Articles tagged with Memory Disorders
New research published in JNeurosci reveals that impaired cognition can be part of normal aging, rather than an early sign of Alzheimer's. Cognitively frail adults showed brain structure and activity similar to healthy controls, suggesting lifestyle factors like physical activity and education may play a role.
Automated brain volumetry in memory-impaired patients shows significant differences and systematic biases between conventional and ultrafast 3D T1-weighted MRI sequences. Most regions demonstrated substantial agreement but also significantly different mean values and consistent biases.
A new clinical trial is enrolling young people with rare genetic mutations that cause early-onset Alzheimer's disease. The study will test gantenerumab to prevent the buildup of toxic protein amyloid beta, which can slow or stop the disease.
Researchers have discovered the Apterous protein's crucial role in retaining memories through its interaction with the Chi cofactor and regulation of neurotransmitters. In fruit flies, Ap plays a double role in long-term memory consolidation, highlighting potential new treatment approaches for memory-related disorders.
Researchers found damage to a brain part that regulates hyperactivity contributes to both memory issues and seizures in the most common form of epilepsy. This discovery may lead to earlier diagnosis and new treatments for epilepsy and related disorders.
Researchers discovered that eliminating α-endosulfine (ENSA) or blocking its function reduces brain changes and improves memory in mice. ENSA blocks a potassium channel, which, when blocked, combats excess ENSA levels associated with Alzheimer's disease.
Researchers found that participants with moderate dementia performed better in cluttered environments, while those with mild and severe dementia showed no significant difference. The study suggests that adapting physical environments to suit individual needs may be more effective than de-cluttering in supporting people with dementia.
Researchers at the University of Ottawa have made a breakthrough in reversing memory deficits and slowing disease progression in female mouse models of Alzheimer's disease. The study found that activating a specific receptor was effective in treating females, who make up two-thirds of diagnosed cases.
Researchers have found that stimulating the anterior thalamus can increase memory-related brain activity and restore memory function in rats with MTT lesions. The study suggests that therapies targeting this region could help recover memory in patients with brain injury, challenging previous notions of memory recovery.
A long-term study has revealed that drinking higher amounts of coffee may make you less likely to develop Alzheimer’s disease. The study found an association between coffee and several important markers related to Alzheimer’s disease, including executive function and amyloid protein accumulation in the brain.
New research found that physical activity is linked to lower microglial activation, a key factor in Alzheimer's disease pathology. The study, published in JNeurosci, suggests that exercise may help reduce inflammation and improve cognitive aging in older adults with more severe AD pathology.
A new study shows that older adults with mild dementia can improve their daily task completion using digital voice recorder apps and reminder apps. Greater usage of these apps is associated with better memory and greater improvements in activities of daily living.
A new Rutgers study finds that mindfulness therapy through mobile app Mindfulness Coach reduces symptoms of anxiety, stress, and depression in caregivers. The study suggests that mHealth interventions can positively impact future mental health treatment options for patients.
Researchers found that glatiramer acetate improved cognitive behavior and reduced amyloid plaques in a mouse model of Alzheimer's disease. This study suggests therapies targeting the immune system could be effective in treating the disease.
Researchers uncover how sensory inputs and cognitive processes interact in the brain to create our perception of the world. The study explores the neural basis of perceptual phenomena, shedding light on disorders like ADHD, autism, and Alzheimer's disease.
A new study from the University of Eastern Finland found that working-age people living with dementia experience insufficient guidance and counselling. This results in premature retirement and loss of social contacts, leading to feelings of anxiety, exhaustion, and shame.
Researchers discovered a significant impact on executive functioning, processing speed, and memory encoding in patients treated for COVID-19. Cognitive impairments persisted several months after the initial infection.
A pilot study found improvements in memory, motor function, and processing skills in healthy individuals after receiving transcranial photobiomodulation therapy. The therapy, involving infrared light, has the potential to alleviate nerve cell damage and reduce symptoms of dementia.
A study in rats found that a diet of highly processed foods led to inflammation and behavioral signs of memory loss in the brain. Supplementing with omega-3 fatty acid DHA prevented these effects almost entirely. The study suggests that limiting processed foods and increasing DHA consumption may help prevent rapid memory decline in old...
The Baycrest-developed Cogniciti Brain Health Assessment is as accurate as the Montreal Cognitive Assessment (MoCA) in identifying problems with memory and attention, but outperforms MoCA in detecting subtle cognitive decline. The self-administered online assessment can provide important information for clinical assessment of memory an...
Researchers have discovered a protein called "shank" that acts as a biomarker for modifiable memories. This discovery may lead to the development of new treatments for Post-Traumatic Stress Disorder (PTSD) by identifying factors that make memories susceptible to change.
Researchers comprehensively review T-cell responses to respiratory viral infections and chronic obstructive pulmonary disease (COPD), highlighting key characteristics of peptide-reactive T-cells. The review aims to improve understanding of the underlying mechanisms, leading to more effective immune protection and treatment methods.
A study published in Communications Biology reveals that chronic hyperglycemia in diabetes impairs working memory performance by altering the connection between key brain regions. Researchers found that areas critical for forming and retrieving memories were over-connected, leading to errors in remembering correct information.
Researchers at Mount Sinai Hospital are testing a novel light therapy to slow Alzheimer's debilitating effects, aiming to improve both cognition and sleep. The treatment involves flashing pulses of light designed to enhance electrical brain waves and reset the sleep-wake cycle.
A study of over 2,000 European retirees found that internet usage after retirement is associated with better cognitive scores. Specifically, female retirees who regularly surfed the internet recalled more words on a word recall test compared to their non-internet-using counterparts.
A pioneering EEG test has shown high effectiveness in detecting small changes in brain waves associated with memory recall. The passive test could lead to earlier diagnosis and treatment of Alzheimer's disease, potentially improving patient outcomes.
A two-hour glucose tolerance test is linked to cognitive decline in a 10-year follow-up study. Higher blood glucose levels measured in the test were associated with weaker performance in a memory test and a greater decline in results.
A Bristol-led research team has identified specific receptors for the neurotransmitter acetylcholine that re-route information flowing through memory circuits in the hippocampus. The discovery holds promise for developing new, safer treatments for conditions like Alzheimer's disease and schizophrenia.
Researchers at the University of Helsinki have identified two distinct patterns of alpha-synuclein accumulations in the olfactory bulb, associated with differing disease types of dementia with Lewy bodies. These findings support the classification of the disease into two distinct forms, one progressing to the amygdala and another to th...
A new study highlights significant disparities in dementia care availability by gender, race, ethnicity, education level, and family structure. The findings emphasize the importance of family caregivers, with those having available spouse or adult child support being less likely to move into nursing homes.
A recent study found that fine particle pollution, specifically PM2.5, may contribute to the disproportionate number of African American women affected by dementia. Despite adjusting for various risk factors, Black women still had double the risk of developing Alzheimer's disease compared to white women.
Chronic light exposure disrupts circadian rhythms in rats, leading to memory deficits and amyloid β accumulation similar to Alzheimer's disease. Fluoxetine treatment prevents these effects, suggesting a potential therapeutic strategy.
Researchers at UC San Diego have discovered the main components driving amyloid beta-associated synapse degeneration in Alzheimer's disease. They found that blocking a toxic signaling pathway can protect synapses and preserve cognitive function, offering a potential therapeutic agent.
Researchers found a significant increase in self-reported memory issues among COVID-19 patients with mild disease, compared to controls. Eight months post-infection, the prevalence of memory problems was higher in this group than in untested controls or those with negative test results.
Researchers at the University of Cambridge and University of Leeds successfully reversed age-related memory loss in mice by manipulating the extracellular matrix of the brain. By restoring the balance of compounds known as chondroitin sulphates, they were able to restore neuroplasticity and alleviate memory deficits.
Researchers identified egocentric bearing cells in the parahippocampal cortex, which encode spatial information on a mental map centered on each person. These cells play a role in both navigation and memory, particularly in processing spatial information of memories.
A recent study published in Cell Reports found that KIF5C plays a critical role in long-term memory formation by transporting RNA cargo to synapses. The research suggests that impairments in KIF5C could contribute to neurological disorders, such as intellectual disability and autism.
A novel study of high-potency cannabis found memory impairments related to free recall, source memory, and false memories. However, vaping high-potency concentrates showed comparable performance to smoking low-potency flower, suggesting cautious optimism for the little-studied product.
Researchers at Kumamoto University discovered that muscles and satellite cells retain positional memory from fetal life, based on the expression pattern of the homeobox (Hox) gene cluster. This finding is expected to provide insights into the pathogenesis of muscle diseases and develop regenerative medicine.
A group of older adults called 'superagers' have been found to maintain the same level of neural differentiation as young adults, enabling them to create distinct representations of visual information and accurately recall image-word pairs. This study used fMRI to understand how superagers learn and remember new information.
Researchers at UCLA discovered that virtual reality environments strengthen theta waves, a key brain rhythm for learning and memory, in rats. This finding could lead to new treatments for disorders like ADHD, Alzheimer's disease, and depression.
A study published in Nature Medicine found that over 50% of young adults with mild to moderate COVID-19 developed persistent symptoms six months later. These symptoms included impaired memory, concentration difficulties, fatigue, shortness of breath, and loss of smell or taste.
A recent study found that minority groups in the US are more likely to experience cognitive issues earlier in life. The study analyzed data from over 179,000 adults and found that Black and Hispanic individuals were more likely to self-report memory loss and cognitive decline compared to white individuals.
Researchers have discovered a link between ADORA2B protein in red blood cells and age-related cognitive decline. The study found that mice lacking ADORA2B exhibited accelerated aging, including poor memory and hearing deficits.
Researchers studied rats in mazes to observe brain cell activation during correct and incorrect memory recall. They found similar patterns of cell activation, but with different timing and energy levels, suggesting a link between memory disorders like Alzheimer's and faulty retrieval.
Researchers found that memories become less vivid with age, but retain meaningful semantic elements. Frequent recalling boosts 'gistification' of memories, making them more concept-based. The study has implications for understanding post-traumatic stress disorder and eyewitness testimony.
Researchers from the Netherlands Institute for Neuroscience have discovered a small molecule that can be used to rejuvenate the brain and counteract memory loss in Alzheimer's disease. The molecule, microRNA-132, regulates adult hippocampal neurogenesis and is required for the neurogenic process in the adult hippocampus.
A simple diagnostic tool has been developed to predict the individual risk of developing Alzheimer's disease with over 90% accuracy. The algorithm combines data from a simple blood test and brief memory tests, and has been shown to be significantly more accurate than clinical predictions by dementia experts.
Researchers propose sensory referenced suppression theory, where brain corrects for changes in sensory input to isolate familiar activation. This could have implications for treating memory-impairing diseases like Alzheimer's and developing AI systems that work similarly to human brains.
A TGen-led study of 70,000 individuals found that both smoking and cardiovascular disease impair verbal learning and memory in adulthood, with sex differences observed. The study suggests that quitting smoking can improve brain function and maintaining cardiovascular health is crucial for preventing cognitive decline.
A new study reveals that people often forget their preferred options and choose less-preferred ones due to imperfect memories. Researchers used fMRI scans and decision-making experiments to understand how memory impacts decisions.
Researchers have identified a neurologic pathway that explains how non-damaging brain impacts cause long-term problems with learning and memory. A new treatment approach may reactivate and normalize cognitive function.
A new online application, Living Memory Home, offers a virtual and personal memorial space for mourners to deposit memories and feelings about their loss. The platform allows users to create a customized memorial space, share photos and messages, and reflect on both positive and negative memories and emotions.
Scientists have found that a Mediterranean-like dietary pattern with high intake of vegetables, legumes, and fish may reduce protein deposits in the brain and prevent brain atrophy. The study suggests that adhering to this diet could lower the risk of Alzheimer's disease and dementia.
Researchers used gene therapy to introduce a therapeutic compound into the hippocampus of AD mice, preserving learning and memory. The approach restored normal neural function and reversed neurodegenerative processes by promoting neuronal and synaptic plasticity.
A team of scientists at IBEC and Stanford University reveals that the brain's ability to autonomously learn reflects nature more closely than previously thought. This discovery has implications for improving memory deficits in humans and building new AI systems with advanced memory capabilities.
A team of scientists at Baycrest's Rotman Research Institute is investigating the effects of prior knowledge on learning and memory in bird experts. Using functional magnetic resonance imaging (fMRI) and electrical currents, they aim to determine whether a similar process takes place in the human brain.
A new study published in PLOS Genetics found that lithium can improve fear memory and hippocampal neurogenesis in mice with symptoms similar to Bardet-Biedl Syndrome. The researchers suggest that this may be an effective treatment for intellectual disability caused by the disorder.
A shared set of brain regions play an important role in controlling the successful retrieval of weak memories, according to a new University of York study. The research may have implications for treating memory disorders like dementia and developing more advanced artificial intelligence systems.
Texas A&M researchers have developed a method to indirectly retrieve and weaken fear memories, which could lead to more effective therapy for treating trauma. By reactivating traumatic memories through conditioning procedures, scientists can make them vulnerable to disruption.