The project aims to analyze core replication complexes crucial for repairing damaged DNA and understanding cancer initiation and progression. The study may lead to insights into human health and disease, particularly cancer susceptibility.
Researchers at Georgia State University have been awarded a $2.4 million grant from the National Institutes of Health to study the impact of diabetes on cardiovascular health. The team aims to develop new therapies targeting damaged mitochondria to prevent or delay Type 2 diabetes.
The School of Public Health will compare the SafeCare model, teaching parenting skills, with standard case management approach in a three-year project assessing parent and child well-being and reducing maltreatment risk. The study aims to provide information for better-informed health decisions.
A study published in the Journal of Labor Economics found that merit-based scholarships, such as Georgia's HOPE Scholarship, reduce the likelihood of students earning STEM degrees. The research suggests a significant drop in the probability of students majoring in STEM fields, with effects being more dramatic for male students.
Researchers at Georgia State University found that severe polyinhalant users had double the rate of head injuries and higher rates of mental illness diagnoses. Polyinhalant use was also associated with delinquent behavior starting younger, highlighting the need for prevention and intervention strategies.
A Georgia State University researcher is investigating the impact of emulsifiers on gut microbiota, leading to chronic inflammatory diseases and metabolic syndrome. The study aims to determine how emulsifiers alter the intestinal tract's relationship with beneficial bacteria.
A recent study by Georgia State University and other institutions reveals that chimpanzees' brain structures are associated with various personality traits. The research found correlations between gray-matter volumes in specific brain regions and personality traits such as openness, extraversion, and dominance.
Researchers found that monkeys and humans perceive the Delboeuf illusion in a similar way, with both species misjudging dot size depending on outer ring size. This suggests that primates share similarities in their perceptual systems, making them an appropriate model for studying human perception.
Researchers found that adult survivors of pediatric posterior fossa brain tumors performed significantly lower on standardized clinical tests of working memory, and had increased blood-oxygen level dependent activation in prefrontal regions.
Researchers at Georgia State University develop an oral drug using microparticles and natural herbal molecules to target colon inflammation in ulcerative colitis. The curcumin-loaded microparticles show potential as a scalable drug carrier for efficient clinical treatment of this chronic gastrointestinal disease.
Cancer patients who receive chemotherapy treatment for a sustained period have heightened levels of reactive oxygen species (ROS), which correlates with drug resistance. The study proposes a measure of relative ROS levels under normal conditions to help determine if patients are becoming resistant to cancer drugs.
Single grandparents caring for grandchildren are at a higher risk of poor physical and mental health compared to single parents. The study found that solo grandparents fare worse in four critical health areas: physical health, mental health, functional limitations, and health behaviors.
A Georgia State University study found that 10% of mothers in southern Louisiana experienced chronic, persistent depressive symptoms two years after Hurricane Katrina. Despite the significant impact on mothers, maternal depression trajectories were not associated with differences in children's distress symptoms.
Research by Georgia State University sociologists found that men sharing child-care duties lead to better relationships and sex lives, while women shouldering most responsibilities result in lower quality relationships. Couples with egalitarian arrangements reported equal levels of satisfaction with their sex lives.
The Georgia State School of Public Health will conduct research on smoking prevalence and attitudes towards second-hand smoke in Fulton County. The project aims to inform efforts aimed at improving the environment around tobacco use and creating more smoke-free spaces.
Researchers at Georgia State University developed a vaccine containing virus-like nanoparticles that induces long-term protection against RSV. The study found that mice vaccinated with these particles showed no severe pulmonary disease and lower levels of inflammatory markers after infection.
A new study by Georgia State University researchers found that state regulations significantly influence when patients receive cancer diagnoses, particularly among people under 65. The study suggests that where people live is a strong predictor of whether they will receive potentially life-saving cancer screenings.
A researcher at Georgia State University has received a grant to study an eye disease that causes vision loss and blindness in HIV-immunosuppressed patients. The goal is to understand the mechanisms of HCMV retinitis and find ways to prevent or treat the debilitating disease.
A large-scale study has identified structural brain abnormalities in patients with schizophrenia, including smaller hippocampus and amygdala volumes and larger ventricle volumes. The findings provide new insights into the condition's development and potential treatment responses.
The project aims to improve food environments and increase physical activity in southwest Atlanta's target neighborhoods. Over three years, it will work to increase healthy food access for at least 75% of the communities.
Dr. Jian-Dong Li is developing novel anti-inflammatory therapeutics against middle-ear infections, a major childhood bacterial infection causing conductive hearing loss. The goal is to suppress overactive inflammation and improve middle-ear hearing function.
A national study found that over half of substance abuse counselors personally experienced workplace violence, leading to concerns for personal safety, impaired job performance, and decreased quality of care. Organizations responded with increased training and security measures.
Researchers at Georgia State University found a doubling of establishments permitting smoking in designated dining areas and outdoor spaces. The percentage of restaurants and bars allowing smoking nearly doubled from 9.1% to 17.6% between 2006 and 2012.
A study by Georgia State researchers has found that protected areas in Brazil, Costa Rica, and others can prevent carbon dioxide release worth $5 billion. The research integrates modeling and empirical measures to improve conservation planning by studying policy impacts on ecosystem services.
A team of scientists has discovered a new enzyme that plays a critical role in the biosynthesis of vitamin A in plants and its unexpected dependence on heme iron. The findings could help increase the levels of provitamin A carotenoids in food crops, reducing global vitamin A deficiency.
Researchers at Georgia State University found that chimpanzees can adjust their behavior based on confidence in their responses to memory tests. The study suggests that chimpanzees share with humans the capacity for metacognitive monitoring, which reflects a form of cognitive control underlying intelligent decision-making across species.
A new study at Georgia State University links delay of gratification in chimpanzees to white matter connectivity between the caudate and dorsal prefrontal cortex. The researchers found that higher connectivity was associated with better delay of gratification performance, a crucial ability for mental health.
Researchers at Georgia State University found that an existing anti-stroke drug, Vinpocetine, is effective in suppressing mucus overproduction and improving bacterial clearance in animal studies. The study could lead to a novel, non-antibiotic treatment for otitis media, potentially reducing hearing loss and enhancing host defense.
A new class of protein-based contrast agents (PRCAs) has been developed to detect liver cancer at an early stage, providing robust results. The agent, ProCA32, allows for imaging of liver tumors measuring less than 0.25 millimeters with improved sensitivity and accuracy compared to existing methods.
Researchers found that toddlers, especially those with siblings, understand the behavioral effects of different types of sound on others. Children made loud noises to wake up the doll and quieter noises to let it sleep, showing they understood how their sounds influenced social interactions.
Researchers found chimpanzees could plan route in computer mazes, while monkey species struggled with harder mazes requiring inhibition and anticipation. Human children also performed well, but showed variability in abilities across ages.
Researchers found that combining mental practice with physical therapy significantly improves sensation and motor function scores in stroke survivors. The treatment helps regain motor behaviors by recruiting new neurons and compensating for damaged brain cells.
Brown fat tissue communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity. The study found that when brown fat tissue was activated with a drug, it talked back to the brain by activating sensory nerves.
A new study found that medication for type II diabetes activates sensors on brain cells, increasing hunger and leading to weight gain. Researchers at Georgia State University discovered the role of peroxisome proliferator-activated receptor Upsih (PPAR&Upsih) sensors in controlling eating behavior.
Researchers discover roflumilast's mechanism of tolerance in severe COPD patients, highlighting potential for new therapeutics to improve efficacy. The study identifies key protein PKA-Cβ as a target for reducing unwanted PDE4B2 production.
A recent study by researchers at Georgia State University suggests that storing Ebola-infected sewage for a week or longer may not be sufficient to inactivate the virus, especially at lower ambient temperatures. The study used bacteriophage Φ6 as a stand-in for Ebola and found that holding times may need to be longer in such cases.
Emulsifiers found in processed foods can alter the gut microbiota composition and induce intestinal inflammation, promoting the development of inflammatory bowel disease and metabolic syndrome. The study suggests that avoiding excess food consumption is crucial, as low-grade inflammation from an altered microbiota can lead to overeating.
The Georgia Health Policy Center has received a $2.7 million grant from the CDC to study transfusion-related complications in patients with hemoglobin disorders, aiming to improve their outcomes. Researchers will explore approaches for reducing complications, developing data-driven solutions, and empowering patients and providers.
Researchers identified five genetic variants influencing brain structure size, particularly in regions associated with memory and movement. The study, the largest analysis of brain structure and genetics, aims to understand the causes of variation in human brain development and disease predisposition.
Glucocorticoids suppress inflammation by targeting nuclear factor-κB and upregulating IRAK-M, a key negative regulator of inflammatory pathways. The discovery provides new insights into the mechanism of glucocorticoid action and could lead to the development of new therapeutic strategies for controlling overactive inflammation.
The Georgia State University School of Public Health has received a five-year contract to coordinate Youth Mental Health First Aid Training (YMHFA) and other professional development efforts. The program will teach citizens to support adolescents experiencing behavioral health or addiction challenges.
A team of researchers at Georgia State University has made groundbreaking discoveries in the tryptophan kynurenine pathway, a metabolic pathway linked to psychiatric and neurodegenerative disorders. The study reveals an unexpected enzymatic activity that could lead to new drug design for these diseases.
Georgia State University will partner with Chinese health officials to expand tobacco control efforts in major cities, protecting non-smokers from second-hand smoke and encouraging smokers to quit. The project aims to curb smoking and increase quit rates in China, where the country produces more tobacco than any other nation.
The Paleolithic diet is unlikely to be a single entity due to variations in early human diets across time and space. Early humans were likely dietary 'jacks-of-all-trades' with diverse eating habits influenced by environments and lifestyle.
A new study by Georgia State University and CDC finds that US taxpayers spend $45 billion on Medicare, $39.9 billion on Medicaid, and $23.8 billion on other government-sponsored insurance programs each year due to smoking-related diseases. Smoking accounts for 8.7% of annual healthcare spending in the US.
Researchers at Georgia State University and Cornell University found that promoting healthy gut microbiota can treat or prevent metabolic syndrome. The study used an improved technical approach to show that altered bacterial populations promote low-grade inflammation and metabolic syndrome.
A Georgia State University research team has developed a novel method to prevent and cure rotavirus infection by activating the innate immune system with the bacterial protein flagellin. This approach triggered an immune response that prevented the virus from entering cells and removed existing infections.
A five-year, $750,000 grant will be used to prepare rehabilitation counselors at Georgia State University to work with people with mental illness and psychiatric disabilities. The program aims to address diverse populations and provide innovative training and practice-related needs for the profession of rehabilitation counseling.
Researchers at Georgia State University used the Granger causality test to analyze brain signals and locate seizure sources, improving surgical outcomes for patients. The study found that the test can detect seizures up to 10 seconds earlier than previous methods, leading to a higher cure rate.
Researchers at Georgia State University's Center for High Angular Resolution Astronomy observed a nova's early fireball stage and revealed its complex expansion. The study, published in Nature, used the CHARA Array to create high-resolution images of the explosion, shedding new light on the structure of ejected material.