Articles tagged with Antioxidants
Researchers engineered E. coli microbes to produce the UV-protective compound gadusol, increasing yield by nearly 93 times and showing promise in antioxidant tests. The compound may become an attractive ingredient for sunscreens and skin-care products, offering a greener alternative to traditional ingredients.
A recent study found that lycopene protects porcine intestinal epithelial cells from DON-induced damage by inhibiting PGAM5-mediated mitophagy-dependent ferroptosis. Lycopene increases tight junction proteins, reduces ROS levels, and stabilizes mitochondrial function, restoring barrier integrity.
Researchers found that combining fermented and unfermented cocoa beans can balance flavor and nutritional value, increasing the market potential of Amazonian cocoa. The study also identified new molecules with antioxidant properties, suggesting Amazonian cocoa as a superfood
Researchers at Flinders University developed a high-performance coating made from peppermint essential oil that protects against infection, inflammation, and oxidative stress. The coating demonstrates strong antibacterial action against key pathogens, including E. coli and Pseudomonas aeruginosa.
A new Texas A&M University study found that high doses of antioxidants can negatively influence sperm DNA and lead to craniofacial development differences in offspring. Men should exercise caution when consuming antioxidant supplements if they're planning to have children soon.
A recent review of bamboo consumption found promising health benefits, including improved metabolic health, reduced inflammation, and antioxidant activity. However, caution is advised due to potential risks associated with raw or improperly prepared bamboo.
Research identifies Luohan Guo's terpenoids, flavonoids, and amino acids as key compounds affecting health. The study's findings provide insights into the potential antioxidant mechanisms of monkfruit's active ingredients.
A randomized controlled trial found that lipoic acid had a small beneficial effect on slowing brain atrophy in people with progressive multiple sclerosis. However, it did not improve walking speed as the primary clinical outcome. The study suggests that lipoic acid may be worth further investigation for its potential benefits.
Researchers at Chiba University developed a novel isotope-based method to detect and identify selenium-containing compounds, revealing new biological roles of selenium. The technique uses multiple isotopic signatures simultaneously, reducing errors and improving detection reliability.
A study found that lignin, a polymer from plant cell walls, can improve the performance of nanoparticles with herbicide. Lignin was subjected to a green process and showed distinct properties, making it suitable for customizing different applications. The substance demonstrated potential for sustainable agricultural pest management.
A bioactive compound produced by Bacillus licheniformis has antioxidant, emulsifying, and stabilizing properties. Its exopolysaccharide production is beneficial for producing biodegradable materials, and its functional properties surpass those of commercial xanthan gum.
Research by University of Pittsburgh scientists discovered that damaging telomeres can lead to dysfunctional T cell function. To combat this, they developed a targeted antioxidant approach that rescued T cell function, opening the door for novel therapies in cancer immunotherapies.
Researchers have reimagined hemoglobin as an antioxidant protein in the brain, where it breaks down harmful reactive oxygen species. A new compound, KDS12025, selectively enhances this natural defense mechanism to protect against ALS, Parkinson's, Alzheimer's, and autoimmune disorders.
Researchers at the University of Pennsylvania designed a new recipe for mRNA vaccines by adding phenol groups, which reduce inflammation and improve vaccine effectiveness. The modified lipids improved vaccine performance in various diseases, including COVID-19, cancer, and genetic diseases, with enhanced efficacy and reduced side effects.
Fermenting legume pulses increases their antioxidant activity by up to 83% and their capacity to regulate Type 2 diabetes markers by up to 70%, according to a study. Red lentil and green split pea exhibited the greatest improvements in antioxidant scavenging activity and protein solubility.
A new edible biofilm developed by Brazilian researchers extends the shelf life of strawberries by up to 11% while preserving their freshness, taste, and aroma. The film, made from pomegranate peel extract and natural polymers, acts as a barrier to microorganisms, moisture loss, and gas exchange.
Filipino researchers found a way to enhance tapuy lees for high polyphenol content and antioxidant activity, extending test animal lifespan and health. The study suggests repurposing tapuy lees as a health food to combat aging and oxidative stress-related diseases.
Researchers developed synbiotic chocolates fortified with probiotics and prebiotics, showing improved gut microbiome balance and probiotic survival rates. The study found that the orange-flavored chocolates had a softer texture and more luxurious bite experience.
Researchers at Scripps Research have synthesized a stable form of carnosic acid, which showed enhanced memory and synaptic density in mouse models of Alzheimer’s disease. The compound also decreased inflammation in the brain, offering potential as an anti-inflammatory drug for treating cognitive decline.
Researchers developed gene-edited lettuce with significantly higher levels of β-carotene, zeaxanthin, and ascorbic acid without compromising plant growth. This breakthrough highlights the potential of gene editing to combat micronutrient deficiencies and improve dietary quality.
A recent study by Edith Cowan University found that spraying persimmon trees with methyl jasmonate (MeJA) results in healthier, longer-lasting fruit with increased antioxidants. The application of MeJA also enhances fruit colour and improves phytochemical quality.
The review explores how antioxidant-enzyme interactions contribute to the development of non-communicable diseases, including cardiovascular disorders and cancer. Emerging therapeutic strategies harness these interactions to manage NCDs, offering potential benefits through dietary and pharmacological interventions.
This study found that intermediate-term oral contraceptive use was associated with lower antioxidant levels and higher triglyceride and low-density lipoprotein levels. Regular monitoring of these parameters is recommended for OCP users to mitigate potential metabolic and hepatic effects.
Researchers at Nagoya University found that luteolin, an antioxidant in vegetables, can suppress hair graying by preserving endothelins and supporting healthy melanocyte activity. The study suggests luteolin's unique medicinal effect may be a promising candidate for addressing age-related hair graying.
Researchers from Osaka University found that selenoproteins are essential for counteracting lipid peroxides and maintaining hematopoiesis in human cells. The study also showed that dietary Vitamin E can protect hematopoiesis and repair impaired B cell differentiation, providing potential strategies for fighting age-related diseases.
A systematic review of 24 studies suggests resveratrol can enhance the quantity and quality of egg cells, called oocytes. The compound may also treat infertility related to endometriosis and obesity.
The addition of jabuticaba peel flour increased the bread's fiber content by over 50% and raised its antioxidant capacity by 1.35-3.53 times, leading to improved blood sugar control and insulin response. The study found that satiety increased after consuming the bread with jabuticaba peel flour, suggesting a lower glycemic index.
Researchers found a powerful antioxidant in Deinococcus radiodurans that combines with manganese to protect against radiation damage. The discovery could lead to synthetic antioxidants tailored for human needs, protecting astronauts and preparing for radiation emergencies.
Researchers isolated three purified polysaccharide fractions from sea buckthorn and found them to have good thermal stability, antioxidant activity, and reducing capabilities. The polysaccharides outperformed vitamin C in eliminating free radicals, making them promising for application in functional cosmetics.
The study presents a lignin-based hydrogel that combines mechanical strength with bioactivity, promoting wound healing and sustained drug release. The hydrogel's controlled-release properties make it an ideal candidate for treating complex wounds and reducing medication side effects.
A team of Kobe University bioengineers successfully produced artepillin C in bioengineered yeast, achieving ten times the previous yield. The production process involved carefully tuning key steps along the molecular production line, and further improvements are being explored to increase efficiency.
This study explores the radioprotective effects of Licochalcone B on radiation-induced cell damage and mortality in mice. Lico B significantly improves antioxidant levels, reduces DNA damage, and lowers inflammatory factors.
Researchers developed a lignin sub-microsphere loaded with TiO2 for enhanced sunscreen capabilities, achieving SPF 42.93 and improved color properties.
A study found increased antioxidant content and activity in Japanese apricot pickles made with salted red perilla leaves. The phenolic compounds' release was highest before digestion, but a significant increase occurred between 60 minutes and 120 minutes of small intestinal digestion.
Four plants eaten by western lowland gorillas in Gabon, also used by local traditional healers, show antibacterial and antioxidant properties. Researchers identify four plant species with promising targets for treating multidrug-resistant infections.
Researchers have identified compounds from fish gut bacteria that inhibit tyrosinase and collagenase enzymes, making them potential ingredients for skin care products. The findings suggest that the gut microbes of red seabream and blackhead seabream may produce promising anti-wrinkle and skin-brightening agents.
Researchers validate increase of specific t-Cys sites associated with aging in human proteome, suggesting potential role in age-related diseases. The study expands beyond classical proteinopathic paradigms, highlighting trioxidized cysteine as a key molecular mechanism underlying aging.
New research compares four methods for extracting edible insect protein, finding that alkali extraction boosts protein content while enzyme treatment improves nutritional value. Additionally, salt-assisted extraction reveals anti-inflammatory effects and anti-diabetic properties.
Recent studies highlight the vital role of fruits, vegetables, and co-products in preventing chronic diseases. A diet rich in these foods can lower blood pressure, reduce heart disease risk, and improve overall health.
Researchers at Osaka Metropolitan University found that Ecklonia cava polyphenols can protect against neurodegeneration and improve motor function in Parkinson's disease model mice. The antioxidants activate the AMPK enzyme and inhibit reactive oxygen species production, reducing neuronal cell death.
Researchers at UC San Francisco found a link between healthy diets and a younger biological age. Even when people eat healthy diets, each gram of added sugar is associated with an increase in epigenetic age. The Mediterranean diet had the strongest association with lower epigenetic age.
Researchers found that taking AREDS2 supplements slows the expansion of geographic atrophy regions towards the central foveal region of the retina. The study suggests that antioxidant supplementation may slow central vision loss in people with late-stage dry AMD, supporting continued use of AREDS2 supplements.
Researchers found increased liver oxidative stress and impaired antioxidant defenses in a DS murine model. The study suggests potential therapeutic strategies targeting oxidative stress and lipid metabolism to prevent or mitigate liver-related complications.
Researchers have identified two highly soluble molecules with superior antioxidant benefits for cells, which could help prevent and manage certain degenerative diseases by maintaining lower levels of harmful free radicals. The study suggests that these molecules can transfer and accumulate in membranes, reducing the risk of cell damage.
Researchers at UNICAMP and UCA optimize anthocyanin extraction from jabuticaba peel, achieving a higher yield than traditional methods. The novel method uses biosorbent material derived from the residue, resulting in an efficient and environmentally friendly process.
Essential oils have been shown to possess significant bioactive components with therapeutic potential, influencing various industries such as food, cosmetics, and pharmaceuticals. Their antioxidant, antimicrobial, and anti-inflammatory properties make them valuable in managing diseases like cancer, Alzheimer's, and diabetes.
Weo electrolyzed water (WEW) has been shown to attenuate cellular senescence in both normal fibroblasts and breast cancer cells. The study found that WEW modulated markers of cellular senescence, inflammation, and stress response genes in a cell type-dependent manner.
Research suggests that oxidative stress (OS) may trigger Alzheimer's disease and that enriching brain glutathione (GSH) could be a way forward. Clinical studies indicate GSH depletion in the hippocampus initiates early onset of AD prior to amyloid beta deposition and tau phosphorylation.
Twendee X reduces oxidative stress, improves skin and lung health, and suppresses fibrosis in SSc mouse models. The supplement's antioxidant effects are likely more potent than individual compounds alone.
Researchers at Osaka Metropolitan University discovered that persimmon tannin improves the growth of Saccharomyces cerevisiae in the presence of ethanol. The antioxidant properties of persimmon tannin limit oxidative damage, allowing yeast to thrive and increasing bioethanol production efficiency by 8.9-fold.
Fermenting blueberry juice creates a wine that maintains fruit benefits, but temperature and time influence nutrient content. The study found anthocyanin and flavanol levels decreased, while flavan-3-ol increased with longer fermentation times.
Researchers found that geraniol reduces oxidative stress and neuroinflammation-mediated cognitive impairment in a mouse aging model. Geraniol treatment improved spatial learning and memory by enhancing anti-oxidant and anti-inflammatory effects.
Researchers from NTU Singapore have created a method to extract over 80% of the available protein in grain leftovers from brewing beer, commonly known as brewers' spent grain. The extracted proteins could be used commercially to enrich human diets and cosmetic products, providing an eco-friendly alternative to conventional ingredients.
Long-term treatment with methylene blue (MB) and mitoquinone (MitoQ) did not alter age-related bone loss in mice. Antioxidant interventions are insufficient to inhibit skeletal aging, suggesting alternative approaches may be needed.
A blended antioxidant supplement improved spatial learning ability and short-term memory in supplement-treated aged mice. The discovery suggests that the supplements may also prevent age-related cognitive decline in humans and mitigate muscle frailty.
Researchers have identified the unique nutritional profile of Canadian sea buckthorn berries, which are rich in polyphenols with potential health benefits for cardiovascular protection and anti-inflammatory properties. The study found that geographical factors influence the polyphenolic profile of the berries, making them a promising s...
Researchers found that daily cranberry extract consumption for 28 days improved running speeds by 1.5% and reduced post-exercise blood lactate levels. The study also showed increased muscle oxygenation rates and slower deoxygenation.
Researchers from Shinshu University have identified Inaoside A, a new antioxidant phenolic compound derived from the edible mushroom Laetiporus cremeiporus. The compound exhibited significant antioxidant activity, including 80% inhibition of DPPH radical scavenging and an IC50 value of 79.9 μM.
Researchers developed a curcumin nanoemulsion that effectively improved the bioavailability of curcumin and modulated the gut microbiota of mice with intestinal inflammation. The nanoemulsion increased the presence of beneficial bacteria, reducing symptoms of intestinal damage.
Researchers investigated the impact of senolytic treatments on DNA methylation clocks and epigenetic age. Results showed significant increases in epigenetic age acceleration with Dasatinib and Quercetin treatment, but not with Fisetin addition.