Articles tagged with Antioxidants
Researchers from Shinshu University have identified Inaoside A, a new antioxidant phenolic compound derived from the edible mushroom Laetiporus cremeiporus. The compound exhibited significant antioxidant activity, including 80% inhibition of DPPH radical scavenging and an IC50 value of 79.9 μM.
Researchers developed a curcumin nanoemulsion that effectively improved the bioavailability of curcumin and modulated the gut microbiota of mice with intestinal inflammation. The nanoemulsion increased the presence of beneficial bacteria, reducing symptoms of intestinal damage.
Researchers investigated the impact of senolytic treatments on DNA methylation clocks and epigenetic age. Results showed significant increases in epigenetic age acceleration with Dasatinib and Quercetin treatment, but not with Fisetin addition.
The study found that ginseng can significantly reduce post-exercise muscle damage in healthy adults and improve muscle regeneration. Taking ginseng systematically for a long time can also mitigate the response of biological markers responsible for exercise-induced muscle damage and inflammation.
Researchers at Cornell University have developed nanofiber-coated cotton bandages that exhibit excellent antibacterial performance against gram-negative and gram-positive bacterial species. The bandages, infused with lawsone, a red-orange compound found in henna leaves, also show antioxidant and anti-inflammatory properties.
Researchers found that artepillin C interacts intensely with tumor cells, altering their fluidity and triggering autophagy. The study's results contribute to a deeper understanding of the substance's action mechanisms and provide insights for future research.
The project will assess how xanthophyll carotenoids in NutraMaize Orange Corn mitigate negative health effects associated with heat-induced oxidative stress. The researchers aim to improve egg-laying hen health and performance during heat stress events.
Researchers discovered that Nectandrin B, a bioactive lignan compound from nutmeg, extends the lifespan of Drosophila melanogaster by as much as 42.6%. The study found that Nectandrin B reduces intracellular ROS levels and improves age-related symptoms such as locomotive deterioration and neurodegeneration.
Research published in The FASEB Journal suggests that spaceflight can negatively affect vascular tissues, increasing the risk of erectile dysfunction. Treatment with antioxidants may help counter some effects. Functional improvements after targeted interventions suggest that erectile dysfunction may be treatable.
Researchers found that quercetin in red wine can cause headaches due to its interference with alcohol metabolism, leading to high levels of acetaldehyde. The study suggests a new hypothesis for why some people experience red wine headaches, particularly those with pre-existing migraine or primary headache conditions.
Researchers identify protein SLC25A39 as a double-functioned nutrient sensor and transporter for mitochondria, regulating glutathione levels to prevent oxidative stress. The discovery sheds light on the critical role of glutathione in maintaining mitochondrial function.
Researchers at Texas A&M University have found a correlation between flavonoid compounds and reduced endometriosis symptoms. Flavonoids like Quercetin and Kaempferol show promise in easing inflammation, with studies suggesting they may help suppress the symptoms of inflammatory diseases like endometriosis.
A recent human study found that grape consumption improved key markers of eye health in older adults, including increased Macular Pigment Optical Density (MPOD) and reduced AGEs. Regular grape intake was also shown to increase plasma antioxidant capacity and total phenolic content.
Researchers at the University of North Carolina at Greensboro found that teff increases levels of glutathione, an antioxidant molecule, and gene expression related to glutathione pathways. The study used human leukemia monocytic cells and compared ivory and brown varieties of tef, with brown teff producing higher glutathione levels.
Researchers found that antioxidants activate a mechanism forming new blood vessels in tumor cells, which can help them grow and spread. The study suggests that dietary supplements containing antioxidants may accelerate tumour growth and metastasis in cancer patients.
A University of Illinois study found unique Mexican black and pinto bean varieties to be high in phenolic compounds and anthocyanins, which have antioxidant and anti-inflammatory properties. The research also identified potential applications for the seed coat extracts in the food industry and cosmetics.
Researchers at Istituto Italiano di Tecnologia and University of Milan-Bicocca have demonstrated the efficacy of curcumin in reducing coral bleaching caused by climate change. The study shows significant efficacy in preventing coral bleaching when tested under controlled conditions.
Researchers at Buck Institute for Research on Aging developed a bioavailable compound that selectively inhibits free radical production in mitochondria, preventing and treating metabolic syndrome in mice. The compound, S1QEL1.719, decreases fat accumulation, improves glucose tolerance, and normalizes fasting insulin levels.
A daily dose of 500 mg propolis improved immunity, reduced free radicals, and attenuated chronic inflammation in asymptomatic HIV patients. The study showed a significant reduction in plasma levels of malondialdehyde and an increase in total antioxidant capacity.
A new drug delivery method utilizes polymer-stabilized crystals to deliver antioxidants to stem cells, minimizing variation in drug release and extending the duration of effectiveness. This technology can be applied to various cell cultures and potentially other hydrophilic drugs, disease models, and methods applications.
The study investigates the effects of DPDT on human colon cancer HCT116 cells and non-tumorigenic MRC5 fibroblasts. The results show that DPDT preferentially targets HCT116 cells, inducing apoptosis and G2/M cell cycle arrest, likely through DNA topoisomerase I poisoning.
Researchers have developed methods to produce polyphenolic compounds with improved solubility through microbial fermentation, enabling potential life-saving drugs. The process, called glycosylation, attaches sugar molecules to the compounds, making them more effective in preventing diseases such as cancer and heart disease.
The nucleus is metabolically active and uses antioxidant enzymes to repair DNA damage. Cells relocate mitochondrial machinery to the nucleus in response to DNA damage, highlighting a paradigm shift in cellular biology.
A new study published by LSU Health New Orleans found that a diet high in fruits, dark-green vegetables, and beans can significantly lower the risk of genital high-risk-HPV infection, which is associated with cervical cancer. The research also showed that women who eat healthily tend to practice other healthy behaviors.
Recent research at Mississippi State University has discovered melatonin's various health benefits for cattle, including antioxidant properties that alleviate oxidative stress and potentially controlling body temperature. The hormone also alters the microbiome and promotes skeletal muscle growth in cattle.
A research team at Hokkaido University has developed a system to deliver antioxidants to mitochondria in the liver, reducing oxidative stress and damaging caused by ROS. The system, called CoQ10-MITO-Porter, was found to be more effective when downsized particles were used.
Researchers found that only four products increased lutein liberation in spinach smoothies, with cow's milk and coconut milk showing the most improvement. Plant-based drinks like soymilk had a negative effect on lutein content.
A study found that adding rosmarinic acid to sunscreen increases sun protection factor by over 41% and reduces the need for synthetic chemicals. The natural antioxidant also provides anti-aging benefits, making it a potential multifunctional compound for improved skin health.
Researchers have developed a novel technology for nanoencapsulation of bioactive compounds, specifically anthocyanin, using pectin and lysozyme. The methodology ensures slow release of the compound, allowing it to survive gut bacteria and digestive enzymes.
A recent study found that the mitochondrial antioxidant MitoQ can reverse the detrimental effects of HIV and antiretroviral therapy on organs such as the brain, heart, and liver. The researchers used humanized mice infected with HIV and treated them with MitoQ for three months.
Researchers at Anglia Ruskin University found that consuming a hydroxytyrosol-rich, olive-derived phytocomplex improved respiratory parameters, oxygen consumption, and running economy during aerobic exercise. The study also showed reduced perceived exertion and enhanced acute recovery.
Researchers developed a new muffin recipe using Hibiscus sabdariffa extract, which provides high levels of antioxidants like phenolics. The muffins also have improved nutrition, containing less sugar, saturated fat, and white flour, making them a healthier option.
The study found that phenolic extracts from roselle inhibited fat cell formation by 95%, while hydroxycitric acid had no effect. Researchers hope the plant's antioxidants can be used in health food products to manage obesity without side effects.
A new UNCG study confirms that SARS-CoV-2 destroys the antioxidant activity of key human selenoproteins, weakening immunity and enabling virus replication. The findings suggest investigating selenium supplementation and dietary sulfur compounds as potential symptomatic treatments for COVID patients.
Research suggests that oleic acid in olive oil has antioxidant properties, inhibiting the expression of proteins associated with cholesterol transport, and reducing atherosclerosis. Additionally, oleic acid is recognized as an anti-cancer molecule, which also displays hypocholesterolaemic effects and may influence epigenetic mechanisms.
The addition of antioxidants to cell cultures can improve the production of monoclonal antibodies by reducing oxidative stress and increasing cell viability. This has potential benefits for therapies targeting cancer and autoimmune diseases.
Researchers have developed a new gluten-free flour made from orange sweet potatoes that is rich in antioxidants and has potential uses in fermented products and baked goods. The team found that grinding the flour at different temperatures and methods produced distinct properties, with single-grind flours ideal for breads and double-gri...
Researchers at KTH Royal Institute of Technology have developed a process to unlock soluble ferulic acid-rich dietary fibers from corn bran, a low-value sidestream. The extracted antioxidants can prevent cell oxidation and improve gut health by delivering hydrogels that counteract oxidative stress.
Researchers at Northwestern University developed a sustainable biorefinery that turns organic waste, including lignin, into valuable products. The process involves a microbial electrolysis cell that breaks down lignin into aromatic compounds with medicinal properties.
Researchers discovered that mitochondria actively transport coenzyme Q to the cell surface to protect cells from cell death. The transport process is crucial for regulating coenzyme Q distribution within the cell.
A new study from the University of Copenhagen suggests that combining proteins and antioxidants in foods like coffee with milk may have an anti-inflammatory effect in humans. The researchers found that immune cells treated with this combination were twice as effective at fighting inflammation as those with only polyphenols.
Research reveals that monarch butterflies storing plant toxins experience reduced warning signal conspicuousness due to oxidative stress. The study found a positive correlation between toxin levels and oxidative damage in the butterflies' bodies.
A meta-analysis of over 884 studies found that certain micronutrients can benefit cardiovascular health, including omega-3 fatty acids, folic acid, and CoQ10. These supplements have been shown to reduce the risk of cardiovascular disease, stroke, and mortality.
A recent human study published in Antioxidants found that consuming grapes protected against ultraviolet (UV) damage to the skin. The study showed increased resistance to sunburn and unique microbiomic and metabolomic profiles in subjects who consumed whole grape powder, suggesting a correlation between the gut and skin.
A recent study found that individuals with higher intake of flavonols, found in fruits, vegetables, tea, and wine, experienced slower rates of cognitive decline. The study's authors suggest that the antioxidant properties of flavonols may contribute to this effect.
Researchers have discovered a high-antioxidant ingredient in passion fruit peels that can preserve fresh fruits and cuts in an edible coating, reducing spoilage and plastic packaging. The microencapsulated powders are stable, non-hygroscopic, and suitable for industrial applications.
A study found that higher levels of glutathione in the nucleus accumbens correlate with better performance in motivation tasks. Nutritional interventions targeting GSH levels may improve motivation by modifying behavior and facilitating effortful endurance.
A recent study by University of the West of Scotland found that citrus honey has significantly higher antioxidant activity than other types of floral honey. The research discovered compounds such as hesperetin, linalool, and caffeic acid in citrus honey, which are linked to its enhanced antioxidant properties.
A systematic review and meta-analysis of 19 cohort studies involving over 1 million adults found that moderate tea consumption is associated with a lower risk of developing type 2 diabetes. Drinking at least four cups of tea a day may reduce the risk by 17%.
Scientists discover that methotrexate causes oxidative damage to the cerebrospinal fluid and choroid plexus, leading to cognitive impairment. Adding antioxidants to the CSF may protect against this damage, offering a potential treatment for 'chemo brain'. Researchers are exploring other chemotherapy drugs and testing antioxidant treatm...
Researchers found that incorporating banana peel flour into sugar cookie batter makes the treats more healthful. The addition of banana peel flour resulted in cookies having less fat and protein, higher amounts of phenols, and better antioxidant activities compared to conventional cookies.
Recent studies show that grape consumption can reduce fatty liver and extend lifespans, with Dr. John Pezzuto's team finding changes in genetic expression and antioxidant genes in mice. Adding grapes to a high-fat diet also had positive effects on behavior and cognition.
Researchers found 560 proteins were differentially expressed, with 32 significantly altered, in reductive stress hearts. The proteome signature revealed oxidative stress-related pathways and mitochondrial dysfunction.
International researchers, led by UMass Amherst, discovered a mechanism that allows certain fungi to destroy grapevines using small compounds that reduce iron and produce hydrogen peroxide. Antioxidants and chelators can potentially interrupt this process and prevent grapevine damage.
Researchers at Tokyo University of Science have developed a fast and facile synthesis method for antibacterial amino acid Schiff base copper complexes using microwave irradiation. The new technique produces high-purity products with promising antimicrobial activity, overcoming the challenge of long synthesis times.
A study published in Journal of Pharmaceutical Analysis found that the quality of mistletoe, a traditional Chinese medicine, is affected by its host plant. The researchers used metabolomics to investigate the influence of host plants and environmental factors on mistletoe's medicinal qualities. The results show that both host plants an...
The 24th International Conference on Oxidative Stress Reduction, Redox Homeostasis & Antioxidants, shed light on the latest redox field innovations and the future of redox medicine. Keynote speaker Prof. Helmut Sies discussed stringently selective modulation of enzymatic oxidant sources and sinks in redox nanomedicine.
A new report confirms the benefits of supplements containing lutein and zeaxanthin for slowing age-related macular degeneration progression. The AREDS2 study found that these supplements reduced the risk of AMD progression by 26% compared to the original formula, which contained beta-carotene.
A randomized controlled trial found that consuming cranberries for 12 weeks improved participants' memory of everyday events and neural functioning. The study also showed a significant decrease in LDL or 'bad' cholesterol levels, contributing to improved vascular health and brain perfusion.
Researchers at the University of São Paulo developed a natural antioxidant from unripe acerola, replacing banned synthetic additive TBHQ. The antioxidant microparticles were found to be effective in a range of applications, including food products and cosmetics, without affecting color, flavor or odor.