Researchers discover over 31,000 repurposable drug candidates for various diseases, including Parkinson's and tuberculosis. The study uses computational methods to identify shared properties between genes, drugs, and diseases, promising a more efficient and cost-effective approach to pharmaceutical discoveries.
Research from NC State University and American University found that capacity grants stimulate long-term financial growth for nonprofits. However, specific financial capacity grants do not provide additional benefits compared to other types of capacity grants.
A recent study by WCS found over 1,000 juvenile hawksbill sea turtles at Glover's Reef, indicating a positive conservation effort. The protected waters provide a safe haven for the species to thrive, with a high survival rate and promising implications for the Caribbean region.
Researchers at Indiana University's Biocomplexity Institute developed a virtual model of the human liver to analyze drug absorption. The study suggests that virtual tissues models could play an important role in modern pharmacokinetics, reducing the risk of overdose from drugs like acetaminophen.
Researchers at UTA will lead a collaborative effort to use UAVs for remote inspection of highways and railroads. The project aims to develop guidelines for safe and efficient use of UAVs, leveraging their advantages in speed, safety, and cost compared to human on-site inspections.
An international team has made a breakthrough by trapping an intermediate in the mechanism of heme peroxidase enzymes and determining its structure using neutron beams. This finding could change our understanding of how these enzymes work, shedding new light on their role in biochemical processes.
Smokers under 50 are significantly more likely to have a major heart attack than older smokers, with the risk dropping with age. The study found that younger smokers face an almost 8-fold higher risk of STEMI than non-smokers, making them particularly vulnerable.
A new website created by Nicole Hassoun and a group of professors and students at Binghamton University uses big data to rank university philosophy departments and academic journals by gender, highlighting the underrepresentation of women in philosophy. The site aims to provide better data for setting targets and evaluating performance...
A University of Arizona researcher is investigating how men perceive their role in preventing the spread of human papillomavirus (HPV). Her study found that most college-age males had heard of HPV but lacked knowledge about a vaccine that could prevent related cancers for both males and females. The researcher emphasizes the importance...
Researchers discovered a genetic link between abdominal aortic aneurysm and four genes, which could help doctors understand the condition better. The study found that early detection is key to preventing fatal internal bleeding, and a new research programme will investigate the effect of these genes on AAA growth.
A study finds that only 6% of plastic surgery tweets come from board-certified plastic surgeons. The researchers call for experts to engage and educate patients and the public about plastic surgery on Twitter.
A new research paper from the University of Luxembourg outlines a method to identify patterns in options traders' behavior influenced by short-term market perceptions. Sophisticated investors use these patterns for profit, but the approach can exacerbate expected price plunges.
A team at HZB and Univ. of Freiburg has cooled 10 million ions to 7.4 K using a novel method, allowing for cryogenic X-ray spectroscopy and studying magnetism and ground states of molecular ions. This achievement paves the way for developing new materials for energy-efficient information technologies.
Researchers at the University of Washington have developed a new nanocarrier system that can deliver chemotherapy drugs and imaging molecules to tumors, sparing healthy tissue from toxic side effects. The hybrid nanocarriers can also provide sustained imaging for months, enabling doctors to visualize tumors more effectively.
A recent study found that BORN TO MOVE participants increased their push-up performance by 111 percent and participated in more moderate-to-intense physical activity compared to regular school PE classes. The program also boosted motivation and enjoyment among participants, leading to improved overall fitness and health outcomes.
A study published in PLOS ONE reveals the potential clinical utility of an integrated, multi-modal battery of oculomotor, vestibular, and reaction time tests for detecting concussions. The results show promising sensitivities and specificities, paving the way for objective diagnostic tools at the point of injury or in emergency rooms.
E-cigarette users may face a similar risk of complications after plastic surgery as traditional cigarette smokers. Refraining from e-cigarette use four weeks before surgery is recommended based on current best knowledge.
Researchers found that amphetamine slows down body temperature rise and masks fatigue in rats, allowing them to run longer. However, this mechanism can lead to dangerous overheating of muscles, posing a significant health risk.
In a phase I clinical trial, combination therapy of CB-839 and everolimus resulted in tumor control in 93% of patients with clear cell and papillary renal cell cancer. The median time without cancer growth was 8.5 months, suggesting potential as a treatment option for advanced kidney cancer.
Researchers at Rice University have developed a new way to dissipate heat in next-generation microelectronic devices by using bumpy surfaces with graphene. The interface between gallium nitride semiconductors and diamond heat sinks was improved, allowing phonons to disperse more efficiently. This improvement can lead to better reliabil...
Jorge Cueto's PhD thesis focused on developing telescoping structural systems for 'rise on demand' flood walls, which can be installed below ground level and raised when flooding occurs. His company, Smart Walls Construction LLC, recently received a $225,000 NSF grant to test and commercialize the invention.
A Yale-NUS professor has discovered an 'alarm response' in medaka fish to a semiochemical released due to physical injuries, providing insights into the brain's processing of danger. This finding will facilitate comparative neural circuit analysis between medaka and zebrafish, shedding light on fear mechanisms.
The US feral horse population is projected to reach 116,300 by 2025, posing a unique challenge for management solutions that consider ethics and perception,
Researchers at Johns Hopkins Medicine found evidence of brain injury and repair in young NFL players compared to a control group. PET imaging revealed higher levels of a biomarker associated with brain injury in eight of the 12 brain regions studied, suggesting a link between concussions and chronic traumatic encephalopathy (CTE).
Research found that swimming, racquet sports, and aerobics are associated with reduced risk of death from any cause and cardiovascular disease. Racket sports showed the strongest association, followed by swimming and aerobics.
A new study shows that toddlers can understand when others have different thoughts from them, indicating they may be able to recognize when adults are lying. This suggests that children's cognitive abilities may be more advanced than previously thought.
Monash University scientists have uncovered evidence of how baleen whales evolved from biting prey with teeth to filtering using baleen. The discovery sheds light on the complex evolutionary change that led to the rise of filter-feeding in these massive creatures.
A recent study identified five genetic variants associated with higher levels of isoleucine, leucine, and valine, which are linked to an increased risk of type 2 diabetes. The researchers also found that these genetic variants were more common in individuals with impaired metabolism of branched-chain amino acids.
A Northwestern University research team developed a mathematical model that predicts the evolution of two distinct subspecies in ornamented animals, one with flashy ornaments for attracting mates and one with subdued ornaments. The study found evidence from nature agrees with the model, showing many species split into these subgroups.
A collaborative effort demonstrates that the physical properties of SrTiO3 can be changed by a simple electrical treatment, creating the effect known as piezoelectricity. This discovery opens a new chapter for research into new materials and unusual properties.
Scientists have discovered a new way to study the atomic structure of materials, revealing the existence of 'polarons' that affect the flow of current. The ultrafast electron diffraction technique captures subtle lattice distortions, showing that electrons and atoms move cooperatively, driving deformations in the material's lattice.
A team of Indian researchers created a model to describe the diffusion of liquids through paper, revealing new theoretical details. The study aims to control liquid spreading for precise creation of products involving paper-based technologies.
A recent study found that approximately one-third of Alzheimer's patients use prescription pain relievers, comparable to those without the disease. However, the type and frequency of analgesics used differed significantly between groups. Paracetamol was most commonly used, while anti-inflammatory medications were less frequent.
Researchers found that individuals lacking the CYP2C19 enzyme have a lower risk of depression and larger hippocampi in adulthood. Increased expression of the enzyme is associated with higher suicidal incidences in depressed patients, suggesting that early life influences may contribute to depression's development.
A new metagenomics methodology can quickly diagnose foodborne bacterial outbreaks by analyzing DNA sequencing data. This approach identified Salmonella pathogen variants and detected co-infections with Staphylococcus aureus, revolutionizing disease surveillance.
A study found that marijuana use prevalence increased by 6% among men earning less than $20,000 annually between 2007 and 2014, compared to only 2% for women in the same income group. This widening gender gap is linked to economic hardship and insecurity during the Great Recession.
A randomized controlled trial found that providing personalized genetic and phenotypic risk estimates for type 2 diabetes did not significantly increase physical activity among healthy adults. Despite improved perception of risk, participants showed no notable behavior changes or weight modifications.
Researchers discovered that ants share proteins and hormones through trophallaxis, allowing them to collectively influence colony growth and development. This process enables ants to cast 'quantitative ballots' for their colony's future by administering different amounts of growth-promoting components to their larvae.
Researchers at the University of Tokyo have discovered a correlation between groundwater helium levels and stress on inner rock layers near the epicenter of earthquakes. The study found that high-stress areas had higher helium-4 levels in groundwater, suggesting a potential risk indicator for earthquakes.
Researchers at Courage Kenny Rehabilitation Institute present studies on improving walking speed in stroke patients and managing cancer-related cognitive dysfunction, also known as chemobrain. Occupational therapy was found to improve everyday functioning and manage issues like mood, stress, and fatigue in cancer survivors.
A new study presents alarming data on chest injuries in pediatric patients after all-terrain vehicle (ATV) accidents. The study found that pulmonary contusion, pneumothorax, and rib fractures were common, with 8 children dying from their injuries.
A new report by ECDC and WHO Europe reveals that approximately 122,000 people in the EU/EEA are infected with HIV but remain undiagnosed. Easy access to testing is crucial for individuals living with HIV to benefit from life-saving treatment.
Researchers have developed an associative learning model that explains how animals create effective behaviors, such as self-control and tool use. The model suggests that genetic regulation of learning influences species-specific behavior and intelligence.
A landmark clinical trial conducted by researchers at the University of Alberta found that beta blockers and ACE inhibitors effectively prevent a drop in heart function from cancer treatment. The study showed improved safety for breast cancer patients undergoing chemotherapy, with potential benefits to survival rates.
A new study using mathematical modeling found that societies divided into multiple groups are more likely to conserve natural resources and survive than those without sub-group divisions. This is because each group can learn from the successes and failures of others, leading to better institutions for managing resources.
Scientists at NC State University have discovered a way to make pinpoint changes to an enzyme-driven assembly line that will enable the creation of new antibiotics with desired properties. By tweaking the function of individual modules in the enzyme, researchers can design man-made molecules with precise control.
Researchers at the University of Delaware developed models to improve environmental conservation on military bases, resulting in a 21% increase in military readiness and environmental protection. The study found that by considering the cost-effectiveness of project selections, the DoD can achieve significant benefits with reduced costs.
The new observatory will record high-resolution images of the Sun every five seconds, measuring internal gravity waves and their role in transporting energy and momentum. The data will aid in understanding space weather events, solar coronal heating, and the structure of the Sun's atmosphere.
Researchers analyzed incubation rhythms of 32 monogamous shorebird species across 729 nests, finding significant within- and between-species diversity. The study suggests that the risk of egg loss from predators is a key factor determining incubation bout lengths, with cryptic nest behavior influencing this relationship.
A study found that child care personnel properly clean their hands less than a quarter of the times they are supposed to. Handwashing is essential in early childhood centers, especially among young children with partially developed immune systems.
A new study using national patient ratings website data found that most US radiologists receive favorable satisfaction scores from their patients. The study also showed that radiologists in the Northeast scored lower than those elsewhere, and online reviews tend to be strongly positive or negative.
A WSU research team has successfully used a mild electric current to kill drug-resistant bacterial infections, including Pseudomonas aeruginosa PAO1, responsible for chronic and serious infections in lung diseases and wounds. The technology uses an antibiotic in combination with the electric current to disrupt biofilm matrices, damage ...
Researchers at the University of Chicago created a new tool to view the spectrum from specific structures within samples. The instrument, a spatially selective microscope, allows users to zero in on the spectrum from specific regions of interest and capture standard fluorescence images of the whole field of view.
Researchers found that CRPS patients' brains activate similarly to normal pain when observing movements, suggesting a connection between pain processing and motor control. The study may help develop diagnostics and therapeutic strategies for CRPS patients.
A study by Eriko Aiba found that professional musicians' brains process musical information differently, depending on their prioritization strategy. Some prioritize sight and others rely on auditory memory to learn music, leading to the development of efficient learning methods tailored to individual brain strategies.
Scientists employed kinesin motor proteins to detect stretching and compressing of soft silicon-based material polydimethylsiloxane (PDMS). The study found that microtubules moved faster and aligned themselves in response to stretching, while slowing down and aligning perpendicular to compression.
A new clinical trial found that consuming milk with only A2 protein increased the concentration of glutathione, a critical antioxidant, in healthy adults. This may help strengthen the body's disease-fighting power and reduce the risk of degenerative diseases.
Researchers at North Carolina State University have developed a novel fabrication technique for more efficient plastic solar cells. The new method uses sequentially cast ternary systems to prevent alloying issues, resulting in wider optical sensitivity and increased efficiency.
Elena Long's research aims to study the structure of nuclei by exploring how six quarks give rise to a binding force. She plans to use a new target made of deuterated ammonia to apply strong magnetic fields and measure polarization, gaining insight into matter's underlying structure.
Researchers found that myocarditis is affecting both children and adults worldwide, with men being twice as likely as women to develop severe reactions. Early diagnosis is key to preventing long-term heart damage, and new investigational therapies are soon to be tested.