A study by the University of Liverpool found that polypharmacy and multimorbidity are linked to an increasing burden of adverse drug reactions, with 16.5% of hospital admissions caused by medicine-related harm. The researchers call for a whole-systems approach to address overprescribing and improve patient care.
Researchers from Politecnico di Milano have developed a programmable photonic processor that can separate and distinguish optical beams even if they are superimposed. This device allows for high-capacity wireless communication, with transmission rates of over 5000 GHz.
Researchers found that WASH interventions supplying filtered water, improved sources, or basic sanitation services significantly reduced diarrheal risk. The study highlights the importance of improving WASH infrastructure and programming to prevent disease, particularly among young children.
Research from Washington University in St. Louis finds that positive social interactions are associated with a greater sense of purpose in older adults, particularly those who are retired. The study suggests that the quality of relationships and social connections play a significant role in shaping one's sense of purpose.
A University of Alberta study reveals that stressful childhood environments can lead to a desire for high-energy-dense foods throughout life, contributing to higher obesity rates. Adults raised in harsh socioeconomic conditions were more food-motivated and preferred energy-dense foods.
A new giant dinosaur species has been discovered in Patagonia, providing insight into the evolution and biology of dinosaurs like Tyrannosaurus rex. The research reveals that large carnivorous dinosaurs grew their skulls larger while their arms shortened over time.
A recent analysis found that Big Tech companies can provide innovative financial services to people excluded from traditional banking, improving financial inclusion. However, the authors caution that without proper education, these services may introduce risks to financial stability.
Researchers found serious security issues in 42 daycare apps, allowing access to private photos and personal data without consent. The analysis highlights inadequate privacy policies and recommendations for guidelines and checklists to ensure compliance with data protection regulations.
A systematic review and meta-analysis of 39 publications found a global association between COVID-19 measures and reduced breast, colorectal, and cervical cancer screenings. This could lead to an increase in avoidable cancer deaths.
Scientists developed a novel multilayer coating to improve the longevity of steel, increasing its lifespan by up to 400 hours. The coating, comprising three layers, was found to provide higher resistance to rust than conventional Zn coatings.
Photoinduced large polaron transport and dynamics in organic-inorganic hybrid lead halide perovskite have been studied using terahertz probes. The researchers found that the formation of large polarons protects charge carriers from scattering with grain boundaries or defects, explaining the long lifetime of photoconductivity.
Researchers at the University of Wisconsin-Madison have discovered a direct link between the p53 and PI3K/Akt pathways in cancer cells. The study identified two enzymes, IPMK and PIPKIa, as key regulators of these pathways, offering new insights into potential cancer treatments.
Childhood obesity rates are increasing, with younger children affected and severe cases reported. The study found that despite public health efforts, the incidence of obesity in elementary school children has risen higher and earlier than previously thought.
Freeform optics have revolutionized the way we approach precision optical systems, enabling superior imaging in compact packages. Researchers have summarized the present state of art in advances, design methods, manufacturing, metrology, and applications. Key challenges include standard definitions, optimization complexities, and measu...
A recent study found regional variations in iodine status across Canada, with higher deficiency rates in Vancouver and Quebec City. The researchers identified dietary sources of iodine, including seaweed, seafood, and dairy products, as well as environmental factors that may contribute to lower iodine intake.
Researchers have uncovered thousands of artifacts along Mexico's Yucatán Peninsula, shedding new light on the ancient Maya people who lived in a dynamic interplay between social and natural processes. The project has provided valuable insights into how the Maya adapted to environmental changes, such as rising sea levels, and offers a m...
A case study from India shows that police reforms improve responsiveness to gender-based violence, especially when female officers staff dedicated women's help desks. However, the reforms have mixed results, with women still under-reporting crimes and arrest rates largely unaffected.
Researchers at Insilico Medicine used their proprietary AI-driven target discovery engine, PandaOmics, to identify 17 high-confidence and 11 novel therapeutic targets for ALS. These targets were further validated in various model systems, including a c9ALS Drosophila model, and showed strong functional correlations to ALS. The study's ...
A novel DNA-delivered antibody approach has advanced to clinical trials to prevent COVID-19. The approach utilizes the body's own cells to produce targeted protective antibodies, simplifying the development and production process for biologics.
Scientists have discovered evidence that yunnanozoans are the oldest known stem vertebrates, with cellular cartilages in the pharynx similar to those found in modern vertebrates. The team's findings support the evolutionary placement of yunnanozoans at the very basal part of the vertebrate tree of life.
Researchers challenge the notion that natural selection declines after reproduction is complete. Instead, they propose that older adults play a crucial role in maintaining their fitness through intergenerational transfers of resources and knowledge.
Researchers at Scripps Research and UC San Diego have developed a tool to detect SARS-CoV-2 variants in wastewater, enabling public health officials to track pathogen variants more accurately. The 'Freyja' algorithm can identify new variants of concern up to 14 days before traditional clinical testing.
The 13th Five-Year Plan set goals for green building technologies to improve planning and design, energy efficiency, indoor air quality, high-performance structures and materials, and green construction systems. Despite progress, the number of certified buildings remains low, highlighting challenges in implementing these technologies.
Scientists have found that prior exposure to Staphylococcus aureus prevents effective vaccination due to immune response memory. To overcome this, the research suggests targeting only the protective component of the protein IsdB, generating a more effective vaccine against MRSA.
A study of nearly 9,400 COVID-19 patients found that remote monitoring significantly improves symptom management and reduces the need for hospitalization. The findings suggest that remote monitoring can help hospitals better manage bed capacity during the pandemic.
A new distributed recycling system using microwave irradiation recovers 97% of manganese oxide and zinc from spent alkaline batteries, outperforming conventional methods. The system's potential to reduce annual energy consumption and greenhouse gas emissions in Japan is estimated at 26,500 GJ and 1.54 Gg-CO2 eq, respectively.
A new study by the University of Pittsburgh found that patients with diabetes on Medicare Advantage plans are more likely to receive preventive treatments, but less likely to receive newer and more expensive medications. This disparity can lead to poorer health outcomes, including higher blood pressure and worse diabetes control.
Columbia researchers built a 2.6nm-long single molecule wire that exhibits an unusual increase in conductance as the wire length increases and has quasi-metallic properties. The breakthrough overcomes the exponential-decay rule, enabling electronic devices to become even tinier.
A team of researchers has successfully created complex artificial tissue models, including a full-scale human heart model, using focused rotary jet spinning. This method enables the creation of intricate details and spatially varying alignment, rivaling biological tissues in mechanical behavior.
A study from the University of California, Davis, found that balancing protein consumption with human needs can reduce nitrogen excretion rates in US waters by 27% by 2055. Coastal cities have the largest potential to make this change, which could also improve environmental health without increasing wastewater treatment costs.
A study predicts UK wine production will increase due to climate change, with areas in England and Wales becoming suitable for sparkling wine grape varieties. The research highlights the potential for high-quality still wine production, particularly for Pinot Noir and other disease-resistant varieties.
Researchers highlight the importance of linking carbon conservation with threatened forest primates, which could enhance climate action and biodiversity protection. The study found that 15.5 gigatonnes of irrecoverable carbon are stored in areas with high primate species richness, equivalent to 40% of current annual fossil fuel emissions.
A new computer model developed by Louisiana State University oceanographer Giulio Mariotti shows that barrier island retreat will accelerate by 50 percent within a century due to rising sea levels. The model challenges the common assumption that barrier islands respond instantly to sea level rise, revealing a lag between the two.
A new machine learning model accurately predicts the behavior of millions of human gut microbial communities from hundreds of experiments. The model enables designing communities with desired metabolite profiles, which may help doctors discover ways to treat or protect against diseases.
Researchers found a correlation between Arctic ozone depletion and extreme weather events in the Northern Hemisphere. Simulations suggest that reduced ozone levels contribute to warmer temperatures and droughts in central Europe, while wet conditions prevail in polar regions.
Researchers have developed an experimental platform to demonstrate the quantum fault-tolerant threshold, a crucial concept in quantum computing. The team observed the error rate threshold using two entangled photons and confirmed its existence through single-qubit and two-qubit operations.
The OSIRIS-REx mission has collected a sample from asteroid Bennu, which will be analyzed in 2023. The study found that the asteroid's surface consists of low-cohesion rubble and sub-surface material is darker and more fine-particle-rich than the overlying surface.
The North American Menopause Society has released its 2022 Hormone Therapy Position Statement, reaffirming the effectiveness of hormone therapy in treating hot flashes and other menopause symptoms. The updated statement also highlights its role in preventing bone loss and fractures.
A new study takes inspiration from the 'waggle dance' of honeybees to devise a way for robots to communicate effectively in situations with unreliable network communications. Researchers designed a visual communication system using on-board cameras, allowing robots to interpret gestures and convey complex information.
A study of 231 Vietnam Era veterans reveals that 71% describe at least one traumatic event, including combat exposure, adverse childhood experiences, and navigating a life-threatening illness. The findings underscore the importance of clinician-patient relationships and trauma-informed care in older adult healthcare.
A team of researchers from Tokyo University of Science has developed an efficient integrated materials synthesis system for automatic discovery of new functional magnetic materials. Using artificial intelligence and computational science, they identified promising materials five times more efficiently than traditional trial-and-error a...
Research suggests that paternal genetic factors play a role in susceptibility to preeclampsia, but the impact of paternal phenotype and lifestyle remains unclear. The study found no significant differences in socioeconomic background or health history between fathers with preeclamptic pregnancies and those without.
A study by University of Otago's Department of Tourism found that the reduced number of event-related personnel attending the Olympics due to Covid-19 resulted in lower CO2 emissions. The study estimates a reduction of 129,686 tCO2 from expected levels.
A long-term study of 3,926 adults with CKD found that higher levels of physical activity reduced the risk of atherosclerotic events, new-onset heart failure, and death. The association was strongest for incident peripheral arterial disease and reinforces current guideline recommendations.
A large-scale study by Rutgers researcher Alan Robock and colleagues found that even small nuclear wars would rewire the physical, biological, and ecological states of oceans. The study simulated a U.S.-Russia war and several smaller India-Pakistan wars, calculating the effects of atmospheric soot on ocean functions.
Researchers review current progress on DUV NLO crystals, discussing key performance criteria, material development, and design strategies to surpass existing KBBF crystals. They propose rational tuning of interlayer cations as an effective strategy to improve DUV NLO performance.
A new study published in Behavior Genetics found that natural selection favors characteristics associated with lower earnings and poorer education, such as having more children. The research, led by UEA, analyzed data from over 300,000 people in the UK and suggests that this may be contributing to increasing income inequality.
Researchers at UT Austin create biosensors that can detect therapeutic compounds in bacteria, enabling faster and more accurate analysis. This technology has the potential to revolutionize drug production by providing a sustainable alternative to current processes.
Researchers at Eindhoven University of Technology accidentally discovered that adding more water to a liquid solution turns it back into a gel, and then further dilution forms another gel. The team's findings have significant implications for various fields in chemistry and biology.
A novel point-of-care biosensing device has been developed to detect measles virions in human saliva, potentially aiding in viral spread control. The device, smaller than a €1-cent coin or U.S. quarter, utilizes lab-on-a-chip technology and showed high accuracy in experiments.
Physicists have successfully entangled two atomic quantum memories over a 33-kilometer-long fiber optic connection, setting a new record. The entanglement is mediated via photons emitted by the two quantum memories and has potential applications in large-scale quantum networks and secure communication protocols.
The Three Gorges region experienced frequent climate extremes in 2021, including abundant rainfall and record-breaking extreme weather events. The study highlights the importance of monitoring climate anomalies and improving observations to better understand their impact on the region.
Research published in Clinical and Experimental Allergy reveals a significant increase in prescriptions of specialized infant formula for infants with milk allergies. The findings suggest high levels of milk allergy over-diagnosis, marking an important shift in early child nutrition.
Researchers investigated radiation exposure among health professionals performing structural heart interventions, revealing higher doses for echocardiographers and cardiologists compared to sonographers. The study highlights the need for safer procedures and protective measures to mitigate radiation risks.
Researchers discovered that low-signal-to-ambient noise ratio sounds cause analgesia by inhibiting inputs from the auditory cortex to specific somatosensory thalamus regions. This finding provides a model for investigating the mechanistic underpinnings of sound-induced pain relief.
A study of 720 patients with thoracic cancer found increased odds of unsuccessful telemedicine visits among Black and disadvantaged patients. Unsuccessful telemedicine visits were associated with worse clinical outcomes, highlighting the need for improved access to healthcare.
A study published in the Journal of Applied Research on Children found that both gun-owning and non-gun-owning parents are receptive to discussions about gun locks and firearm safety measures with their child's pediatrician. The study, led by researchers at the University of Pennsylvania School of Medicine, shows promise for reducing f...
Researchers at the University of Illinois Urbana-Champaign have developed a low-cost ultrasound imaging method to study the relationship between Alzheimer's disease and the brain's vascular system. The technique, which provides high-resolution images of animal microvasculature, may aid in early detection of the disease.
Asteroid Bennu's surface is characterized as loosely bound, with a near-subsurface layer composed of weakly bound rock fragments containing twice the void space as the overall asteroid. The study provides new insights into the physical properties of rubble-pile asteroids, with implications for their long-term evolution.
Researchers determined the molecular structure of the HIV Pol polyprotein, a critical component in the virus's replication process. The discovery sheds new light on how HIV reproduces itself and reveals a new vulnerability that could be targeted with drugs.