Articles tagged with Oxidation
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Researchers found that increasing NADPH levels in cells improved natural antioxidant defenses, reducing oxidative damage and age-related processes. Long-lived transgenic animals showed lower levels of oxidative damage and delayed aging, with increased longevity and better movement coordination.
Researchers have discovered that diamonds can form in a simpler natural chemical reaction involving water and rock. This finding could lead to a better understanding of the Earth's deep formation processes.
The new catalyst developed by researchers at Oak Ridge National Laboratory features unprecedented selectivity and a conversion rate nearly twice that of conventional catalysts. This breakthrough enables the selective oxidation of cyclohexane to produce nylon precursor with increased efficiency.
A study led by Indiana University biologist Patricia Foster found that external environmental forces and oxidation are the primary threats to DNA repair, unlike previously thought. The research used whole genome analysis of spontaneous mutation in E. coli and showed that only loss of oxidative damage repair significantly impacted mutat...
Researchers have developed a new catalyst for selective oxidation of methanol to dimethoxymethane, achieving high conversions and selectivities under mild conditions. The optimized catalyst, V2O5/TiO2-Al2O3, exhibits superior performance compared to traditional methods.
Researchers have successfully prevented black phosphorus from oxidizing, allowing for the exploitation of its extraordinary properties in various devices. The study's results, published in Nature Materials, will help develop new nanotechnologies with high-performance microprocessors, lasers, and solar cells.
Researchers found that oxidation in cardiac cells disrupts PKG's ability to shield the heart from stress. Oxidation-resistant forms of PKG, however, allow for better protection against disease.
Researchers have found that people with cystic fibrosis have limited ability to uptake and use oxygen in their muscles, leading to exercise intolerance. The study uses Near Infrared Spectroscopy (NIRS) to evaluate skeletal muscle oxidative capacity in patients with CF, providing a non-invasive method for measuring muscle function.
Researchers at Sandia National Laboratories directly measure hydroperoxyalkyl radicals, a class of reactive molecules controlling early stages of combustion. This breakthrough improves the fidelity of models used by engine manufacturers to create cleaner and more efficient cars and trucks.
A recent mouse study from Johns Hopkins Medicine found that modifying fat cells' metabolism does not result in obesity. The research team discovered that even when fat cells cannot burn fat, mice do not become overweight.
A new study published in PNAS reveals that atomic steps on metal surfaces can slow down oxidation by forcing them to bunch closer together and eventually stopping their growth. This discovery could have significant implications for understanding and controlling oxidation in a wide range of materials.
Researchers discovered that aluminum atoms involved in forming oxide stripes come exclusively from the steps, not the terraces. The growing oxide stripes are confined to the flat terraces and must push the steps away as oxygen continues to grab aluminum atoms from the edges.
Scientists have discovered that hydrogen peroxide is a key regulator of cellular functions, transmitting signals by oxidizing specific proteins. This discovery challenges previous assumptions and opens new avenues for understanding cancer development and progression.
Researchers at UMass Amherst have developed a new type of organic solar cell that can use virtually any metal for the electrode, effectively breaking the 'electrode barrier'. The new design allows for improved electron transport efficiency and reduced work function, making it more efficient and cost-effective.
Gold nanoparticles work as catalysts to speed chemical reactions despite being inert metals. Researchers have now fully understood the role of water in this process, revealing its crucial role as a co-catalyst for transforming carbon monoxide into carbon dioxide.
A prospective study found that baseline levels of fluorescent oxidation products (FlOP_320) predicted the risk of future hip fracture in postmenopausal women. Women with higher FlOP_320 readings had a significantly increased risk of hip fractures, with those in the upper 30% having 2.67 times the risk.
Researchers developed a new optical microscopy technique to analyze the redox state of mitochondria in living tissue. The study revealed that severance of an axon results in a wave of oxidation of the mitochondria, which begins at the site of damage and is propagated along the fiber.
Columbia researchers uncover a chemical reaction that increases muscle protein elasticity in response to stretching forces. This finding could lead to new treatments for muscle disorders like dilated cardiomyopathy.
Research reveals that oxidation reaction between atmospheric iron oxide reduces soil plasticity, sensitivity, and structural yield stress. The transformation is caused by micro-structure remodeling, not inherent mineral changes, and has potential adverse effects on soil stability.
Researchers at NIST developed a new method to accurately measure changes in living cell redox potential, which can serve as an indicator of cellular health and function. The technique uses nuclear magnetic resonance spectroscopy to detect glutathione levels and monitor intracellular redox reactions.
Researchers found that weekend drinking leads to double the oxidative damage compared to non-drinkers, with DNA damage affecting 44% of cells in drinker group. The study reveals a new potential health risk associated with young people's alcohol consumption.
Researchers have discovered an additive that inhibits oxidation in wine, reducing discoloration and loss of aroma. Chelation compounds like phytic acid can bind with metals to neutralize oxidation, making it a promising solution for winemakers.
Scientists have identified promising new materials that can encase uranium-bearing fuel, reducing the risk of high-temperature oxidation and failure. These materials may eventually replace traditional zirconium alloys, which have been used for 50 years, if they prove safer in the event of a nuclear disaster.
The American Chemical Society is hosting a symposium on the health benefits of polyphenols in plant-based foods, including dark chocolate, coffee, and nuts. Researchers will present their findings on the antioxidant properties of polyphenols and their potential role in reducing cardiovascular disease and certain forms of cancer.
Researchers at MIT have elucidated a 37th type of chemical reaction, crucial for understanding climate-affecting aerosols and human physiology. The reaction involves the decomposition of complex organic molecules and has significant implications for combustion reactions in engines.
Researchers discover manganese(III) forms up to 90% of total manganese present in marine environments with gradation of oxygen concentrations. The finding sheds light on the complex connections between biology, geology and chemistry in ocean environments.
Thioperamide significantly decreases brain water content and malondialdehyde levels while increasing histamine levels and superoxide dismutase activity, preventing oxidative damage and brain edema. Thioperamide's effects are mediated by postsynaptic H1 receptors.
Researchers found that breathing motor vehicle emissions alters high-density lipoprotein (HDL) cholesterol, making it contribute to clogged arteries. The inhalation of emissions activates components of oxidation, leading to inflammation and hardening of the arteries.
Researchers have discovered a protein that turns into a 'cell executioner' when damaged by oxidative stress, opening up new options for treating conditions such as ALS and spinal cord injuries. This modified protein is linked to various health problems, including heart disease, cancer, and aging.
Scientists discovered a reaction site on the perimeter of gold-titanium complex that enables catalysis. The oxide surface plays an important role in modifying the metals above it, leading to the creation of valuable hydrocarbon fuels.
Researchers found that single-wall carbon nanotubes significantly reduced accumulated DNA damage in solutions with nanotubes present. The protective effect was attributed to the nanotubes acting as scavengers, binding up oxidative species and preventing them from interacting with DNA.
Researchers developed an agent that blocks cardiolipin oxidation, preventing cell death and preserving function in rats with severe traumatic brain injury. The study suggests a targeted oxidation-blocker may also be beneficial in treating other neurological disorders such as Parkinson's disease and stroke.
Researchers from Sandia, Manchester, and Bristol have made direct measurements of a gas-phase Criegee intermediate using photoionization mass spectrometry. The study provides new insight into the reactivity of these transient molecules, which are implicated in autoignition chemistry and atmospheric reactants.
A study published in Free Radical Biology and Medicine suggests that grapes can provide more antioxidant protection for the eyes than lutein, a common supplement. Grapes were found to offer dramatic protection against oxidative damage of the retina and prevent blindness in mice consuming them.
Researchers from the University of Granada found that oleic acid and hydroxytyrosol in virgin olive oil, and n-3 polyunsaturated fatty acids in fish, can prevent or mitigate acute pancreatitis. The Mediterranean diet has been recognized by UNESCO as Intangible Cultural Heritage.
Researchers at Rensselaer Polytechnic Institute have recreated ancient minerals to reveal the earliest atmospheric conditions on Earth, challenging years of research on life's origins. The findings suggest an atmosphere dominated by water, carbon dioxide, and sulfur dioxide, rather than methane-filled wasteland.
Rice University researchers developed a method to rapidly convert glucose into biofuels and petrochemical substitutes by reversing the beta oxidation cycle in bacteria. They produced butanol, a biofuel, about 10 times faster than previously reported organisms, using cheap feedstocks like glucose and mineral salts.
Dr. Shapira's research shows that eggs laid by hens with healthier feed can lessen oxidation of LDL cholesterol, potentially reducing heart disease risk. However, these 'healthier' eggs are not widely produced and may be more expensive due to specialized chicken feed.
Guangwen Zhou, a Binghamton University mechanical engineer, has received the National Science Foundation's Faculty Early Career Development (CAREER) Award for his work on oxidation and reduction reactions. His research could lead to more durable gadgets and 'greener' electronics-manufacturing processes.
Researchers found that graphene oxide's solubility is not as expected, with most oxygen content being loosely bound and easily removable by a wash with base. The study reveals that models for graphene oxide structure need revisiting, affecting synthesis and application of chemically modified graphene.
Researchers at Jena University have identified oxylipins in moss that repel snails, a common garden enemy. The study's findings suggest a new organic repellent could be developed using these compounds, offering an eco-friendly alternative to existing pest control methods.
A team of researchers, led by Dr. Peter Sunderland, has created a double-flame burner to improve our understanding of soot formation and oxidation. This innovation aims to design cleaner and more efficient engines that reduce pollution and harm lung diseases.
Researchers at North Carolina State University found that the size of nickel nanoparticles plays a crucial role in determining their structure. Smaller particles form a single void, while larger particles create multiple bubbles, leading to hollow structures with potential applications in energy production and nanoelectronics.
Researchers at the Gladstone Institutes discovered that SIRT3 plays a crucial role in regulating fatty acid oxidation and identified it as a potential therapeutic target. Mice lacking SIRT3 exhibited impaired fat burning and increased levels of fat and triglycerides, highlighting the enzyme's importance in energy metabolism.
A new study found that elevated dissolved oxygen concentrations in alcoholic drinks can accelerate the metabolism and elimination of alcohol. This could provide clinical significance by allowing individuals to become sober faster, reducing acetaldehyde's side effects, and potentially decreasing alcohol-related accidents.
A Purdue University scientist has developed a nanoparticle that protects oils in food products from oxidation, which causes spoilage and degradation. The nanoparticle, modified phytoglycogen octenyl succinate (PG-OS), doubles the shelf life of oil droplets by acting as an emulsifier and barrier to oxidation.
Biomethylation of arsenic compounds causes oxidative DNA damage, enhancing their toxicity and potentially carcinogenicity. Methylation-competent cells exhibited rapid cancer cell acquisition after peak oxidative DNA damage.
Scientists at VIB have identified a bacterial defense mechanism that repairs damaged proteins caused by oxygen. The discovery, using the intestinal bacterium E. coli, has implications for human cells and may provide new insights into protein protection against oxidation.
Migration '09 conference presents new approaches to imaging mineral-water interfaces and controlling actinide migration. Researchers discuss stabilization of intermediate uranium oxidation states and manipulation of plutonium colloids to control its movement.
A small molecule called DAz-2 helps identify over 190 proteins involved in diverse biological processes affected by reactive oxygen species (ROS). The tool will aid in understanding chronic oxidative stress and its role in diseases.
A new probe identifies over 190 proteins that undergo oxidation due to ROS, offering insights into disease processes and potential targets for treatments. The discovery may lead to strategies for fighting diseases involving excessive oxidation reactions.
Researchers at Boston University School of Medicine found that short elevations in circulating nitrite levels can exert lasting beneficial effects on the heart by modulating its oxidation status and protein machinery. This study provides insight into how nitrite can protect the heart from stress and damage.
The National Institute of Standards and Technology (NIST) has developed a new method to accelerate stability testing of biodiesel fuel made from soybeans. The 'advanced distillation curve' method identifies additives that enhance stability at high temperatures, which can cause biodiesel to break down.
Researchers suggest that melanin-based signals in animals may signal their capacity to fight off free radicals and oxidative damage. The study found that reducing glutathione levels increased the size of black stripes in birds' feathers, indicating a link between antioxidant resources and signaling costs.
Research found that chronic severe hepatitis B patients had significantly lower glucose oxidation rates and higher fat oxidation rates compared to acute hepatitis and cirrhosis patients. Upon recovery, patients showed improved energy metabolism, with increased glucose oxidation rates and decreased fat oxidation rates.
Researchers used aberration-corrected STEM instruments to visualize individual gold atoms on iron oxide surfaces, discovering that bilayer nanoclusters with 10 gold atoms are most active in CO conversion, achieving up to 100% efficiency
Researchers from Lehigh University and Cardiff University have identified gold nanoparticles triggered by bilayer clusters as responsible for the critical CO oxidation reaction. The discovery could help protect hydrogen fuel cells and firefighters entering burning buildings.
Scientists discover that glutathione peroxidase 4 senses and translates oxidative stress into a distinct signaling pathway leading to cell death, highlighting potential therapeutic targets for mitigating degenerative diseases. This discovery sheds new light on the molecular mechanisms of oxidative stress and its role in cellular damage.
Researchers at Brandeis University have uncovered a molecular switch in the 'nature's blowtorch' enzyme cytochrome P450. The protein chain can change its structure through a 180-degree rotation, allowing for precise control over oxidation reactions.
A new biosensor measures the oxidation state of glutathione, an important protection molecule, to detect cellular stress. The sensor is highly sensitive and precise, allowing researchers to track short-term variations in oxidative processes.