxidant, and anti-diabetic effects.
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A team of researchers has discovered a new mechanism that explains why patients with ocular hypertension do not develop glaucoma. They found increased antioxidant capacity and higher levels of omega-3 fatty acid chemical messengers, providing potential resistance to elevated intraocular pressure.
Researchers developed a simple, low-cost method to synthesize silver nanoparticles using habanero peppers. The process utilizes the antioxidant properties of the peppers to reduce silver ions, resulting in stable nanoparticles with potential applications in optics, biosensing, and antimicrobial coatings.
Researchers create antioxidant-boosted milk chocolate by combining peanut skins and coffee waste with maltodextrin. The resulting confection has higher chemical antioxidant activity than most dark chocolates and is undetectable in flavor.
Researchers from IKBFU Institute of Living Systems studied the protective mechanisms of beach pea plants (Lathyrus maritimus Bigel) on the Curonian Spit. The study found that these plants accumulate low-molecular antioxidants to adapt to extreme conditions, such as high salinity and low temperatures.
Research suggests that people with low selenium levels are at risk of paracetamol overdose even when following dosage guidelines. A lack of selenium can slow down the body's ability to eliminate paracetamol, making it more toxic.
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Researchers developed antioxidant-rich powders from blueberry and persimmon waste, which showed beneficial effects on gut bacterial growth. The findings suggest that these powders could be used to boost carotenoids and anthocyanins in food formulations, potentially promoting human health.
Researchers discovered that flavonoids from a specific corn line reduced inflammation in mice with an inflammatory-bowel-disease-like condition. The study suggests that flavonoid-rich corn may provide protective effects on human health, offering a promising new approach to treating chronic intestinal disease.
Researchers found that birds consuming dietary antioxidants before and during fall migration can reduce their endocrine stress response. This reduction in stress may be a major benefit for birds, allowing them to perform better during long-distance flights.
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A new study found that high uric acid levels protect female lung function from decline with age or disease. Women with lower female hormone levels are more likely to benefit from this antioxidant effect.
Researchers found that death is preceded by accumulation of reactive oxidative species (ROS) in the gut, which can be neutralized to prevent premature death. The study on fruit flies suggests a key role for the gut in causing death from sleep deprivation, and may inform future efforts to address its detrimental effects in humans.
A new model developed by Washington State University researchers allows winemakers to easily test the chemical makeup of their red wine, providing accurate predictions on mouthfeel and color. The model simplifies lengthy tests, enabling technicians and winemakers to get useful results with relatively simple tests.
Researchers at Texas A&M University have created mesh-like mats with prolonged antioxidant activity that can be used in bandages or food storage containers. The mats are made from an intertwined network of ultra-fine strands of a polymer and tannic acid, which enhances antioxidant functionality.
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Scientists found that PTSD patients exhibit changes in small blood vessels, leading to abnormal responses in the sympathetic nervous system. Antioxidant supplements can reduce oxidative stress and improve blood vessel function.
Researchers at Kazan Federal University have created a novel amperometric sensor to detect sterically hindered phenols, including synthetic phenolic antioxidants. The sensor uses electropolymerized carminic acid as the sensitive layer and has been successfully tested on linseed oils, confirming high accuracy of antioxidant detection.
Research suggests exercise can prevent or reduce severity of ARDS, a major cause of death in COVID-19 patients. Regular physical activity increases production of antioxidant EcSOD, which may provide protection against severe respiratory disease.
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Researchers from Kumamoto University found that the DsbA-L protein plays a crucial role in maintaining lung function in the elderly. They discovered that variations in the DsbA-L gene are associated with changes in respiratory function and antioxidant functionality. The study suggests that boosting DsbA-L expression may help promote he...
A new NIH study found that antioxidant supplements did not improve semen quality or pregnancy and live birth rates in men with infertility. The Males, Antioxidants, and Infertility Trial (MOXI) reported no statistically significant differences between the placebo and antioxidant groups.
Researchers simulated cooking conditions in a domestic kitchen to assess the degradation of antioxidants in extra virgin olive oil. The results show that cooking time and temperature affect the polyphenol content, with antioxidant levels decreasing by 40% to 120ºC and 75% at 170ºC.
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Researchers have discovered a molecular pathway that, when silenced, restores immune cells' normal function in people with fatty liver disease. Silencing a microRNA molecule called miR144 increases the endogenous antioxidant response, suggesting a promising therapeutic strategy for treating non-alcoholic steatohepatitis.
Researchers have found that natural antioxidant L-ergothioneine can relieve some clinical symptoms of Pre-eclampsia in rats, including reduced blood pressure and fetal growth restriction. Further study is needed to validate its safety and efficacy in humans.
A study published in Genetics found that Coenzyme Q10 reversed most of the reproductive harms caused by exposure to BPA in Caenorhabditis elegans worms. The antioxidant improved or reversed multiple types of damage, including lower rates of egg cell death and fewer chromosome abnormalities.
Researchers have found a possible link between a genetic variation and atrial fibrillation in zebrafish, suggesting a structural defect in the heart muscle and mitochondria. Early treatment with antioxidants may prevent the disorder in fish, but more research is needed to understand its human implications.
A recent study published in Scientific Reports found that simple leaf wounding in plants can increase the production of healthier organic fruit. The research team discovered that stress responses created in the fruits and vegetables lead to an increase in antioxidant compounds prior to harvest, making them healthier for human consumption.
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IKBFU researchers have found that alder bark extracts contain high levels of polyphenols and antiradical activity, offering potential benefits for anti-aging and disease prevention. The study also reveals the presence of oregonin, a diarylheptanoid glycoside with anti-inflammatory and antimycotic properties.
A new survey confirms that muscadine grapes are susceptible to parasitic nematodes, which can impact yield and grape quality. The study found seven types of nematodes associated with muscadines in Georgia and North Carolina.
Researchers at UTA are developing a groundbreaking treatment to accelerate the healing of cranial injuries using live 3D printing and regenerative antioxidant materials. The approach has the potential to shorten healing time and make treatment more accessible for patients.
Researchers from Trinity College Dublin found that lower levels of specific vitamins and antioxidants are consistently associated with frailty in older adults. The study also suggests that micronutrient insufficiencies may act as an easily modified marker for frailty, offering new potential treatments.
A recent study published in Nutrients found that an inflammatory diet increases the risk of colorectal cancer by almost twice. The researchers suggest adopting a Mediterranean diet rich in fruits, vegetables, nuts, whole grains, and healthy oils to reduce the risk of colon cancer.
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A study found grasshoppers and silkworms have antioxidant capacity similar to fresh orange juice, while crickets offer 75% the same antioxidant power. Insects are a sustainable alternative to meat and animal products, with minimal land, water, and carbon footprint.
Research found that superoxide dismutase improves cognition by fighting oxidative damage but loses effectiveness when tau proteins increase, suggesting a losing battle against Alzheimer's disease. Increasing SOD1 production may delay progression of the disease, according to Iowa State University researchers.