A study by Radboud University found that users rate chatbots with fluent language as intelligent and useful, even if they provide incorrect information. The research highlights the danger of blind trust in artificial intelligence and suggests that making uncertainty visible is key to protecting users.
A new project aims to use biochemical variables to tailor athletes' rest periods and guide young talent, with a focus on the 2028 and 2032 Paralympic Games. The project seeks to prevent infections and injuries in Paralympic athletes, who are 20 times more likely to contract infections than Olympic athletes.
Researchers found a possible heat source deep inside the Moon, concentrated by tidal forces, which could have contributed to the prolonged magmatic activity of the Moon. The study suggests that tidal heating can produce localized heat sources within the deep lunar mantle, altering temperatures and influencing mantle material movement.
Researchers propose a new approach to harness graphene for solar cells by combining magnetic fields and electrical voltages to separate charge carriers generated by light absorption. This concept could open up new possibilities for solar cells, light sensors, and graphene-based electronics.
Despite decades of research, TB remains difficult to eliminate due to persistent barriers such as poverty, overcrowding, and drug resistance. The book explores how social conditions, healthcare infrastructure, and public awareness can impact TB control.
This review systematically elucidates the interconnected interplay between the tumor microenvironment and macroenvironment, regulating metabolic reprogramming in tumor cells. Emerging precision therapeutic strategies targeting metabolism, such as nanotechnology and exercise, are proposed to develop more effective holistic treatment str...
Research highlights the interconnected regulatory network of programmed cell death pathways in cervical cancer, influenced by HPV-related signaling and the tumor microenvironment. This review proposes targeting multiple pathways, including ferroptosis, to restore cancer-cell susceptibility to destruction and improve treatment responses.
Research in mice reveals that female mice prefer warmer temperatures, while males prefer cooler temperatures, due to differences in ion channels that detect warmth and coolness. These findings may also apply to humans, with women generally preferring warmer rooms than men.
Liquid metal composites can conduct electricity through microscopic cracks, allowing soft electronics to stretch, bend, and flex. Researchers discovered how pressure creates cracks, enabling the metal to flow and form circuits. The findings provide a new framework for designing conductive networks in soft electronics.
Researchers estimate at least 2 billion more dark commutes to school for US children under permanent Daylight Saving Time. The study analyzed school start times, enrollment data, and traffic collision data to find the impact of permanent DST.
A University of Alicante study of 325 fiction series released in Spain between 2020 and 2024 found that TV and VOD platforms are developing new ways of collaborating and sharing content. Weekly releases, which achieve higher ratings on IMDb and Filmaffinity, are favored by audiences.
Researchers hope to enroll over 2,000 stroke patients to test cilostazol's effectiveness in reducing stroke recurrence. The study aims to cut stroke recurrence by 50% and follows Japan's success with similar results.
Ulinastatin shows promise in reducing mortality and hospital stays in ICU patients, particularly in acute pancreatitis and severe acute pancreatitis. However, the evidence is limited by geographic bias, methodological inconsistencies, and limited high-quality trials. Further research is needed to confirm these findings and isolate the ...
A new study found that permanent daylight saving time would increase the risk of fatal car crashes for millions of schoolchildren in the US. The Sunshine Protection Act would lead to over 2 billion pre-sunrise commutes, putting children at risk of early morning crashes.
A KAIST research team developed an antibody candidate that blocks a signal responsible for appetite suppression and weight loss in cancer cachexia. The candidate restored food intake and reduced muscle and fat loss in mouse experiments, demonstrating therapeutic effects.
Researchers developed a new method to investigate interfacial water at material surfaces using X-rays. They successfully separated interfacial water from bulk water using X-ray absorption spectroscopy and data analysis, revealing distinct spectral features and hydrogen-bonding environments.
A new method for fuel cell diagnosis using reduced-data impedance analysis has been developed, enabling near-real-time diagnosis and control. This approach uses a carefully balanced selection of frequencies to capture changes in impedance, improving diagnostic accuracy.
The 'Anyone Can Dock' tool automates molecular docking preparation and provides interactive visualization and analysis for researchers to explore protein-ligand interactions. It supports batch docking and AI-assisted interpretation, making it more accessible for research, education, and scientific exploration.
Participants assigned greater weight to reliable sources but did not use reliability values exactly. They also demonstrated metacognitive awareness of the influence of unreliable information on their decisions. The study highlights the importance of explicit reliability indicators in decision-making.
Researchers discovered molecular rules governing how nanoparticles interact with biological systems, revealing how physicochemical properties shape protein corona formation and influence biological outcomes. The study provides a framework for designing nanomedicines with predictable biological identities.
Chinese experts release new consensus to combat severe dengue, focusing on high-risk populations and core warning signs. The consensus aims to improve early recognition and reduce mortality by standardizing clinical management tailored to China's unique clinical profile.
The Treg-stromal cell axis plays a central role in coordinating immune tolerance, inflammation resolution, and tissue regeneration. Disruption of this axis contributes to autoimmune diseases, and targeting it may restore healthy repair, rather than just suppressing immunity.
A University of Córdoba study analyzes 17 tree species in Córdoba's urban environment to determine their heat tolerance. Native Mediterranean species, such as holm oak and olive, are found to be the most heat-tolerant, while subtropical species are less resilient.
Researchers at Aarhus University found that bacteria can continue producing DNA after death, using a complex machinery involving viruses and enzymes. They developed a method to control the production of specific DNA structures, which could lead to new biological materials and applications in environmental biotechnology.
Agricultural socialized services (ASS) play a crucial role in China's green transformation under dual-carbon goals, with a
The VICTOR-XR project aims to develop intelligent, human-centric Extended Reality technologies that synchronize physical and virtual environments. The project will create immersive experiences that are more realistic, responsive, and trustworthy, enabling systems to identify discrepancies and provide intelligent assistance.
Researchers at the University of Eastern Finland have discovered a new transport pathway for delivering drugs to the brain using the SMVT transporter protein. This breakthrough could lead to more precise treatments for neurological disorders by exploiting the natural transport mechanisms of the blood-brain barrier.
An international review found that indoor plants can remove volatile organic compounds and reduce temperatures by 0.5-4.5 degrees Celsius, but effectiveness varies depending on factors like ventilation and lighting. The review highlights gaps in research and proposes a framework for better measuring and predicting indoor greening effects.
Apilimod, a PIKfyve inhibitor, blocks hepatitis E virus entry by disrupting the lysosomal route used by the virus. The study found that apilimod reduced HEV infection in primary human hepatocytes and animals, highlighting its translational promise.
Research reveals HDAC1/2 sustain alveolar macrophage survival and differentiation via distinct epigenetic mechanisms. HDAC1/2 deficiency leads to severe AM loss, alveolar proteinosis-like pathological changes, and increased susceptibility to influenza virus infection.
A comprehensive review introduces a novel framework for connecting cutting-edge deep learning technologies with core clinical tasks in pathology. The review highlights emerging trends and approaches that tackle the bottleneck of vast amounts of expertly annotated data, allowing AI models to learn from large, unlabeled datasets.
Researchers from PolyU have developed novel metallic materials that achieve unprecedented strength, ductility, and toughness at ultralow temperatures. The
Madagascar's flying foxes, the world's largest bats, are shrinking due to commercial hunting, with the biggest bats disappearing since the 1980s. Researchers found a clear drop in size starting around 1980, suggesting that hunting is the main cause of the decline.
A new patch can measure pulse and blood vessel stiffness using a smartphone camera, providing more accurate cardiovascular health information than traditional methods. This technology has the potential to revolutionize healthcare monitoring in remote areas where specialized equipment is scarce.
Researchers have identified 500 watt-hours per kilogram as an important threshold for the energy density of a solar stratospheric aircraft's battery, making persistent flight viable across many parts of the world. This breakthrough could enable the use of unmanned solar aircraft for repeated monitoring of locations, such as wildfire tr...
Researchers at Yokohama National University developed a photodegradable hydrogel that can be controlled using light, enabling precise control of cell growth and shape in three dimensions. This breakthrough could have significant implications for mimicking dynamic biological tissues and regenerative medicine.
The Suri Center for Gene Therapy will harness UVA's strengths in genetic research and complementary areas to develop safe and effective gene therapy treatments. UVA scientists are exploring precise ways to correct disease-causing gene mutations and develop new approaches to protect the brain from neurodegenerative diseases.
A new study by the University of Gothenburg reveals that hospital sewers promote antibiotic-resistant bacteria, driven primarily by antibiotics such as ciprofloxacin and penicillin-like antibiotics. This finding highlights the need for targeted measures to mitigate the spread of antibiotic resistance.
Dr. Abman's pioneering work transformed the understanding of neonatal lung disease, and his discoveries helped establish inhaled nitric oxide as a life-saving therapy for newborns. He has also advanced pediatric research, education, and clinical care through his leadership of the Pediatric Pulmonary Hypertension Network.
UK experts call for integrated climate and nature risk assessments to reconcile conflicting advice from national security and economic assessments. This approach acknowledges that climate risks don't happen in isolation and can have far-reaching impacts on food production, water supplies, and ecosystems.
Researchers at Tsinghua University Press have developed a β-Si3N4 nanolayer with atomic imaging and bonding-sensitive spectroscopy, providing a reference for studying silicon-nitrogen coordination and electronic states. The study reveals the characteristic ABAB stacking and corner-sharing tetrahedral network of the silicon nitride fram...
A randomized controlled trial found that an ACT-based group intervention improved psychological flexibility, well-being, and meaning in professional lives among individuals facing work challenges. The intervention also promoted participants' values and goals, leading to reduced psychological distress and inflexibility.
Researchers have discovered a promising way to resensitize colistin-resistant bacteria to the antibiotic by combining it with L-arginine, an amino acid. The combination effectively kills strains of E. coli with the mcr-1 gene, which drives resistance, and shows potential as a new therapeutic approach
The CIRM grant renewal supports innovative undergraduate training in stem cell biology, with students receiving special course offerings, hands-on research experiences, and career guidance. The program aims to prepare students for careers in stem cell science and regenerative medicine.
A new Ce3+-doped borosilicate glass scintillator has been developed for multifunctional and environment-adaptive X-ray imaging, offering high efficiency and imaging fidelity. The scintillator delivers IQE of 92.4% and EQE of 85%, with XEL intensity reaching up to 190% of BGO.
A review examines how different embryonic lineages coordinate their activities to construct complex craniofacial organs. It highlights the importance of active interactions among cell populations, including epithelial, mesenchymal, vascular, neural, and skeletal components.
Researchers developed an innovative surface reconstruction strategy to regulate strontium migration and optimize electrode interface in perovskite electrodes. The design achieved lower polarization resistance, faster electrochemical reaction kinetics, and improved thermal compatibility.
A major study found that young children who learn to swim early excel in literacy, numeracy, and following instructions, building transferable skills and dispositions. However, access to swimming lessons is sharply unequal, with cost being a major barrier, especially for low-income and rural communities.
Wiley Analytical Lab offers a one-stop shop for researchers to access trusted spectral data, perform spectral search and identification, and manage analytical datasets. The platform provides a modern online environment for researchers to work efficiently and with greater confidence.
A new research project aims to identify rising cardiac arrest risk before it happens using artificial intelligence and multiple types of health data. The system will combine symptoms, activity tracker data, medical history, and blood tests to provide real-time risk updates.
MIT researchers have developed a magnetic tracking system that can accurately track muscle movement using tiny magnetic beads implanted in the muscle. This system could enable people with certain types of amputations to control their prosthetic limbs more naturally. The system uses pairs of magnets implanted into muscles, which can be ...
Researchers identified age-associated differences in tumor composition and gene activity in younger patients with colorectal cancer, including a higher proportion of connective cells and long non-coding RNAs. These differences may contribute to chemotherapy resistance and increased cancer aggression in younger adults.
Researchers found that C-terminal remodeling in isoleucyl-tRNA synthetase may have refined enzyme activity and reaction speed, enabling faster protein synthesis. The study identified three distinct enzyme clades and found that the removal of a structural region called "INS" may have contributed to this refinement.
Distinguished Professor Kenso Soai and Professor Emeritus Henri B. Kagan were awarded the Nobel Prize in Chemistry 2026 for discovering non-linear effects and autocatalysis in asymmetric organic synthesis, which holds significance for understanding and controlling asymmetric chemical reactions.
Researchers identified distinct cellular and genetic differences in tumors from younger patients, including higher proportions of connective cells and long non-coding RNAs. These findings provide a valuable roadmap for investigating the biology of young-onset colorectal cancer and exploring future treatments.
A newly discovered pathway helps cancer cells selectively produce proteins that drive tumor growth, including KRAS. Targeting the METTL13 enzyme may improve responses to targeted therapies and help overcome treatment resistance.
A Jeonbuk National University study found that PM2.5 exposure accelerates bone marrow stem cell aging and impairs regenerative function in diabetic mice, worsening liver injury and fat accumulation. Inflammation and oxidative stress play a key role in these effects.
Researchers at ISTA found that stars that have gained mass through a merger may become more sensitive to magnetic fields. This is because the mass gain alters the relationship between the star's core and envelope structure, making it more susceptible to magnetic field effects.
A first for basking shark science, the model simulates shark movement and aggregations around the Inishowen Peninsula in Ireland from 1982 to 2018. It shows that social and environmental drivers, not food availability, drive the formation of surface aggregations.
Researchers investigated plant enzymes' selectivity, finding that changes in the active site and other protein sites contribute to precision. The study reveals the evolutionary origin of molecular precision, shedding light on how enzymes adapt for biotechnological applications.