A phase 2a trial of 82 people investigated whether cannabidiol (CBD) is safe and can help people with cannabis use disorder reduce cannabis use. The study found that daily prescribed medical-use CBD use can cause reduction in cannabis use among people with cannabis use disorder.
A study by Boston Medical Center found that 29% of private post-acute care facilities in Massachusetts explicitly discriminated against hospitalized individuals with opioid use disorder, rejecting their referral for admission. The rejections were often due to a substance use disorder diagnosis or treatment with buprenorphine or methadone.
Researchers discovered a range of co-existing conditions in patients with fragile X syndrome and premutation disorder. Lower FMRP levels are associated with emotional processing issues, including mood disorders, anxiety, and psychotic features. The study calls for more research on psychosis and FMRP levels, as well as greater awareness...
A study found that individuals with bipolar disorder who switched to high-deductible health plans experienced a moderate decrease in nonpsychiatrist mental health outpatient visits. However, rates of psychiatrist visits, medication use, emergency department visits, and hospitalizations remained unchanged.
Patients with multiple family members suffering from severe mental disorders require more intensive treatment, but respond equally well as those without a family history. The study found that family mental health affects patients' lives beyond the disorder itself.
A nationwide study reveals that only 2% of hospitalized patients with opioid use disorder receive life-saving medications during and after discharge. This finding highlights a critical gap in care, as evidence-based treatment is rarely prescribed in US hospitals.
Physician-scientists at Beth Israel Deaconess Medical Center identified two clusters of depressive symptoms responding to distinct neuroanatomical treatment targets in patients undergoing TMS. These findings may facilitate personalized TMS therapy for depression and other psychiatric disorders.
Researchers have discovered a potential treatment for synaptotagmin-1-associated neurodevelopmental disorder, a rare condition affecting neurotransmitter release. By analyzing mutated proteins and their effects on neuron communication, the team identified a familiar drug, 4-AP, as a possible therapeutic option to alleviate symptoms.
Research from Uppsala University finds individuals with social anxiety disorder exhibit distinct personality traits, including high neuroticism and introversion. The study identifies three clusters of personality subtypes, suggesting varying causes and treatment needs for the disorder.
A survey of U.S. primary care physicians found that nearly one-third do not view medication treatment for opioid use disorder as effective, despite strong research evidence and clinical guidelines emphasizing its life-saving benefits. The study also revealed low support for policies to remove prescription barriers and increase insuranc...
A new study estimates that nearly 3 million US children have visual-spatial learning disorder, affecting math, executive function, and fine motor skills. The disorder is often overlooked due to its name and lack of consensus among physicians on diagnosis and treatment.
A new hereditary disease, FACAS, has been discovered that causes a cold-induced urticarial rash in patients exposed to temperatures below 15°C. The researchers found that the disorder is caused by a previously unknown mutation in the 'Factor 12' gene.
Research identifies lower concentrations of neuropeptide arginine vasopressin in infant cerebrospinal fluid of those diagnosed with autism spectrum disorder. This finding suggests a potential biomarker for early detection and prediction of the disorder.
A new neurodegenerative disorder has been discovered in children, characterized by developmental regression and severe epilepsy. The disorder is caused by a variation in the NRROS gene and appears to require two copies of the defective gene.
A new study by the University of Turku suggests that premature babies are three times more likely to be diagnosed with reactive attachment disorder. The risk is also associated with low birth weight and monitoring in a Neonatal Intensive Care Unit.
Early-career family physicians with maternity care and buprenorphine prescribing skills are undertrained, posing risks for pregnant women with opioid use disorder. Family medicine residencies must prioritize training in treating substance use disorder during pregnancy to address rising maternal mortality rates.
A new study published in Clinical Infectious Diseases shows that treating opioid use disorder with medications within 30 days of discharge from the hospital due to injection drug use-related endocarditis improves health outcomes. Those who received medication had a reduced risk of overdose and rehospitalization within a year.
A new study shows that individuals with opioid use disorder who receive medication and residential treatment after detox have lower mortality rates. The research highlights the importance of ongoing treatment to increase survival chances.
A new study by Salk researchers finds that altered potassium levels in neurons may contribute to mood swings in bipolar disorder. The study reveals two distinct types of neurons in people with bipolar disorder who respond to lithium and those who don't, highlighting the need for personalized treatment approaches.
A study published in Psychotherapy and Psychosomatics found that individuals with eating disorders use exercise as a coping mechanism for depressive mood and negative thoughts. Exercise can temporarily improve their mood, but this effect is short-lived, leading to a vicious cycle of increased exercise.
A new IU study found that Medicaid expansion has increased access to substance use disorder treatment, but it did not lead to a detectable increase in hiring attempts to expand the treatment workforce. The study analyzed job postings in the sector from 2010-2018 and found shifts in the types of occupations being hired.
Researchers at the Salk Institute have discovered a unique pattern of DNA damage that arises in brain cells derived from individuals with macrocephalic form of autism spectrum disorder. The observation helps explain what might go awry in the brain during cell division and development to cause the disorder.
A UCLA-led study found that family-focused therapy can delay new and recurring bipolar symptoms in children and teens. The treatment, which involves teaching patients and families better communication skills, resulted in 77% of adolescents recovering from initial symptoms within four years.
States with Medicaid work requirements have higher opioid overdose death rates and fewer substance use disorder treatment facilities. Increasing access to evidence-based opioid addiction care is crucial for individuals with these conditions.
A new University of Toronto study reveals that seven in ten Canadians with a history of generalized anxiety disorder are free from the condition, with 40% achieving excellent mental health. Social support and spiritual coping also play significant roles in recovery.
A study from Johns Hopkins Medicine suggests that being around dogs from an early age may have a health benefit, decreasing the chance of developing schizophrenia as an adult. However, no significant link was found between dogs and bipolar disorder or cats and either psychiatric disorder.
Researchers found that a single infusion of ketamine combined with outpatient behavioral therapy helped individuals with alcohol use disorder abstain from drinking for several weeks. The study suggests that ketamine may improve motivation and reduce demoralization after a lapse, leading to better abstinence rates.
Scientists at Case Western Reserve University have identified a critical role for the Cullin 3 gene in brain development, contributing to autism spectrum disorders (ASD) and schizophrenia. The discovery sheds light on the mechanisms underlying these complex conditions, potentially paving the way for new treatments.
Researchers created manganite nanowires with controlled quenched disorder, revealing enhanced magnetoresistance. Quenched disorder plays a significant role in complex oxide systems.
Researchers found that using diet pills and laxatives for weight control increased the odds of receiving a subsequent first eating disorder diagnosis by 80% and 320%, respectively. The study calls for policies to restrict access to these products, including banning their sale to minors.
Children born to mothers with eating disorders face increased risks of premature birth, microcephaly, and hyperemesis during pregnancy. The study also found that the risk varies depending on the type of eating disorder and whether the mother has an active or previous eating disorder.
A study of over 200 patients with bipolar disorder found that high levels of inflammation, as measured by C-reactive protein, were significantly linked to poor cognitive performance. This suggests a potentially modifiable risk factor for cognitive deficits, and highlights the importance of addressing inflammation in treatment.
A study from Columbia University's Mailman School of Public Health found that recreational cannabis legalization led to a 26% increase in past-month marijuana use and a 37% rise in cannabis use disorder among adults aged 26 and older. The researchers also observed a small increase in cannabis use disorder among adolescents.
After recreational marijuana legalization, past-year cannabis use disorder among 12-17 year-olds increased from 2.18% to 2.72%. Frequent marijuana use among 26+ year-olds also increased, from 2.13% to 2.62%, and those with cannabis disorder rose from 0.90% to 1.23%. No association found among 18-25 year-olds.
A study published in the British Journal of Pharmacology found that kratom may be effective in reducing alcohol consumption but carries risks of addiction and side effects. The researchers suggest alternative therapies could provide safer treatment options for individuals with alcohol use disorder.
A new study from the University of Bristol found a significant association between generalized anxiety disorder at age 18 and harmful drinking three years later. The research used data from the Children of the 90s cohort to investigate the relationship between anxiety, drinking motives, and alcohol use.
A recent NIH-funded study suggests that exposure to acetaminophen during pregnancy may increase the risk of attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in children. The study found that higher levels of acetaminophen exposure were associated with a significantly increased risk of both conditions.
Researchers discovered shared brain circuit abnormalities in patients with mood and anxiety disorders, enabling targeted interventions. These findings hold promise for improving outcomes for individuals with major depressive disorder, bipolar disorder, post-traumatic stress disorder, and anxiety disorders.
Research suggests that the prevalence of cannabis use disorder has decreased among frequent users between 2002-2016, with significant declines observed across all age groups. This decline may be attributed to changes in social attitudes and perceptions of risk associated with cannabis use, as well as increased legalization.
A study published by the American Psychological Association found a significant association between borderline personality traits and increased cardiovascular risk. Researchers recommend screening patients with BPD for cardiovascular risks to address potential health concerns.
A recent study found that both professional esports players and recreational video game players are at risk of developing internet gaming disorder when they use gaming as a means of escapism. The study, which surveyed over 4,300 gamers, suggests that escapist tendencies can be a common predictor of gaming disorder in both groups.
A new study found that military veterans with post-traumatic stress disorder (PTSD) are more likely to experience a rare sleep disorder called REM sleep behavior disorder (RBD), which is also linked to an increased risk of developing neurodegenerative conditions like Parkinson's disease. Researchers hope that identifying patients with ...
A new UBC psychology study found that biological siblings of people with gambling disorder exhibit markers of increased impulsivity and risk-taking. The research suggests people with gambling disorder may have pre-existing genetic vulnerabilities to the illness.
The study found that the supply of queens and packaged bees is sufficiently elastic to absorb demand increases due to colony collapse disorder, leading to no significant price hikes. Beekeeper methods of offsetting winter losses, such as splitting hives, remained relatively inexpensive and effective in meeting pollination contracts.
A new study suggests that opioid treatment medications can increase the number of teens who remain in treatment and decrease their opioid use. Medications like methadone, buprenorphine, and naltrexone have shown promise in treating severe opioid use disorder in adolescents.
A review of the literature suggests that adolescents with severe opioid use disorder can be treated with these medications as part of a comprehensive treatment plan. However, further research is needed to understand optimal treatment duration and retention rates.
A meta-analysis of 40 studies reveals that individuals with psychiatric disorders such as major depressive disorder, bipolar disorder, and borderline personality disorder exhibit heightened impulsivity. The study suggests a continuum between impulsive and self-controlled decision-making across different disorders.
A study published in Biological Psychiatry found that relatives of patients with schizophrenia and bipolar disorder have unique brain abnormalities, despite symptom overlap. The findings suggest that familial risk for these disorders influences brain development already early in life.
A new study reveals that circular Rep-encoding single-stranded DNA viruses have acquired their genetic components through complex evolutionary processes. The findings show that these viruses are 'obsessive borrowers', appropriating genetic material from various sources, including bacterial and eukaryotic cells.
A team of researchers at Ruhr-Universität Bochum has shown that the supposed disorder in the HMGA1a protein is not disorder after all. The protein adopts dynamic, more compact structures that depend on its phosphorylation state. This discovery could lead to new therapeutic strategies for cancers caused by HMGA1a.
A survey of 93 people with 3q29 deletion syndrome reveals a distinct pattern of social disability and anxiety, even without an autism spectrum disorder diagnosis. The study indicates a higher risk of autism spectrum disorder at a similar level to schizophrenia, particularly for females.
Researchers found small increases in nonmedical prescription opioid use and slight decreases or no change in prescription opioid use disorder among nonmedical users. Medical marijuana laws had little impact on individual-level opioid outcomes, suggesting insufficient policies to reduce misuse.
A large-scale data study conducted by Swansea University researchers has identified early warning signs of eating disorders, including higher rates of other mental disorders and prescription medications. The findings may enable GPs to detect these conditions earlier, leading to better outcomes for patients.
Conduct disorder is a highly impairing psychiatric disorder that requires improved diagnosis and treatment. The condition is associated with a seven times greater health burden than ADHD and is linked to depression, anxiety, and substance abuse in children. Correct diagnosis and management can improve patient well-being and life chances.
Conduct Disorder is associated with an exceptionally high individual, societal, and economic burden, seven times greater than attention-deficit/hyperactivity disorder. If left untreated, CD can lead to negative consequences, including adult outcomes of antisocial or borderline personality disorder, criminal behavior, and gang involvement.
Research highlights patchy care, delayed diagnosis, and lack of guidance for treating first-time manic episodes. Effective treatments are available but often overlooked, exacerbating symptoms and worsening health outcomes.
A UCSF-led study found 22% of young men and 5% of young women engage in disordered eating behaviors to gain weight. These behaviors can lead to muscle dysmorphia, heart failure, depression, and social isolation if left unchecked.
A study examined which conditions were considered illnesses by different groups, revealing a significant difference between psychiatrists and non-medical professionals. The results underscore the importance of understanding societal attitudes towards mental health, as these perceptions influence resource allocation and stigma.
A genome-wide association study found that individuals who attempt suicide carry an increased genetic liability for depression, regardless of their underlying psychiatric disorder. The study analyzed the genomes of over 6,500 suicide attempters and 17,000 non-attempters with major depressive disorder, bipolar disorder, or schizophrenia.
Researchers are using novel experimental approaches to understand autism spectrum disorder, including studying networks of interacting genes and protein regulation. These studies aim to identify common molecular mechanisms underlying the disorder, which could lead to new treatments.