Researchers from Project Seahorse analyzed 7,794 validated iSeahorse observations from 96 countries, revealing new information on sex ratio and pregnancy seasonality. The study found that many seahorse species have larger geographic ranges, more diverse habitats, and shallower depth ranges than previously known.
A study by NTU Singapore researchers found that cool paint coatings can reduce city heat by up to 2 degrees Celsius, improving pedestrian thermal comfort levels. The coatings reflected sunlight and absorbed less heat, resulting in cooler temperatures and reduced indoor air-conditioning energy consumption.
A recent study published in JAMA found that Black patients are less likely to receive a heart transplant than white patients, with odds of acceptance being higher for white candidates. The study also revealed that the intersection of race and gender often worsens access for Black women.
Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins. The study identified over 600 new effector proteins that could be used therapeutically, including those that can efficiently degrade or stabilize target proteins.
Researchers discovered a new treatment that strengthens muscles in patients with Myasthenia Gravis, an autoimmune disease leading to severe weakness and fatigue. The breakthrough, targeting the connection between nerves and muscle cells, shows promising results without significant side effects.
Research reveals a significant connection between oral bacteria and accelerated pancreatic cancer development in mice. Viable Porphyromonas gingivalis was found in the pancreas of healthy mice after gum application, causing changes in the organ's microbial balance.
A new measure called “outdoor days” describes the number of days per year that outdoor temperatures are neither too hot nor too cold for people to go about normal outdoor activities. This measure reveals significant global disparities, with the North gaining more outdoor days and the South losing them due to rising temperatures.
The fungus C. albicans uses both yeast and hyphae forms to colonize the intestine efficiently when a complex bacterial community is present. The hyphal form produces Candidalysin, which inhibits bacterial metabolism, giving the fungus a competitive advantage.
Researchers have discovered a new immunotherapy approach to overcome resistant leukemia by targeting the mutated TP53 gene. Combining pharmacological therapies with genetically engineered CAR T-cells increases effectiveness against cancer cells, offering promising strategies for patients with resistant disease.
Researchers at Xi'an Jiaotong-Liverpool University developed a new method that enables the efficient production of cysteine-rich peptides and microproteins in their naturally folded 3D structure. The approach uses organic solvents to mimic nature's oxidative folding process, resulting in speeds of over 100,000 times faster than aqueous...
A recent discovery reveals that the natural molecule trigonelline can increase NAD+ levels and improve muscle function during ageing. Lower levels of trigonelline were found in older people with sarcopenia, a condition where muscles weaken and mass is lost.
A Mayo Clinic study found that microglia shield neurons from the aftereffects of anesthesia, enhancing and boosting neuronal activity to awaken the brain. This discovery could lead to new treatments for post-anesthesia delirium and hyperactivity.
Researchers analyzed large craters on Europa to determine the ice shell's thickness, finding it to be at least 20 kilometers thick. This conclusion is based on the study of impact cratering and the combination of physical characteristics that could have created such a surface structure.
A team of researchers decoded the origins and spread of the bottle gourd, a staple in ancient civilizations for over 10,000 years. The study mapped the genetic blueprint of 197 varieties, revealing its domestication in Southern Africa around 12,000 years ago.
A team of citizen scientists, including local students, discovered a new beetle species in the Ulu Temburong forest. The newly described Clavicornaltica mataikanensis is one of the largest known relatives among its tiny flea beetle cousins, highlighting the need for further research on their ecology and diversity.
Research reveals that FoxO6 upregulates ApoC3, leading to increased lipid accumulation and liver damage in aged rats on a high-fat diet. The study suggests that targeting this pathway may offer therapeutic strategies against hepatic steatosis.
Research suggests that early-life tobacco exposure significantly increases the risk of developing Type 2 diabetes in adulthood, particularly for individuals with a high genetic risk. Lifestyle factors such as diet, exercise, and smoking habits may modify this risk, emphasizing the importance of healthy lifestyle choices.
Preliminary research suggests that short-term heat exposure can lead to increased inflammation and impaired immune function, making individuals more susceptible to infections. Adults older than 60 and those with existing cardiovascular disease are particularly at risk.
Scientists at the University of Vienna identified a significant error in calculating temperature extremes, leading to an underestimation of heat days. The mistake stems from incorrect application of moving time windows, which can reduce the probability of extreme events.
A Clemson astrophysicist's research offers the most stringent constraints yet on dark matter's fundamental nature. The study reveals a small hint of a signal that could be confirmed in the next decade if real.
Scientists discovered an immune cell protein that can target and destroy fibrolamellar carcinoma, a rare liver cancer with a poor prognosis. T-cell therapy may effectively treat the disease by recognizing the fusion protein, providing a novel approach for FLC treatment.
Researchers have identified a potential path to eliminate the viral reservoir that prevents people from being completely cured of HIV. A new drug candidate, called a proteolysis targeting chimeras (PROTAC) molecule, triggers the degradation of the Nef protein, which suppresses HIV replication and restores immune system detection. This ...
Recent medications for Type 2 diabetes and weight loss have positive effects on cardiovascular and kidney health but are not always prescribed or accessible to those who need them. The studies highlight the need to address barriers to access and equity, particularly among Black adults with severe obesity.
Researchers at MIT and University of Helsinki discovered a protein in human sweat that can protect against Lyme disease. A genetic variant of this protein is associated with increased susceptibility to the disease.
Scientists have developed a new method to manipulate light using synthetic dimension dynamics, enabling precise control over light propagation and confinement. This breakthrough has significant implications for applications such as mode lasing, quantum optics, and data transmission.
Researchers have identified a potential therapeutic target for Borjeson-Forssman-Lehman Syndrome, a neurodevelopmental disorder characterized by seizures and intellectual disability. The study found that PHF6 gene mutations impair Ephrin receptor regulation, leading to neural stem cell misregulation.
A new study by Uppsala University researchers demonstrates that heteroresistance, a common transient resistance in bacteria, can facilitate the development of antibiotic resistance. The study found that heteroresistant bacteria carrying more resistance gene copies result in slower growth and increased risk of treatment failure.
The American Society for Biochemistry and Molecular Biology's annual meeting features exciting research findings on antibacterial compounds, whooping cough infection, nicotine addiction, and more. Complementary on-site press passes will be issued to a limited number of attendees.
New research reveals spent coffee grounds can act as an efficient adsorbent of bentazone, a highly neurotoxic herbicide. Activated carbon from spent coffee grounds showed a 70% efficiency in bentazone removal and high sensitivity to pollutants.
Researchers have identified a gene responsible for the development of starvation-induced fatty liver in cavefish, which are able to protect their liver due to reduced fat accumulation. This genetic basis has implications for understanding and addressing liver conditions in humans, including Type 2 diabetes and obesity.
A new multitasking substance has been identified to prevent and treat both flu and COVID-19 infections concurrently. The long-acting recombinant cytokine protein rhIL-7-hyFc demonstrated therapeutic and preventive effects against various respiratory diseases, including COVID-19, influenza virus, and respiratory syncytial virus.
Researchers developed an improved method for G4 landscape determination, revealing that sequence property-specific constraints in the nuclear environment mitigate G4 formation. The technique, AbC G4-ChIP, captures G4s efficiently without bias, showing that depletion of a repeat-binding protein enhances net G4 capture at specific sites.
A study led by Leopold Eckhart found that the genetic programme controlling keratinized claws originated in a common ancestor of humans and frogs. The research team used the tropical clawed frog as an experimental model and discovered that important hair components, including keratins, share similarities with human hair.
A new study has discovered that Streptococcus anginosus bacteria play a significant role in causing stomach cancer. The research showed that S. anginosus infection led to gastric inflammation, cell damage, and the growth of stomach cancer cells, doubling tumour size and weight in some cases.
Researchers identified nicotinamide adenine dinucleotide (NAD) as a key component of T cell receptor metabolic reprogramming, enabling rapid immune cell division. This discovery may lead to improved vaccine strategies and enhanced responses in cell-based therapies for cancer treatment.
Researchers found that gut bacteria in newborns produce serotonin, promoting the development of immune cells called Tregs. This helps prevent allergic reactions and autoimmune diseases. The study suggests that unique gut bacteria may supply neurotransmitters needed for critical biological functions during early development.
Researchers at Flinders University have discovered a bedtime nasal spray that can reduce the severity of sleep apnea in people and lower their blood pressure. The study found that the spray, which blocks potassium channels, improved oxygen levels and reduced markers of OSA severity in 7 out of 10 participants.
Researchers at UVA Health discovered a potential blood test to predict patients with severe COVID-19 who are likely to recover well and those at risk of long-term lung problems. The study found that patients with late-resolving symptoms had fewer immune cells in their blood, correlating with symptom severity.
Recent advancements in terahertz radiation reveal the physical processes involved in quantum materials. The study highlights the exploration of THz emission in topological insulators and semimetals, multiferroics, and superconductors, shedding light on their fundamental physics.
A potentially fatal parasite has been discovered in the Colorado River in California, affecting dogs and causing liver and intestinal illness. Researchers confirm the presence of Heterobilharzia americana, a flatworm that can be transmitted through snails and water, highlighting the need for awareness and precautions among dog owners.
A new study published in the journal Stroke found that African American veterans with PTSD had a significantly higher risk of re-hospitalization after a stroke compared to those without PTSD. This was not observed among white veterans. The study highlights the importance of targeted care for high-risk populations and reducing modifiabl...
Researchers have identified a subset of T-cells that acts like stem cells and continuously generates effector T-cells that attack transplanted organs. Targeting the transcription factor IRF4 may lead to innovative therapies for patients with chronic infections, cancers, autoimmune diseases and transplanted organs.
Researchers at UC San Diego discover that acute stress triggers a switch in neurotransmitters, leading to generalized fear responses. They also find that suppressing GABA production and using antidepressants can prevent this effect.
Researchers from the University of Kent have identified steroid drugs used for hormone replacement therapy that can stop the growth of antibiotic-resistant E. coli and effectively kill MRSA. These findings suggest an alternative to conventional antibiotics, providing a potential solution to the growing threat of antibiotic resistance.
Communications of the ACM has been revamped as a web-first, open-access publication, enabling rapid article publication and enhanced reader experience. The new model aims to increase engagement with the broader computer science community, expand author reach, and showcase cutting-edge ideas and research.
A new rapid test for melioidosis uses CRISPR technology to detect the genetic target of Burkholderia pseudomallei with 93% sensitivity. The test can diagnose patients in hours, allowing health professionals to prescribe the correct antibiotics faster and potentially saving lives.
Researchers developed ultra-thin defect-free semiconducting fibers, over 100 meters long, which can be woven into fabrics. The fibers demonstrate excellent electrical and optoelectronic performance, enabling various applications such as wearable electronics and sensors.
Researchers at Mass General Cancer Center have achieved dramatic tumor regression in glioblastoma patients after receiving next generation CAR-T therapy. The treatment, known as INCIPIENT, combines two forms of therapy to target mixed cell populations within tumors.
Researchers discover that certain bacteria can evade the immune system by circumventing antibody coating, leading to severe inflammation. The study identifies IgG2 as a key player in this process, providing potential biomarkers and targets for new treatments.
The ACMG Foundation for Genetic and Genomic Medicine has presented seven Next Generation fellowship awards to promising early career professionals in medical genetics and genomics. The recipients include Xueyang Pan, Bianca Seminotti, and Adriel Yejin Kim, who will support their research projects with corporate donations from Pfizer, S...
Researchers deciphered a novel process helping viruses choose to be nasty or friendly to their host bacteria. Phages use the bacterial immune system to make decisions, activating violent mode when necessary.
Researchers found that secreted products from certain bacteria strains can reduce inflammation in gut-derived cell lines and improve airway health in mice with cystic fibrosis. The study suggests probiotics could be beneficial for kids with CF, providing a potential proof of concept.
Researchers at UNIST have unveiled a new principle of motion in liquid crystals, where objects can move in a directed manner by changing their sizes periodically. The discovery has far-reaching implications for the development of miniature robots and advances research in complex fluids.
Researchers create a technique using prime editing to quickly and easily screen cancer genes, revealing new information on p53 mutations. The method allows for the analysis of over 1,000 different mutations in the tumor suppressor gene p53, which are seen in more than half of all cancer patients.
Research by Johns Hopkins Medicine suggests that increased stiffness in aging skin contributes to higher rates of melanoma metastasis by stimulating blood vessel growth and making them leaky. Treating older mice with drugs blocking ICAM1 prevented these changes, shrinking tumors and reducing metastasis.
Researchers at Aarhus University have found a way to spot Alzheimer's disease before it develops into dementia using an advanced blood test analysis. The study suggests that activating the body's immune system at an early stage of the disease may slow down its progression.
Researchers developed a wearable device for non-invasive monitoring of hemodynamic indicators like heart rate, blood pressure, and oxygen saturation. The photoacoustic imaging watch offers valuable insights into disease diagnosis and treatment.
Researchers at UVA Health System have discovered genetic clues that may help identify people at risk of cardiovascular disease, including atherosclerosis. The study identified 20 locations on chromosomes that influence protein production, shedding light on why smooth muscle cells sometimes are beneficial and sometimes harmful.
Researchers found that different areas of the brain start with a similar organization in early development, using a shared blueprint to guide neural growth. This suggests that neurodevelopmental disorders may act similarly across diverse brain areas.
A new study suggests that mushroom extract containing psilocybin demonstrates superior efficacy in stimulating neuroplasticity and promoting new connections between nerve cells. The research found that the extract had a more potent and prolonged impact on synaptic plasticity compared to chemically synthesized psilocybin.