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TGen-led study of 70,000 individuals links dementia to smoking and cardiovascular disease

A TGen-led study of 70,000 individuals found that both smoking and cardiovascular disease impair verbal learning and memory in adulthood, with sex differences observed. The study suggests that quitting smoking can improve brain function and maintaining cardiovascular health is crucial for preventing cognitive decline.

SourceThe Translational Genomics Research Institute·JournalScientific Reports·DateMay 13, 2021

Altering traumatic memories

Texas A&M researchers have developed a method to indirectly retrieve and weaken fear memories, which could lead to more effective therapy for treating trauma. By reactivating traumatic memories through conditioning procedures, scientists can make them vulnerable to disruption.

SourceTexas A&M University·JournalNature Neuroscience·DateApr 8, 2021

Riding the wave to memory-forming genetics

Researchers found 300 genes associated with neural oscillations, including hub genes that control separate gene networks. Surprisingly, several of these hubs were active in glial cells, which support and protect nerve cells. This discovery provides an entry point for further research into the underpinnings of human memory.

SourceUT Southwestern Medical Center·JournalNature Neuroscience·DateMar 10, 2021

Why odors trigger powerful memories

Researchers at Northwestern University discovered a neural basis for how odors elicit powerful memories, with the olfactory areas connecting directly to the hippocampus. The study suggests that the sense of smell retains direct access to the hippocampus, unlike other senses like vision and hearing.

SourceNorthwestern University·JournalProgress in Neurobiology·DateMar 8, 2021

Does air pollution affect mental health later in life?

A study of women aged 80 found a significant association between air pollution exposure and increased depressive symptoms. Long-term exposure to nitrogen dioxide or fine particulate air pollution was linked to small but notable effects on depressive symptoms.

SourceWiley·JournalJournal of the American Geriatrics Society·DateNov 18, 2020

Can memory manipulation help treat alcohol addiction?

Researchers at Boston University used optogenetics to study the effects of alcohol on brain function and behavior. They found that artificially dampening fear responses in mice could mitigate addiction-related behaviors. This suggests that memory manipulation may be a promising approach to treating alcohol addiction.

SourceBoston University·JournalHippocampus·DateNov 18, 2020

Social novelty has a special place in the brain

Researchers at RIKEN Center for Brain Science discovered a brain region called the SuM that detects new social experiences and segregates them from unfamiliar places. This finding can help understand normal memory and conditions where recognizing new information is impaired.

SourceRIKEN·JournalNature·DateSep 30, 2020

Memory protein

A study by UC Santa Barbara researchers found that a disordered protein exhibits slow relaxations, defying expectations, and 'remembers' its previous stretching. This behavior is similar to glassy materials like memory foam and crumpled paper.

SourceUniversity of California - Santa Barbara·JournalPhysical Review Letters·DateAug 25, 2020

New molecule reverses Alzheimer's-like memory decline

A new study published in Redox Biology shows that the drug CMS121 successfully reversed memory loss in a mouse model of inherited Alzheimer's disease. The drug works by normalizing lipid peroxidation and lowering levels of fatty acid synthetase, suggesting FASN as a potential target for treating Alzheimer's disease.

SourceSalk Institute·JournalRedox Biology·DateAug 4, 2020

Older adults share fewer memories as they age

A new study suggests that older adults spontaneously share fewer memories of their past experiences, with less detail in descriptions. Researchers analyzed daily conversations using a smartphone app and found this decline to be age-related, possibly linked to brain changes.

SourceUniversity of Arizona·JournalFrontiers in Human Neuroscience·DateJun 29, 2020