The study found that coastal bears have reduced genetic diversity and elevated inbreeding, while mountain bears have two distinct, genetically healthy groups. The researchers hope that the genomic data will aid wildlife managers in sustaining a healthy bear population and improving population resilience.
A University at Buffalo breakthrough enables the creation of thousands of detailed protein maps, revealing how disease and treatment reshape tissue biology. This technology has the potential to transform drug therapies by uncovering new therapeutic targets and guiding the development of safer, more effective medicines.
Researchers at UTHealth Houston will study psilocybin-assisted therapy for individuals with co-occurring cocaine use disorder and major depressive disorder. The 12-week study aims to evaluate psilocybin's potential in reducing depressive symptoms and increasing abstinence from cocaine.
Ochsner Children's NICU is part of an international research network dedicated to improving outcomes for infants born at or before 23 weeks' gestation. The collaboration aims to advance research, identify best practices, and support families of extremely premature infants.
Rice researchers have developed an ultraporous material capable of pulling several valuable and rare earth elements from complex waste streams. The material, modified with a molecule called phosphonomethyliminodiacetic acid, allows for the recovery of critical minerals from industrial wastewater, a potential step toward recycling.
Researchers at Rutgers University developed a needle-free mRNA vaccine that protected mice against COVID-19 and flu, offering a potential new delivery method. The vaccine combined a high-pressure liquid jet with adjuvants to strengthen the immune response, and showed improved efficacy and safety compared to traditional mRNA vaccines.
Researchers have discovered that polyion clustering plays a crucial role in liquid-liquid phase separation, challenging decades-old assumptions in the field. This process is essential for the formation of biomolecular condensates, which perform vital tasks necessary for life.
Digital platforms are changing the way young people participate in civic activities, with online spaces providing new opportunities for expression and engagement. Young people from diverse backgrounds are using social media and online tools to raise awareness, mobilize others, and challenge dominant narratives.
Researchers from UC San Diego will join a national effort to accelerate the search for treatments for Alzheimer’s disease. The platform trial will test multiple combinations of natural products, repurposed FDA-approved drugs, and other potential therapies simultaneously using blood-based biomarkers.
Researchers outlined a roadmap for developing state-of-the-art precision diagnostic tests to detect early signs of injury and rejection in xenotransplantation. The framework includes enhanced tissue diagnostics, continuous monitoring, and advanced research platforms to improve long-term outcomes for patients.
Ken Stedman, a renowned virus researcher, has been named an International Collen-Francqui Professor, recognizing his expertise in virus survival and evolution. He will collaborate with four Belgian universities, bringing new opportunities for students and research collaborations.
A study published in Nature reveals that deforestation and wildfires have reversed the Amazon's CO2 balance, rendering it unable to sequester greenhouse gases. The region's carbon balance has shifted, with emissions exceeding absorption by nearly 40% annually.
Researchers found that people who received early rhythm control had an 8% risk of a second stroke, compared to a 14% risk for those who did not receive treatment. Early rhythm control was also associated with a 44% lower risk of stroke and a 28% lower risk of death from all causes.
Jackie Sherrill, a two-time national champion coach, will receive the Paul ’Bear’ Bryant Lifetime Achievement Award in 2027, recognizing his outstanding career accomplishments and dedication to developing young people. The award supports the American Heart Association’ lifesaving mission, honoring coach Bryant’s legacy and celebrating ...
Researchers discovered that iron deficiency during pregnancy can cause lasting changes in brain development, including altered gene expression and myelin formation. These changes can affect cognitive function and may not be fully rescued by iron supplements.
The University of California, San Francisco has been awarded $5M in federal funding to launch a national center to improve dementia detection and management. The center will translate evidence-based approaches into practical tools, training, and technical assistance to bridge the gap between research and practice.
Researchers found that anticoagulant use was associated with a lower risk of ischemic stroke and death in people with AFib who had brain bleeds, with 83% lower risk of ischemic stroke and 80% lower risk of death. Newer anticoagulants were not associated with an increased risk of brain bleeds, while warfarin was.
The Estonian parental benefit has increased the likelihood of having a second or third child, as well as shortened the interval between births. This is particularly true for mothers with higher education qualifications, who receive benefits that compensate for their previous income.
A recent study from the Estonian Biobank surveyed nearly 46,000 participants to explore the causes of side effects from medicines and vaccines. The results show that side effects are common, affecting 29% of respondents, with women more likely to experience them. The study also found that side effects can influence treatment decisions,...
Researchers have discovered magnetic reconnection eruptions and Coronal Mass Ejections near supermassive black holes, similar to solar storms. The 'Neupert effect' was observed in the galaxy NGC 3783, indicating the same physical processes underlying solar storms occur in black hole environments.
Researchers recorded strong and unusual currents in the 2.4-kilometer-long canal, which can amplify water movement under certain atmospheric conditions. The study found that oscillations with periods of several dozen minutes can occur, posing a danger to vessels and coastal management.
Oreejoy's AI-powered wearable device uses pressure sensing, signal processing, and artificial intelligence to assess mobility and provide personalized sensory cues for people with neurological disorders. The startup aims to make effective diagnostics and rehabilitation more accessible, improving quality of life for patients undergoing ...
Insilico Medicine is presenting first-in-human data for AI-designed cancer drug ISM6331, a pan-TEAD inhibitor targeting the Hippo/TEAD pathway in mesothelioma and other advanced solid tumors. The study's results will be discussed at the ESMO Congress 2026.
The New Jersey Supercomputer Initiative (NJSCI) aims to advance research, innovation, education, and workforce development across New Jersey. The initiative will establish a shared supercomputer to support researchers, students, and businesses, enabling them to tackle complex challenges like cancer research and flood risk mapping.
Researchers have identified new predictors of relapse in children with acute lymphoblastic leukemia treated with immunotherapy drug blinatumomab, allowing for more precise treatment tailoring. The study also found genetic subtypes associated with poorer response to treatment and higher risk of relapse.
Drs. Bradley Schlaggar and Amy Bastian, both renowned experts in developmental neuroscience, have been elected to the National Academy of Medicine. Their groundbreaking work has been recognized for its impact on clinical care and public policy. As leaders in their fields, they will advance science and inform policy to improve health ou...
A new study links 12 blood proteins to prostate cancer diagnosed over 15 years after blood sampling, including immune cells and cancer driver genes. The research may help identify men at greater risk of aggressive prostate cancer and inform future studies.
A new study found that nearly one in five young adults in the US experience daily anxiety, with higher rates among women and LGB individuals. The study also revealed disparities in anxiety diagnoses and medication use across different racial and ethnic groups, highlighting the need for targeted support and resources.
A free online program, Mindful Mood Balance for Moms, has been shown to reduce depression relapse among new moms and moms-to-be. The program, which includes audio-guided practices, videos, and advice from peers and professionals, has been found to lower the risk of depression relapse by 26% among participants. The study, published in t...
A case report describes a patient who developed toxic epidermal necrolysis after combination therapy with pembrolizumab and enfortumab vedotin for metastatic urothelial carcinoma. The patient's high-grade urothelial carcinoma and recent radiotherapy may have contributed to the severe skin reaction.
A new AI platform, MAESTRO, has been developed to identify promising drug combinations for overcoming treatment resistance in prostate cancer. The platform uses large language models to analyze scientific knowledge and ranks the most promising candidates, providing a clear biological rationale for experimental testing.
A cold-spray technique has been developed to deposit sensors directly onto human skin and other flexible surfaces, providing strong adhesion and mechanical robustness. This innovation could lead to low-cost, expandable, and high-performing wearable sensors that enable continuous health monitoring and customized healthcare.
Researchers at McGill University found that urbanization is weakening the latitudinal diversity gradient, with tropical cities containing 42% fewer species than nearby natural areas. Preserving green space is a hopeful measure to allow birds and other species to coexist with humans.
Researchers found that mice genetically engineered to have dementia symptoms who received BCG vaccine showed reduced neurofibrillary tangles, sustained immune cell activation, and memory loss compared to untreated mice. BCG vaccination was also linked to reduced inflammation and improved cognitive function in the mice.
Adults create more original and effective ideas, while preschoolers are more confident and enjoy creative activities more frequently. The study suggests that adults' low self-confidence and anxiety inhibit their creativity, whereas preschoolers' enthusiasm and motivation drive their creative pursuits.
A new study published in PLOS One found that forensic specialists can accurately identify individuals with just one or two facial features, with ears being the most useful feature. The experts adapted their strategy depending on the face in front of them, rather than applying one fixed rule.
A study published in PLOS One suggests that attachment anxiety and vulnerable narcissism are associated with problematic social media use. Adults with anxious or fearful attachment styles and high levels of vulnerable narcissism tend to experience higher levels of compulsive social media use.
Researchers identified two common drugs, aspirin and lansoprazole, that may prevent early labor when given together during pregnancy. The study used a digital twin system to simulate the immune system of individual pregnant women and found that the combination had a large effect on delaying labor.
A large US-based study found loneliness to be the strongest factor associated with depression among cancer survivors. The study analyzed data from 70,620 adult cancer survivors and found that those who reported feeling lonely had nearly three times the odds of reporting a lifetime diagnosis of depressive disorder.
Rüppell's vultures exhibit a complex, graded vocal repertoire likely driven by their highly social nature, which may impact conservation efforts. The species' critically endangered status raises concerns about the long-term survival of this unique avian behavior.
Alcohol use during pregnancy has decreased in Finland over the past 35 years, but remains a significant concern. Unaware drinkers, who consume alcohol before realizing they are pregnant, pose a particular risk to fetal health.
Researchers identified a substance that reduces blood vessel lesions in the brain, a disease causing fragile blood vessel structures that can lead to hemorrhages and stroke. The substance, dabrafenib, is already used to treat brain tumors in children and could replace surgery as a treatment option for CCM.
A protein complex called the constitutive centromere-associated network (CCAN) assembles inside the cell, forming a spherical shell-like structure within the nucleus. This structure is essential for faithful segregation of chromosomes and is compromised when CENP-C is removed or prevented from binding to DNA.
Global health experts warn that public health institutions must verify the accuracy of AI-generated content to ensure public health information is trustworthy. The authors argue that knowledge is a public good and that sifting truth from AI-generated content is now a core responsibility for public health institutions.
Female Anopheles mosquitoes employ a 5-step process to bite humans, combining chemical sensing and biomechanical coordination. They bite faster and hunt for blood vessels more quickly than yellow fever-carrying Aedes aegypti mosquitoes, resulting in potentially painful bites.
A new digital twin model suggests that two out of nine FDA-approved drugs have the potential to slow preterm labor. The model, called Simulated Immunome Modeling of Clinical Outcomes (SIMCO), evaluates the impact of eight drugs on immune cell activity in pregnant and non-pregnant individuals.
Research suggests that reduced brain beta wave activity may be a neural marker for schizophrenia, correlating with speech distortion and clinical severity. The study monitored brain activity in patients and controls, finding that beta-band dynamics may signal a potential for targeted interventions.
Researchers have developed a device called Scentronic, which can detect and transmit scents across distances using artificial intelligence and machine learning. The device has the potential to improve nutritional outcomes for patients with sensory challenges and enhance food quality for astronauts and warfighters.
Researchers have developed a new therapeutic approach for SCA3, a rare neurodegenerative disease, by targeting the production of a harmful protein. The approach uses custom-designed drugs to reduce the levels of the disease-causing protein, preserving the normal protein's function.
A new analysis of clinical trial data highlights the delicate balance between preventing graft-versus-host disease and infections in stem cell transplant recipients. The study found that two immune-suppression treatments, cyclophosphamide and tacrolimus, have different effects on T cell immunity and the risk of complications. This rese...
Researchers found that Rüppell's vultures produce 16 distinct call types, using sounds to convey emotions and information. The study's findings could help improve captive breeding programs and shed light on the evolution of communication.
Researchers have created a new antifungal drug, mandimycin M16, which selectively targets fungal ergosterol without disrupting human cholesterol. This breakthrough could lead to safer and more effective treatments for fungal infections, including multidrug-resistant strains.
A new imaging agent JAS239 enables pinpointed removal of lung cancer tumors with near-infrared fluorescent imaging. The agent selectively binds to lung cancer cells and successfully accumulates in excised human lung tumors.
According to a study published in JACC: Advances, cardiac events are responsible for nearly half of all on-duty firefighter deaths in the US. The findings suggest that annual health screenings may miss heart conditions that put firefighters at risk of sudden cardiac death, such as coronary artery disease and heart muscle enlargement.
Researchers found that collective bacterial migration helps them stay ahead of phages, while also enabling phages to infect a fraction of cells near the migrating front edge. This coexistence relies on chemotaxis, or bacteria moving in response to changing chemical levels in the environment.
A pilot study tested an electronic nose, NOS.E, alongside human-remains detection dogs to detect buried human remains and confirm dog signals. The technology tracks chemical changes in decomposition, potentially helping trainers identify whether dogs need more training.
A new study led by UCL researchers found that crocodiles and their relatives followed warm climates wherever they moved, in hot periods spreading as far as Antarctica, and in colder ones retreating to the tropics. This helped them survive the asteroid that killed the dinosaurs.
Researchers discovered that plant proteins like OsNTP4 can assemble RNA chains directly from free nucleotides, challenging traditional RNA synthesis mechanisms. These proteins can generate RNA products without a template or primer, and their activity has been found to be intrinsic to the protein itself.
A European study found associations between air pollution, temperature variability, and blood glucose levels in people without diabetes. Greater exposure to air pollution, particularly PM10 particles, and increases in temperature and temperature variability were linked to higher blood glucose levels.
A team of researchers from Penn State has developed a fluorescent molecular tag that tracks viral RNA and host interactions in real-time, allowing for the study of Zika and chikungunya viruses. The tool, called Mango-II, provides insight into the viral-host cell interaction, a key step to developing effective antiviral strategies.