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Atherosclerosis accelerates aging

A new study by CNIC researchers reveals that low-grade systemic inflammation triggered by subclinical atherosclerosis accelerates epigenetic aging in otherwise healthy young individuals. The study found a strong association between atherosclerosis progression and accelerated biological age, with potential reversibility through lifestyl...

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalEuropean Heart Journal·TypeCase study·DateJun 21, 2023

Targeting the Src N-Terminal regulatory element in cancer

Researchers from Universitat de Barcelona and Universitat Internacional de Catalunya discuss the non-receptor protein tyrosine kinase Src as a good example of an oncogene. Targeting the Src N-terminal regulatory element (SNRE) has potential as oncotargets to inhibit Src activity only in cancer cells.

SourceImpact Journals LLC·JournalOncotarget·TypeCommentary/editorial·DateJun 9, 2023

New research suggests sleep wearables show promise in improving sleep health among marginalized populations

A study published in JMIR Formative Research found that wearable sleep devices show promise in positively impacting sleep health among marginalized populations. Participants perceived the device as easy to use and comfortable to wear, suggesting its potential for improved sleep health. However, barriers to adoption, such as housing sta...

SourceJMIR Publications·JournalJMIR Formative Research·DateJun 6, 2023

Research Excellence Framework significantly increases UK university output but not efficiency, study shows

A new study from City University London suggests that the Research Excellence Framework (REF) has led to significant increases in high-quality published research, but not active academics. The study highlights areas of improvement needed in the assessment framework, including greater collaboration between domestic competitors.

SourceCity St George’s, University of London·JournalResearch Policy·TypeObservational study·DateMay 10, 2023

Virtual consulting can significantly cut carbon footprint in health care, new study suggests

A new systematic literature review reveals that virtual consulting can reduce carbon emissions in healthcare by minimizing patient travel time. The review found significant reductions in carbon emissions through the adoption of telemedicine appointments and video-based visits, which will continue to mitigate climate change as health sy...

SourceJMIR Publications·JournalJournal of Medical Internet Research·TypeSystematic review·DateMay 3, 2023

Journal of Dental Research to publish special issue on aging and oral health

The Journal of Dental Research (JDR) has published a special issue on aging and oral health, featuring research on biological mechanisms underlying age-related conditions such as cognitive decline. The issue aims to improve oral health care in older populations, promoting general health and well-being.

New, comprehensive systematic review and meta-analysis illustrate the need for nuance in public health guidance related to consumption of sugars

A comprehensive review of 169 clinical trials found that the effect of fructose-containing sugars on adiposity varies among food sources and energy control. High doses of certain sources, like SSBs, lead to increased body weight, while others, such as fruit and honey, show moderate beneficial effects when consumed in moderation.

SourceAmerican Society for Nutrition·JournalAmerican Journal of Clinical Nutrition·TypeSystematic review·DateApr 26, 2023

Who let the dingo out?

A team led by Bill Ballard has published a new study in GigaScience to propose Cooinda, an Alpine dingo, as the model specimen to represent a typical dingo. The study presents genomic and brain imaging data that sheds light on the evolutionary history of dingoes and their domestication process.

SourceGigaScience·JournalGigaScience·TypeMeta-analysis·DateApr 3, 2023

Researchers call for the science needed to get the ocean we want

The High Seas Treaty aims to establish cooperative approaches to improve ocean management, but scientists argue that more research is needed to effectively implement the agreement. The treaty proposes massive marine protected areas covering 30% of the ocean by 2030, which could significantly improve ocean conservation.

SourceOcean-Land-Atmosphere Research (OLAR)·JournalOcean-Land-Atmosphere Research·TypeCommentary/editorial·DateMar 30, 2023

Transcatheter mitral valve repair in heart failure patients significantly reduces hospitalizations and improves survival

A new study shows that transcatheter mitral valve repair significantly reduces hospitalizations by almost 50 percent and death by nearly 30 percent in heart failure patients with severe mitral regurgitation. The procedure, using Abbott's MitraClip system, improves symptoms, reduces hospitalizations, and leads to longer survival.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateMar 5, 2023

Predicting outbreak of ALS disease with AI methods

Bielefeld University researchers developed an AI method using Capsule Networks to analyze genotype profiles of 3,000 ALS patients, achieving 87% accuracy in predicting whether or not people will develop ALS. The study reveals over 900 genes that play a role in identifying the disease.

SourceBielefeld University·JournalNature Machine Intelligence·TypeData/statistical analysis·DateFeb 28, 2023

Immunotherapy costs drive increase in Medicare spending for outpatient cancer care at the end of life

A recent study found that immunotherapy costs accounted for 84% of the net increase in Medicare spending on outpatient cancer care at the end of life. Payments for radiation oncology decreased by 2%, while palliative care spending rose, reflecting a shift towards hypofractionated radiation treatments.

SourceAmerican Society for Radiation Oncology·JournalInternational Journal of Radiation Oncology*Biology*Physics·DateFeb 27, 2023

Researchers evidence new characteristics of the extinct American cheetah ‘Miracinonyx’

The study, conducted by the University of Malaga and others, analyzed the skeleton and brain architecture of Miracinonyx trumani, finding that it had retractable claws and was able to grapple with its prey like cougars. Its brain surface also showed differences from cheetahs, suggesting an intermediate form between the two species.

SourceUniversity of Malaga·JournalBiology Letters·TypeExperimental study·DateFeb 15, 2023

It isn’t what you know, it’s what you think you know

A recent study published in PLOS Biology found that individuals with strong attitudes towards science tend to be overconfident about their level of understanding. This suggests that addressing the discrepancy between what people know and believe they know may be a more effective strategy for improving scientific literacy.

SourcePLOS·JournalPLOS Biology·TypeObservational study·DateJan 24, 2023

New tropical kelp forest discovered in the Galapagos Islands

A new species record of mesophotic kelp was discovered in the Galapagos Islands, characterized by its extensive and dense kelp forest at depths of ~50m. The research highlights the importance of these forests as ecosystem engineers and supports for marine life, with potential implications for carbon sequestration.

SourceUniversity of Malaga·JournalMarine Biology·TypeExperimental study·DateJan 17, 2023

A plethora of plant molecules provides a ple"flora" of data

A searchable library of 1,600 chemically-diverse plant extracts has been established, providing valuable insights into plant metabolites' roles in drug development. The library shares both data and methods, making it an exceptional resource for advancing chemodiversity digitization.

SourceGigaScience·JournalGigaScience·TypeExperimental study·DateJan 17, 2023

OB-GYN research lacks racial, ethnic inclusivity

A new Northwestern Medicine study found that all U.S. OB-GYN subspecialties lack racial and ethnic representation in clinical trials and research publications. This absence has negative consequences, including biased tools for diagnosing endometrial cancer and unacceptably low sensitivity in the Black female population.

SourceNorthwestern University·JournalJAMA Surgery·DateDec 21, 2022