Researchers at Mount Sinai have identified a promising new strategy to overcome resistance to immunotherapy in colorectal cancer. The approach, which restores communication between key immune cells, achieved up to 100% tumor clearance in some models.
The 23rd Carbon Research International Forum highlights engineered biochar's potential in supporting carbon capture, resource recovery, and sustainable industrial development. Recent progress in converting agricultural and industrial residues into high-performance carbon materials was discussed.
A phase 1/2 trial of daraxonrasib, a RAS(ON) multi-selective inhibitor, demonstrated safety and broad activity against RAS-mutant metastatic pancreatic cancer. The drug showed promising signs of activity, with approximately 30% of patients experiencing an objective response and 90% experiencing disease control.
Researchers at the University of Illinois have developed a new theory to explain the emergence of nematic order in solids, resolving a long-standing paradox. The theory suggests that elasticity selectively couples to certain types of nematic modes, suppressing others associated with disorder.
The Ecological Society of America recognizes Stephen W. Pacala and Kenneth M. Klemow with Eminent Ecologist Award and Distinguished Lifetime Service Award, respectively, for their significant contributions to ecological research and public service.
A new study suggests that the rise of continents may have regulated boron levels in ancient oceans, creating a stable environment for life to emerge. The growth of granite-rich continental crust helped stabilize boron concentrations, making it available for use by early life forms.
Researchers found that people taking calcitonin gene-related peptide (CGRP) inhibitor drugs had a 25% lower risk of developing glaucoma than those taking other migraine medications. The reduced risk was only evident in CGRP inhibitors using monoclonal antibodies, not receptor antagonists or gepants.
Researchers from the University of Waterloo have identified four more members of Sir John Franklin's 1845 expedition using DNA samples extracted from skeletal remains. The new discoveries bring the total number of identified sailors to six, providing previously unavailable details about the circumstances and locations of their deaths.
Researchers identify 'hooked hairs' in common beans that form tiny structures to defend against drought and nutrient starvation. These cells help young plants survive long before their mature root systems take shape.
The American Society for Nutrition has appointed Dr. Brian Lindshield as the new Interim Editor-in-Chief of Current Developments in Nutrition (CDN). With extensive experience and a strong record of leadership in academic nutrition, Dr. Lindshield will build on CDN's foundation for continued growth and innovation.
A qualitative study in Hong Kong found that international service-learning produces four main categories of student learning outcomes: interpersonal, personal, civic, and academic. Students reported increased collaboration skills, self-awareness, and global citizenship.
The FoSci Report 2026 examines individual paper-level fraud, coordinated criminal networks, systemic structural failures, and risks to government research. It charts the maturity and gaps in current research integrity practice, arguing that isolated infractions often signal more systemic issues.
Researchers identified functional differences in Segatella strains from different regions of the world. Genomes of Segatella copri with OxyR showed a hundred to thousand times higher oxygen tolerance than those without, suggesting horizontal gene transfer occurred several thousand years ago.
A protein from tardigrades has been found to protect synthetic cell membranes during dehydration, allowing them to survive rehydration. This discovery could lead to a way to store and transport biological microfactories, revolutionizing the production of medicines and other valuable molecules.
Researchers from MIT have developed a more user-friendly and efficient method to identify potential system failures in cloud computing algorithms. The 'MetaEase' technique analyzes an algorithm's source code directly to uncover hidden blind spots that might cause unexpected failures, reducing the risk of costly network outages.
The HALLO project uses real-time acoustic and visual data, vessel tracking, and citizen-scientist reports to track and forecast Southern Resident killer whales' movements. The AI-powered system aims to support faster detection and more reliable classification of whales in shipping lanes.
A new species of long-necked dinosaur, Dasosaurus tocantinensis, was discovered in Northeast Brazil and found to be a close relative of a European species. The dinosaur is estimated to have been around 20 meters long and lived approximately 120 million years ago.
Nicki Washington, a Duke University professor, has been recognized by the Association for Computing Machinery (ACM) for her exceptional commitment to diversifying the computing community. Her mentoring programs have led to increased student success and career opportunities.
A new study reveals that nitrogen enrichment is significantly reducing the abundance and variety of marine life in UK coastal ecosystems. The research found a strong association between higher nitrogen concentrations and a decrease in animal abundance and species richness.
A new CRISPR tool has been developed to eliminate specific cells based on their RNA signature. The nuclease Cas12a2 can target any RNA sequence with high sensitivity and specificity, making it a promising approach for selectively killing cancer cells, virus-infected cells, and unmodified cells.
A new study by UBC researchers found that Indigenous lands consistently protect forests, biodiversity, and carbon stores at levels equal to or greater than government-designated protected areas. The study highlights the importance of securing formal land rights for Indigenous Peoples and funding and resourcing Indigenous stewardship.
A new study reveals that around two-thirds of the Amazon rainforest could shift into degraded ecosystems at 1.5-1.9°C of global warming due to increased deforestation. The study highlights the critical role of the Amazon in regulating moisture recycling and stabilizing the Earth system.
Researchers at Aston University have created an AI-based training method that enables robots to adapt to real-world conditions without extensive data collection. This breakthrough could significantly accelerate innovation in sustainable manufacturing, recycling, and autonomous industrial systems.
A University of Florida study reveals that bacterial blotch in white button mushrooms is caused by a complex of multiple bacteria, not a single pathogen. The discovery could support better diagnostics and more effective, sustainable treatments, helping strengthen mushroom production nationwide.
Researchers at Johns Hopkins Kimmel Cancer Center have achieved a 95% cure rate for sickle cell disease using a reduced-intensity bone marrow transplant regimen, preserving fertility in most patients. The study reports low rejection rates and durable engraftment with minimal immunosuppression.
LabClaw integrates PandaOmics, automated laboratory hardware matrix, LIMS, and multi-dimensional data analysis pipelines to create an end-to-end intelligent closed loop. The system features five types of agents and a Human-in-the-Loop confirmation mechanism for maximizing efficiency without compromising scientific safety standards.
A study by Ohio State University found that certain tree species, such as red maple and northern catalpa, are more resilient to heat and water stress. Urban forests can provide natural cooling, reducing summer electricity usage, but require careful management and investment in irrigation systems.
Researchers at Weill Cornell Medicine have discovered a novel mechanism for sensing cold temperatures in a bacterial protein called SthK. This finding suggests that similar mechanisms may exist in other organisms, including humans, and could provide new insights into disorders related to faulty temperature regulation.
The study identifies nine distinct cellular neighborhoods in the tumor microenvironment, each associated with survival and immunotherapy response outcomes. The blood-based liquid biopsy test could guide treatment decisions for multiple cancer types and treatments.
A new study introduces CIGaRS, a novel approach to derive highly precise estimates of cosmic distances and robust cosmological measurements. This method uses artificial intelligence and neural networks to disentangle the intrinsic effects on supernovae light from environmental factors.
Researchers developed multiplexed MRI technology, enabling simultaneous imaging of signals from multiple molecules in the brain. The technology provides a comprehensive view of the brain's structure, physiology, and molecular processes, allowing for more precise diagnosis and individualized treatment planning.
The 2026 Critical Thinking Challenge recognized submissions from 36 countries highlighting strategies to make critical thinking an everyday habit. Winners received stipends to support research or library needs, contributing to a growing urgency of advancing critical thinking in higher education.
Researchers have developed a technique to analyze DNA from water samples to track species, detect pollution, and monitor ecosystem health. The technology identifies DNA from various organisms, including fish, amphibians, mammals, and even leatherback sea turtles.
The ERASur clinical trial is investigating whether total ablative therapy can improve overall survival in patients with newly diagnosed, limited metastatic colorectal cancer. The study has reached one-third patient accrual milestone, signaling strong momentum.
New research finds that higher temperatures can benefit bumble bees with underground nests by allowing them to spend more time foraging, but may devastate those with aboveground nests due to increased cooling costs. The benefits appear to outweigh the costs, but just a few damaging hours of extreme heat could set a colony back.
A new study reveals how responsive Greenland's ice sheet is to climate change, with widespread methane release linked to an episode of warming around 4,000 years ago. The findings highlight the role of recent ice margin fluctuations on subglacial carbon cycling, with implications for global methane budget assessments.
Elective MRI screenings may lead to false positives, unnecessary surgery, and emotional harm. Experts argue that detecting certain cancers early is not always beneficial, and the scans can exacerbate anxiety rather than improve quality of life.
An international team of astronomers, led by Daniela Calzetti, has observed the 'natal clouds' surrounding young star clusters for the first time. The study reveals that massive star clusters disperse their gaseous shroud faster and light up their galaxy earlier than smaller ones.
A recent study found that failing the glucose challenge test was associated with babies having higher birth weights, a risk factor for future obesity and diabetes. Women diagnosed with gestational diabetes were also more likely to give birth to large babies.
Research reveals how young fish larvae use green-yellow wavelengths of light to navigate Lake Constance's complex environment, but increasing temperatures and artificial lighting pose threats to their survival. Altering light colors in shore areas could mitigate these effects and help protect the delicate ecosystem.
Research finds association between high air pollution and increased risk of post-surgical complications, including sepsis, pneumonia, and surgical wound infection. Higher levels of PM2.5 air pollution above EPA daily limits increase risk by 8%.
Gagliardi's work on multireference electronic-structure theory has led to breakthroughs in catalysis, carbon capture, and water harvesting. Her development of MC-PDFT and LAS methods has facilitated the design of materials that function as molecular sponges.
Researchers used high-frequency ultrasound waves to eliminate viruses such as SARS-CoV-2 and H1N1 by causing structural changes that led to inactivation. The technique uses acoustic resonance, which differs from cavitation, a process used for decontamination.
A rare case of a small bowel GIST harboring concurrent KIT exon 9 duplication and SDHC mutation showed a strong response to high-dose imatinib, despite the presence of the SDHC mutation. Integrated molecular interpretation is crucial in GIST management.
Novin AgriTech received an $174,906 USD grant from the US Department of Agriculture to develop nitrogen use efficiency trait in elite wheat cultivars. The company's platform technology will introduce genetic tools to improve nitrogen use efficiency.
In an experiment, yellow trout grew larger than the wild strain, with averages of 300 grams at 270 days compared to 237-gram range for wild-type ones. The study suggests potential for aquaculture and sport fishing, with color variation leading to different products.
A social media analysis by the University of Helsinki reveals that nature has an important role to play in tourism beyond the beaches, with 25% of photos taken in conservation areas and a third in natural settings. This finding suggests that Central and Southern Europeans tend to focus more on nature than British or Nordic visitors.
The new ALI master's program combines psychology, computer science, and education to prepare students for the intersection of AI, digital technologies, and education. Graduates will have broad career prospects in e-learning, instructional design, and AI-driven product development.
A novel monitoring system has been developed to detect tool wear in machining, delivering 98% accuracy and real-time insights. This innovation uses a flexible tactile sensor to capture detailed images of the cutting edge, enabling manufacturers to schedule replacement at the optimal time.
Research analyzed data from over 300,000 participants to find correlations between physical activity and affective well-being. Positive correlations were found for energy and mood before and after exercise, while calmness showed a negative correlation. Individuals with low well-being particularly benefited from physical activity.
New research examines how sexualized online dating profiles shape viewers' perceptions and relationship intentions. Sexualized profiles are judged more negatively and elicit less interest in long-term relationships. However, adding a human bio can soften the negative effect, particularly for men viewing women's profiles.
Researchers have developed a method to program metamaterials using rotation, enabling the global setting of memory in mechanical systems. By harnessing forces arising from a rotating platform, elastic beams can be made to snap between two stable states, allowing for the storage and retrieval of binary information.
Research on the 'Ndrangheta mafia network reveals that matrimonial ties between lesser-known clans play a vital role in maintaining the entire network's resilience. The analysis found that marriages between less influential families are significantly more critical to the network's cohesion.
Researchers used seafloor video and audio monitoring to capture rare phenomena in a Greenlandic glacial fjord, including fish swimming backwards and making sudden appearances of deep-sea dwellers. The study also revealed the presence of narwhals near the surface, providing new insights into the Arctic ecosystem.
Researchers tracked six NCAA Division I football players over a season and found that non-concussive head impacts correlated with changes to the gut microbiome. The study suggests that even sub-symptomatic head impacts might affect the gut microbiome, both in the immediate aftermath of injury and over a longer time course.
George Newman's book, How Great Ideas Happen, explores the hidden steps behind breakthrough success and reveals that creativity is a method rather than magic. The book, published by Simon & Schuster, draws on cutting-edge research to show how successful innovators approach their work with intention and diligence.
Researchers discovered a membrane complex in microbes that enables efficient conversion of CO2 to biomass without wasting energy. This finding has implications for the understanding of lithoautotrophic microorganisms and their role in extreme habitats.
The Hong Kong University of Science and Technology (HKUST) researchers have developed a revolutionary DNA-guided CRISPR-Cas system that can programmably target RNA molecules, offering improved accuracy in rapid infectious disease testing and advancing antiviral treatments.
A high school teacher participated in a citizen science project to record migration data for Black Skimmers in the Eastern US. The study documents the farthest dispersal for breeding among this species, providing valuable insights into its movements.
RMIT University researchers developed a new method to coat fragile surfaces with a fine mist that acts as a UV shield, allowing normal plant function. The coating absorbs harmful UV light while permitting visible light through, enabling plants to continue photosynthesis.