A new study found that increasing apolipoprotein M levels can slow or block progression of age-related macular degeneration, a leading cause of blindness in people over 50. The researchers also found that ApoM triggers a signaling pathway that breaks down cholesterol deposits.
Researchers from The University of Osaka have identified a protein expressed on malaria-infected red blood cells that can hide from the immune system while also activating immune cells to destroy infected cells. This dual function makes the protein an excellent target for vaccine development and treatment.
Researchers discovered how dogroses use larger centromeres to ensure unpaired chromosomes are passed on via the egg cell, enabling a unique reproductive system. This study provides new insights into plant genetics and could lead to more robust crops.
A team of researchers developed a plant-based meat substitute using sunflower flour, which is rich in protein and has a neutral taste. The product's texture and composition were found to be comparable to traditional meat products.
A new study reveals that the combination of an Alzheimer's peptide and a blood protein forms abnormal clots that trigger early Alzheimer's pathologies, including synapse loss and neuroinflammation. The findings provide hope for patients by identifying a promising new drug target: Aβ/fibrinogen complexes.
Researchers discovered that sunlight's oscillating electric field plays a crucial role in enhancing interfacial water evaporation. The stronger the electric field, the faster water evaporates. This finding has implications for engineering more efficient water-evaporation technologies.
Natural climate solutions like wetland restoration and reforestation face various barriers, including lack of funding, insufficient information, and ineffective policies. The study highlights the need for collaborations across sectors and disciplines to unlock their full potential.
The new resource provides a detailed map of blood regulatory variation in South Africans, enabling researchers to interpret genetic variations using genome-wide association studies (GWAS). This innovation has the potential to uncover why people from specific genetic backgrounds may be more susceptible to certain diseases.
A systematic review of hand and wrist injuries among UK dog walkers estimates the annual cost to be over £23 million. Women and older adults are disproportionately affected by leash-related injuries.
Researchers have discovered that multimodal pain integration in the brain significantly enhances overall pain perception when participants are instructed on how to perceive the pain. The precuneus region of the brain plays a vital role in integrating pain information into a cohesive and intensified pain experience.
City of Hope has launched a novel generative AI platform called HopeLLM, which leverages multiple commercial and open-source AI models. The platform enables doctors to spend more time interacting with patients, reducing the administrative burden of new patient onboarding and providing personalized treatment options.
A new research article analyzes 103 scientific studies on microplastics and nanoplastics from food packaging, revealing that normal use of FCAs is a source of MNPs in food. The study highlights the need for harmonized testing and reporting framework to inform policy decisions.
A study found that modifiable risk factors like education, BMI, and hypertension can slow down the spread of Alzheimer's tau tangles. The research suggests that modifying these risk factors can help delay disease progression.
Researchers developed three-dimensionally shaped molecules containing an internal twist, exhibiting properties of organic semiconductors. The molecule was verified to act as an organic semiconductor in an organic field-effect transistor.
Researchers from OIST develop new quantum AI method for image recognition based on boson sampling, achieving highly accurate results without complex training. The approach uses a linear optical network and preserves information, outperforming classical methods in various datasets.
A new study found that individual leopard seals specialize in specific diets, significantly impacting local prey populations. The research highlights the need to examine individual hunting behaviors in apex predators.
A recent study has identified a gene, Zelda, that plays a crucial role in regulating the end of regrowth in fruit fly larvae. The researchers found that Zelda helps control the activity of genes involved in tissue development, revealing a new understanding of the regenerative process.
A study found that a grandmaternal age difference of ≤-9 years significantly increases the risk of pregnancy cardiometabolic disorders. The researchers analyzed data from 2,235 grandmother-mother pairs and discovered a nonlinear association between age differences and CMDs.
Researchers introduce a novel design approach for 3D rotary braiding machines, enabling the production of intricate shapes and complex geometries. The new methodology achieves this by varying the number of incisions and combining different cut-circles, resulting in increased carrier capacity and improved mechanical properties.
Researchers at UCLA have discovered a chromatin-based strategy that enables cells to rapidly produce proteins when nutrients are scarce. This 'priming' mechanism, driven by the MYC gene, allows cancer cells to adapt and survive under metabolic stress.
Researchers developed a new protocol to detect even low levels of T. cruzi parasites in patients, allowing for accurate monitoring of treatment outcomes and potentially leading to more effective drug treatments. The test was tested on human, macaque, and canine subjects, with promising results.
A new preclinical study from Weill Cornell Medicine found that a combination of small molecules extended the survival of transplanted pancreatic islets in female mice, while adding two molecules to the mixture boosted cell survival in male mice. This breakthrough could allow physicians to treat more patients with fewer cells.
Researchers have developed perovskite solar cells that can effectively convert indoor lighting into electrical power. The cells achieved a power conversion efficiency rate of 38.7% under dim light conditions, making them suitable for charging devices in various environments, including offices.
Global survey of 4,351 participants reveals that people in more equal and wealthy societies are more likely to condemn excessive wealth. Moral condemnation is linked to values related to equality, purity, and younger age, suggesting concerns about the corrupting influence of wealth.
Researchers propose a comprehensive solution integrating waste management and carbon sequestration in the coal industry. The study investigates mineralizing low-concentration CO2 using single coal-based solid wastes, significantly enhancing CO2 sequestration capacities.
The American College of Cardiology hosts a Health Equity Summit to address cardiovascular health disparities. Young Indigenous scholars from the NNAYI participate in interactive cardiology workshops to promote equitable healthcare.
This study examines breast cancer incidence trends in older US women by racial and ethnic groups, geographic location, and cancer stage. The analysis reveals differing patterns across age groups, highlighting the importance of considering screening guidelines when analyzing breast cancer incidence rates.
A new type of laser developed by Norwegian University of Science and Technology and partners has solved several problems associated with current-day lasers. The laser can be used in self-driving cars and detects hydrogen cyanide gas in the air with high precision.
A highly aligned and compact MXene film exhibits exceptional electromagnetic interference (EMI) shielding effectiveness across ultra-broadband frequencies. The innovative film, developed by Professor Xuchun Gui's team, demonstrates infrared stealth capabilities making it a promising candidate for advanced stealth applications.
The essay competition aims to expand on Schrödinger's fascination with the connections between quantum theory and biological processes. Entrants will explore questions such as whether life evolved the ability to make use of the counterintuitive properties of the microscopic world, and how this might relate to consciousness.
The WSIS+20 High-Level Event 2025 in Geneva will assess 20 years of using digital technologies for progress and chart the future direction ahead of the UN General Assembly review. The event will tackle critical issues like the digital divide, AI governance, and sustainability.
Naval Research Laboratory internships provide students with cutting-edge research experiences and opportunities for career growth. With real-world applications in national defense and future careers, these programs offer students the chance to advance their innovation.
A dual-protective approach using Botox and an anti-nausea patch significantly reduces salivary gland toxicity in prostate cancer patients undergoing PSMA-targeted radiopharmaceutical therapy. This strategy led to a 30% decrease in PSMA uptake by the salivary glands without affecting the treatment's cancer-fighting efficacy.
A Mount Sinai study found a post-pandemic increase in head and shoulder injuries among female and male youth hockey players, with higher rates of hospitalizations and fractures. The research highlights the importance of safer equipment standards, injury prevention strategies, and education to protect young athletes.
A study by Cornell University research finds that conspiracy believers are dispositionally overconfident and massively overestimate how much others agree with them. They genuinely think themselves to be in the majority, even if they're in a tiny minority, despite being unaware of their fringe beliefs.
Researchers at Osaka Metropolitan University have identified the REDD2 gene, which is activated by metabolic stress and damages pancreatic β-cells, leading to reduced insulin secretion and the onset of diabetes. Suppressing REDD2 expression protects β-cells from damage, even under stress from overeating, preventing the onset of diabetes.
The Western Pacific Subtropical High's (WPSH) predictability has significantly improved over the past century, mainly due to robust oceanic signals from the Indo-Pacific region. Three persistent oceanic predictors have emerged as crucial sources of predictable signals, accounting for 59% of WPSH prediction skill after 1960.
A new global study reveals that nearly 70% of tree species will face significant climate shifts by the end of this century. The study identified exposure hotspots and climate refugia, highlighting the need for urgent conservation actions.
Researchers at the University of Michigan discovered a class of materials with exciting properties for transporting photonic information, including unidirectional transport and defect-free light. The topological insulators' band gap size can be up to 100 times larger than current records, enabling new applications in optical devices.
A clinical trial found that semaglutide, a Type 2 diabetes drug, improved blood sugar levels and weight loss in adult Type 1 diabetes patients who use automated insulin delivery systems. The study showed that 36% of patients taking semaglutide achieved target blood glucose levels and lost at least 5% of their body weight.
Researchers have identified a three-dimensional quantum spin liquid in cerium zirconate, exhibiting emergent photons and fractionalization. This discovery could lead to breakthroughs in superconductors and quantum computing.
A study reveals that metal-organic frameworks (MOFs) can be toxic to mice, causing disruptions in blood cell formation and immune balance. The researchers found that the MOFs suppressed production of certain cells but also triggered a rebound effect, leading to increased inflammation.
A new study found that cannabis edibles with bright colors and labels like "locally made" or "vegan" can make teens think they are healthy snacks. The research suggests that teens are drawn to the design and packaging, seeing them as trendy, natural, and aspirational.
Research by Ramkumar Ranganathan explores how tech companies influence emerging standards through cooperation and competition. Companies that form strategic partnerships and offer benefits to other players in an ecosystem are more likely to shape standards in their favor, according to the study.
A study found that lichen from the Mojave Desert can survive and replicate under extreme solar radiation, previously considered lethal. The discovery suggests that photosynthetic life may be possible on planets exposed to intense UV-C rays, offering new hope for the search of extraterrestrial life.
Dr. Gary Ulaner has been elected vice president-elect of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), committed to advancing nuclear medicine research and expanding educational activities for professionals. As part of his role, he aims to drive growth and funding for training new radiochemistry and physics professionals.
A recent study by IIASA researchers explores the socio-economic potential of India and China, focusing on human capital and labor force quality. The findings suggest that China will maintain an economic lead for most of the next half-century due to its more educated and higher-participating labor force.
Researchers identified five distinct patterns of disordered eating behaviors among college students, linked to anxiety, distress tolerance, and alcohol use. The study challenges the idea that disordered eating only exists in extreme forms, suggesting a need for customized support systems.
A new PET/CT imaging technique visualizes activated fibroblasts in the heart muscle, detecting multiple forms of cardiomyopathy. The method provides valuable insights into disease progression and helps improve risk stratification for patients with non-ischemic cardiomyopathy.
Frontiers expands partnership with ZBMed to share article metadata in OLSPub, increasing visibility and citations. The agreement aims to make peer-reviewed research findable, accessible, and usable globally.
Scientists developed a precise, cost-effective way to make chiral ketones for medicines, agrochemicals, and more using photocatalysis. This approach solves the challenge of reaching remote stereocenters in molecules, allowing for eco-friendly production of valuable chemicals.
A recent study sheds light on the diverse species of soft corals, which were previously difficult to identify due to their variable sclerites. The researchers sequenced DNA from over 4,400 specimens and found that soft corals are more diverse than initially thought, with new discoveries made in regions previously unexplored.
A Korean research team discovered that High Mobility Group Box 1 (HMGB1) plays a critical role in transmitting senescence from aging cells to distant tissues through the bloodstream. Reduced HMGB1 circulates systemically, inducing senescence in remote tissues and impairing regenerative capacity.
Scientists have discovered a link between autism spectrum disorders and congenital heart disease, finding that tiny hair-like structures called cilia underlie the shared biology of both conditions. This study offers hope for early diagnosis and intervention, with potential benefits for children with autism.
A new precision oncology paper presents a case of a 62-year-old man with metastatic colorectal cancer who underwent multiple lines of therapy. The WIN International Molecular Tumor Board proposed personalized treatment plans based on the tumor's unique genetic mutations, highlighting the growing role of precision oncology in guiding th...
Researchers achieved direct measurement of nanometer-scale charge distributions formed at ferroelectric domain interfaces using electron microscopy. This study contributes to a deeper understanding of ferroelectric devices and their performance improvement.
A new molecule called the 'Fusion Superkine' has been created to target and kill glioblastoma cells while stimulating an immune response to prevent recurrence. The treatment, developed by VCU Massey Comprehensive Cancer Center researchers, uses a combination of immunotherapy and targeted delivery to overcome the blood-brain barrier and...
Researchers at Queen Mary University of London found that caffeine works by activating AMPK, a cellular fuel gauge, which helps cells cope with low energy levels. This activation influences cell growth, DNA repair, and stress response, all tied to aging and disease, offering potential health benefits.
Researchers proposed a novel method to improve LoRA-based fine-tuning by adding flexibility to rank allocation within decomposed matrices. This allows for better performance in single-task and multi-task scenarios, while maintaining low computational complexity.
A survey study of California adolescents found exposure to e-cigarette or cannabis posts was associated with increased use of these substances. The study suggests that improving social media community guidelines and policy attention may help prevent youth substance use.