A recent study has identified a gene, Zelda, that plays a crucial role in regulating the end of regrowth in fruit fly larvae. The researchers found that Zelda helps control the activity of genes involved in tissue development, revealing a new understanding of the regenerative process.
A study found that a grandmaternal age difference of ≤-9 years significantly increases the risk of pregnancy cardiometabolic disorders. The researchers analyzed data from 2,235 grandmother-mother pairs and discovered a nonlinear association between age differences and CMDs.
Researchers introduce a novel design approach for 3D rotary braiding machines, enabling the production of intricate shapes and complex geometries. The new methodology achieves this by varying the number of incisions and combining different cut-circles, resulting in increased carrier capacity and improved mechanical properties.
Researchers at UCLA have discovered a chromatin-based strategy that enables cells to rapidly produce proteins when nutrients are scarce. This 'priming' mechanism, driven by the MYC gene, allows cancer cells to adapt and survive under metabolic stress.
Researchers developed a new protocol to detect even low levels of T. cruzi parasites in patients, allowing for accurate monitoring of treatment outcomes and potentially leading to more effective drug treatments. The test was tested on human, macaque, and canine subjects, with promising results.
A new preclinical study from Weill Cornell Medicine found that a combination of small molecules extended the survival of transplanted pancreatic islets in female mice, while adding two molecules to the mixture boosted cell survival in male mice. This breakthrough could allow physicians to treat more patients with fewer cells.
Researchers have developed perovskite solar cells that can effectively convert indoor lighting into electrical power. The cells achieved a power conversion efficiency rate of 38.7% under dim light conditions, making them suitable for charging devices in various environments, including offices.
Global survey of 4,351 participants reveals that people in more equal and wealthy societies are more likely to condemn excessive wealth. Moral condemnation is linked to values related to equality, purity, and younger age, suggesting concerns about the corrupting influence of wealth.
Researchers propose a comprehensive solution integrating waste management and carbon sequestration in the coal industry. The study investigates mineralizing low-concentration CO2 using single coal-based solid wastes, significantly enhancing CO2 sequestration capacities.
The American College of Cardiology hosts a Health Equity Summit to address cardiovascular health disparities. Young Indigenous scholars from the NNAYI participate in interactive cardiology workshops to promote equitable healthcare.
This study examines breast cancer incidence trends in older US women by racial and ethnic groups, geographic location, and cancer stage. The analysis reveals differing patterns across age groups, highlighting the importance of considering screening guidelines when analyzing breast cancer incidence rates.
A new type of laser developed by Norwegian University of Science and Technology and partners has solved several problems associated with current-day lasers. The laser can be used in self-driving cars and detects hydrogen cyanide gas in the air with high precision.
A highly aligned and compact MXene film exhibits exceptional electromagnetic interference (EMI) shielding effectiveness across ultra-broadband frequencies. The innovative film, developed by Professor Xuchun Gui's team, demonstrates infrared stealth capabilities making it a promising candidate for advanced stealth applications.
The essay competition aims to expand on Schrödinger's fascination with the connections between quantum theory and biological processes. Entrants will explore questions such as whether life evolved the ability to make use of the counterintuitive properties of the microscopic world, and how this might relate to consciousness.
The WSIS+20 High-Level Event 2025 in Geneva will assess 20 years of using digital technologies for progress and chart the future direction ahead of the UN General Assembly review. The event will tackle critical issues like the digital divide, AI governance, and sustainability.
Naval Research Laboratory internships provide students with cutting-edge research experiences and opportunities for career growth. With real-world applications in national defense and future careers, these programs offer students the chance to advance their innovation.
A dual-protective approach using Botox and an anti-nausea patch significantly reduces salivary gland toxicity in prostate cancer patients undergoing PSMA-targeted radiopharmaceutical therapy. This strategy led to a 30% decrease in PSMA uptake by the salivary glands without affecting the treatment's cancer-fighting efficacy.
A Mount Sinai study found a post-pandemic increase in head and shoulder injuries among female and male youth hockey players, with higher rates of hospitalizations and fractures. The research highlights the importance of safer equipment standards, injury prevention strategies, and education to protect young athletes.
A study by Cornell University research finds that conspiracy believers are dispositionally overconfident and massively overestimate how much others agree with them. They genuinely think themselves to be in the majority, even if they're in a tiny minority, despite being unaware of their fringe beliefs.
Researchers at Osaka Metropolitan University have identified the REDD2 gene, which is activated by metabolic stress and damages pancreatic β-cells, leading to reduced insulin secretion and the onset of diabetes. Suppressing REDD2 expression protects β-cells from damage, even under stress from overeating, preventing the onset of diabetes.
The Western Pacific Subtropical High's (WPSH) predictability has significantly improved over the past century, mainly due to robust oceanic signals from the Indo-Pacific region. Three persistent oceanic predictors have emerged as crucial sources of predictable signals, accounting for 59% of WPSH prediction skill after 1960.
A new global study reveals that nearly 70% of tree species will face significant climate shifts by the end of this century. The study identified exposure hotspots and climate refugia, highlighting the need for urgent conservation actions.
Researchers at the University of Michigan discovered a class of materials with exciting properties for transporting photonic information, including unidirectional transport and defect-free light. The topological insulators' band gap size can be up to 100 times larger than current records, enabling new applications in optical devices.
A clinical trial found that semaglutide, a Type 2 diabetes drug, improved blood sugar levels and weight loss in adult Type 1 diabetes patients who use automated insulin delivery systems. The study showed that 36% of patients taking semaglutide achieved target blood glucose levels and lost at least 5% of their body weight.
Researchers have identified a three-dimensional quantum spin liquid in cerium zirconate, exhibiting emergent photons and fractionalization. This discovery could lead to breakthroughs in superconductors and quantum computing.
A study reveals that metal-organic frameworks (MOFs) can be toxic to mice, causing disruptions in blood cell formation and immune balance. The researchers found that the MOFs suppressed production of certain cells but also triggered a rebound effect, leading to increased inflammation.
A new study found that cannabis edibles with bright colors and labels like "locally made" or "vegan" can make teens think they are healthy snacks. The research suggests that teens are drawn to the design and packaging, seeing them as trendy, natural, and aspirational.
Research by Ramkumar Ranganathan explores how tech companies influence emerging standards through cooperation and competition. Companies that form strategic partnerships and offer benefits to other players in an ecosystem are more likely to shape standards in their favor, according to the study.
A study found that lichen from the Mojave Desert can survive and replicate under extreme solar radiation, previously considered lethal. The discovery suggests that photosynthetic life may be possible on planets exposed to intense UV-C rays, offering new hope for the search of extraterrestrial life.
Dr. Gary Ulaner has been elected vice president-elect of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), committed to advancing nuclear medicine research and expanding educational activities for professionals. As part of his role, he aims to drive growth and funding for training new radiochemistry and physics professionals.
A recent study by IIASA researchers explores the socio-economic potential of India and China, focusing on human capital and labor force quality. The findings suggest that China will maintain an economic lead for most of the next half-century due to its more educated and higher-participating labor force.
Researchers identified five distinct patterns of disordered eating behaviors among college students, linked to anxiety, distress tolerance, and alcohol use. The study challenges the idea that disordered eating only exists in extreme forms, suggesting a need for customized support systems.
A new PET/CT imaging technique visualizes activated fibroblasts in the heart muscle, detecting multiple forms of cardiomyopathy. The method provides valuable insights into disease progression and helps improve risk stratification for patients with non-ischemic cardiomyopathy.
Frontiers expands partnership with ZBMed to share article metadata in OLSPub, increasing visibility and citations. The agreement aims to make peer-reviewed research findable, accessible, and usable globally.
Scientists developed a precise, cost-effective way to make chiral ketones for medicines, agrochemicals, and more using photocatalysis. This approach solves the challenge of reaching remote stereocenters in molecules, allowing for eco-friendly production of valuable chemicals.
A recent study sheds light on the diverse species of soft corals, which were previously difficult to identify due to their variable sclerites. The researchers sequenced DNA from over 4,400 specimens and found that soft corals are more diverse than initially thought, with new discoveries made in regions previously unexplored.
A Korean research team discovered that High Mobility Group Box 1 (HMGB1) plays a critical role in transmitting senescence from aging cells to distant tissues through the bloodstream. Reduced HMGB1 circulates systemically, inducing senescence in remote tissues and impairing regenerative capacity.
Scientists have discovered a link between autism spectrum disorders and congenital heart disease, finding that tiny hair-like structures called cilia underlie the shared biology of both conditions. This study offers hope for early diagnosis and intervention, with potential benefits for children with autism.
A new precision oncology paper presents a case of a 62-year-old man with metastatic colorectal cancer who underwent multiple lines of therapy. The WIN International Molecular Tumor Board proposed personalized treatment plans based on the tumor's unique genetic mutations, highlighting the growing role of precision oncology in guiding th...
Researchers achieved direct measurement of nanometer-scale charge distributions formed at ferroelectric domain interfaces using electron microscopy. This study contributes to a deeper understanding of ferroelectric devices and their performance improvement.
A new molecule called the 'Fusion Superkine' has been created to target and kill glioblastoma cells while stimulating an immune response to prevent recurrence. The treatment, developed by VCU Massey Comprehensive Cancer Center researchers, uses a combination of immunotherapy and targeted delivery to overcome the blood-brain barrier and...
Researchers at Queen Mary University of London found that caffeine works by activating AMPK, a cellular fuel gauge, which helps cells cope with low energy levels. This activation influences cell growth, DNA repair, and stress response, all tied to aging and disease, offering potential health benefits.
Researchers proposed a novel method to improve LoRA-based fine-tuning by adding flexibility to rank allocation within decomposed matrices. This allows for better performance in single-task and multi-task scenarios, while maintaining low computational complexity.
A survey study of California adolescents found exposure to e-cigarette or cannabis posts was associated with increased use of these substances. The study suggests that improving social media community guidelines and policy attention may help prevent youth substance use.
A new study found that moderate caloric restriction can preserve youthful ovarian follicles and reduce age-related tissue stiffness in rhesus macaques. This suggests that lifestyle-based strategies may help delay the decline in reproductive function associated with aging.
A new study reveals that cancer-fighting immunotherapy drugs may offer benefits to organ transplant recipients with advanced cancer when carefully managed. The study found that about one in three patients responded positively to treatment within a year, with improved survival outcomes comparable to the general population.
Researchers found that children's active exploration of their surroundings and use of multiple senses help them learn language quickly. This approach differs from AI systems' passive processing of data, highlighting the need for rethinking AI design.
Researchers at UTA have developed a new power converter system that improves the accuracy of microgrid operations, allowing for more precise control over energy distribution. The technology can connect and coordinate distributed energy resources like solar panels, batteries, and EV chargers, reducing costs and enhancing grid stability.
A novel engineered extracellular matrix derived from mesenchymal stromal cells has been developed to aid cartilage repair. The eECM enhances chondrocyte recruitment, proliferation, and homeostasis, promoting better cartilage regeneration in animal models.
Researchers suggest that brains reach a critical state to learn, remember, and think, which can be measured using fMRI technology. This framework offers a new perspective on neurological diseases like Alzheimer's, which disrupt the brain's ability to maintain criticality.
LINE-1 elements, retrotransposons actively transcribed in zygotes, facilitate chromatin architecture opening and interact with epigenetic regulators to maintain genome stability. Understanding LINE-1 regulation could lead to novel therapeutic strategies in reproductive medicine and age-related disorders.
Researchers identified a key brain region, the ventrolateral periaqueductal gray matter (vIPAG), that modulates pain and emotional responses in threatening situations. By inhibiting specific cells within this region, scientists discovered a potential pathway for better pain relief.
A retrospective study found ESL to be a safe and viable alternative to pneumonectomy for selected patients with centrally located NSCLC. ESL offered better event-free survival compared to pneumonectomy.
A new study analyzes the benefits and trade-offs of urban street trees in Las Vegas, finding that they can create shaded spots nearly 30 degrees Fahrenheit cooler than surroundings. The study also highlights the limitations of tree-cooling benefits in hot, arid climates, where water conservation is crucial.
More than 130 physicians recommend prioritizing beans, peas, and lentils as protein sources in the next Dietary Guidelines for Americans. The recommendation aims to reduce chronic disease and promote healthy weight, while emphasizing plant-based foods over red and processed meats.
Researchers have identified a specific brain circuit, including vasopressin-producing neurons in the paraventricular nucleus, as critical drivers of depressive-like symptoms. Silencing these cells improves mood measures, while activating them exacerbates depressive-like behaviors.
Research synthesizes evidence from dozens of studies on polygenic scores and their clinical implications, revealing consistent patterns that could contribute to personalized psychiatric care. Higher genetic risk for depression correlates with poorer treatment outcomes, including nonresponse to antidepressants and mood stabilizers.
CIK cell therapy improved overall and progression-free survival for patients with colorectal cancer, regardless of disease stage. Serum CEA levels can predict treatment response, paving the way for a simple blood test.
Researchers discovered a novel combination therapy for rheumatoid arthritis that reduces bone destruction by targeting the M6A methylation pathway. The study showed that triptolide and medicarpin combination therapy significantly alleviates arthritis symptoms and delays disease onset.
Researchers found that individual plant defenses target specific pests, but mixtures of defense substances provide better protection against both insects and fungi. The study showed that synergistic effects and diversity in chemical compounds enhance tree effectiveness, answering a central question in plant ecology.