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High mortality for hospital referred Malawian children with low glucose or blood oxygen levels

A study in rural Malawi found high mortality rates for children admitted to hospital with low blood sugar or oxygen levels. The findings suggest that earlier identification and prompt care-seeking could help reduce the risk of death, emphasizing the need for better clinical management of severely ill children.

SourceKarolinska Institutet·JournalBulletin of the World Health Organization·DateApr 29, 2022

Analysis of firearm violence during pandemic in US

During the first year of the COVID-19 pandemic, firearm-related incidents and nonfatal injuries increased significantly in all 50 states and the District of Columbia. The analysis found a notable association between the pandemic and firearm violence, highlighting the need for further research and interventions to address this issue.

SourceJAMA Network·JournalJAMA Network Open·DateApr 28, 2022

US study in over 850,000 patients hospitalized with COVID-19 underscores need for improvement in therapeutic approaches for critically ill

A large nationwide study of 853,219 COVID-19 patients found that all-cause mortality rates remained unchanged at 16%, while survival improved for most levels of disease severity. However, ICU use and mortality rate increased for critically ill patients on invasive mechanical ventilation or ECMO.

Women and lower-income patients have higher rates of death after heart surgeries

A study published in The Journal of Thoracic and Cardiovascular Surgery found that female patients and those from lower-income neighborhoods have higher mortality rates following cardiovascular and thoracic procedures. Patients in these groups also experienced higher comorbidity burdens, urgent admissions, and poorer health outcomes.

SourceBrigham and Women's Hospital·JournalJournal of Thoracic and Cardiovascular Surgery·DateApr 22, 2022

Opioid-related deaths affecting more younger adults, study finds

A new study found that opioid-related mortality rates in Ontario, Canada, have shifted downward to peak in the mid-30s among males and females. The study analyzed high-frequency data from 2003 to 2020 and hypothesizes that opioid-related mortality among younger adults will continue to grow.

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateApr 20, 2022

Mental illness associated with increased death from cardiovascular disease

A systematic review and meta-analysis of 108 studies found that people with severe mental illness, including schizophrenia, have twice the cardiovascular-related mortality rate as the general population. The association has grown stronger over recent decades, with a possible link to changes in antipsychotic use and smoking prevalence.

SourcePLOS·JournalPLOS Medicine·TypeSystematic review·DateApr 19, 2022

New Chinese Medical Journal study assesses mortality risk in multimorbid patients

A new study published in the Chinese Medical Journal assessed mortality risk in middle-aged and older Chinese individuals with multiple diseases. The study identified four multimorbidity patterns, with cardiometabolic being the most common, and found that individuals with these patterns had a significantly increased mortality risk.

SourceCactus Communications·JournalChinese Medical Journal·TypeObservational study·DateApr 13, 2022

Adolescent drug overdose deaths rose exponentially for the first time in history during the COVID pandemic

Adolescent drug overdose deaths nearly doubled in 2020 and rose another 20% in early 2021 compared to the 10 years prior, despite stable drug use rates. The increase is largely attributed to illicit fentanyls found in counterfeit pills, which can be deadly if ingested.

SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA·TypeData/statistical analysis·DateApr 12, 2022

Pulse oximeters did not change outcomes for patients in COVID-19 monitoring program

A randomized trial by the University of Pennsylvania School of Medicine found that pulse oximeters did not change outcomes for patients with COVID-19 in a remote monitoring program. The study enrolled over 2,000 patients and found no statistical difference in the average number of days patients spent alive and out of the hospital.

SourceUniversity of Pennsylvania School of Medicine·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateApr 6, 2022

New OHIO study finds link between racial/ethnic disparities and COVID-19 deaths

A new study published in Ethnicity & Disease found that residential segregation and systemic racism are associated with negative outcomes for Black and white Americans, disproportionately impacting Black residents. The study analyzed data from every state, finding higher death rates among Black individuals in segregated areas.

SourceOhio University·JournalEthnicity & Disease·TypeData/statistical analysis·DateMar 10, 2022

Hurricanes and other tropical cyclones linked to rise in U.S. deaths from several major causes

A landmark study published in JAMA reveals that hurricanes and tropical cyclones in the US are associated with increased deaths from various causes, including injuries, infectious diseases, and cardiovascular conditions. The study analyzed 33.6 million death records and found a significant increase in mortality rates after tropical cyc...

Study identifies virus responsible for high mortality rate among pigeons in São Paulo City

A study found that a subtype of Newcastle disease virus caused the deaths of dozens of pigeons in São Paulo City. The researchers sequenced the viral genome and identified tissue wounds to determine the cause of death, revealing subgenotype VI.2.1.2 as the responsible pathogen. The risk to humans and poultry is considered low.

Geisel study finds higher death rates in older adults with cognitive impairment during the Pandemic

A new study by Dartmouth's Geisel School of Medicine found higher mortality rates among older adults with cognitive impairment during the COVID-19 pandemic. The study showed a 24% increase in mortality for individuals with Alzheimer's disease and a 36% increase for nursing home residents with ADRD.

SourceThe Geisel School of Medicine at Dartmouth·JournalJAMA Neurology·TypeObservational study·DateFeb 28, 2022

Colon cancer screening can erase disparities in outcomes

A regionwide, structured colorectal cancer screening program eliminated disparities in colorectal cancer death rates between Black and white Kaiser Permanente members. Organized screening outreach markedly increased screening rates and led to significant decreases in incidence and death rates.

SourceKaiser Permanente·JournalNew England Journal of Medicine·DateFeb 23, 2022

Brazilian babies born with Zika virus syndrome at greater risk of death in first three years of life than those born without

A new study published in the New England Journal of Medicine found that babies born with Congenital Zika Syndrome are at an 11x greater risk of dying during their first three years of life compared to those born without. The study highlights the importance of protecting women, especially those pregnant or of child-bearing age, against ...

SourceLondon School of Hygiene & Tropical Medicine·JournalNew England Journal of Medicine·DateFeb 23, 2022

UTSA collaborative study with DoD and VA aims to heighten awareness, improve care for veterans with traumatic brain injury

A UTSA-led study found that post-9/11 military veterans with traumatic brain injury (TBI) are at higher risk of chronic disease, mortality, and mental health issues compared to the general population. The study estimates excess deaths among a large cohort of veterans and highlights the need for better methods of intervening.

SourceUniversity of Texas at San Antonio·JournalJournal of the American Medical Association·DateFeb 17, 2022

India may have experienced 3.2-3.7 million COVID-19 deaths to date, one of the highest death tolls, according to new model using alternative data sources to address underreporting

A new model estimates India's actual COVID-19 death toll could be as high as 3.2-3.7 million, surpassing other reported figures. This revised estimate aims to address the issue of underreporting and provides a more accurate representation of the pandemic's impact on India.

SourcePLOS·JournalPLOS ONE·DateFeb 16, 2022

Simultaneous use of non-benzo sleeping pills and anti-epilepsy drugs – gabapentinoids-- increases drug overdose deaths

Researchers found a significant increase in overdose deaths involving gabapentinoids and z-drugs between 2000 and 2018. The proportion of deaths increased by more than three-fold, coinciding with exponential prescription increases. Co-usage with opioids was common, with over 67% of overdose victims having both substances in their system.

SourceColumbia University's Mailman School of Public Health·JournalThe Lancet Regional Health - Americas·DateFeb 16, 2022