News on open-access publishing and its reach. Covers journal launches, open-access agreements, and research made freely available.
Researchers found that sudden cardiac death (SCD) among colorectal cancer patients decreased overall, but disparities remained based on age, sex, and geographic location. The study highlights the need for tailored heart monitoring and care strategies for cancer patients, particularly in underserved groups.
The Frontiers Science House is a new meeting venue at Davos that connects breakthrough science to government, business executives, and philanthropists. The house will host over 40 sessions on topics such as precision healthcare, planetary restoration, and digital intelligence.
Two Russian scientists' conceptual similarities challenge conventional aging views. Their ideas about hyperfunction and elevation remain relevant to modern research. Golubev explores the historical connections between Dilman and Blagosklonny, highlighting their contributions to aging science.
Researchers at eight German institutions will benefit from the expanded agreement, which removes financial barriers to open access publishing in JMIR's portfolio of over 30 Gold Open Access journals. The partnership demonstrates a commitment to open science and bibliodiversity.
APS Open Science aims to broaden recognition for high-quality physics research across all stages of discovery. The journal will publish diverse research outputs while upholding rigorous review processes and promoting openness, inclusion, and broad participation.
Researchers developed a machine learning tool, SAMP-Score, to identify compounds that induce senescence in p16-positive cancer cells. The tool successfully identified a promising candidate, QM5928, which triggers senescence without killing cancer cells.
The collaboration enhances transparency in scholarly publishing by certifying reviewer contributions and providing rewards. Reviewers can earn redeemable credits for reviews on partner journals, promoting participation and quality in the research community.
A new meta-analysis published in Aging-US found a significant association between hospitalization for infections and the risk of developing dementia. Adults hospitalized with infections were at an increased risk of all-cause dementia, especially after a single infection-related hospitalization, which can speed up cognitive decline.
A new review connects gut microbiome imbalances to obesity, metabolic syndrome, and colorectal cancer, highlighting the potential for diet and microbiome-based treatments. The study also explores racial and socioeconomic disparities in microbiome-related diseases, emphasizing the need for inclusive prevention strategies.
JMIR Publications has joined the International Association of Scientific, Technical and Medical Publishers (STM) to enhance research quality and trust. The publisher is integrating STM's Integrity Hub to prevent paper mills from operating with fake credentials.
Contributions to Entomology is a peer-reviewed, open-access journal indexed in Scopus, reflecting its commitment to quality and accessibility. The journal publishes research on all aspects of entomology, including insect systematics, ecology, and applied entomology.
A new study found that embryo arrest in IVF is more common with advancing maternal age but not directly related to chromosomal abnormalities. The research suggests two independent factors contribute to the number of euploid embryos available for transfer and overall ART success.
Researchers found that bifidobacterium can boost cancer treatment by regulating the immune system, reducing inflammation, and supporting anti-tumor responses. The probiotic also helps detoxify carcinogens and convert food-based substances into cancer-fighting agents, offering a promising natural ally for cancer prevention and treatment.
Researchers found that excess growth hormone disrupts liver metabolism, leading to molecular and cellular patterns similar to those in naturally aged livers. Reducing glycation stress can reverse these negative effects, improving liver health and physical function.
Clinical trial participants are calling for more inclusive and patient-centered cancer research, highlighting the need for transparent designs and improved communication. The authors propose various improvements to trial design and delivery, including expanding eligibility criteria and involving patient advocates in trial design.
Lymphomas develop resistance to targeted therapies through various mechanisms, including loss of target antigens, reactivation of growth pathways, and changes in tumor microenvironment. Researchers explore new treatment approaches, such as dual-target therapies and biomarker-guided therapy, to overcome these challenges.
A new study found that high tyrosine levels are associated with a shorter lifespan in men, while phenylalanine showed no such link. The researchers suggest that dietary adjustments, such as protein restriction, could help reduce tyrosine levels and support healthier aging.
Researchers found that lower LRIG1 expression is linked to more aggressive gliomas, a type of brain tumor. The study suggests that LRIG1 could serve as a useful marker for tumor severity and potentially as a target for future therapies.
JMIR Publications has integrated Signals Manuscript Checks into its publication process, utilizing AI-powered tools to streamline research integrity evaluations. This partnership aims to increase efficiency and quality, ensuring high standards of scientific integrity in published research.
PLOS has launched PLOS Aging and Health and PLOS Ecosystems to address critical challenges in aging research and ecosystems. The new journals aim to promote open science principles, accelerate scientific progress, and support the highest standard of research ethics.
Researchers found that combining L-BAIBA supplementation with voluntary wheel running exercise enhances musculoskeletal properties in middle-aged male mice. The study showed significant improvements in muscle strength, bone density, and reduced bone marrow fat.
Researchers developed green-synthesized cerium oxide nanoparticles that combined cidofovir with nanoceria, enhancing anticancer activity and binding affinity to DNA and RNA. The new compound destroyed over 97% of cancer cells, suggesting a promising candidate for future cancer therapies.
A new gene editing technique, P3a mutagenesis, achieves near 100% success in creating precise DNA mutations. This method simplifies protein engineering, accelerating biomedical research and reducing costs.
A new study found that faster biological aging measured by DNA-based epigenetic clocks is associated with greater cognitive decline and higher risk of mild cognitive impairment in Hispanic/Latino adults. The study highlights the potential of epigenetic clocks to track changes in brain health over time.
A new case report describes the successful treatment of a 37-year-old woman with HER2-positive breast cancer that had spread to the membranes surrounding the brain and spinal cord. Trastuzumab deruxtecan, an antibody-drug conjugate, improved the patient's neurological symptoms and reduced cancer growth.
Taylor & Francis Group has announced the publication of 32 new open access books on key global themes, including children's welfare and AI. Pledge to Open supports the publication of books that are both free to read and free to publish for their authors through library collective action.
A new study found that alpha-synuclein triggers early gene expression changes in a Parkinson's disease model, revealing brain region-specific and systemic transcriptomic alterations. These changes may contribute to disease development and serve as potential biomarkers.
BioOne and the Max Planck Society have signed a 3-year agreement to bring BioOne Complete aggregation to 84 Max Planck Institutes. The partnership supports shared goals of sustainable open access and equitable scholarly communications, with all institutes maintaining reading access to over 230,000 biological sciences articles.
A rare case of a mucinous vulvar cyst was reported, which resembled a benign lipoma and caused lower abdominal and back pain. The cyst was surgically removed and confirmed to be non-malignant. The case underscores the importance of careful clinical examination in reproductive-age women presenting with vulvar masses.
The Frontiers Research Foundation and One Sustainable Health (OSH) Forum are collaborating to strengthen the global science-policy interface for health and climate. The partnership aims to align research with international policy priorities and amplify its influence, ultimately informing decisions at the highest levels.
Cancer Communications, a new journal published through the AAAS Science Partner Journal program, aims to bridge global oncology insights and clinical impact. The journal welcomes submissions on various cancer research topics, including clinical trials, epidemiology, and molecular biology.
Researchers found that TRF1 protein loss led to leaner mice with altered metabolic profiles, including lower LDL cholesterol levels and improved blood sugar regulation. These benefits occurred without any detectable shortening of telomeres.
Researchers found that PAI-1 levels increase with age in both sexes, but only female mice lacking the gene experienced significant protection against age-related muscle and bone loss. Female mice maintained stronger grip strength and greater muscle mass, while showing less cortical bone loss.
A new analysis by Taylor & Francis and DataSeer found that over half of researchers included a Data Availability Statement in their journal articles, while a third openly shared their data. The study suggests that factors beyond policy mandates are driving the adoption of open research practices.
A rare case of pancreatic Hodgkin lymphoma was reported, emphasizing the need for tissue diagnosis before definitive treatment. The patient's symptoms and imaging findings initially raised concern for pancreatic adenocarcinoma, but a biopsy revealed nodular sclerosis subtype of Hodgkin lymphoma.
Longevity clinics have emerged globally, offering advanced diagnostic services and customized lifestyle interventions to extend healthspan. However, concerns arise from lack of scientific validation, high costs, and limited access to populations most at risk for premature aging.
Researchers discovered that folate receptor beta is widely expressed in various pediatric and adolescent solid tumors, making it a promising target for improving tumor surgery accuracy. Pafolacianine, a next-generation dye targeting folate receptors, shows promise as a tumor-agnostic imaging strategy for pediatric cancer surgery.
Researchers found that overactive Runx1 gene accelerates age-related degeneration of intervertebral discs, causing premature cellular aging and unhealthy tissue changes. Targeting Runx1 may be a promising strategy to prevent or slow disc aging.
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
Epithelioid hemangioendothelioma is a rare and potentially malignant vascular tumor that can be mistaken for benign conditions. A new case report highlights the diagnostic challenges raised by rare tumors and emphasizes the need for vigilant evaluation of slow-growing swellings.
The Arcadia grant has enabled the creation of IUCN’s Open Access Policy and upgraded the IUCN Library, making over 1,500 historical publications available online. This has improved access to conservation knowledge and secured the scientific integrity of nature conservation efforts.
The report highlights ten breakthrough innovations that can help society operate within planetary boundaries and foster a more sustainable relationship with Earth's systems. These technologies offer scalable solutions to cut emissions, regenerate natural systems, and enhance resilience across food, water, energy, and infrastructure.
Researchers have developed a novel treatment approach using amplitude-modulated radiofrequency electromagnetic fields to slow glioblastoma cell growth and target tumor stem cells. The therapy shows promise in both laboratory experiments and clinical trials with two patients, demonstrating potential for treating brain cancer.
Researchers found that a supplement containing high-molecular-weight hyaluronan preserves muscle mass and exercise capacity in aging mice. The study suggests that targeting the glycocalyx may be a viable therapeutic strategy to treat age-related physical dysfunction.
Frontiers' revolutionary AI-powered FAIR² Data Management service is transforming the way scientific data is shared, enabling researchers to fuel progress and earn credit for their work. The service ensures every dataset is preserved, validated, citable, and reusable.
A recent study published in Oncoscience found that lifestyle choices and hormonal imbalances significantly impact male fertility in Indian men. The research discovered a strong association between poor habits such as tobacco and alcohol use, heat exposure, and body weight with lower semen quality and higher DNA damage.
This study found that aged rats living in socially enriched environments retained better memory and cognitive flexibility than those housed alone. Socially housed rats showed increased activity in the hippocampus and reduced overactivity in the anterior cingulate cortex, suggesting a more balanced and efficient neural response.
The Indo-Swiss Workshop on 'Research Integrity in the Age of AI' brought together policymakers, scientists, and publishers to explore responsible AI use. Frontiers shared its pioneering approach to detecting research fraud using human-in-the-loop AI systems.
ACTM-838, a novel bacterial immunotherapy, enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity. The therapy shows durable anti-tumor efficacy and synergizes with anti-PD1 drugs, improving outcomes in treatment-resistant tumor models.
Imperial College London and the University of Sheffield have signed up to eLife's uncapped scheme, promoting greater equity and inclusivity in scientific publishing. The partnerships aim to support researchers in publishing through eLife Model, providing a fairer and more transparent approach to research publishing and assessment.
A new study found that miR-145-5p and miRNA-27b-3p interfere with fat cell formation in children with Hutchinson-Gilford progeria syndrome, a rare and fatal premature aging disorder. These microRNAs silence genes required for fat cell growth and function, suggesting they could be a promising therapeutic strategy to restore fat tissue.
The 2025 Canada Gairdner Awards winners have published a new volume of articles in Frontiers for Young Minds, sharing their breakthrough science on topics such as cancer and childhood malnutrition. The articles are peer-reviewed by FYM's community of young reviewers and aim to empower kids to see themselves as future innovators.
A new study calls for standardized, transparent, and reproducible methods to evaluate frailty in preclinical aging studies. The researchers analyzed 18 rodent studies and found substantial variation in how frailty is defined and measured.
The journal has appointed 13 distinguished researchers from around the world to expand its representation across stem cell science disciplines. The new Editorial Board members include experts in basic biology, translational research, clinical application, and ethical considerations.
European leaders must assert leadership in global data governance while strengthening scientific collaboration, according to experts. Open science principles are crucial for data sovereignty and resilience, enabling Europe to capitalize on AI and address inequalities.
Researchers found that a combination of oxytocin and an Alk5 inhibitor significantly extended the lifespan and healthspan of frail, elderly male mice, but not female mice. This dual-drug approach reduced chronic inflammation and tissue damage, leading to improved physical endurance and memory in males.
The Public Library of Science (PLOS) has partnered with the Manipal Academy of Higher Education (MAHE) in India, allowing MAHE researchers to publish unlimited in all PLOS journals through 2026. This agreement shifts publishing costs from authors to research institutions, promoting open access and barrier-free publishing.
Marcin Wiorek joins Nota Lepidopterologica as co-Editor-in-Chief, succeeding David Lees. He brings expertise in Lepidoptera systematics and phylogeny to the journal. Wiorek's research focuses on tiger moths and has been recognized with a recently obtained PhD.
The GDPR did not significantly affect EU and US news websites' ability to produce high-quality content, engage users, or receive traffic. Despite initial tracking reductions, EU sites stabilized at lower levels while using consent mechanisms, with no negative impact on visitor engagement.
Pensoft Publishers has forged a new scholarly partnership with the Vietnam Academy of Science and Technology, aiming to enhance research accessibility and innovation globally. The collaboration will utilize ARPHA's publishing platform for Vietnam's scientific journals, books, and research outputs.