Patients undergoing bilateral total knee arthroplasty are at a higher risk of complications such as pulmonary embolism, stroke, and blood loss anemia compared to those undergoing unilateral TKA. The study found that the risks of these complications were approximately doubled in the bilateral TKA group.
Research leaders collaborate with organizations and regulators to develop digital tools for Parkinson's clinical trials. The Digital Drug Development Tools initiative accelerates the regulatory endorsement of these tools, enabling more objective and patient-centered measures.
A new study published in Wildlife Society Bulletin reveals that lead exposure from hunting ammunition is sickening and killing bald eagles, making them more susceptible to other dangers. The research, funded by Morris Animal Foundation, used innovative modeling tools to demonstrate the impact of lead poisoning on eagle populations.
Researchers demonstrate that AI language models like ChatGPT can generate high-quality fraudulent medical articles with standard sections and references. The study highlights the need for increased vigilance and enhanced detection methods to combat potential misuse of AI in scientific research.
A study published in Management Science found that the UK's Covid vaccine mandate caused a 3-4% reduction in staffing in elderly care homes, equivalent to 14,000 to 19,000 employees. The policy led to an increase in reliance on agency workers and persisted even after the mandate was lifted.
A recent study published in Science of the Total Environment found a scarcity of studies on microbial and chemical drinking water contamination in Appalachia and associated health outcomes. Only 85 publications met the criteria, with many gaps remaining to be filled.
The study investigates the effects of DPDT on human colon cancer HCT116 cells and non-tumorigenic MRC5 fibroblasts. The results show that DPDT preferentially targets HCT116 cells, inducing apoptosis and G2/M cell cycle arrest, likely through DNA topoisomerase I poisoning.
Researchers found that treatment with tranexamic acid (TXA) is associated with a decreased incidence of heterotopic ossification (HO), a common complication of abnormal bone formation. The study showed a significant reduction in HO risk, with an odds ratio of 0.49 and a 50% lower risk compared to patients not receiving TXA.
Researchers discuss the potential of glucocorticoid-induced TNFR-related protein (GITR) as a target for cancer immunotherapy. Preclinical studies have shown potent anti-tumor efficacy, but clinical trials have yielded inconsistent results due to complexities in immune responses and antibody structure.
A new study by CNIC researchers reveals that low-grade systemic inflammation triggered by subclinical atherosclerosis accelerates epigenetic aging in otherwise healthy young individuals. The study found a strong association between atherosclerosis progression and accelerated biological age, with potential reversibility through lifestyl...
A second-generation all-inside meniscal repair system demonstrates a high successful repair rate of 84-88% at 10 years, with low failure rates and no correlation to patient characteristics or surgical techniques. Patient-reported outcomes improve after meniscal repair and ACL reconstruction.
A new study published in JMIR Cardio reveals the potential of AI-QCA in analyzing coronary angiography, providing accurate measurements of coronary stenotic lesions similar to IVUS. This technology has the potential to improve patient outcomes and support clinical decision-making.
Researchers from Universitat de Barcelona and Universitat Internacional de Catalunya discuss the non-receptor protein tyrosine kinase Src as a good example of an oncogene. Targeting the Src N-terminal regulatory element (SNRE) has potential as oncotargets to inhibit Src activity only in cancer cells.
A team of researchers developed a tool to identify AI-generated academic science writing with high accuracy, using characteristics such as predictability, paragraph structure and vocabulary. The model outperformed existing AI text detectors and has potential applications in assessing student essays.
SourceCell Press·JournalCell Reports Physical Science·TypeComputational simulation/modeling·DateJun 7, 2023
The American Phytopathological Society published a special issue on key discoveries in plant pathology, highlighting groundbreaking findings over the past 50 years. These discoveries have significantly impacted plant health, food security, and food safety worldwide.
Researchers found GRB 221009A's jet exhibited a narrow core with wide sloping wings, differing from standard jets. This unique structure may explain the event's extreme energy release and prolonged visibility.
A study published in JMIR Formative Research found that wearable sleep devices show promise in positively impacting sleep health among marginalized populations. Participants perceived the device as easy to use and comfortable to wear, suggesting its potential for improved sleep health. However, barriers to adoption, such as housing sta...
Researchers successfully detect X-ray signature of individual atoms, enabling the identification of materials at an atomic level. The breakthrough technique has potential applications in environmental and medical sciences, as well as advancing technology.
Researchers can reduce stigma in scientific literature by implementing practices such as referencing language guides, updating terminology, and connecting with the community. This change is crucial for promoting non-stigmatizing language and respecting preferred terms used by individuals living with HIV.
Three Amazonian Morpho butterfly species have been sequenced for the first time, revealing genetic differences that maintain reproductive isolation despite sympatry. The study found Z-chromosome rearrangements and genetic divergence among gene copies, suggesting a role in speciation.
Global experts have developed a new checklist called iCHECK-DH to standardize the quality of reporting and improve implementation standards for digital health technologies. The 20-item checklist aims to aid researchers and practitioners in ensuring complete, accurate, and consistent reports.
Paderborn researchers develop innovative approach to generating higher harmonics in silicon metasurfaces, increasing efficiency through the Fano effect. The study enables third harmonics to be generated much more efficiently than with previous known structures.
A new study from City University London suggests that the Research Excellence Framework (REF) has led to significant increases in high-quality published research, but not active academics. The study highlights areas of improvement needed in the assessment framework, including greater collaboration between domestic competitors.
A study published in The Journal of Bone & Joint Surgery reports high 10-year implant survival and patient satisfaction rates for robotic-assisted medial knee arthroplasty. The procedure showed excellent outcomes, with over 90% of patients remaining satisfied without revision.
A new study published in JMIR Diabetes found that Fitterfly's diabetes digital therapeutics program improved glycemic control and weight management in participants with type 2 diabetes. The 90-day program led to significant reductions in hemoglobin A1c levels and body weight.
A new systematic literature review reveals that virtual consulting can reduce carbon emissions in healthcare by minimizing patient travel time. The review found significant reductions in carbon emissions through the adoption of telemedicine appointments and video-based visits, which will continue to mitigate climate change as health sy...
The Journal of Dental Research (JDR) has published a special issue on aging and oral health, featuring research on biological mechanisms underlying age-related conditions such as cognitive decline. The issue aims to improve oral health care in older populations, promoting general health and well-being.
A comprehensive review of 169 clinical trials found that the effect of fructose-containing sugars on adiposity varies among food sources and energy control. High doses of certain sources, like SSBs, lead to increased body weight, while others, such as fruit and honey, show moderate beneficial effects when consumed in moderation.
Researchers developed a new sociotechnical framework to assess eHealth tool quality and impact. The framework balances technical, social, and organizational aspects and considers implementation challenges.
The 18th Key Symposium on Healthy Ageing and Longevity takes place in Okinawa, bringing together world experts to discuss the latest research on blue zones. The symposium aims to promote both longevity and healthy ageing to reduce age-related diseases and healthcare burden.
Jeong Min Lee, KSR President and professor at Seoul National University Hospital, is honored with ARRS membership. He has published over 470 scientific articles and serves on the editorial board of several publications.
A new study found that a handful of key Twitter influencers effectively countered vaccine misinformation and promoted accurate information about vaccines. Social media influencers can use their social capital to challenge the spread of conspiracy theories.
Impact Journals will participate as an exhibitor at the AACR Annual Meeting 2023, showcasing Aging's growth in impact factor to 5.955. The meeting theme focuses on Advancing the Frontiers of Cancer Science and Medicine.
Impact Journals' Oncotarget participates in the AACR Annual Meeting 2023, highlighting its focus on oncology and biomedical sciences. The meeting theme of Advancing the Frontiers of Cancer Science and Medicine aligns with Oncotarget's research goals.
A study published in the journal Cancer found that long-term pancreatic cancer survivors have a robust immune response and enriched gut microbiome species, including Faecalibacterium prausnitzii. The research suggests that these bacterial species may promote immune response to pancreas cancer.
A team led by Bill Ballard has published a new study in GigaScience to propose Cooinda, an Alpine dingo, as the model specimen to represent a typical dingo. The study presents genomic and brain imaging data that sheds light on the evolutionary history of dingoes and their domestication process.
The High Seas Treaty aims to establish cooperative approaches to improve ocean management, but scientists argue that more research is needed to effectively implement the agreement. The treaty proposes massive marine protected areas covering 30% of the ocean by 2030, which could significantly improve ocean conservation.
The article provides 12 recommendations to enhance the quality of surveys, including transparency, clarity, and correcting the record. The recommendations aim to address challenges in survey research, such as biased responses and inaccurate forecasts.
A University of Cambridge analysis identified 98% of reports from trials evaluating new school-based physical exercise programs as lacking key details about teacher training. The study urged journal editors to update their submission guidelines to encourage better reporting, with seven journals already altered their guidance.
Researchers at Chalmers University of Technology have developed a propeller design optimisation method that paves the way for quiet, efficient electric aviation. The new design can reduce noise emissions by up to 5-8 dBA, comparable to going from a normal conversation voice to a quiet room.
Higher body mass index patients undergoing unicompartmental knee replacement (UKR) experience lower revision rates with cementless implants, according to a new study. Cementless fixation is preferred in higher-BMI patients, reducing the risk of revision surgery by up to 40%.
A new study shows that transcatheter mitral valve repair significantly reduces hospitalizations by almost 50 percent and death by nearly 30 percent in heart failure patients with severe mitral regurgitation. The procedure, using Abbott's MitraClip system, improves symptoms, reduces hospitalizations, and leads to longer survival.
Using a dual-source CT scanner eliminates the need for beta-blockers and decreases nondiagnostic examinations, resulting in shorter CT completion times. The study found no difference in ED length of stay but demonstrated significant benefits in reducing nondiagnostic examinations.
Bielefeld University researchers developed an AI method using Capsule Networks to analyze genotype profiles of 3,000 ALS patients, achieving 87% accuracy in predicting whether or not people will develop ALS. The study reveals over 900 genes that play a role in identifying the disease.
A recent study found that immunotherapy costs accounted for 84% of the net increase in Medicare spending on outpatient cancer care at the end of life. Payments for radiation oncology decreased by 2%, while palliative care spending rose, reflecting a shift towards hypofractionated radiation treatments.
The third annual Rising Black Scientists Awards recognize four winners from diverse scientific disciplines, including computer science, biochemistry, and conservation biology. The recipients share their aspirations and research goals, highlighting the importance of diversity and inclusion in STEM fields.
The study, conducted by the University of Malaga and others, analyzed the skeleton and brain architecture of Miracinonyx trumani, finding that it had retractable claws and was able to grapple with its prey like cougars. Its brain surface also showed differences from cheetahs, suggesting an intermediate form between the two species.
The use of artificial intelligence (AI) and language models in writing manuscripts has sparked debates about the integrity of scientific publication. AI-generated content can lead to misinformation and compromised academic standards, posing significant risks to medical knowledge.
A global consensus has been reached on 19 open science practices to be implemented and monitored by biomedical institutions. These practices, including open access publishing and data sharing, aim to ensure transparent and accessible research.
A recent study published in PLOS Biology found that individuals with strong attitudes towards science tend to be overconfident about their level of understanding. This suggests that addressing the discrepancy between what people know and believe they know may be a more effective strategy for improving scientific literacy.
A new species record of mesophotic kelp was discovered in the Galapagos Islands, characterized by its extensive and dense kelp forest at depths of ~50m. The research highlights the importance of these forests as ecosystem engineers and supports for marine life, with potential implications for carbon sequestration.
A searchable library of 1,600 chemically-diverse plant extracts has been established, providing valuable insights into plant metabolites' roles in drug development. The library shares both data and methods, making it an exceptional resource for advancing chemodiversity digitization.
A study by NYU Abu Dhabi researchers found that women are consistently underrepresented among scientific journal editors, with fewer female editors publishing their research in the journals they edit. The study highlights the need for diversity and representation amongst editors to foster a more inclusive scientific community.
Researchers have made a breakthrough in precision oncology for patients with metastatic urothelial carcinoma, identifying that certain cell surface molecules decrease or are absent in these patients, making them resistant to the new drug enfortumab vedotin.
A new study from the University of Virginia Health System found that mRNA booster shots increase the durability of antibodies to COVID-19. The boosters led to longer-lasting antibodies, even in those who had previously recovered from a COVID-19 infection.
Researchers have developed a new method for recycling high-density polyethylene (HDPE) into fully recyclable and biodegradable material. The approach uses catalysts to cleave polymer chains, reducing carbon emissions and pollution associated with HDPE.
A new Northwestern Medicine study found that all U.S. OB-GYN subspecialties lack racial and ethnic representation in clinical trials and research publications. This absence has negative consequences, including biased tools for diagnosing endometrial cancer and unacceptably low sensitivity in the Black female population.
Jon A. Jacobson, MD, FACR, has been recognized as the 2023 ARRS Distinguished Educator for his exceptional contributions to radiological education and innovative educational activities. He is a renowned expert in musculoskeletal ultrasound and MRI, with over 250 peer-reviewed publications.
The EU project CRAFT-OA aims to strengthen institutional publishing using Diamond Open Access model across Europe. The project will enable local platforms and service providers to expand their content services with the aim of networking them with other information systems in science.
A Rutgers study found that COVID-19 patients, especially those treated with antibiotics, experience significant disruptions in their gut microbiome balance. This imbalance may lead to the development of targeted probiotic supplements to improve treatment outcomes.