Cases of children ingesting magnets led to a quintupling of incidents between 2002 and 2011. Ingestion of multiple magnets resulted in more severe outcomes, including emergency surgery.
Researchers at Ohio State University Comprehensive Cancer Center discovered that the tumor-suppressor gene A20 is silenced due to the loss of microRNA-29, leading to increased levels of NF-kB and tumor progression. This finding could guide the development of more effective therapies for soft-tissue sarcomas.
A study found cisplatin-induced ototoxicity in mice is mediated by calpain 1 and 2, particularly calpain 2. Calpain's role suggests potential for clinical prevention and treatment strategies to mitigate deafness caused by cisplatin.
A protein involved in nerve-cell migration is implicated in the spread of brain cancer, according to new research from the University of Illinois at Chicago. The study found that cadherin11 promotes cancer cell migration and invasion by regulating cell adhesion and movement.
Researchers found that full activation of a crucial brain-signaling molecule requires coordinated motion of its segments. The study may reveal additional drug-binding sites on the receptor, aiding the development of drugs for conditions like epilepsy and Parkinson's disease.
Researchers found that people with sleep apnea are at a significantly higher risk of developing open-angle glaucoma compared to those without the condition. The study recommends clinicians alert patients about this association to encourage treatment.
Researchers at MIT and Max Planck Institute have mapped the wiring diagram of a tiny patch of mouse retina using a combination of human and artificial intelligence. They identified 950 neurons, including a new type of retinal cell, and classified most of them based on their connections with other neurons.
NASA's Aqua satellite captured infrared data showing very cold cloud top temperatures of strong thunderstorms around Tropical Storm Mangkhut's center before landfall in northern Vietnam. The storm is expected to dissipate within 24 hours after making landfall about 65 miles south of Hanoi.
Researchers used computer simulations to demonstrate that ice-age/warm-period interchange depends on the alternating influence of continental ice sheets and climate. The team found that large-scale glaciation alters sea levels and ocean currents, affecting the climate.
Researchers have identified a biomarker called ST2 that can predict the risk of graft-versus-host disease in stem cell transplant patients. Patients with high ST2 levels are more likely to experience severe immune responses and die within six months of the transplant.
Aristolochic acid, a plant compound in herbal remedies, causes upper urinary tract cancers through a distinct DNA mutational signature. The Johns Hopkins and Stony Brook study used whole-exome sequencing to identify this signature, which was found in 19 Taiwanese cancer patients exposed to the toxin.
Researchers found that a specific pattern in tumor pathology is strongly associated with cancer recurrence. Patients with this pattern are more likely to benefit from lobectomy and have a 75% lower risk of recurrence. The study may lead to new technology to precisely identify tumors with this pattern before surgery.
Using surface-enhanced Raman spectroscopy (SERS), scientists can distinguish between adult stem cells, enabling the use of healthy ones in therapies. This technique holds promise for advancing stem cell and other cell-based therapies to treat diseases like Parkinson's.
Researchers use NASA satellite data to track zebra movements and predict migration timing, revealing the importance of environmental cues. The study combines GPS tracking with satellite imagery and rainfall data to understand what drives animal migrations.
Brandeis researchers have discovered a previously unknown molecular temperature sensor in fruit flies, which belongs to a protein family responsible for sensing tastes and smells. The discovery provides insights into how insects respond to temperature and may help scientists develop more effective repellents or traps.
Researchers investigated brain activation during reading of Chinese characters with and without hand-radicals using fMRI. They found that characters with hand-radicals activated the right medial frontal gyrus, supporting embodied semantics theory.
The European Society of Cardiology's ESC Congress 2013 received a record number of abstract submissions, with nearly 10,500 entries. The congress will feature four Hot Lines press conferences, discussing innovative treatments for conditions such as venous thromboembolism and myocardial infarction.
A persistent high-pressure weather pattern contributed to the heat wave, which saw temperatures reach 32° Celsius in northern Siberia. The fires are burning in an unusual area, significantly north of the typical summer wildfire zone.
Researchers at Scripps Research Institute found a crucial molecular signal guiding brain development in the neocortex. The discovery may aid research on autism, schizophrenia, and other psychiatric conditions by understanding how molecules like reelin regulate neuron migration.
Researchers at UTSA and SwRI are developing a synthetic drug-loaded scaffold for bone grafting, which could improve treatment outcomes for patients with large bone defects. The scaffold would be scalable and include drug-microparticles that release active growth factors to promote bone cell formation.
Researchers found that controlling inflammation in the lower spinal cord is critical to the success of treadmill training after a spinal cord injury. Early training with minimal inflammation led to significant improvements in walking, lasting up to 42 days, while late training failed to produce similar results.
A new set of guidelines aims to reduce radical surgery and extend survival time for men with penile cancer, providing better quality of life. The guidelines offer various treatment options, including non-radical surgeries, laser therapy, radiation therapy, and radiochemotherapy.
A new study reveals that giant bacteria like Thioploca are invaded by anammox bacteria, which steal their nitrogen, leading to reduced algal growth and less food for marine organisms. This discovery may impact ocean productivity and have implications for fish life and fisheries.
A new two-minute assessment tool has been developed to help hospital staff identify patients at risk of developing delirium, a condition characterized by severe confusion and disorientation. The tool, termed AWOL, uses elements that can be assessed quickly in the fast-paced environment of a hospital.
A University of Oregon study reveals how librarians adapted to the Internet by redefining their occupational identity from expert knowledge to interpreting and connecting patrons with relevant information
A Penn study found that psoriasis patients with more severe skin disease are at higher odds of having major medical diseases, including lung disease, heart problems, and kidney issues. The researchers identified a common pathway involving TH-1 cytokines promoting inflammation and insulin resistance.
A study published in PLOS ONE found that dogs yawn contagiously and respond more frequently to their owner's yawns than a stranger's. The researchers suggest that this may be an emotionally connected behavior similar to humans.
A study in AIP Advances describes a muon imaging technique that could help assess damage within the reactor's core, locate melted fuel and potentially reduce radiation doses. The method uses naturally occurring muons to image dense objects, offering advantages over traditional muon imaging.
Recent research suggests that oxidative stress and mitochondrial damage are key contributors to the development of neurodegenerative diseases. The study highlights the importance of mitigating mitochondrial dysfunction as a potential therapeutic strategy for treating various neurodegenerative diseases.
A new system, nEmesis, uses machine-learning and crowdsourcing to analyze millions of tweets to find reports of likely food poisoning following a restaurant visit. The system ranks restaurants according to how likely it is for someone to become ill after visiting that restaurant.
A study of 60 older adults found that consuming two cups of hot cocoa per day for 30 days improved blood flow to the brain and enhanced working memory skills. The participants who started with impaired blood flow showed significant improvements in these areas, while those with regular blood flow showed no change.
Researchers found that plants can eavesdrop on herbivore cues, including snail slime, to mount a defensive response before being attacked. The study shows plants can use generalist herbivore cues in a sophisticated way to trigger defense mechanisms.
Researchers have discovered a key role played by TACC3-ch-TOG-clathrin in forming inter-microtubule bridges that stabilise kinetochore fibres during mitosis. Removing this protein team can induce cells to arrest and die, potentially providing a new approach to cancer treatment.
Research found that C-section infants had a narrower range of beneficial bacteria in their guts compared to vaginally delivered infants. This has implications for the development of their immune systems and risk of allergies. The study also found lower levels of Th1 chemical messengers, which can contribute to allergic diseases.
Scientists have developed a new way to predict turbulent flow near walls, which could reduce drag by 30% and save the global economy billions in fuel costs. This breakthrough has the potential to optimize vehicle performance and reduce emissions.
A Marshall University researcher has developed a technology for repairing skin injuries using nanotechnology. The $20,000 grant will help produce device prototypes and market the product to potential customers.
A large trial of nearly 3000 participants found that probiotic supplements did not reduce the incidence of antibiotic-associated diarrhea. The study also showed no difference in the frequency and severity of diarrhea between those who received probiotics and those who took a placebo.
Researchers are testing a skull-based connector behind the ear for powering heart pumps, aiming to reduce infections at the abdominal site. The study compares two similar devices with internal power cords routed through the neck or behind the ear, seeking better infection prevention and quality of life for patients
Researchers at the University of Maryland Center for Environmental Science have successfully developed a completely vegetarian diet that supports fast-growing marine carnivores like cobia and gilthead sea bream. This breakthrough could significantly ease aquaculture's reliance on wild-caught fish, making the industry more sustainable.
A study found that naltrexone treatment reduced the percentage of days drinking among patients with posttraumatic stress disorder (PTSD) and alcohol dependence. The combination of prolonged exposure therapy and naltrexone did not increase drinking or alcohol craving, contradicting common views.
A new report reveals that 68% of US wind turbines installed between 2003-2012 were for distributed wind projects, generating 812 megawatts of power. This represents a significant shift towards local energy production, with large turbines being used in more distributed wind projects.
Researchers at Arizona State University have developed a new design for salmonella-based vaccines that can survive the acidic environment of the stomach. This improvement allows for stronger immune responses and potentially longer-term protection against diseases.
A new UC Berkeley study reveals that sleep-deprived brains prefer unhealthy snacks and junk foods over whole grains and leafy greens. The researchers found impaired activity in the frontal lobe but increased activity in deeper brain centers that respond to rewards.
A new study found that high levels of physician verbal abuse are closely associated with more negative work environments. Nurses who experienced verbal abuse reported lower job satisfaction, unfavorable perceptions of their work environment, and greater intent to leave their current jobs.
Research finds that messy desks stimulate creative thinking and inspire breaking free from tradition, leading to fresh insights. Tidy desks, on the other hand, promote healthy behaviors like donating to charity and choosing a healthier snack option.
Researchers at MIT created a layer of tiny grains that can funnel acoustic waves, potentially leading to smaller electronic devices and new types of blast-shielding material. The discovery could also enable the development of microbalances capable of measuring tiny changes in weight.
The article highlights the need for a systematic framework of case identification, triage, and mental health interventions in post-disaster settings. Researchers found that standard treatments like pharmacotherapy and psychotherapy are effective, but psychosocial interventions have not been sufficiently evaluated.
The Louisiana Tumor Registry has been awarded a contract to continue its work as a SEER Program-designated cancer registry, collecting cancer incidence and survival data from 28% of the US population. The funding will support cancer research, including prevention, early detection, treatment, and survivorship studies.
A QUT study found that extensive breast cancer surgery is linked to an increased risk of developing arm lymphoedema. The study revealed one in five women may be diagnosed with the condition, which can cause anxiety, depression, and emotional distress.
A new study reveals that certain patient groups feel unmet needs for greater involvement in cancer treatment decisions. Younger patients and those with specific rare types of cancer want more input in the decision-making process. The research emphasizes the importance of shared-decision making policies to address these disparities.
Researchers have identified a novel component, Par-1, of the Hippo signaling pathway, which influences Hippo protein phosphorylation and regulates organ growth. The study found that Par-1 negatively regulates Hippo kinase activity, promoting apoptosis and reducing tissue growth.
Researchers at Ohio State University have restored immune function in spinal injured mice, providing a potential explanation for why people with spinal cord injuries become susceptible to infections. By targeting specific hormones involved in autonomic dysreflexia, the study offers new therapeutic targets for reversing central immune d...
Scientists analyzed 500-year-old Inca mummies to uncover the truth behind the 'capacocha' ritual, revealing that children consumed coca and alcohol before sacrifice. The findings provide new insights into the ancient practice, which was used to sedate children before their death.
Researchers will develop biomimetic materials with self-replicating and evolving properties using DNA-guided self-assembly and origami folding. The goal is to create self-replicating 3D arrays with potential applications in advanced materials, biofuels, and industrial products.
A three-year international study found that marine species are shifting their geographic distribution towards cooler regions due to warming oceans. This has led to changes in breeding patterns, life cycles, and potentially significant repercussions for human services dependent on these ecosystems.
Researchers found that certain stimuli, such as flu infection, fever and stress hormone release, trigger bacteria to leave biofilms in the nose and enter sterile organs, revealing increased virulence. Understanding this mechanism could lead to ways to block the transition to disease.
Research on Malagasy black-and-white ruffed lemurs found that communal nesting and creches significantly improve infant survival rates. Female lemurs can spend less time at their nests, increasing opportunities to feed elsewhere.
The Translational Genomics Research Institute received a $20,000 grant from the Arizona Community Foundation to support its TGen2School program, promoting scientific literacy and preparing a better-prepared bioscience workforce. The initiative includes professional development for teachers and provision of science kits.
A new bed bug trap captures twice as many insects as current traps by incorporating a pitfall trap design, a chemical lure, and a sugar-and-yeast mixture producing carbon dioxide. The trap's taller design makes it harder for bed bugs to escape.
Researchers have created a method to control quantum bits using resonances in artificial atoms, enabling exponential parallel computation and solving complex tasks. The technique combines classical solid-state physics with atomic physics techniques, allowing for controlled electron spin orientation without measurement.