The new guidelines recommend dietary approaches such as eating kiwis, rye bread, and drinking high-mineral water to alleviate chronic constipation. The guidelines also suggest taking psyllium fibre supplements, certain probiotic strains, and magnesium oxide supplements to improve symptoms.
A study published in Annals of Neurology reveals a genetic connection between errors in the EPG5 gene, which causes Vici syndrome, and Parkinson's disease. Researchers found that individuals with rare errors in EPG5 were more likely to develop Parkinson's disease and dementia.
A new global standard has been established to harmonize outcomes measurement in dengue treatment trials, addressing a longstanding discrepancy that limits the comparison of evidence. The initiative aims to accelerate the development of treatments for dengue fever and improve clinical guidelines, with input from experts worldwide.
Despite no decrease in usage, Wikipedia faces challenges from AI data scrapers and Large Language Models. The platform is struggling to allocate resources due to the influx of AI training data, threatening its current structure.
Researchers at King's College London have developed a genetic test that can predict which women with abnormal breast cells are most likely to develop invasive breast cancer. The test uses a genetic risk score to estimate a person's inherited likelihood of developing the disease, allowing for more personalized treatment options.
A King's College London study reveals how income inequality is associated with altered connections and reduced surface area in the brains of children, leading to poorer mental health outcomes. The research suggests that implementing policies to reduce societal inequality could promote healthy neurodevelopment.
Deaths due to ketamine use increased twenty-fold between 1999 and 2024, with polydrug settings dominating cases. The study highlights a shift towards older, disadvantaged individuals as primary users, raising questions about single-substance policies.
A low-cost drug, heparin, has been shown to be effective in treating seriously ill COVID-19 patients by reducing the risk of ventilation and death. The study found that inhaling heparin targeted directly to the lungs improved breathing and oxygen levels in patients.
Researchers found a significant link between severe pregnancy sickness (hyperemesis gravidarum) and an increased risk of mental health conditions. Women with HG experience anxiety, depression, and postpartum depression, highlighting the need for integrated care across physical and mental health.
A study published in the Journal of Periodontology suggests that following a Mediterranean-style diet rich in plant-based foods like legumes and fruits may lower gum disease severity. The research found that patients with higher intake of red meat experienced more severe gum disease and inflammation.
Scientists at King's College London discover mathematical equations that turn random events into clocks, potentially understanding cell timekeeping and detecting quantum effects. The study also aims to shed light on the nature of time itself, including its directionality and quantization.
Researchers at King's College London have discovered that cells use electricity to selectively target and eliminate the weakest neighbours, helping to maintain a balanced and healthy protective layer. This process, known as extrusion, is crucial for balancing cell division and death, and disrupting it can lead to disease.
A new UK review reveals that 89-97% of autistic adults aged 40+ are undiagnosed, leading to a higher risk of age-related health problems. Middle-aged and older autistic adults face significant challenges in employment, relationships, and wellbeing.
Research from King's College London and University of Bath found that people who self-medicate with cannabis for physical or mental discomfort are more likely to develop paranoia and anxiety. The study also discovered a link between childhood trauma and increased paranoia scores, which is exacerbated by cannabis use.
A new clinical trial found that genetic testing of IVF-created embryos can improve pregnancy and live birth rates for women aged 35-42, reducing the time to conception and emotional toll of failed cycles. The study showed a 20% increase in cumulative live births with 72% success rate compared to 52% without PGT-A
A new study suggests that space-based solar power could reduce Europe's need for land-based renewable energy by up to 80%, cutting energy storage needs by over two-thirds. The technology also saves money by reducing the cost of the entire power system, with estimated annual savings of €35.9 billion.
A recent study published in Alzheimer's & Dementia found that women with Alzheimer's disease have a notable loss of unsaturated fats, such as omega-3 fatty acids, in their blood compared to healthy women. This suggests that lipids containing omega-3 fatty acids may play a crucial role in the risk for Alzheimer's between the sexes.
Researchers at King's College London found that AI chatbots can be exploited to reveal up to 12.5 times more personal information from users. The study used three types of malicious AIs to encourage disclosure of private info, with reciprocal strategies proving the most effective.
Researchers at King's College London discovered that keratin can repair tooth enamel and stop early stages of decay. Keratin forms a protective coating that mimics the structure and function of natural enamel.
Researchers found that a small, AI-powered implantable EEG can track seizures in the home environment with high accuracy. The device captured over 72,000 hours of brainwave data and detected 754 seizures, outperforming participants' self-reported records.
Scientists at King's College London have developed an 'interactional fingerprinting' method to characterise graphene oxide (GO) cheaper and quicker than ever before. This new approach allows for a qualitative snapshot of individual samples by mimicking humans' sense of taste and smell, enabling researchers to quickly quality control th...
A groundbreaking cancer drug, KCL-HO-1i, has shown promise in making chemotherapy-resistant cancers more responsive to therapy by targeting a key defence mechanism used by tumours. In preclinical models, the drug has already demonstrated effectiveness in laboratory tests using mouse models of breast cancer.
A study by King's College London found that UK adults consume a median of eight different plants daily, with varying levels of diversity associated with better health outcomes. Higher plant food diversity is linked to improved cholesterol levels, blood sugar markers, and nutrient intake.
Researchers at King's College London discovered that ketamine's antidepressant effects involve the brain's opioid system, which works together with glutamatergic systems to produce rapid treatment effects. The study also identified a sex-related effect, where males with depression showed a more pronounced response to naltrexone.
A study published in Addiction found that nearly half of drug-caused deaths among healthcare workers involved hospital-only drugs. Opioids were the most frequently involved substance, followed by benzodiazepines, and anaesthetists were disproportionately represented in these deaths.
The study found that alopecia stigma affects over 80% of patients with anxiety or depression, while those with more positive perceptions have lower anxiety symptoms. The researchers hope to assess patients' illness perceptions and stigma in routine check-ups to provide targeted support.
A third of women who died during or in the year after pregnancy were known to Children's Social Care, with most deaths due to suicide, psychiatric causes, and homicide. The study highlights the need for coordinated care and support for mothers with social care involvement.
A new study by King's College London and University of Sussex found that content moderators engage in five main practices to manage distressing material, including emotion management and empathy. The research calls for regulators and platform providers to reduce the toll of this highly skilled emotional work.
Researchers at King's College London used cryo-electron microscopy to study the flagellum in unprecedented detail, revealing its architecture and identifying potential drug targets. This breakthrough could lead to the development of new treatments for bacterial infections without driving resistance.
The UK's healthcare professionals are now equipped with evidence-based guidance on managing patients taking private weight loss medications. The ten tips emphasize the importance of prioritizing patient safety and providing wrap-around care like dietary advice and psychological support.
A community-based mentoring scheme in Sierra Leone has been found to save lives and help girls return to education, doubling survival rates. The pilot trial reduced maternal and perinatal deaths by almost half, with one baby's life saved for every 18 mentored girls.
The UK's first AI for Science Master's programme was launched by King's College London, focusing on interdisciplinary research and education. The programme aims to create a generation of AI-minds ready to tackle scientific challenges, with applications in areas such as biomedicine, chemistry, and materials science.
Researchers identified genetic factors linked to environmental sensitivity in identical twins, influencing ADHD symptoms, autistic traits, anxiety and depression symptoms, psychotic experiences, and neuroticism. The study highlights the importance of gene-environment interactions in shaping mental health.
A study by King's College London found that specific changes in the microbiome are associated with cognitive decline in Parkinson's disease. The research suggests that oral-gut translocation may play an active role in worsening symptoms.
New research reveals distinct effects of APOE isoforms on human microglia function, with APOE4 increasing inflammation and APOE2 promoting proliferation and migration. The study suggests targeted interventions based on APOE genotypes may be crucial in disease progression.
A promising new anticancer medicine could be made from a mixture of potentially dangerous isomers, which have the same elemental make-up but different structures. This challenges over 60 years of established scientific wisdom and literature, posing major concerns about its use in human subjects.
Researchers created over 3,800 anatomically accurate digital hearts to investigate how age, sex, and lifestyle affect heart disease. They found that age and obesity cause changes in the heart's electrical properties, which could explain why these factors are linked to a higher risk of heart disease.
A study by King's College London found that post-stroke depression can have serious long-term effects on stroke survivors, lasting up to 10 years. Researchers tracked over 2,500 stroke survivors and found that those with depression were nearly three times more likely to develop long-term physical disability.
A study by King's College London reveals how surveillance technologies in smart homes exacerbate power imbalances between domestic workers and employers, undermining their rights and increasing vulnerability. The constant monitoring of these employees can lead to mental wellbeing issues and a lack of trust in the workplace.
A new study reveals that shift workers' disrupted circadian rhythms can lead to muscle decline and accelerated ageing. Muscle cells contain their own internal clocks that regulate protein turnover, modulating muscle growth and function.
Researchers at King's College London discovered that the amount and characteristics of bomb residue on a person's hands depend on the individual, not just the type of explosive. The study provides context for forensic experts to better interpret residue in cases involving energetic materials.
New research published in the New England Journal of Medicine shows that semaglutide effectively treats liver disease in two-thirds of patients with MASH. The substance has been found to halt and even reverse the disease, reducing steatohepatitis and improving liver fibrosis.
A highly sensitive bone marrow test has shown to double survival rates for patients with AML mutations in NPM1 and FLT3 genes, allowing for early detection of potential relapse. This trial indicates that regular molecular testing can improve long-term survival rates by restarting treatment earlier.
The study shows that two-thirds of adults with severe peanut allergy can tolerate five peanuts without reacting after undergoing oral immunotherapy. The treatment improves quality of life and reduces fear of food, allowing participants to enjoy everyday situations without anxiety.
A mysterious parasite is devastating fish farms globally, causing £50 million in losses annually. Researchers have discovered a new gene regulation process that could lead to the development of gene-based vaccines.
Researchers at King's College London and Harvard University develop a detector that can identify axions, leading potential candidates for dark matter. The Axion Quasiparticle (AQ) technology has the potential to discover dark matter in five years with further development.
Researchers have identified new candidate genes that could be responsible for congenital deafness, a condition affecting around one in 1,000 babies born in the UK. The study suggests that understanding these gene mutations may hold the key to devising effective treatments.
Researchers have shed light on how a new type of antibody treatment works against ovarian cancer by reactivating patients' immune cells. The study shows that MOv18 IgE reverses the suppression of immune cells and induces them to kill cancer cells, providing new insights into this therapy.
Elite female athletes in the UK shared their experiences with pregnancy, citing a lack of guidance on nutrition and training that complements athletic ambition. They also expressed concerns about the impact of training on pregnancy and child development, as well as limited support networks within the sporting community.
A new study shows that AI-assisted 20-week pregnancy scans are accurate and reliable, taking only over 40% less time than standard scans. This allows sonographers to focus on other aspects of the scan, such as communicating with parents.