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Science News Archive May 2016 - Page 26


Page 26 of 38

Long-term survival achieved in metastatic melanoma with personalized vaccine

Two patients with liver metastasis from melanoma survived for at least 8.5 and 12 years after receiving patient-specific immunotherapeutic vaccines. The vaccines were derived from the patients' own dendritic cells loaded with proteins isolated from their tumors. Co-Editor-in-Chief Donald J. Buchsbaum, PhD, describes these results as

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalCancer Biotherapy and Radiopharmaceuticals·DateMay 10, 2016

Alcohol accelerates liver damage in people living with hepatitis C

A new study published in the American Journal of Preventive Medicine found that excessive alcohol use can accelerate liver damage in people living with hepatitis C. The research suggests that comprehensive approaches to care are needed for these patients, including increased diagnosis and effective interventions to reduce alcohol use.

SourceElsevier Health Sciences·JournalAmerican Journal of Preventive Medicine·DateMay 10, 2016

How does robotic video-assisted thoracoscopic surgery compare to VATS for treating lung cancer?

A new study published in Journal of Laparoendoscopic & Advanced Surgical Techniques shows that robotic video-assisted lung resection achieves comparable outcomes to conventional VATS and preserves more healthy lung tissue. The robotic approach allows for fewer conversions to open thoracotomy and more lymph nodes retrieved for testing.

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalJournal of Laparoendoscopic & Advanced Surgical Techniques·DateMay 10, 2016

CNIC researchers discover the molecular mechanisms that produce the heart's contractile structure

Researchers at CNIC have discovered a crucial mechanism underlying the contractile structures in both hearts and skeletal muscles. The study reveals how Chd4/NuRD acts as a molecular key to shut down one muscle program in another, leading to hybrid striated muscles that can cause severe myocardiopathies and polymyositis-type myopathies.

Study links parental depression to brain changes and risk-taking in adolescents

A new study found that parental depression is linked to increased brain activity in areas responsible for risk taking in adolescent children, leading to more rule-breaking behaviors. The study suggests that even mild depressive symptoms in parents can influence teens' behavior through changes in the brain's response to rewards.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalSocial Cognitive and Affective Neuroscience·DateMay 10, 2016

The Lancet: Link between weekend hospital staffing and patient deaths represents 'major oversimplification', say two new studies

Two new studies published in The Lancet find no association between weekend senior doctor staffing levels and mortality, instead highlighting variations in quality of care throughout the week. Researchers suggest that policies to address weekend quality of care alone represent a major oversimplification of the problem.

SourceThe Lancet·JournalThe Lancet·DateMay 10, 2016

Why cancer drugs can't take the pressure

Researchers discovered that high-pressure environments in solid tumors, fueled by hyaluronic acid, hinder drug delivery. Treatment with an enzyme that breaks down hyaluronic acid can restore vessel expansion and improve treatment outcomes for drug-resistant cancers.

SourceCell Press·JournalBiophysical Journal·DateMay 10, 2016