Sturt Manning's statistical analysis has narrowed the time range for the Thera volcano eruption to between 1609–1560 BCE with a 95.4% probability. This new timeline synchronizes Eastern Mediterranean civilizations and rules out ancillary theories, potentially rewriting history.
A new study found that integrating genetic testing into electronic health records (EHRs) significantly reduces clinician workload, with average savings of 45 minutes per day. Clinicians can now order and manage tests directly through the EHR, resulting in reduced time spent on clerical work.
Food security experts propose 32 threats and 50 research questions to bolster food security in extreme events. Better maps, farm-level interventions and system transformation are identified as key areas for improvement.
A study found that most people with long COVID (persistent symptoms) recover within 12 months. However, some patients still experience symptoms and may benefit from seeing a rheumatologist for autoimmune disorder assessment.
Scientists observed optical gradient force on chiral gold nanoparticles, revealing difference in force between D-form and L-form particles. The study also uncovered a previously unknown effect of wavelength on chirality-dependent optical forces.
Researchers at the University of Rochester Medical Center used fMRI to study how the brain processes complex audiovisual speech. The study found that watching a narrator tell a story activates an extensive network of brain regions involved in sensory processing and cognitive functions associated with comprehension. This finding has pot...
Researchers engineered mosquitoes to produce compounds that stunt malaria parasite growth, reducing the risk of disease transmission. The technique could be combined with gene drive technology to drastically cut malaria transmission in real-world settings.
African American men are twice as likely to have more aggressive disease compared to non-African American men. Genomic biomarker tests like the Decipher score can identify patients with higher-risk disease, enabling tailored treatment approaches.
Researchers at Washington State University identified eight proteins that regulate insulin sensitivity and resistance in hibernating bears, similar to human genes. The discovery could lead to the development of treatments for human diabetes.
A study of 389 Fortune 500 organizations found that female leaders prioritize customer relationships, driving long-term financial performance. Female executives are especially valuable in stable environments with a high degree of control over customer strategy.
Researchers found that waist-to-hip ratio is a stronger predictor of early death than body mass index (BMI), which doesn't take into account fat distribution. A lower waist-to-hip ratio is associated with lower mortality risk, regardless of population studied, and may be a better measure of healthy weight.
Rare-earth metal alloys create new types of color-changing and branching sparks. The study found that these alloys, such as ytterbium and neodymium, produce more colorful sparks than single-metal powders.
Researchers deciphered the diversity and evolution of nerve and gland cell types in sea anemones, revealing common progenitor populations and conserved regulatory mechanisms. The study highlights a remarkable ability of sea anemones to maintain neural balance throughout their lives.
A new study led by researchers at UC Berkeley found instances where arsenic levels exceeded regulatory limits for months or years at a time in the Kern Valley State Prison and nearby communities. Long-term exposure to arsenic has been linked to various health concerns, including cancers.
A global consortium has launched best practice surveillance protocols for Group A Streptococcus (Strep A) research, providing clear case definitions and guiding researchers in clinical trials. The new protocols aim to accelerate the development of a safe and effective Strep A vaccine.
A new study found that financial incentives enhance prosocial decisions in people with low empathy levels. However, this effect does not change the underlying motivation, which remains egoistic. In high empathic individuals, financial incentives have no impact on decision-making.
A new study reveals key differences in dopamine disposal machinery between male and female mice with a rare human genetic variant found in boys with ADHD or ASD. Females exhibit unique behavioral changes, such as increased anxiety and novelty recognition issues, while males display reduced social behavior and perseverative traits.
The University of Tennessee Institute of Agriculture has received a $30 million grant to empower grassland farmers in climate-smart agriculture. The project aims to enhance operation resilience and optimize profitability while improving soil health and biodiversity.
A study by the University of Exeter and Greenpeace Research Laboratories reveals that synthetic nitrogen fertilisers contribute significantly to greenhouse gas emissions. The researchers estimate that the supply chain for these fertilisers is responsible for emitting the equivalent of 1.13 gigatonnes of CO₂ in 2018.
A new study from the University of Maryland cautions that delayed interventions make it harder to eliminate monkeypox. The research suggests that stronger and better-adapted variants may evolve if case numbers are low, making it challenging to control outbreaks.
A 28-year study tracking over 500,000 adolescents in the US found a decline in substance abuse, except for an increase in cannabis and vaping use. Low social engagement and participation in structured activities were key predictors of substance abuse avoidance.
The analysis found that inadequate margin widths may result in higher risks of distant recurrence and breast cancer mortality, as well as increased local recurrence. The researchers recommend a minimum tumour free distance of 1mm from the margin for optimal oncological outcomes.
A study by UC Davis researchers found that socially polarized COVID-19 information on social media fuels anxiety, anger and sadness, leading to incivility. The team analyzed over 375,000 tweets and identified patterns that predict profanity, insults and severe toxicity.
Researchers have developed a novel global-to-local design approach to compose heterogeneous swarms of robots, enabling them to achieve collective behavior. The system allows users to define target behaviors by changing the number and position of distribution's modes, enabling swarms to adapt autonomously.
A UK study found that adults struggling with debt management had higher rates of anxiety, depression, and mental health treatment. The research highlights the importance of addressing debt as a threat to mental health, regardless of income level.
A new method allows researchers to study the contents of lysosomes in mice, enabling them to identify molecules involved in diseases such as Batten disease. By using genetically engineered mice with a molecular tag, scientists can selectively collect and analyze lysosomes, providing valuable insights into the causes of these diseases.
A new study estimates that up to 17.5 million people worldwide will live with Type 1 Diabetes by 2040, with the highest burden in low- and middle-income countries. The modeling study predicts a significant increase in global deaths due to T1D, highlighting the need for improved surveillance, diagnosis, and care.
The T1D Index, a data simulation tool, measures the human and public health impact of type 1 diabetes globally. Simulations suggest over 3.86 million 'missing people' and 32 healthy years lost due to T1D, highlighting the need for interventions such as timely diagnosis, accessible care, and research funding.
Research suggests that stress can affect a woman's probability of becoming pregnant within a menstrual cycle. Women with higher levels of chronic stress had lower fecundability rates compared to those with lower levels. The study found that women with an allostatic load score of 5-6 had a 59% reduction in fecundability.
A new study reveals that just five US universities have trained 1-in-8 tenure-track faculty members, highlighting the dominance of academic pedigree in academia. The research also shows that academics from less prestigious schools are more likely to leave the field and face limited job opportunities at elite institutions.
A recent genetic study has found that three-quarters of the Early Medieval population in Eastern England was comprised of migrants originating from Continental regions bordering the North Sea. These migrants intermarried with local populations, but integration varied greatly from region to region.
This study uses surface-tracked scanning ion conductance microscopy to investigate kinetics of ion transport in ionic redox transistors. It shows that applying a reduction potential facilitates ion ingress into redox sites, driving transmembrane transport.
Researchers discovered a genetic connection between individuals with a predisposition to smoking and poorer outcomes after an ischemic stroke. A meta-analysis of 12 studies found that people genetically predisposed to smoke had a 48% greater risk of poor recovery, supporting the theory that smoking causes worse stroke recovery.
A study by Aston University confirms that taking a break every 20 minutes to look away from screens for at least 20 seconds reduces digital eye strain symptoms. The research, involving 29 participants, showed a marked decrease in symptoms such as dryness, sensitivity, and discomfort after using the reminders.
Neflamapimod, a p38α kinase inhibitor, demonstrates reversible neurodegeneration in animal models and improves clinical endpoints associated with cholinergic neuronal function in patients with dementia with Lewy bodies. The findings support the initiation of a confirmatory Phase 2b clinical trial for neflamapimod.
A new study by an international team of scientists has discovered a complex, dynamically evolving, magnetized environment around a fast radio burst source. The findings challenge current understanding and suggest that the source may be located in a region without significant star-forming activity, defying expectations.
Engineers at Duke University developed a scalable soft surface that can continuously reshape itself to mimic objects in nature. It uses electromagnetic actuation, mechanical modeling, and machine learning to form new configurations and adapt to hindrances.
A phase 3 clinical trial showed tofersen reduces SOD1 and neurofilament light protein levels, slowing down disease progression. Longer-term use may help stabilize muscle strength and control in people with genetic ALS.
Researchers developed the first model of Mars' early atmosphere, linking high temperatures to ocean formation and showing water vapor condensed in the lower atmosphere, while molecular hydrogen escaped. This model supports findings from spacecraft data, indicating Mars was wet and had warm-to-hot oceans for millions of years.
Researchers at MIT Sloan School of Management studied 93 countries and found more than half willing to tolerate higher death rates without NPIs. The US, however, may face high daily death rates exceeding 1,000 per day during winter months if past responsiveness continues.
The devices, made from a combination of stretchy material and dinoflagellate-infused culture solution, trigger light emission through mechanical stress. They can be recharged with sunlight and are maintenance-free, making them suitable for soft robots exploring dark environments.
Researchers have identified two NLRP sensors, NLRP1 and CARD8, as key players in Coxsackievirus B3-induced heart inflammation. Targeting CARD8 may prevent CVB3 infections from progressing to heart failure. The study provides new insights into the inflammatory response triggered by this common viral cause of viral myocarditis.
The global solar industry faces a supply chain risk due to China's dominance in polysilicon production, which can lead to increased carbon intensity and human rights concerns. The US and Indian governments have pledged billions to boost domestic production and create a more resilient supply chain.
Researchers have developed a flexible endoscopic imaging probe using a bendable graded index (GRIN) lens, enabling 3D microscopic imaging of tissue. The new technology could shorten biopsy waiting times to minutes and enable real-time monitoring of tissue changes.
A new study found that mice with the APOE4 gene variant were more likely to die from COVID-19, while those with APOE2 had increased virus replication and inflammation. The researchers also analyzed 13,000 patients in the UK Biobank and found that individuals with two copies of APOE4 or APOE2 were at higher risk of death from COVID-19.
A 28-year study tracked over 500,000 US adolescents and found that low social engagement and participation in structured activities are key predictors of substance abuse avoidance. Conversely, highly social and engaged groups with less supervision were more likely to engage in substance abuse.
A randomized controlled trial found that virtual reality immersion reduced the need for sedatives during hand surgery, leading to lower doses of propofol and shorter post-operative lengths of stay. Patient satisfaction remained unchanged, but discharge times were significantly shorter.
A recent Oregon State University study found that spent hemp biomass is a safe and nutritious alternative feed for lambs, with nutritional quality comparable to alfalfa. The findings provide evidence for the use of hemp byproducts as an animal feedstuff, potentially offering economic benefits for hemp farmers and livestock producers.
A prospective study found that patient decision aids improve patients' self-perceived understanding of image-guided procedures and satisfaction with the consent conversation. Patients who received a PDA before their visit reported significantly greater understanding and felt more listened to by their clinician.
Researchers using FAST telescope discover complex, magnetized environment around FRB 20201124A, contradicting young magnetar engine theories. The team analyzed 1863 bursts of the source, revealing irregular variations and circular polarization.
A nationwide study in France found that hot temperatures were closely linked with weight loss in heart failure patients, indicating a worsening of their condition. This association was strong and clinically relevant, prompting recommendations for healthcare professionals to reduce diuretic medication when weight loss occurs.
A new international study found that maternal education levels and household income at birth are significant predictors of childhood overweight and obesity. Social inequalities were evident across seven high-income countries, with lower maternal education associated with higher risk of overweight and obesity.
Two new studies published in NEJM Catalyst demonstrate the remarkable effectiveness of telemedicine in addressing access barriers and improving health outcomes. The research highlights the benefits of telemedicine for patients with transportation challenges, mental health services, and overall quality of care.
A cohort study of Chinese older adults found that sleeping for more than 8 hours increases dementia risk by 69% and going to bed before 9 PM doubles the risk. The study suggests monitoring cognitive function in those with prolonged sleep timing.
Researchers have genetically engineered human muscle cells to take up more sugar from the blood, reducing blood glucose levels by 20% in diabetic mice. The new tissue also shows promise for a single injection of tissue providing long-lasting glucose control.
A clinical trial found that using positive words and images during the window of heightened brain plasticity after a single ketamine treatment can help maintain depression relief for at least one month. Researchers developed an automated intervention to pair ketamine with computer-based training, showing promising initial findings.
A recent study by Texas Tech University Health Sciences Center researchers has shed light on the mechanisms of salt transport across membrane barriers. The findings have significant implications for treating cystic fibrosis, a disease caused by mutations in three types of sodium-potassium pumps.
Researchers developed a stable seawater oxidation electrolysis platform using a nickel-iron layered double hydride array with benzoate ions, achieving efficient and stable hydrogen production. The platform overcomes the corrosion issues caused by chlorine in seawater, enabling uninterrupted electrolysis for 100 hours.
Researchers found that getting enough sleep influences the environment where monocytes form, develop, and get primed to support immune function. This process, hematopoiesis, occurs in the bone marrow and can accelerate clonal hematopoiesis, an age-related condition linked to cardiovascular disease.
Researchers have discovered a way for plants to adapt to drought by modifying their lignin chemistry, enabling them to grow and thrive in challenging conditions. By understanding the 'chemical code' of lignin, scientists can develop crops and trees that are more resilient to climate change stresses.