Researchers at KAIST have identified a neural circuit in the hypothalamus governing obsessive behavior towards non-food objects in mice. The MPA-PAG circuit modulates object craving and facilitates hunting behavior, allowing for controlled mammalian behavior with optogenetics.
A new Yale study analyzed 14 million newspaper articles from 1900-2016 to find that each war brought a new term for what are now known as PTSD symptoms. This lack of clear terminology may have slowed clinical and scientific progress on the disorder.
Researchers found higher levels of vitamin D binding protein in children with bipolar disorder compared to those without mood disorders. The study suggests a potential blood test to confirm bipolar diagnosis, which could improve care and reduce the current 10-year average lag time.
A new study published in Pediatrics found that children with both autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are at a higher risk of developing anxiety and mood disorders. The study, which analyzed data from over 3,300 children, revealed that these psychiatric conditions were more prevalent in ol...
A study found that symptoms of inattention, hyperactivity, and conduct disorder are associated with increased errors in a driving simulator and self-reported risky driving behaviors in adolescents. Researchers suggest that understanding mental health factors can help reduce risky driving behaviors among novice teen drivers.
A new study reveals that nearly one in three military personnel meet criteria for nightmare disorder, with trauma-related nightmares occurring in 60% of them. Those with nightmare disorder had an increased risk of other sleep and mental health disorders, including PTSD, depression, anxiety, and insomnia.
A study published in the Brazilian Journal of Psychiatry found that nearly one-quarter of 12-year-olds from public schools had a psychiatric disorder, with depression and attention-deficit hyperactivity disorder being the most common diagnoses. Investing in socio-economic inequality prevention and preventing violent events during child...
A study published in JAMA Psychiatry found that lithium treatment significantly reduces the risk of rehospitalization for individuals with bipolar disorder, with a 30% lower risk compared to no treatment. Long-acting injections of antipsychotics also showed promise, reducing the risk by 30%.
A study found that female patients with anxiety disorder react more quickly to a heart attack and arrive at the hospital sooner, potentially improving their chances of survival. In contrast, men with anxiety disorder also showed a positive trend in seeking medical attention earlier, although the effect was not statistically significant.
The study found that only 27.6% of individuals with anxiety disorders received appropriate treatment, with the remaining cases receiving inadequate care. The low treatment rate is attributed to factors such as lack of awareness, health system weaknesses, and stigma surrounding mental illnesses.
A new study published in Biological Psychiatry found that bipolar I and II disorders have different biological causes, with stronger family clustering for each subtype. The research also identified distinct gender differences and genetic correlations between the subtypes.
Scientists at Bielefeld University confirm the presence of a previously unknown genetic defect 'MPS III-E' causing progressive blindness and inner ear hearing impairment in patients. Biochemical studies revealed that the disorder is caused by an enzyme deficiency, which can be treated with biotechnological enzyme replacement therapy.
Regular sleep disruptions associated with difficulty disengaging attention from negative information, leading to intrusive thoughts and increased risk of depression and anxiety. Researchers found that inadequate sleep contributes to the persistence of negative thoughts, making it harder for individuals to ignore them.
A new study found that cigarette smoking rates increased among individuals with substance use disorders, including hallucinogens and heroin, while decreasing among those with cannabis use disorders. More than half of individuals with a substance use disorder reported cigarette use in the past month, compared to 18% without a disorder.
A University of Michigan team has identified seven distinct phenotypes in people with bipolar disorder, each with unique biological mechanisms and external influences. These findings have the potential to help patients, clinicians, and researchers better understand the condition.
Researchers at UTHealth found that individuals with bipolar disorder exhibit accelerated epigenetic aging, which may explain why they are more prone to age-related diseases and have shorter lifespans. The study suggests that lifestyle factors such as diet, exercise, and substance use can contribute to this premature aging.
The article proposes mental health and disorder recommendation programs to strengthen policy implementation in the Greater Mekong Subregion. The programs aim to address regional disparities and promote mental wellness by building international mental health networks.
A comprehensive new report examines three systems used to understand mental health disorders: ICD, DSM, and RDoC. The report finds that these systems have similarities and differences in how they classify and conceptualize mental disorder, highlighting the need for a nuanced approach that considers individual factors.
Researchers from Aarhus University discovered that patients with Rapid Eye Movement Sleep Behaviour Disorder (RBD) lack dopamine and experience brain inflammation, which may lead to Parkinson's disease. This study provides new insights into the early stages of Parkinson's disease development.
Researchers found that heart rate variability measured by an electrocardiogram indicated whether subjects had major depression or bipolar disorder. Patients with bipolar disorder had higher blood levels of inflammation biomarkers than those with major depression.
Researchers used induced pluripotent stem cells to explore the causes of autism, revealing that abnormalities in astrocytes may contribute to the disorder. Astrocytes play a crucial role in the development and function of the nervous system.
A new study by Rice University found that nearly a quarter of Mexican immigrants living near the California-Mexico border without legal authorization have a mental disorder, with major depressive disorder, panic disorder, and generalized anxiety disorder being the most prevalent. The study's findings highlight the need for culturally s...
Researchers developed a test to predict bitter pit disorder in stored Honeycrisp apples, which can save growers millions of dollars annually. The test analyzes calcium levels in fruit peels and indicates whether the disorder will develop.
Researchers at McLean Hospital discovered a unique brain training program that improves cognitive skills in individuals with bipolar disorder. The study found significant improvements in cognitive performance, memory, and visual learning, with sustained benefits six months after treatment.
A genetic variant associated with multiple psychiatric disorders is linked to changes in a brain network that may increase an individual's risk of developing bipolar disorder or schizophrenia. The variant affects the expression of the SNAP25 protein, impacting information processing between brain regions involved in regulating emotions.
Researchers have identified networks of genes related to autism spectrum disorder (ASD) that may also be involved in cancer, potentially leading to new treatment options. The study used a computational technique to account for gene interactions, revealing genes that could affect similar pathways.
Researchers created mice lacking ankyrin-G protein, displaying hyperactivity and reduced anxiety. Lithium treatment reversed these behaviors, mirroring human bipolar disorder symptoms.
A new study published in Anesthesia & Analgesia found that delaying a child's tonsillectomy did not lower the risk of developing a mental disorder. Children under 5 who underwent minor surgery with anesthesia had a 26% increased risk of later diagnosis with a mental disorder.
Researchers at the University of Cincinnati have discovered a link between acid-sensing receptor TDAG8 and panic disorder symptoms. The study found significantly increased levels of TDAG8 in patients with panic disorder, correlating with symptom severity and treatment response.
A study by researchers at Mount Sinai identified a brain mechanism that makes siblings of bipolar patients resilient to the disease. The brain can adapt to its biological risk, opening new avenues for research on enhancing resilience.
A new study by Drexel University found that opioid users are 50% more likely to receive treatment and have it paid for by insurance under Obamacare. The study analyzed data from the National Survey on Drug Use and Health, showing a significant increase in access to care and insurance coverage since the ACA's implementation.
A new study reveals that managerial support can help workaholics avoid attending work when sick and address work-family conflict. By recognizing the harm of presenteeism, managers can train themselves to develop protective factors against this phenomenon.
A study published in Neuropsychopharmacology found decreased brain pH levels in mouse models of schizophrenia, bipolar disorder, and autism spectrum disorder. The research suggests that lower brain pH may be an underlying pathophysiology for these mental disorders.
Research suggests that individuals with a family history of bipolar disorder may experience faster biological aging. The study found that patients treated with lithium had longer telomeres, which could help reverse age-related changes. This association may explain the higher rates of aging-related diseases among bipolar disorder patients.
Researchers at UCLA have discovered a link between brain wave frequency and nonverbal IQ in children with autism. The study found that lower peak alpha frequency corresponds to lower non-verbal IQ, suggesting a potential biomarker for detecting autism severity.
A Seattle-focused study found that young people with chronic depression are at a higher risk of developing a cannabis-use disorder. The study suggests that preventing or reducing chronic depression during early adolescence could lead to a reduced prevalence of cannabis use disorder.
A randomized clinical trial found tramadol extended-release to suppress opioid withdrawal more effectively than clonidine, and similarly to buprenorphine. The study suggests tramadol ER as a promising medication for opioid use disorder treatment, but notes the need for further research.
Researchers found differences in immune system factors between men and women with bipolar disorder, particularly in zinc levels associated with depression severity in women. This study suggests that biological changes in the body could be used to diagnose the disease and tailor treatments differently for men and women.
Researchers have identified genetic factors that cause congenital myotonic dystrophy, a debilitating muscle disorder. They developed specialized mouse models to test potential drug therapies and found severe RNA misprocessing as a major cause of the disease.
A new study in Biological Psychiatry found that people with Tourette's disorder and chronic tic disorder are over four times more likely to die by suicide than the general population. Persistent tics into adulthood were a strong predictor of suicide risk, with patients nearly four times more likely to attempt suicide.
A study published in the Journal of Neuroinflammation found that measuring two proteins in the blood can accurately diagnose autism spectrum disorder in approximately 75% of children. The diagnostic accuracy increases to 82% when both proteins are measured together.
A study analyzing 9.7 million young people found that only 26.8% received medication for opioid use disorder within six months of diagnosis. Younger people, females, and non-Hispanic black and Hispanic youth were less likely to receive medications.
Researchers at the University of Cincinnati developed a genetic fuzzy logic AI that predicted treatment outcomes for bipolar patients with 100% accuracy, surpassing conventional models. The AI, called LITHIA, can analyze vast amounts of data to identify the best treatment options, offering new hope for those affected by bipolar disorder.
A novel gene defect has been identified as the cause of a severe skin blistering disorder in Central Asian Shepherd dogs. The defect, found in the COL7A1 gene, leads to the absence of collagen, causing fragile skin and blisters.
A recent study by Columbia University's Mailman School of Public Health found that approximately half of adults with anxiety or depression also experience chronic pain. Chronic physical conditions were most common among individuals with mood disorders, followed by respiratory diseases and cardiovascular disease.
Researchers at Lancaster University found that online self-management support for parents with Bipolar Disorder improves parenting skills, child behavior, and reduces parenting stress. The intervention combines self-management strategies with mood management to promote consistent parenting.
A recent study has identified the molecular mechanism behind lithium's effectiveness in treating bipolar disorder, providing a clear path to developing new diagnostic tests and therapies. The research, led by Sanford Burnham Prebys Medical Discovery Institute, utilized human induced pluripotent stem cells to map lithium's response path...
A recent study by UTHealth researchers has identified genetic alterations in children at high risk for bipolar disorder, which can be modulated by stress. The findings suggest that these genetic markers may contribute to the increased risk of developing bipolar disorder in children chronically exposed to stressors.
A study has identified four brain-expressed genes as likely risk factors for Tourette disorder, including WWC1, FN1, CELSR3, and NIPBL. De novo variants in these genes were found to have a significant association with the disorder, suggesting a potential target for effective treatments.
A global consortium has created the first map of bipolar disorder's impact on the brain, revealing clear differences in brain regions controlling inhibition and emotion. The study found significant thinning of gray matter in patients with bipolar disorder, particularly in areas responsible for emotional regulation.
The Heinz C. Prechter Bipolar Research Program has received a $5 million gift commitment from the World Heritage Foundation - Prechter Family Fund, which will double donations to bipolar disorder research. The program aims to identify effective solutions for people with bipolar disorder through long-term studies and DNA analysis.
New studies published in JAMA Network report no increased risk of autism spectrum disorder and attention-deficit/hyperactivity disorder among children exposed to antidepressants during pregnancy. The research suggests alternative explanations for previous findings may be responsible.
A team of researchers has identified the cause of a rare genetic disorder known as dystonia, which affects 70,000 people in the UK. The study found that mutations in the hippocalcin gene lead to overactivation of specific calcium channels, causing abnormal neuronal signaling and movement disorders.
A recent study published in the American Journal of Psychiatry found that valbenazine can significantly reduce tardive dyskinesia symptoms in patients with schizophrenia, schizoaffective disorder, and mood disorder. The medication showed a 50% improvement rate compared to the placebo group.
Heroin use has increased five-fold among Americans since 2001, with significant rises in white males with low income and education. The prevalence of heroin use disorder also increased, particularly among younger individuals, with whites ages 18-44 experiencing a more pronounced increase than non-whites and older adults.
New UCLA research reveals that clinical interviews about daily activities can help doctors identify pregnant women at risk of postpartum depression. The study found that only 11% of women with a history of major depressive disorder developed postpartum depression, significantly lower than previous studies
Scientists at the Salk Institute have developed a new method to predict which individuals with bipolar disorder will respond to lithium therapy. Using a system trained on electrical firing patterns of neurons from six patients, the method achieved 92% accuracy in classifying responders and nonresponders.
A study by NYU's Steinhardt School of Culture, Education, and Human Development found that teens with PTSD symptoms misidentify sad faces as fearful. Teens with conduct disorder tend to interpret sad faces as angry.
Recent immune research advances the understanding of autism spectrum disorder (ASD), highlighting the role of immune dysregulation in its development. Therapies targeting the immune system may also have benefits beyond ASD, such as preventing attention-deficit/hyperactivity disorder.
Research validates PLCgamma1 as a promising candidate gene for bipolar disorder, linking it to manic-like behavior and synaptic imbalance. The study reveals that loss of PLCgamma1 from forebrain leads to behavioral abnormalities and manic episodes.