A study found that supplementing with HMB before surgery improves liver regeneration in animals by preserving energy function and improving the quality of recovery. The supplementation was shown to have a beneficial effect on mitochondrial function and metabolic performance, even after it was discontinued.
A ten-year experiment with European seabass found that the initial high proportion of male births under intense heat was reversed by the third generation, with more females being born. The study's findings suggest a compensatory mechanism that could counteract the harmful effects of warming on fish populations.
Researchers found that adding small amounts of brown seaweed flour to gluten-free cookie recipes significantly increases phenolic compound content, antioxidant activity, and protein content. The study suggests potential use as a functional ingredient in the food industry.
A molecule called Sindecam-4 (SDC4) on cell surfaces may help prevent tumor progression and metastasis. Silencing the receptor halted accelerated growth of tumor cells, causing them to resume responding to natural programmed cell death mechanisms.
The Oropouche virus has infected over 9.4 million people in Latin America and the Caribbean since 1960, with 5.5 million cases reported in Brazil alone. The disease causes fever and symptoms similar to dengue, leading to serious complications like meningitis and microcephaly.
Researchers at UNICAMP identified a variable that combines visceral fat and muscle radiodensity from CT scans to predict patients at higher risk of unfavorable disease progression. This new marker, called VMD, complements traditional tumor staging, paving the way for personalized treatment approaches.
Researchers suggest that the evolution of toxin accumulation in poison dart frogs occurred gradually, with at least four phenotypes representing stages in this process. These phenotypes include species that sequester alkaloids or modify them, while others metabolize toxins without accumulating them.
Researchers at the University of São Paulo found that climate change increases soybean production by 50% but reduces nutritional quality due to altered composition. High carbon dioxide levels, high temperatures, and drought also affect amino acid content, starch, and protein content in beans.
A new anti-inflammatory molecule has shown promising results in protecting neurons and delaying disease progression in mice with Parkinson's disease. The study, published in Neuropharmacology, found that the Ac2-26 peptide mitigated neuroinflammation and protected against cell death.
A study at the Federal University of São Paulo found that only a fraction of copper and magnesium from Brazil nuts and cashews is absorbed by the human body. The researchers used an in vitro gastrointestinal digestion assay to assess bioavailability, which differed from bioaccessibility.
A study of 6,165 Salmonella samples identified 128 types of toxins, including 45 previously unknown. The toxins act in competition among microorganisms and may inspire antibiotic development and biotechnological applications.
Researchers have developed a biopolymer that encapsulates the fungus Beauveria bassiana, increasing its viability from 69% to 85% after five months of storage. The biopolymer, made from carboxymethylcellulose and aluminum, provides a more sustainable alternative for releasing the bioinsecticide.
Researchers detected pathogenic species of Sporothrix in the internal organs of mammals, birds, and reptiles that were killed by vehicles on Brazilian roads. The study reveals a new reservoir for fungi, highlighting the need for surveillance.
Researchers found that Brazilian savanna wetlands can store significantly more carbon than previously thought, with an average storage capacity of 1,200 tons per hectare. This is due to the slow accumulation process favored by oxygen-poor water-saturated soils, with some areas storing carbon for up to 20,000 years.
The HUG-CELL project aims to identify couples at risk of transmitting recessive genetic disorders and Fragile X syndrome. The initiative will create a large genetic database for Brazil to determine the prevalence of hereditary genetic diseases and develop 'risk calculators' based on the diversity of the Brazilian population.
The Ipiranga Museum in São Paulo will utilize 3D laser scanning technology to create a digital model of the renovated building and establish an information management system for preventive maintenance. The project aims to analyze the behavior of the building following restoration work, identify anomalies, and prevent costly interventions.
Researchers at Viva Bem have developed an AI method that identifies states of anxiety with high accuracy using smartwatch data. The technology aims to provide a layer of proactive monitoring for users, alerting them to recurring anxiety episodes and recommending specialist consultation.
Researchers from UNICAMP and USP describe three new species of moths in the Eois genus, named after Orixás from Candomblé and Umbanda traditions. The study improves understanding of Lepidoptera diversity in Brazil and ecological interactions with Piper plants.
Researchers at the University of São Paulo have developed nanoparticles that deliver therapeutic RNA molecules directly to skin cells, silencing genes responsible for chronic inflammation. This precision nanomedicine approach holds promise for treating complex diseases like psoriasis and vitiligo.
Brazil needs to build separation and refining facilities, master permanent magnet production, and address environmental risks. The country's capacity to meet global demand for rare-earth magnets is currently only around 6%.
The partnership aims to consolidate and expand scientific partnerships in strategic areas, with a focus on artificial intelligence, biotechnology, and energy transition. FAPESP and UKRI will co-chair the Transatlantic Platform and explore joint research centers to advance this exceptional partnership.
A novel biomaterial containing jackfruit latex, pomegranate peel extract, and simvastatin shows promising efficacy in treating periodontitis. The material has adhesive properties, allowing for targeted release of therapeutic compounds, and has been shown to promote regeneration of periodontal tissues.
Researchers analyzed tumor samples from over a thousand patients and found that TP53 gene mutations can worsen prognosis and reduce effectiveness of targeted therapies. The study suggests incorporating genetic testing into public health services to guide personalized treatment choices.
The symposium aims to consolidate and expand partnerships in strategic areas such as energy transition, artificial intelligence, and health. The event will facilitate cooperation among researchers from São Paulo and the UK, with a focus on joint funding opportunities.
Recent studies indicate an extension of dry seasons and changes in rainfall patterns in the Amazon, with some predictions surpassing decades' projections. Climate models show intensified water deficits, particularly in southwestern regions under high greenhouse gas emission scenarios.
The study suggests that massive galaxies formed through violent mergers, leading to a rapid burst of star formation and the growth of supermassive black holes. This process prevented these galaxies from producing new stars for over a billion years, leaving them as quiescent galaxies.
The São Paulo School of Advanced Science on Nonlinear and Quantum Photonics will bring together leading global specialists in nanophotonics, nonlinear optics, and quantum optics. The event will provide two weeks of intensive learning on key topics including quantum optics and information.
A Brazilian study analyzed data from over 5,000 territories and 1,924 anuran amphibian species to determine the biodiversity of these habitats. The research found that two main theories about island biodiversity do not explain the richness of anuran amphibians on their own, but rather are complementary factors.
A recent study using whole-genome data reveals the complex history of South American Indigenous peoples, with genetic diversity higher in Central America and the Southern Cone. The research also identifies a third wave of migration from Mesoamerica around 1,300 years ago, which challenges previous views about Indigenous groups.
A new study reveals that metabolic dysfunction in offspring is caused by excess microRNA in sperm from obese fathers. After weight loss, these molecular marks disappear, and offspring develop normally. Research suggests that interventions promoting health and longevity may trigger an increase in this enzyme expression.
Researchers linked duration and severity of depression to differences in functional brain connections, paving the way for personalized treatments. Changes in brain networks, particularly the Central Executive Network and Default Mode Network, were associated with varying degrees of depressive symptoms.
Researchers identified genetic changes in the virus that explain why it wasn't detected by existing tests. The new diagnostic method shows promise for future suspected cases with greater accuracy.
Research reveals that rivers are exceeding their resilience limits, leading to local extinctions, food chain collapses, and permanent changes in services provided by rivers. A paradigm shift is needed from reactive actions to proactive large-scale strategies for watershed management and river resilience.
A recent study found two cocoa cultivars with superior performance in resisting the witches' broom fungus, which decimated crops in southern Brazil. The research suggests that combining genetic improvement and nutritional management is the most sustainable strategy for cocoa production in the Amazon region.
A systematic review and meta-analysis found that creatine supplementation does not significantly reduce inflammatory markers in the body. Despite its ergogenic effects on physical performance, creatine's anti-inflammatory properties are limited to specific contexts, such as intense exercise.
Researchers developed a mathematical method to calculate the most economical travel routes between celestial bodies. The new route requires significantly less fuel consumption than previously described paths, with potential cost implications for space missions.
Researchers have created biodegradable sensors that can monitor pesticide presence and other factors in plants. The sensors are made from carbon ink and cellulose acetate bioplastics, allowing for non-destructive and rapid detection of pesticides.
A study found that even low levels of particulate matter in the air increased hospitalization risk for men with kidney diseases. Men aged 19-50 were most at risk, with prolonged exposure to high concentrations increasing the risk of chronic kidney disease and acute kidney injury.
Scientists have created an electrochemical strategy capable of producing amines directly from molecular nitrogen, eliminating complex chemical processes and reducing energy consumption. The new method uses a catalyst to facilitate the conversion of N2 into nitrogen-containing organic molecules.
Researchers discovered that genes linked to neuronal communication are also altered in immune cells of patients with depression, reinforcing the systemic nature of the disease. This finding paves the way for developing blood tests to identify and diagnose depression, as well as new treatment approaches targeting inflammation.
Reanalysis of 540-million-year-old microfossils from Brazil reveals they are not animal traces but rather communities of fossilized microscopic bacteria and algae. This finding suggests that invertebrates may not have existed or left marks during the Ediacaran period due to limited oxygen levels.
A new species of long-necked dinosaur, Dasosaurus tocantinensis, was discovered in Northeast Brazil and found to be a close relative of a European species. The dinosaur is estimated to have been around 20 meters long and lived approximately 120 million years ago.
Researchers used high-frequency ultrasound waves to eliminate viruses such as SARS-CoV-2 and H1N1 by causing structural changes that led to inactivation. The technique uses acoustic resonance, which differs from cavitation, a process used for decontamination.
In an experiment, yellow trout grew larger than the wild strain, with averages of 300 grams at 270 days compared to 237-gram range for wild-type ones. The study suggests potential for aquaculture and sport fishing, with color variation leading to different products.
Researchers developed a new photonic material using lead iodide, enabling high-speed data transmission in the terahertz frequency range. The material confines light within submicrometer regions, paving the way for integrated photonic circuits that could replace or complement electronic circuits.
Scientists discover atmospheric connection between African dust aerosols and Amazonian nutrient cycles. Researchers use daily black carbon measurements and global meteorological data to investigate variability of atmospheric cleanliness in the Amazon.
The São Paulo School of Advanced Science in FoodOmics aims to advance understanding of omics technologies in food and nutrition. The event will feature keynote lectures, workshops, and interactive sessions with renowned researchers from around the world.
A study published in Translational Psychiatry suggests that low-dose minocycline may help treat panic disorder by reducing inflammation in brain cells. The antibiotic was found to have a similar effect to the commonly prescribed medication clonazepam, with lower doses required to achieve similar results.
Researchers found that melatonin increased vascularization and reduced apoptosis in ovarian grafts, improving their viability. The study used an absorbable sponge to apply melatonin to autologous ovarian tissue transplants in rats, revealing its potential as a treatment option for fertility preservation in young cancer patients.
A study published in Scientific Reports confirms the anti-viral properties of galloylquinic acids extracted from Copaifera lucens leaves, inhibiting viral entry and replication. The substance's multi-target mechanism reduces the likelihood of resistance developing, making it a promising therapeutic candidate against COVID-19.