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Science News Archive July 2017 - Page 6


Page 6 of 37

Compound shows promise in treating melanoma

Researchers at Penn State have developed a compound that inhibits tumor growth by 69% in a mouse model and killed human melanoma cells. The compound targets the Akt1 pathway and human topoisomerase IIα activity, contributing to melanoma tumor growth.

SourcePenn State·JournalEuropean Journal of Medicinal Chemistry·DateJul 26, 2017

Cave mazes

Analysis of caves in Israel reveals they formed through dissolution by rising groundwater, originating from highlands and deep faults. The findings have implications for understanding far-field groundwater systems and the possible circulation of fluids, dating back to the Oligocene-early Miocene periods.

SourceGeological Society of America·JournalGeological Society of America Bulletin·DateJul 26, 2017

How plant architectures mimic subway networks

Researchers found that plant architectures mimic subway networks by balancing competing objectives of cost and performance. By analyzing 3D scans of growing plants, the team identified a universal design principle guiding plant growth, which could help increase crop yields or breed plants better adapted to climate change.

SourceSalk Institute·JournalCell Systems·DateJul 26, 2017

Trees can make or break city weather

A new study found that trees can increase wind speed by a factor of two when removed, making it more challenging for pedestrians to walk. Trees also reduced the impact of wind pressure on buildings, particularly through small gaps, and contributed to a more comfortable environment.

SourceUniversity of British Columbia·JournalAdvances in Water Resources·DateJul 26, 2017

Should doctors work longer shifts?

Experts argue that working 24-hour shifts may not negatively impact patient care, but can lead to burnout. The medical profession must address the issue of sleep deprivation and its effects on doctors' wellbeing and patient safety.

SourceBMJ Group·JournalThe BMJ·DateJul 26, 2017

Novel thermal ablation system for transdermal drug delivery

Researchers at Kumamoto University developed a photothermal ablation system to enhance transdermal delivery of protein-based drugs. The system, using gold nanorods and near-infrared light, increased skin permeability and successfully delivered proteins in both in vitro and in vivo experiments.

SourceKumamoto University·JournalEuropean Journal of Pharmaceutics and Biopharmaceutics·DateJul 26, 2017