Researchers at HKUST have developed a novel strategy to create solid-state electrolytes with high performance, achieving exceptional ionic conductivity and lithium-ion transport capability. The new electrolyte enabled the fabrication of a full cell demonstrating an initial discharge capacity of 141.5 mAh g−1 at room temperature.
A research team at HKUST has identified new host factors that facilitate SARS-CoV-2 entry into host cells. The study reveals that these factors, including SH3BP4 and ADAM9, promote viral internalization via the endocytic pathway and may enhance the entry of the SARS-CoV-2 Delta variant.
A research team led by HKUST developed a liquid metal-based electronic logic device that mimics the intelligent prey-capture mechanism of Venus flytraps. The device exhibits memory and counting properties, allowing it to respond intelligently to stimulus sequences without additional components.
A new detection method for high-frequency gravitational waves (HFGWs) has been proposed by HKUST researchers. This approach leverages the physical effect of GWs within magnetic fields and can be detected using existing telescopes, opening up new possibilities for studying the early universe and violent cosmic events.
A recent HKUST study reveals that people's scientific and religious beliefs are primarily formed through testimony from experts or their community, rather than direct experience. This understanding can help promote greater acceptance of scientific facts, especially in emerging topics like climate change.
Researchers at HKUST have developed a sustainable and controllable strategy to manipulate interfacial heat transfer, enhancing the performance of eco-friendly cooling in various applications. By leveraging a water adsorption process, they increased thermal energy transfer across interfaces by up to 7.1 times.
Researchers at HKUST discovered that phase separation enables controlled movement of synaptic vesicles between different regions of the cell. They identified two key proteins, Piccolo and TFG, involved in this process.
Carboxysomes, tiny compartments in certain bacteria and algae, convert carbon dioxide into organic compounds. HKUST researchers have discovered their assembly mechanism, which could help redesign and repurpose them to boost photosynthesis in plants. The breakthrough aims to improve crop yields and mitigate global warming.
A research team has developed a mechanism for electrical 180° switching of the Néel vector in antiferromagnetic materials, featuring C-paired spin-valley locking. The study demonstrates the material's capability to manipulate the Néel vector, enabling the manufacturing of ultrafast memory devices with high efficiency and reproducibility.
Researchers at HKUST developed biomimetic olfactory chips with up to 10,000 individually addressable gas sensors per chip, achieving exceptional sensitivity and distinguishability for mixed gases. These chips have potential applications in industries, security patrols, and rescue operations, and may one day be used to detect diseases b...
Researchers have developed a blood test that accurately detects Alzheimer's disease (AD) and mild cognitive impairment (MCI), with high accuracy rates of over 96% and 87%, respectively. The test measures multiple biomarkers and is applicable across ethnic populations, offering a global solution for diagnosis and management.
Researchers at HKUST have developed a novel selective direct epitaxy method, called lateral aspect ratio trapping (LART), to efficiently integrate III-V compound semiconductor devices with silicon. This breakthrough enables high-speed, low-cost connections that can handle massive amounts of data.
Researchers created an AI-enabled model to help mitigate global ammonia emissions from agriculture. By optimizing fertilizer management, the model can effectively reduce emissions by up to 38%, with Asia having the highest potential for reduction.
Researchers from HKUST developed a sensor array design inspired by the human auditory system to optimize application in fields like robotics, aviation, healthcare, and industrial machinery. The design addresses traditional challenges such as complex wiring, limited reconfigurability, and low damage resistance.
Researchers at HKUST have developed an optical plasmonic tweezer-controlled SERS platform to detect pH-dependent amylin species, revealing the secrets behind amyloid aggregation mechanisms. The platform enables efficient and high-throughput single-molecule characterization of various amylin species.
Researchers at Hong Kong University of Science and Technology have mapped the high-resolution structure of a little-known cyanophage virus, shedding light on its role in controlling marine biogeochemical cycles. The study provides new insights into how viral proteins interact to make the virus stable and infect cells.
A HKUST research team identified TMED10 as a protein that facilitates the secretion of insulin-like growth factor 2 (IGF2), which is crucial for muscle stem cell differentiation. The study provides valuable insights into the mechanisms underlying IGF2's functions and suggests potential therapeutic strategies to modulate its signaling.
A research team at HKUST has identified VCAM1, a cell surface protein on immune cells of the brain, as a therapeutic target for Alzheimer's disease. They found that stimulating the VCAM1-APOE pathway reduces AD pathology in a mouse model.
The HKUST research team has developed a microprinter that can print piezoelectric films 100 times faster, enhancing mass production costs and control of structures and feature sizes. The printer boasts the fastest speed in existing techniques for piezoelectric micrometer-thick films.
The study found that satellite cells possess an inherent capacity to sense and respond to regenerative cues independent of external signals from non-myogenic cells. Macrophages played a crucial role in regulating MuSC proliferation and differentiation, but their reduction led to impaired cell division and increased fibrosis.
A research team led by HKUST developed an AI-powered model to predict glioma patients' prognosis and identify early predictors of tumor evolution under therapy. The model, CELLO2, uses genomic and transcriptomic data from 544 glioma patients to accurately predict treatment-induced hypermutation and grade progression.
Researchers at HKUST have found that the stem cell niche uses gap junctions to transport cAMP into stem cell progeny, controlling their differentiation. This discovery is significant for developing stem cell therapies to treat diseases such as Parkinson's and Alzheimer's.
A HKUST research team has developed a novel technique to self-assemble a thin layer of amino acids with ordered orientation, demonstrating high piezoelectric strength. The technique enables the production of biocompatible and biodegradable medical microdevices, such as pacemakers and implantable biosensors.
A joint study reveals significant alterations in gene regulation within the placenta due to COVID-19 infection, potentially leading to abnormal blood vessel formation and fetal growth restriction. The research also identifies dysregulation of angiogenesis genes and downregulation of pregnancy-specific glycoprotein genes.
A Hong Kong University of Science and Technology team developed a technique to analyze fish DNA, revealing the complex relationships among marine species and how global warming affects them. The study found that water temperature can have both positive and negative effects on fish interactions.
A research team from HKUST identified CPEB4, an mRNA-binding protein, as a key player in maintaining mitochondrial metabolism and energy production. Restoring CPEB4 expression in aged muscle stem cells improved energy production and protected against cellular senescence.
Researchers at HKUST created an AI-based model that uses genetic data to forecast AD risk, outperforming existing models. The deep learning model accurately classifies patients and stratifies individuals into distinct risk groups, enabling early diagnosis and intervention.
The discovery of the noncanonical cleavage mechanism solves a two-decade-long mystery in molecular biology regarding the cleavage of numerous pri-miRNAs in animals. The study reveals previously unrecognized DROSHA recognition sites, which are critical for noncanonical cleavage and can also function in the canonical mechanism.
Researchers at Hong Kong University of Science and Technology propose the existence of pre-solid-solid transition, a surface layer on crystals that facilitates phase transitions. The newly formed layer has been confirmed through experiment and computer simulation, with promising applications in material science.
A study by HKUST researchers found that children and adults preferentially view naturals as more competent and friendly than hard workers, a preference that endures into adulthood. The naturalness bias impacts children's interactions with peers perceived as talented or hardworking.
Researchers at HKUST developed a novel technology to simultaneously sequence genomic DNA and RNA in single cells from frozen tissues, enabling the discovery of rare brain tumor cell subpopulations. This breakthrough facilitates cancer research for complex tumors and opens new directions for drug target discovery.
Researchers at HKUST mapped out the fundamental mechanisms of C.elegans Microprocessor (cMP), revealing its distinctive molecular mechanism. The study suggests that cMP's two subunits, cDrosha and Pasha, determine cleavage sites using distinct methods, differing from human MP in multiple aspects.
An international research team investigated a surprising coral bleaching episode in Moorea, finding that anti-cyclonic eddies elevated sea levels and concentrated hot water, leading to an underwater marine heatwave. Long-term data revealed the importance of considering environmental dynamics across ocean depths to predict coral bleaching.
Researchers have identified an intrinsic immune mechanism that promotes axon regeneration in peripheral nerves after injury. Deleting PTPN2 and combining it with type II interferon IFNγ accelerates axon regrowth, a potential breakthrough for treating spinal cord injuries.
Researchers at HKUST have developed a novel integration scheme using lateral aspect ratio trapping (LART) to efficiently couple III-V lasers and photodetectors with silicon on silicon photonics platform. This breakthrough enables the integration of energy-efficient photonics with cost-effective electronics.
Researchers at HKUST designed an innovative iron-based cathode material to achieve record performance for protonic ceramic fuel cells. The new material, Ba0.875Fe0.875Zr0.125O3-δ, has exceptional electrochemical activity and excellent operational stability.
Researchers at Hong Kong University of Science and Technology have discovered that CO2 in the deep Earth's dissolution in water may be more active than previously thought, influencing global climate over geologic time. Confining CO2 and water in suitable nanoporous minerals enhances underground carbon storage efficiency.
Researchers have identified changes in chromatin accessibility that occur in aging muscle stem cells, which may be reversible. By understanding these changes, scientists can develop new approaches to prevent or reverse cellular aging.
A data-intelligent model reveals that prioritizing vaccine access for the most disadvantaged communities can improve health benefits for all. The research team also argues for increased funding to combat vaccine hesitancy among these populations.
A new study has suggested that recommended VACV-based vaccines will mount a robust immune response against the 2022 monkeypox virus. The research found that the genetic mutations observed in MPXV-2022 may not significantly affect vaccine-induced immunity.
Researchers have identified a blood protein, soluble ST2 (sST2), that plays a key role in disrupting Aβ clearance by microglia. Lowering sST2 levels may offer a simpler and safer approach to treating Alzheimer's disease, particularly for high-risk groups such as female APOE4 carriers.
A new electrode design enables the rechargeability of alkaline zinc batteries, reducing waste and promoting sustainability. The nanoporous zinc metal electrode stabilizes the electrochemical transition between zinc and zinc oxide, allowing for over 80 hours of stable charging.
A joint study by HKUST and HKUMed researchers has identified a broadly neutralizing antibody, ZCB11, that protects Syrian hamsters against all SARS-CoV-2 Omicron variants. The antibody demonstrates potent antiviral activities and can protect lung infection under both prophylactic and therapeutic conditions.
Researchers at HKUST developed a new hydrogen fuel cell with 97% platinum catalytic activity after 100,000 cycles, outperforming current catalysts. The new fuel cell uses a hybrid catalyst with three active sites, accelerating reaction rates and achieving higher power delivery.
A research team led by Prof. Gan Jianping found a three-layered structure in the SCS rotating circulation with 'hotspots' of intensified currents along steep continental slopes. This discovery clarifies previous misunderstandings of water mass motion and demonstrates the first-ever 3D simulation and visualization system for ocean circu...
A HKUST research team developed a microscope combining 3PM with adaptive optics, achieving high-resolution imaging of neuronal structures in mouse cortices up to 750µm below the skull. This technology holds great potential to advance in-vivo imaging techniques and facilitate study of living brain.
A comprehensive study by Hong Kong University of Science and Technology revealed that anthropogenic low-volatility organic vapors play a critical role in forming secondary organic aerosols (SOA) and haze pollution in urban environments. The research found that oxidation of VOCs dominates OOMs formation, with nitrogen oxides significant...
A novel SURF4-to-proteoglycan relay mechanism regulates the secretion of sonic hedgehog (Shh), a key signaling molecule in cancer progression. The study offers new insights into inhibiting Shh secretion and shutting down the Hh signaling pathway to hinder cancer progression.
Researchers from HKUST have identified secondary RNA elements that control DICER's cleavage activity, improving miRNA expression and shRNA design for effective gene silencing. The study provides a foundation for designing accurate and efficient short-hairpin RNAs.
A research team at HKUST has developed a long-term in vivo imaging technique to study spinal cord injury, allowing for repeated and stable imaging without triggering inflammation. The breakthrough enables researchers to track microglia and understand their interaction with degenerating and regenerating axons.