A new study found that non-invasive brain stimulation using transcranial direct current stimulation (tDCS) can significantly reduce bulimia symptoms, including urge to binge eat and concerns about weight. The treatment showed promise in improving cognitive control over compulsive features of the disorder.
A study published in Appetite found that children with more eating disorder symptoms at age nine also had a higher number of symptoms at age 12. The research identified three key areas to monitor for early intervention: body dissatisfaction, depressive symptoms, and earlier onset of symptoms.
Patients taking antidepressants for depression are more likely to report gastrointestinal and cardiovascular side effects if they also have panic disorder, according to a new study. Co-occurring panic disorder is associated with an increased risk of worsening depressive symptoms.
A new NIH-funded study aims to test ways family members can maintain their health while caring for relatives with bipolar disorder. Researchers will match caregivers with tailored self-management techniques, including breathing exercises and training in self-help skills, to reduce stress and improve overall health.
A study by Michel Laroche and Marcelo Nepomuceno found that people with certain world views react differently to thoughts of death. Compulsive shoppers are more likely to buy when thinking about mortality, while anti-consumers resist consumption more strongly.
Research highlights the complex etiology of psychiatric polypharmacy, which can increase the risk of adverse effects and mortality. However, certain populations may benefit from combination therapy, emphasizing the need for tailored prescribing strategies to improve treatment efficacy.
A recent study published in JAACAP found that obesity among adolescents with bipolar disorder is associated with increased illness severity, including more suicide attempts and psychiatric hospitalizations. However, the study also found that overweight adolescents with bipolar disorder are not more common than their peers.
Research found promising initial evidence that specific neuroimaging markers can help predict the response to psychotherapy in patients with depression or anxiety. Neuroimaging markers such as activity in the amygdala, anterior insula, and anterior cingulate cortex may indicate which patients are more likely to benefit from psychotherapy.
The Light Plate Apparatus (LPA) brings optogenetics within reach of most biology labs with low-cost, easy-to-use hardware and software. Researchers can now incorporate optogenetics testing into their labs without extensive engineering or programming training.
A study of over 1 million male teens found higher resting heart rates above 82 beats per minute and high blood pressure associated with later development of obsessive-compulsive disorder, schizophrenia, and anxiety disorders. Lower heart rate and blood pressure were linked to substance use disorders and violent behavior.
Research found a strong correlation between high resting heart rate and blood pressure with an increased risk of obsessive-compulsive disorder (OCD), schizophrenia, and anxiety disorders. Men with higher resting heart rates were 21-69% more likely to develop these mental health conditions.
A study of 522 children found that those born to parents with schizophrenia or bipolar disorder scored higher on a behavior checklist and were at increased risk for anxiety, ADHD, and neurocognitive problems. The children also came from families with lower social status and more adverse life events.
The Brain & Behavior Research Foundation has awarded $13.7 million in NARSAD Young Investigator Grants to support groundbreaking neurobiological research on psychiatric disorders affecting one in five people. The grants aim to improve treatments and develop prevention strategies for mental illnesses.
A new therapeutic target has been identified for the treatment of compulsive binge eating, targeting the brain receptor TAAR1. Activation of this receptor shows promise in reducing maladaptive feeding behaviors and blocking addiction-like behavior to junk food.
A study of 2.4 million Swedish children found perinatal factors such as maternal smoking, breech birth, and preterm birth associated with a higher risk of developing OCD. The findings suggest an important role for environmental factors in the development of the disorder.
Girls with ADHD are at higher risk for multiple mental disorders, including anxiety (37.7%), depression (10.3%), and oppositional defiant disorder (42%). Effective treatments, such as therapy and positive reinforcement, can help manage symptoms and prevent severe adult impairments.
A study by Georgia State University researchers found that yoga can reduce worry, the main symptom of Generalized Anxiety Disorder. The findings suggest that yoga has promise in helping people with this condition reduce their symptoms and improve quality of life.
A new study led by TSRI researchers found that a compound can specifically inactivate alcohol-linked neurons, reversing compulsive drinking behavior in rats. The findings suggest a potential new approach to treating alcohol dependence.
A new study found a correlation between microscopic brain damage and impaired cognitive performance in patients with symptomatic carotid artery disease. The researchers used diffusion tensor imaging to assess white matter tract skeleton mean diffusivity, which showed the closest correlation with cognitive impairment.
A follow-up study finds that bipolar adolescents are at higher risk for substance use disorder and smoking five years later. The presence of conduct disorder, particularly when combined with bipolar symptoms, significantly increases this risk.
Researchers at Salk Institute created a comprehensive map of the striatum, a lesser-known brain structure that controls movement. The study reveals how patch and matrix neurons coordinate diverse functions, shedding light on long-standing questions about neurodegenerative diseases like Parkinson's.
A new study by TSRI and NIH scientists found that hypocretin levels may contribute to cocaine addiction. Blocking hypocretin activity reduced compulsive drug-seeking behavior in rat models. The research suggests a potential role for the hypocretin system as a pharmacological target for treating cocaine addiction.
Researchers found similar brain impairments in children with autism spectrum disorder, attention deficit hyperactivity disorder (ADHD) and obsessive compulsive disorder (OCD). The study linked these impairments to symptoms that occur across different conditions.
A study by University of New South Wales and Italian researchers found a significant delay in diagnosing bipolar disorder, with an average delay of almost six years. This delay can lead to missed opportunities for early intervention and reduced severity of episodes.
Researchers found that the direct and indirect pathways in the basal ganglia play a crucial role in controlling actions, with the direct pathway sustaining action and the indirect pathway allowing switching between actions. This new model could have therapeutic implications for treating diseases like OCD and ADHD.
A study found that individuals with anorexia nervosa who struggle with insight have abnormal brain connectivity in regions involved in error detection and conflict monitoring. This can lead to poor decision-making and a reduced ability to recognize the danger of their behavior, making recovery more challenging.
A Duke University study found a single chemical receptor in the brain responsible for OCD symptoms in mice. The receptor, mGluR5, was found to be overactive in mice with Sapap3 gene deletion, which mimics human OCD. When blocked, symptoms abated immediately.
A six-fold increase in diagnosed sleep disorders among US veterans has been reported, with post-traumatic stress disorder (PTSD) experiencing the largest rate increases. The study found that veterans with cardiovascular disease or other chronic conditions also experienced higher rates of sleep disorder diagnoses.
Researchers from Scripps Florida have discovered a link between bipolar disorder and the striatum, a brain region involved in motor planning and reward perception. The study identified 14 genes differentially expressed in bipolar patients compared to non-bipolar controls, suggesting a causal role in the disorder.
Researchers have identified 84 potential inherited gene mutations that may contribute to severe forms of bipolar disorder. The study used advanced genome sequencing techniques to analyze DNA from 36 family members with the disease, finding rare genetic variations that were overrepresented in those with bipolar disorder.
USC scientists have created a comprehensive map of the dorsal striatum, a part of the brain responsible for motor learning and coordination. The study identifies 29 distinct areas and hubs that coordinate complex limb movements, potentially leading to new treatments for autism and Huntington's disease.
Mothers who develop postpartum depression often experience protective risk factors, but once their babies are born, they show more obsessive-compulsive symptoms. Women who had depression before becoming pregnant were more likely to experience hypersomnia and difficulty falling asleep.
A new study using optogenetics has increased long-term memory in mice with fear disorders, such as phobias and post-traumatic stress disorder. The technique, tested in two mouse populations, improved memory recall and reduced fear responses, offering potential therapeutic targets for these conditions.
Researchers discovered that endocannabinoids reduce activity in the OFC, promoting habit formation. This study suggests that targeting the brain's endocannabinoid system may alleviate suffering in disorders involving habitual control.
Researchers found that endocannabinoids quiet neurons in the orbitofrontal cortex, leading to an over-reliance on habit. The study suggests a new therapeutic target for OCD and addictions: treating the brain's endocannabinoid system to restore goal-directed action.
Researchers at Concordia University have discovered a more effective way to treat anxiety disorders by incorporating safety behaviors into therapy. The study found that patients who used new safety behaviors during exposure therapy had better outcomes than those who relied on traditional safety behaviors.
A national survey of over 34,000 adults found that individuals with bipolar disorder are equally likely to develop anxiety as depression after experiencing an episode of mania. This study may lead to a broader clinical definition of bipolar disorder that includes episodes of mania along with anxiety or depression.
A study of over 20,000 participants found that videogame addiction is associated with attention deficit/hyperactivity disorder and depression. Younger, single men are particularly at risk, using gaming as an escape from unpleasant feelings and restless bodies.
The Brain & Behavior Research Foundation has awarded $3.9 million in NARSAD grants to 40 mid-career scientists from 30 institutions worldwide to support basic research, new technologies, and next-generation therapies for schizophrenia, major affective disorders, and other serious mental illnesses.
A new mouse model has been developed to study anorexia-like conditions triggered by a combination of genetic risk, stress, and dieting. The model closely resembles the conditions leading up to anorexia in humans, particularly in adolescents, and may help identify prevention and treatment strategies.
Common Parkinson's disease medications can cause impulse control disorders such as pathological gambling, compulsive buying and binge eating in some patients. Alternative treatment strategies include adjusting medications, deep brain stimulation and cognitive behavioral therapy.
A study of the Canadian Forces Mental Health Survey found that child abuse experiences accounted for 28.7% of the burden of illness, while Afghanistan-related deployments contributed 8.7%. Child abuse was linked to various mental disorders, including post-traumatic stress disorder and panic disorder.
A recent study found that 2.5% of adults experienced marijuana use disorder in the past year, with 6.3% having met the diagnostic criteria at some point in their lives. Only 7% of those with past-year disorder received any treatment.
A new Scripps Research Institute study has identified specific genetic variations associated with increased susceptibility to bipolar disorder and other conditions. The research focuses on a gene called PDE10A, which produces proteins that regulate intracellular levels of cAMP, influencing biological processes like learning and memory.
Researchers identified genetic pathways exacerbating severe canine compulsive disorder in Doberman pinschers, sharing behavioral hallmarks with human OCD. The discovery could lead to better therapies for obsessive compulsive disorder in people, as serotonin receptor genes and stress tolerance loci were found to be strongly correlated.
Cocaine users exhibit hyperactivation in the ventral striatum, a region critical for reward processing, and display anomalous activation profiles in the prefrontal cortex. Structural differences, including hypertrophy of key brain regions, contribute to the development of compulsive behaviors and difficulties in controlling impulses.
A recent study published in the Journal of Intercollegiate Sport found that varsity athletes with high obsessive passion towards their sport are more likely to accept the use of performance-enhancing drugs. In contrast, athletes with high harmonious passion tend to have conservative attitudes towards PEDs.
A study published in The BMJ found that internet-based cognitive behavioural therapy (CBT) can effectively treat body dysmorphic disorder, reducing symptom severity and depression. Participants who received BDD-NET showed significant improvements compared to those receiving online supportive therapy.
A recent analysis found that using paroxetine during the first trimester of pregnancy may increase newborns' risk of congenital malformations and cardiac malformations. The study suggests that the benefits of antidepressants during pregnancy are questionable, and non-use or alternative treatments like psychotherapy may be a better option.
Naturally occurring brain wiring changes can help patients at high genetic risk of developing bipolar disorder avoid the illness. Researchers found that resilient siblings showed additional changes in brain wiring within networks involved in emotional processing, which may help them avoid the disease.
Researchers identified 13 inherited sleep and activity measures linked to bipolar disorder, including later waking times and shorter periods of activity. The study provides clues to the genetic nature of the disorder and potential new approaches for prevention and treatment.
Researchers found hyperconnectivity between brain networks in adolescent boys with Internet gaming disorder, which may help them respond to new information but also increase distractibility and poor impulse control. The study provides insights into the neural basis of compulsive video game play.
A USC study surveyed 3,310 ninth-grade students and found that those with moderate mental health problems who vape e-cigarettes have emotional and behavioral issues midway between smokers and non-vapers. E-cigarette use has tripled among teens in recent years, with flavors like Skittles enticing young people.
Recurrent Strep A infections may lead to autoimmune neuropsychiatric disorders in children through a previously unknown route. Immune cells triggered by the infection travel along odor-sensing neurons to reach the brain, causing inflammation and promoting neuroinflammation.
Research found a heightened risk of subsequent mania and bipolar disorder in adults treated with certain antidepressants, including SSRIs and venlafaxine. The peak age for diagnosis was among patients aged 26 to 35, with an annual risk of 1.2%.
A new Canadian guideline provides recommendations for diagnosing fetal alcohol spectrum disorder (FASD), a neurodevelopmental disorder resulting from prenatal alcohol exposure. The guideline recommends counseling women and their partners about abstinence during pregnancy, screening pregnant women for alcohol use, and conducting complet...
Researchers used optogenetics, fMRI, and electrophysiology to track brain activity and show how stimulation frequencies affect arousal. They found that altering deep-brain circuit firing frequency dramatically alters forebrain activity and alertness levels.
Obese children show increased brain activity in areas linked to impulsivity and obsessive-compulsive disorder when exposed to food smells. In contrast, normal-weight children exhibit brain connections between taste processing and reward anticipation.
Researchers at the University of Cambridge found that people with compulsive sexual behavior seek out new sexual images more frequently than others. They are also more susceptible to environmental cues linked to sexual images, which can trigger their addiction.
Researchers found that adding exposure and response prevention therapy to treatment regimens significantly improved symptoms in patients with OCD who had not responded to medication. The study also showed significant increases in insight, quality of life, and social function after just eight weeks.