Articles tagged with Open Access
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The Open Access Team, led by Sergei Kurenov, rides to support cancer research and honor Dr. Mikhail Blagosklonny's legacy through open-access publishing. Impact Journals is sponsoring the team in this year's Ride for Roswell event.
Researchers found that cigarette smoke and reduced DNA repair capacity combine to increase cancer risk, with normal lung cells showing extensive damage after smoke exposure. The study's findings support a 'double hit' model, highlighting the critical role of XPC protein in preventing DNA damage.
The Longevity & Aging Series has been honored with a Silver Award for 'Excellence in Video/Film' at the inaugural EPIC Awards celebration. The series is praised for its impactful storytelling and production quality, making it a trusted resource for scientists, clinicians, and the broader public.
Researchers found that CBR3-AS1 and PCA3 were significantly overexpressed in gastric cancer tissues, suggesting their involvement in GC development. The study supports the use of these lncRNAs as diagnostic biomarkers.
More than 90% of staff at Universitat Jaume I believe research results should be accessible online without restrictions. Open access is identified as a driver of scientific and social innovation, with 84% supporting institutional strategies promoting open environments.
Researchers identified a novel region in AR that binds to PCNA, and developed a small peptide to mimic this region, blocking the AR-PCNA connection. This approach reduced cancer cell growth, particularly in patients with limited treatment options.
The Top 10 Emerging Technologies of 2024 collection empowers young minds to understand and question innovations that could soon change how we live, work, and care for the planet. Reviewers aged 8-15 helped ensure content is clear and engaging for their peers.
A new editorial proposes a transformative shift in healthcare focus from reactive disease management to proactive healthspan extension. The approach targets the root causes of age-related diseases through aging biology, aiming to prevent diseases before they emerge.
Researchers discovered that blocking PRDX1 protein can make ovarian cancer cells more responsive to DNA-damaging platinum therapies. The study suggests targeting PRDX1 could be a viable strategy to improve chemotherapy efficacy.
Researchers found that aging increases the brain's vulnerability to low oxygen levels, disrupting the blood-brain barrier and leading to inflammation and cognitive decline. The study identified specific oxygen levels that trigger BBB disruption, with older mice showing increased sensitivity even at mild hypoxic levels.
A study investigated immune-related adverse events (irAEs) in Latin American patients with advanced liver cancer treated with atezolizumab and bevacizumab. Most irAEs were mild or moderate and resolved within a month, without impacting overall survival.
A new research paper published in Aging-US identified unintentional weight loss as the strongest predictor of fall risk among Taiwanese elderly. The study found that analyzing each frailty feature individually provided more accurate predictions of fall risk than using a broad frailty label.
A 25-year review highlights the stomach cancer-fighting potential of Brazilian plant species, which contain bioactive compounds with potential anticancer properties. The studies suggest that regular consumption of fruits and vegetables rich in polyphenols and flavonoids may help lower the risk of stomach cancer.
UNAM and Taylor & Francis announce a three-year agreement to publish research articles in over 2,400 journals. This move aims to boost the global reach and impact of UNAM's research.
Researchers review clinical and scientific advances combining radiation therapy with immunotherapy to strengthen the immune response and improve disease control. The approach may offer new treatment options for patients facing hard-to-treat forms of bladder cancer.
Researchers found that consuming foods high in methyl adaptogens, such as green tea and berries, can reduce markers of epigenetic aging. The study, which involved middle-aged men, suggests that targeted food choices may help slow the aging process.
Over 16,000 Pensoft articles are now available on the BHL platform, complete with full-text PDFs and metadata. This integration enhances accessibility for researchers seeking biodiversity information.
A new DNA-based blood test using PhasED-Seq technology detects minimal residual disease (MRD) in B-cell malignancies, offering a powerful tool for early detection and monitoring treatment response. The assay demonstrates exceptional performance and high accuracy in detecting cancer cells in the bloodstream.
A nationwide cohort study found that immune checkpoint inhibitors significantly increase the risk of myocarditis in NSCLC patients, with a 7.4-fold increase in risk compared to non-users. Cardiac monitoring for at least six months following ICI initiation is recommended.
A systematic review and meta-analysis found that individuals with blood type A have a significantly higher risk of developing breast cancer compared to those with blood type O. The research, which pooled data from over 13,000 breast cancer patients and 717,000 controls, suggests an 18% increased risk associated with blood type A.
A new study found that patients using factor Xa inhibitors experienced significantly fewer cardiovascular problems than those on other anticoagulants. Researchers followed over 1,000 patients aged 80 and above for up to five years, revealing lower rates of heart failure, artery disease, and cardiovascular death.
The 'How Equitable Is It?' tool, now updated with community feedback, evaluates scholarly communication models based on seven core assessment criteria. The new version offers clearer guidance and definitions for assessing equity in publishing arrangements.
A new study published in Aging (Aging-US) Volume 17, Issue 4 has found that the drug buthionine sulfoximine (BSO) produces similar reductions in fat mass and weight gain as the sulfur amino acid-restricted diet. BSO may offer a practical alternative to difficult-to-maintain diets for treating obesity.
Researchers discovered that METTL3, an oncogene, regulates the expression of SMAD4 via miR-146a-5p in OSCC. This pathway can potentially have therapeutic implications for treating oral squamous cell carcinoma.
The Scientific Annals of the Danube Delta Institute (SADDI) joins Pensoft's portfolio as an open-access, peer-reviewed journal. SADDI publishes research in ecology, biodiversity, environmental protection, and sustainable development related to the Danube Delta and similar wetland ecosystems.
GigaScience Press has won the first-ever Crossref Metadata Award, recognizing its efforts in providing high-quality metadata for its journal GigaByte. The award highlights the press's commitment to making research more discoverable and accessible through rich metadata standards.
The PEARL trial found that low-dose rapamycin improved lean muscle mass and reduced pain in women, while also showing improvements in emotional well-being. The study suggests rapamycin may offer measurable benefits for physical function and overall well-being in older adults.
The partnership will expand open access scholarship through Direct to Open, featuring multiple package options combining content from both presses. Duke University Press brings its humanities and social sciences catalog to the program.
Researchers found that fisetin reduces calcium buildup and protects blood vessels from hardening in vascular smooth muscle cells. Fisetin's anti-calcification activity depends on the phosphatase DUSP1, which inhibits p38 MAPK.
Impact Journals will exhibit its publications, including Aging-US, Oncotarget, and Genes & Cancer, at the SSP 47th Annual Meeting. The event aims to reimagine the future of scholarly publishing and aligns with Impact Journals' mission to foster open and impactful scientific communication.
Nicolas Hubert joins Zoosystematics and Evolution as Deputy Editor-in-Chief, bringing experience and expertise in ichthyology and genetics. He will drive further development and growth of the open-access journal.
Aging-US invites submissions for a Special Collection on cellular senescence, focusing on its mechanisms, physiological and pathological functions, and clinical applications. The collection honors Dr. Judith Campisi's groundbreaking work on senescence in aging, cancer, and tissue homeostasis.
A new study found that increased perceived stress can lead to worsened respiratory symptoms and decreased quality of life in individuals with chronic obstructive pulmonary disease (COPD). The study also examined the association between stress and platelet activation, oxidative stress, and systemic inflammation.
Researchers have discovered that inhibiting the metalloprotease ADAM19 can reduce gut inflammation and cell aging markers across species. The study found that blocking ADAM19 reduced gut damage and inflammation in fruit flies, mice, and human cells, offering a promising path for creating treatments to maintain healthy tissues.
Two Taylor & Francis journals will be converted to open access for 2025, thanks to funding from collective OA agreements and read access. The Collective Pathway to Open Publishing model combines multiple funding sources to support the conversion of HSS journals.
Researchers found that high-grade pre-cancer lesions triggered stronger immune responses and showed higher levels of immune-related markers PD-L1 and FOXP3. These findings suggest that HPV may begin avoiding the immune system early in infection, allowing infected cells to grow and potentially leading to cancer.
A large-scale database of macaque behavior is driving a shift towards open science, bringing together researchers from across the globe to share data on social lives of over 3,000 individual monkeys. The platform has grown into a collaborative effort promoting culture of sharing within the research community.
A study on captive olive baboons found that about a quarter exhibited accelerated aging, while another quarter showed signs of slower aging. The researchers investigated physical indicators such as walking speed and fine motor skills, but found that these changes were more closely related to chronological age than epigenetic age.
A team of Singaporean scientists has released a comprehensive long-read RNA sequencing dataset, SG-NEx, to accelerate biomarker discovery and precision medicine. The dataset offers deeper biological insights into RNA complexity, enabling researchers to detect clinically relevant biomarkers and develop better treatments.
SKINdeep, a new international journal on translational dermatology and clinical studies, is now available online. The journal features original articles, reviews, and perspectives on skin diseases and their therapeutic relevance.
The journal will publish research exploring digital health and advance care planning for older adults, including caregiver integration and technological innovation support. JMIR Aging boasts a strong impact in the field, with a Journal Impact Factor of 5.0 and a CiteScore of 6.5.
The Frontiers Planet Prize has announced 19 National Champions from science research teams worldwide, offering transformative solutions to climate change, community health, and planetary resilience. The prize aims to fast-track innovation and global consensus on planetary health.
Participants who took the supplement showed improvements in grip strength, lower body mobility, and reductions in body weight. The supplement appeared to reduce stem cell turnover, regulate immune function, and influence gene activity related to stress response.
The American Physical Society has received the leading score among publishers participating in SCOAP3 for its investment in open science practices. The Society earned high marks in elements like data availability, article metadata, and persistent identifiers.
Researchers developed a new method to measure changes in DNA that can help predict a person's age, focusing on how random chemical tags become over time. The study found that methylation entropy predicted age as accurately as traditional methods, with an average error of just five years.
A new study finds that a specific genetic variation in the PTGS2 gene is associated with an increased risk of benign prostate hyperplasia (BPH) in Lebanese men. Men carrying the C version of this gene were more than twice as likely to have BPH compared to those without it.
The Leopoldina discussion paper suggests establishing a diamond open access model, where journals are funded and monitored like research itself. The authors propose an application process and regular evaluation to guarantee lasting quality and transparency while reducing costs.
Researchers discovered that aging causes inflammation, oxidative stress, and gene disruption in the retinal pigment epithelium, a vital layer of cells in the eye. This study provides a clearer understanding of why aging leads to eye disease and introduces a reliable laboratory model for testing new therapies.
Researchers found that GSK3β becomes increasingly active in melanoma cells during treatment, helping them survive and adapt despite BRAF inhibitors. Treating resistant cancer cells with a GSK3β inhibitor significantly reduced their growth, suggesting blocking this protein could restore sensitivity to treatment.
A study found that smaller embryos already hatching are more likely to be chromosomally normal. This insight helps fertility clinics select better embryos during IVF, particularly for women over 35 or those undergoing PGT-A.
Xiamen University has joined the Bentham Science Institutional Membership Program to enable researchers to publish Open Access at concessionary rates in Bentham Science journals. The program promotes open research and fosters scientific advancements globally.
A new editorial in Oncotarget discusses how artificial intelligence can improve liver imaging by recognizing when it might be wrong. The approach, called 'uncertainty quantification,' helps clinicians better detect liver cancer and other diseases by pointing out areas in medical scans that need a second look.
Researchers investigated why bones become less responsive to exercise with age, finding increased mtROS or decreased Atg7-dependent autophagy in osteoblastic cells do not contribute to reduced mechanoresponsiveness. Damage to the bone's osteocyte network also does not prevent a healthy bone-building response.
Researchers found that combining imipridones with radiation therapy and temozolomide slowed glioblastoma growth and prolonged survival in mice. The treatment also boosted immune responses and suppressed MGMT protein expression, making it more effective.
A new case report presents a highly unusual combination of two benign ovarian tumors: serous cystadenofibroma and collision lesions. Accurate preoperative diagnosis is critical for effective treatment planning, and this case emphasizes the need for personalized evaluation of each ovarian mass.
Three Taylor & Francis journals will be published open access in 2025 volumes with no cost to authors. Institutional support has reached the required threshold for the Subscribe to Open pilot, enabling OA publishing.
Researchers found that NSD2 helps maintain MM cell identity by reorganizing DNA and influencing gene activity. This discovery could shape future treatment approaches for patients with t(4;14) myeloma.
The partnership streamlines access to biodiversity data, enabling users to search and refine queries based on various criteria. Pensoft's hosted portals provide a scalable solution for 30 journals, fostering greater connectivity between scientific research and evidence.
The Public Library of Science and the Society of China University Journals have formed a strategic partnership to promote open access, open science, and research integrity. The collaboration aims to increase awareness of open science principles and enhance research quality in China.
IOP Publishing is introducing a new policy for two environmental research journals, ERFS and ERCL, requiring authors to publicly share research data underpinning articles. The policy aims to foster greater access to research data and cultivate transparency and trust in science.