Conduct Disorder is associated with an exceptionally high individual, societal, and economic burden, seven times greater than attention-deficit/hyperactivity disorder. If left untreated, CD can lead to negative consequences, including adult outcomes of antisocial or borderline personality disorder, criminal behavior, and gang involvement.
Research presented at the Society of Nuclear Medicine and Molecular Imaging Annual Meeting found that tobacco smokers have reduced neuroimmune function compared to nonsmokers. This impairment may contribute to compulsive drug use and cognitive dysfunction in smokers trying to quit.
A genome-wide association study found that individuals who attempt suicide carry an increased genetic liability for depression, regardless of their underlying psychiatric disorder. The study analyzed the genomes of over 6,500 suicide attempters and 17,000 non-attempters with major depressive disorder, bipolar disorder, or schizophrenia.
Researchers suggest that cannabinoids may relieve symptoms of OCD and related disorders through targeting the endocannabinoid system. Animal study data and preliminary human clinical trial results support continued pharmaceutical development.
A new review of OCD research by Adam Radomsky and colleagues found that cognitive science has drifted away from treating patients effectively. Instead, the study suggests focusing on individual beliefs about cognitive functioning, which can be worked with in therapy.
A national Taiwanese health database study found people with bipolar disorder were nearly seven times as likely to develop Parkinson's disease as those without the condition. The risk was higher for those hospitalized more frequently, developing the disease at a younger age.
A recent study found that younger parental age significantly increases the risk of ADHD and Tourette's, while older parental age is associated with Autism and obsessive-compulsive disorders. The research provides valuable insights into the complex relationships between parental age and offspring neuropsychiatric disorders.
A study found that 623,000 US parents with opioid use disorder live with children under 18, with few receiving treatment. Meanwhile, healthcare accounts for between 5-15% of premature death variation, with behavioral factors driving more mortality variation.
A study by York University researchers found that individuals with a history of eating disorders, obsessive-compulsive traits, and poor body image are more likely to develop orthorexia nervosa. The review of studies also showed that strict eating schedules, being lacto-vegetarian, or having depression can increase the risk.
An estimated 623,000 US parents with opioid use disorder are living with children under 18, with fewer than one-third receiving treatment. Additionally, four million parents have other substance use disorders with low treatment rates.
Researchers identified 20 new genetic associations with bipolar disorder in a massive study of over 50,000 subjects across 14 countries. The findings highlight the complexity of the disease and its overlap with other psychiatric disorders.
A study by University of Washington researchers identified common triggers for compulsive smartphone use, including waiting for a friend, tedious tasks, and social awkwardness. The team also found that users can find meaning in phone use through apps like meme generators and Kindle, which promote lasting connections to the real world.
A new study found a correlation between strong feelings of responsibility and the development of OCD or GAD in American university students. The research identified three types of inflated responsibility, with personal blame and continued thinking having the strongest link to the disorders.
Researchers report a link between methamphetamine self-administration and imbalance of brain circuits responsible for addiction. Noninvasive brain stimulation may help control compulsive drug use in humans by targeting these circuit imbalances.
Researchers found that sensory cortex signals can cause mice to stop actions, while motor cortex signals can enhance performance. This discovery sheds light on abnormal signaling in neurological and psychiatric disorders.
Researchers developed a new model to explain the evolutionary origins of empathy, suggesting it lies in cognitive simulation. This approach shifts focus from cooperation to a single cognitive mechanism.
Researchers suggest that bi-directional electrodes can both stimulate and record from deep brain structures, enabling closed-loop DBS for movement and psychiatric disorders. This technology could expand treatment possibilities beyond Parkinson's disease.
A new study shows that deep-brain stimulation improves cognitive control by increasing low-frequency brain rhythms in the prefrontal cortex. This finding could lead to more effective treatment plans tailored to individual patients' needs.
Two new Emmy Noether Independent Junior Research Groups at Charité will explore the use of deep brain stimulation to treat neurological disorders and the regulation of immune responses in the nervous system. The groups, led by Dr. Andreas Horn and Dr. Christoph Klose, will receive over €1.7 million in funding for three years.
Butler Hospital has been awarded a $12 million, five-year COBRE grant to focus on clinical-translational brain research. The goal of the Center for Neuromodulation (CCN) is to develop novel treatments for neuropsychiatric diseases by understanding and testing methods to change brain circuit functioning.
Deep brain stimulation (DBS) of the ventral capsule (VC) or anteromedial subthalamic nucleus (amSTN) reduced OCD symptoms to a similar extent, but produced distinct effects on specific symptoms. VC stimulation improved mood, while amSTN stimulation improved cognitive flexibility.
New research funded by the National Institute for Health Research (NIHR) found that 67% of pregnant women in London aged between 16 and 24 years have mental health problems. Anxiety disorders are especially high, with social phobia being particularly prevalent.
Research found social anxiety disorder had strongest association with alcoholism and predicted it over other anxiety disorders. Individuals with social anxiety were at higher risk of developing later alcoholism compared to those with other anxiety disorders.
Researchers identify dysfunctional neuronal connections in OCD patients' brains, particularly affecting the orbitofrontal cortex and primary sensory cortices. This study's findings suggest a deficient inhibitory interneuron system, contributing to the disorder's symptoms.
Scientists successfully demonstrated that electroencephalography can be used to accurately study activity in the deep areas of the brain. This breakthrough technique may lead to better understanding and treatment of diseases such as Parkinson's, Tourette syndrome, and obsessive-compulsive disorders.
A study from the University of Virginia Health System suggests that an antidepressant drug could stop deadly sepsis by regulating inflammation. The researchers tested the drug in a mouse model and found it to be effective, paving the way for potential human trials.
Researchers identified a key neural circuit involved in OCD, including connections between the basolateral amygdala and medial prefrontal cortex. Altering this circuit's activity was shown to impact OCD-like checking behavior, providing new insights into the disorder's pathophysiology.
A Swedish study involving over 500,000 siblings found that lower birth weight was associated with a small but significant increased risk for several psychiatric disorders, including attention-deficit/hyperactivity disorder, autism, obsessive-compulsive disorder, and depression. After controlling for family-related factors, the study fo...
Patients on SSRIs are 40% more likely to develop severe GI bleeding when taking NSAIDs, according to a review in the Journal of the American Osteopathic Association. Physicians should educate patients on recognizing symptoms and monitor for bleeding risks during SSRI therapy.
A new study published in Psychological Review reveals that forming good habits depends more on repetition than satisfaction. The research suggests that our brains tend to stick with repeated actions, even if they're no longer rewarding, and opens up a better understanding of conditions like Obsessive Compulsive Disorder.
A genome-wide study found that copy number variants (CNVs) are more closely associated with a 'schizophrenia-like' bipolar disorder subtype than the broader form of bipolar disorder. This suggests a distinct mechanism underlying the biology of schizoaffective disorder, which shares symptoms with schizophrenia.
Reactive attachment disorder is a social functioning disorder characterized by ambivalence towards comfort and emotional withdrawal. A study of 614 children with RAD found that parents' psychiatric diagnoses increased the child's risk by nine-fold for mothers and six-fold for fathers.
A recent study found that over 40% of youth exhibit obsessive or compulsive behaviors, which can be a red flag for serious psychiatric conditions. Children who experience bad thoughts and intrusive images are more likely to develop depression and suicidal tendencies.
A study found that people taking antidepressants, having post-traumatic stress disorder or anxiety are at risk of developing REM sleep behavior disorder. Men are also more likely to have the condition. Lifestyle factors such as education level, income, smoking status and moderate to heavy drinking habits were also linked to the disorder.
Researchers at UNIGE have pinpointed the brain circuit responsible for addictive behavior in rodents. The study found that a stronger connection between decision-making and reward systems led to compulsive behavior, which could be regulated by artificially increasing or decreasing the activity of this circuit.
A study of 143 young adults found that compulsive social media use and problem drinking share common personality traits, including narcissism and impulsivity. The study suggests targeting impulsiveness and executive dyscontrol may be effective in treating disordered social media use.
Later-born siblings of children with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) are at higher risk of developing the same disorder. The study analyzed data from over 15,000 siblings and found that those born after an older child with ASD or ADHD were more likely to be diagnosed with either condition.
A Caltech-led team of researchers has identified individual neurons that monitor our behavior, catching errors and correcting them quickly. The study provides rare recordings of these neurons, which are involved in error monitoring and have implications for psychiatric diseases like obsessive-compulsive disorder.
Researchers found associations between infections and higher risk of treated mental disorders in children and adolescents. Infections requiring hospitalization or treatment with antibiotics were linked to increased risks of subsequent mental disorder hospitalizations and psychotropic medication use.
Researchers at Cedars-Sinai Medical Center have discovered neurons that signal the detection of errors, offering insights into executive function capabilities and possible treatments for conditions like obsessive-compulsive disorder and schizophrenia. The study also found a single-neuron correlate of self-monitoring for errors in humans.
Despite unmet need for treatment of substance use disorders, telemedicine use for this condition remains woefully underused. The study found that telehealth visits for substance use disorder accounted for only 1.4 percent of all telehealth visits, highlighting a significant gap in access to care.
Researchers analyzed brain scans from hundreds of people with OCD, finding that brains get stuck in a loop of 'wrongness' and have trouble stopping repetitive behaviors. The study identifies specific brain areas and processes linked to OCD, setting the stage for new therapy targets.
A new study using functional MRI found that men with online gaming addiction have altered brain activity compared to healthy controls, particularly in the superior frontal gyrus. In contrast, women with IGD did not exhibit these changes. The study suggests a potential link between gender-specific brain function and online gaming disorder.
About 10% of men and 7% of women reported significant levels of distress and social impairment due to compulsive sexual behavior disorder. A survey study found that 2,325 adults between 18-50 experienced distress and impairment associated with difficulty controlling their sexual feelings, urges, and behaviors.
Researchers found that reducing overall alcohol consumption can lead to fewer people developing an alcohol disorder. The study also showed that men are at greater risk of developing a disorder and are less likely to quit.
Researchers developed a smartphone app to help people with OCD manage their symptoms, reducing obsessive thoughts and compulsive behaviors. After just one week of using the app, participants showed significant improvements in cognitive flexibility and reductions in OCD symptoms.
A recent study from Binghamton University found that the general public struggles to differentiate between obsessive compulsive disorder (OCD) and obsessive-compulsive personality disorder (OCPD). Researchers analyzed phone interviews with hundreds of participants, revealing that those with higher education levels were more likely to r...
The European Problematic Use of the Internet (EU-PUI) Research Network has identified nine main areas of research to address issues such as problem use, health effects, and cultural influences. The network aims to develop evidence-based proposals for improving prevention and treatment strategies.
The Brain & Behavior Research Foundation has awarded over $13.8 million in Young Investigator Grants to 200 promising young scientists studying various psychiatric disorders, including addiction and depression. The grants support innovative ideas for groundbreaking neurobiological research.
A study by the American Psychological Association found that 35% of students from 19 colleges in eight countries reported symptoms consistent with at least one mental health disorder. Major depressive disorder was the most common, followed by generalized anxiety disorder.
Researchers at Columbia University Irving Medical Center have found evidence of how certain transport proteins are working at the molecular level, potentially leading to improved treatments for psychiatric disorders like depression, anxiety, and OCD. The study's findings suggest that a universal feature of these transport proteins may ...
The increasing use of photo-editing technology on social media is changing beauty standards, leading to a rise in self-esteem issues and body dysmorphic disorder. Researchers recommend psychological interventions, such as cognitive behavioral therapy, over surgery to address these concerns.
Nir Grossman's temporal interference (TI) approach stimulates deep brain regions without surgery, offering a new treatment option for brain disorders. TI uses multiple electric fields to target specific brain areas, improving spatial resolution and non-invasiveness.
A study from Binghamton University found that individuals living in areas with lower sunlight exposure may have a higher risk of developing obsessive-compulsive disorder (OCD). The researchers suggest that reduced morning light exposure could disrupt the internal biology and external light-dark cycle, leading to increased OCD symptoms.
Scientists have created a new way to selectively turn neural circuits on and off without surgery. By combining ultrasound waves, gene therapy, and synthetic drugs, researchers can noninvasively control specific brain regions and cell types. This technique has implications for treating neurological and psychiatric conditions.
Researchers at UC Davis will investigate human brain's attention systems with higher resolution than ever attempted, aiming to understand and treat attention disorders. They plan to use combined fMRI and EEG methods to measure brain activity in volunteers.
Researchers at Salk Institute discovered a hierarchical system in the brain that organizes learned behavior, offering new insight into neurological diseases. The study found three levels of control in neuronal activity, providing potential therapeutic targets for disorders like Parkinson's disease and obsessive-compulsive disorder.
A recent study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that only 22% of American youths who received treatment for anxiety disorders stayed anxiety-free over a six-year period. The study also revealed that 30% remained chronically ill and 48% relapsed, highlighting the need for more dur...
Researchers developed a computational model that found serotonin boosts learning rates in mice, particularly in slow decision-making systems. The study suggests a possible link between serotonin and cognitive behavioral therapy, which is often effective when combined with SSRIs.
Researchers discovered that activating GPR139 reduces alcohol intake and restores pain sensitivity thresholds in alcohol-dependent mice. This finding suggests a potential new approach for treating alcohol use disorder.