News on open-access publishing and its reach. Covers journal launches, open-access agreements, and research made freely available.
A study profiles mitochondrial circular RNAs in Peripheral Blood Mononuclear Cells from young and old human cohorts, revealing that circMT-RNR2 levels are depleted in older cohorts and are involved in promoting the TCA cycle. Loss of GRSF1 reduces circMT-RNR2 levels, decreasing mitochondrial TCA intermediates and accelerating cellular ...
A mathematical model suggests paths forward to stabilize peer review, as rising submissions imperil the process. The study identifies key factors contributing to the strain on peer reviewers.
A new study examines the mechanisms, clinicopathological features, and management strategies of GI toxicity induced by targeted cancer therapies. The authors highlight the importance of close collaboration between oncologists, gastroenterologists, and pathologists to ensure accurate diagnosis.
Researchers developed a new single-cell transcriptomic clock called Tictock to measure aging in specific immune cells. The study found that COVID-19 and HIV alter T cell composition and accelerate the biological age of naïve CD8 T cells, while long-term antiretroviral therapy stabilizes T cell proportions.
Advances in Pollinator Research is a community-driven peer-reviewed journal championing research from underrepresented regions and taxa. It aims to find and amplify solutions to pollinator decline through transdisciplinary collaboration.
Researchers highlight polyploidy-induced senescence as a coordinated biological program that may drive aging, tissue repair, and cancer risk. Polyploidization in healthy tissues could help maintain organ structure and barrier integrity, but its instability can promote chromosomal instability and malignant transformation.
A new commentary raises concerns about editorial bias in scientific publishing, particularly in relation to COVID-19 vaccine safety and efficacy. The authors highlight the rejection of a case report and literature review that raised potential links between mRNA vaccines and rare blood cancers.
A case report investigates a woman's development of acute lymphoblastic leukemia and lymphoblastic lymphoma after receiving her second dose of the Pfizer-BioNTech COVID-19 mRNA vaccine, highlighting potential genetic and molecular mechanisms involved in disease pathogenesis.
Researchers found that an experimental compound SB-216 reduced the growth of pancreatic ductal adenocarcinoma cells by inhibiting oncogenic microtubules and mitochondrial function. This approach may reduce cancer cell adaptation and survival.
ResearchGate and Pensoft Publishers announce the expansion of their Journal Home partnership, now covering 40+ journals affiliated with well-known institutions. The partnership provides increased visibility and engagement opportunities for smaller and niche research journals.
More than 1,000 institutions have joined MDPI's Institutional Open Access Program (IOAP), spanning 59 countries. The agreements provide streamlined submission processes and discounted Article Processing Charges, increasing accessibility for global research communities.
JMIR Publications introduces a new merit-based reward system, Karma, to recognize and reward high-quality peer reviews. The program provides incentives tied to the depth and rigor of feedback, ensuring that reviewers are properly honored for their contributions.
The expanded partnership strengthens researcher collaboration, increases open access opportunities, and fosters the impact of trusted knowledge. Researchers can discover and access relevant content through ResearchGate's Community Engagement Upgrade, while Taylor & Francis editors use new tools to grow their journals' communities.
A rare case of hyperammonemic encephalopathy caused by 5-fluorouracil (5-FU) chemotherapy has been reported, highlighting the importance of monitoring neurological symptoms in patients receiving 5-FU. The patient's symptoms resolved after stopping 5-FU and administering lactulose and intravenous fluids.
Researchers have developed an open-source pressure myography tool, HemoLens, which reduces the cost of vascular research to $750 from $40,000. The tool uses affordable manufacturing processes and customizable components, making it easier for researchers to study vascular function.
Researchers at participating institutions can now publish without paying individual Article Processing Charges (APCs) in 65 peer-reviewed journals published by Pensoft or hosted on its ARPHA platform. This partnership ensures open access to research under FAIR principles, making data Findable, Accessible, Interoperable, and Reusable.
Early recognition and surgical management are crucial in treating necrotizing fasciitis of the head and neck, a rare but life-threatening soft tissue infection. The authors emphasize the urgent need for coordinated care, including immediate surgery, broad-spectrum antibiotics, and airway protection to reduce mortality rates.
Sangwoo Lee brings over 20 years of experience in communications to lead MDPI's operations in South Korea. The appointment coincides with the launch of MDPI's 500th journal, Journal of Innovation, with Prof. Dr. Junic Kim as founding Editor-in-Chief.
The State of Open Data report shows open data has become embedded into research practice with FAIR awareness widely recognized. Researchers need systems that reward openness and workflows that make sharing effortless to sustain progress.
Pensoft has welcomed the Swiss Journal of Palaeontology (SJP) and Swiss Journal of Geosciences (SJG) to its portfolio. Both journals have transitioned to open-access models, leveraging Pensoft's ARPHA publishing platform for streamlined processes and increased visibility.
Antimicrobial resistance is a fast-growing global threat that could kill more people than cancer by 2050. Scientists discussed data integrity's importance in enabling innovation and adoption during the Frontiers Science House session. A new AGI paradigm grounded in real-time interaction may be needed to overcome current limitations.
Alo Blac urges data sharing to accelerate cancer precision therapeutics and unlock the disruptive potential of quantum technologies. Researchers, funders, policymakers co-create a forward-looking science roadmap to drive public benefit and private-sector innovation by 2035.
The JEDI Draghi Tracker measures Europe's implementation of the Draghi report on competitiveness, focusing on 20 impactful measures. Currently, only 14% has been implemented after 15 months.
The event highlighted urgent global risks and science-led solutions for antimicrobial resistance, trust in data, and AI-enabled sustainable cities. Experts emphasized the need for immediate actions against AMR, which could kill more people than cancer by 2050.
The AI Polis platform offers a city-level coordination system to design, prioritize, and scale projects that improve urban life while staying within planetary boundaries. By connecting technology, policy, finance, and environmental science, it guides cities in strengthening communities while protecting the planet.
A rare diagnosis of a giant solitary neurofibroma in a 13-year-old boy was successfully treated with microsurgery. The tumor's location deep within the thigh along the sciatic nerve made it challenging to diagnose and treat, but careful surgical technique and postoperative care ensured optimal outcomes.
SPARK Microgravity plans to build Europe's first dedicated commercial orbital cancer lab, allowing researchers to run experiments impossible on Earth. This will accelerate the path from discovery to therapy, with microgravity enabling 3D tumor growth and revealing new drug targets.
Journals JDR and JDR Clinical & Translational Research now require open data sharing to facilitate replication, systematic reviews, and data reuse. This move aims to maximize the benefits from research investment and ensure transparency.
Antimicrobial resistance is expected to kill more people than cancer by 2050 due to increasing public mistrust and delayed policy-making. Experts urge immediate global action against AMR, emphasizing the need for trust in science, transparency, and openness to address this growing threat.
The Estuarine Management and Technologies journal has been accepted into the Directory of Open Access Journals, a key scientific index. The journal's recognition signifies its compliance with global standards of ethics, transparency, and quality.
A comprehensive Open Access (OA) agreement has been signed by Pensoft and the Bibsam Consortium, benefiting 97 research institutions in Sweden. Researchers can publish their findings without individual article processing charges, promoting accessible science and supporting global challenges.
A new review proposes a two-stage model explaining how different determinants of aging interact to generate late-life disease. Early-life damage and late-life genetic activity are identified as key drivers of age-related illnesses.
The Frontiers Science House officially opened in Davos, bringing together scientists, policymakers, and industry leaders to address societal challenges through open science. The week-long program highlights the importance of openness, trust, and data sharing in accelerating technological innovation and solving global issues.
Research finds age-related DNA methylation alterations in sperm may contribute to autism risk in offspring. Advanced paternal age is associated with specific changes in sperm DNA, influencing early development in children.
Researchers found that CD47 knockdown improves glucose homeostasis and alleviates dyslipidemia in aged male mice by reducing visceral fat and enhancing brown fat tissue function. This breakthrough suggests CD47 as a key regulator of age-related metabolic dysfunction.
A new hypothesis article proposes that HPV E6 and SARS-CoV-2 spike proteins could cooperate in suppressing host defenses including tumor suppressor mechanisms involving p53. Laboratory studies suggest that combined viral pressures on tumor-suppressor pathways may contribute to cancer progression.
JMIR Publications' JMIR Neurotechnology journal now accepts submissions on novel technological advances for neurological disorders. Researchers can submit review articles exploring emerging technologies, such as neurofeedback, neurosurgery, and brain-machine interfaces.
Researchers in Hong Kong will have greater opportunities to share their work with a global audience through an open access agreement between JULAC and Taylor & Francis. The partnership enables OA publishing in over 2,000 journals without payment of an OA article publishing charge.
A gathering of over 100 scientists and leaders from 16 countries will discuss open science, health, climate, technology, and governance. The program includes sessions on quantum technologies, AI, and genomic data exchange.
The JMIR-Bibsam partnership has seen a 40% increase in annual publishing by Swedish authors, with over 130 digital health articles published without author payment. The renewed agreement simplifies the publishing process, allowing corresponding authors to publish immediately upon publication.
A global review of COVID-19 vaccination and infection cases found associations between the two and certain types of cancer. The study analyzed 69 publications and identified potential biological mechanisms, including immune responses and inflammation.
The meeting report highlights the emerging importance of infection-driven senescence in understanding chronic diseases, including respiratory viruses like influenza and SARS-CoV-2. Researchers found that senescent cells contribute to persistent inflammation and reduced healing, particularly in older adults during chronic infections.
Researchers identified common aging-related alterations in genes involved in RNA splicing and processing across eight human tissues. These findings suggest a shared biological response to aging, pointing to the importance of RNA processing in accurate protein production.
A new study introduced epigenetic clocks in skeletal muscle from an Asian population, identifying DNA methylation sites associated with age and developing accurate age prediction models using NGS and SBE. The findings offer a reliable method for estimating age and its potential applications in forensic science.
A new study analyzed over 460,000 scientific abstracts to identify key themes, trends, and research gaps in aging research. The study found a growing separation between basic biological studies and clinical research, highlighting the need for integration to translate laboratory discoveries into medical applications.
A new study validates OVCAR3 as a reliable model for high-grade serous ovarian carcinoma, providing insights into disease behavior and potential therapeutic targets. The research also explores the effects of repurposed drugs on ovarian cancer cells, revealing promising results for treatment responses.
Research found that older women with younger biological ages were more likely to experience increased depressive symptoms during the pandemic. The study suggests that this may be due to reduced social connections and daily routines, which can affect mental health.
Researchers at participating UK institutions will benefit from a renewed and expanded agreement offering over 2,400 journals with open access publishing options. The partnership also enables the expansion of AI use in licensed Taylor & Francis proprietary content for non-commercial research and educational purposes.
A systematic review found that pancreatic cancer surgery significantly increases the risk of new-onset diabetes mellitus (NODM), particularly in patients with known risk factors. The study analyzed 45 studies and found an overall incidence of NODM of 24.5%, with a higher rate in those who underwent distal pancreatectomy.
Researchers used machine learning to combine clinical data with biological markers, achieving 89.58% accuracy in predicting patient survival. The study identified key markers such as E2F8, WDR77, and hsa-miR-495-3p, which were associated with tumor growth and cancer development.
The journal has integrated ResearchGate to improve accessibility and impact of research on aging. This allows authors to connect their work with a wider network of peers, fostering collaboration and advancing understanding of the biology of aging.
A study compares article-level metrics with journal-level metrics, finding that most influential papers are published in lower-tier journals. Article-level data provides more recognition to most researchers than journal-level metrics.
Researchers found that higher levels of theobromine are associated with slower biological aging in humans, as measured by epigenetic markers such as DNA methylation and telomere length. The study suggests that theobromine may support healthy aging by influencing molecular epigenetic processes.
AI is becoming increasingly used in peer review, with 53% of reviewers now utilizing AI tools to enhance research quality and trust. The study highlights significant untapped potential for AI to support rigor, reproducibility, and deeper methodological insight.
The five-year partnership aims to equip Hiroshima University researchers with new open policies, promoting transparency and accessibility in their work. The collaboration will also provide practical guidance on open publishing pathways and encourage reform of the research evaluation system.
Researchers found that glycation stress, caused by methylglyoxal, promotes aortic stiffening and cellular senescence. Natural compound Gly-Low, containing nicotinamide and alpha-lipoic acid, reversed these effects and reduced stiffness in aging mice.
A case report describes a woman with radiation-induced cellular changes in her Pap smear that mimicked cancer recurrence. The study emphasizes the importance of recognizing these changes to prevent misdiagnosis and unnecessary medical procedures.
Researchers in Australia and Aotearoa New Zealand will have expanded open access publishing options through a new three-year agreement. The partnership supports fully open access journals and enables the expansion of AI use in teaching and research.
This study found that older mice blood worsens Alzheimer’s-related changes, while younger blood improves memory and cognitive function. The researchers identified key proteins involved in neurodegeneration and inflammation, suggesting new avenues for targeting blood-borne factors to slow or modify disease progression.
Researchers found that sudden cardiac death (SCD) among colorectal cancer patients decreased overall, but disparities remained based on age, sex, and geographic location. The study highlights the need for tailored heart monitoring and care strategies for cancer patients, particularly in underserved groups.