LSU Health New Orleans has been awarded a $10 million grant to support research on viruses that cause cancer. The funding will be used to study the molecular details of virus-host interactions and develop new diagnostic and therapeutic approaches.
Researchers at LSU Health New Orleans will investigate the potential efficacy of Exscien1-III, a patented three-part fusion protein designed to repair DNA damage and improve cardiovascular disease outcomes. The goal is to move the promising new drug toward human clinical trials.
The LSU Health New Orleans School of Public Health will receive a $15 million grant over five years to support its cancer education, early detection, and control programs. The funding will help improve cancer screening rates and reduce disparities in cancer care across the state.
A study by LSUHealthNO found that 86% of high-risk heterosexuals in New Orleans would use a home-based test kit, leading to increased HIV testing and treatment rates. The study suggests that this self-administered alternative may reach individuals who are under-recognized as at risk, promoting timely treatment.
Research led by Dr. Lauri Byerley found that walnuts increase beneficial bacteria in the gut, promoting a diverse microbiota. This shift in gut bacteria has been associated with better health outcomes, including reduced risk of cardiovascular disease and inflammatory bowel disease.
Research by LSU Health New Orleans scientists may lead to a treatment for long-term sensory problems in cardiac arrest survivors. The study used rodent models and computer modeling to show that cardiac arrest damages the cerebral cortex, leading to decreased sensory responsiveness.
The project aims to strengthen resilience in under-resourced communities by testing two approaches: providing technical resources or supporting community planning. The research will also investigate mobile phone-based applications to enhance skills to cope with stress and develop policy recommendations.
Researchers at LSU Health New Orleans found that docosahexaenoic acid (DHA) and its bioactive derivative NPD1 can reduce stroke damage and promote cell survival in the brain. DHA is essential for maintaining cellular homeostasis, which is disrupted in diseases such as Alzheimer's and Parkinson's.
A two-year-old girl who suffered cardiac arrest after a cold water drowning accident showed significant neurological improvement with normobaric oxygen and hyperbaric oxygen therapy. After 39 sessions, she exhibited near-normal motor function, speech level greater than pre-drowning, and normal cognition.
Researchers at LSU Health Sciences Center have discovered a new class of biochemical triggers called elovanoids, which are derived from omega-3 fatty acids. These molecules play a significant role in protecting retinal pigment epithelial and photoreceptor cells from damage.
The research team will test a combination of new technologies that release antibacterial agents in response to acid presence, promising longer service life and improved dental applications. The novel materials aim to inhibit oral biofilm formation and have excellent physical and mechanical properties.
Researchers found that NDP1, a signaling molecule made from DHA, triggers the production of a protective protein against toxic free radicals and injury in the brain and retina. The discovery may contribute to possible therapeutic interventions for retinal degenerations and ischemic stroke.
Researchers found that using techniques that minimize disruption to the lower breast suspensory ligaments improves breast reduction outcomes. The study suggests that preserving these ligaments reduces pseudoptosis, a common long-term complication of breast reduction surgery.
A new tyrannosaur species, Daspletosaurus horneri, has been discovered with an unusual mode of evolution called anagenesis. The research reveals a complex sensory web derived from the trigeminal nerve, similar to humans, and a lipless mask of large scales covering its face.
The LSU Health New Orleans research enterprise will receive a $499,640 NSF grant to upgrade its networking infrastructure and create a Science DMZ. The project aims to facilitate large data exchange, remote collaboration, and leadership in multiple science disciplines.
A new study by LSU Health New Orleans School of Public Health shows that parents' concerns about their neighborhood restrict their children's outdoor play. Parents who do not trust their neighbors or feel they have no control over neighborhood problems are more likely to limit their child's physical activity.
A study integrating field and laboratory experiments with computer simulations found that perception plays a key role in the evolution of counterintuitive traits. Proportional perception limits the evolution of traits by making it difficult to perceive changes in large stimuli.
The Zika virus poses a threat beyond summer months, as Aedes species mosquitoes can survive winter and transmit the virus through their eggs. Experts emphasize the importance of year-round protection measures, including physical barriers and insect repellents.
Researchers at LSU Health New Orleans report a complete response in a patient with long history of melanoma after treatment with a combination of an interferon and melanoma vaccine. The FDA has approved a first-of-its-kind therapy, talimogene laherparepvec, which shows a 10.8% complete response rate.
A novel diagnostic biomarker panel can identify necrotizing enterocolitis in premature infants with high accuracy. The test, developed by LSU Health New Orleans researchers, has the potential to improve disease management and outcomes for thousands of preterm babies each year.
A team of physicians at LSU Health New Orleans has developed a novel technique to identify hidden sources of gastrointestinal bleeding. The method, which combines endoscopy with the administration of antiplatelet or anticoagulant agents, was found to be safe and effective in identifying the source of bleeding in 56% of patients.
The grant aims to create partnerships in disaster-prone regions to enhance national capacity for children's and families' post-disaster response. It adapts the National Child Traumatic Stress Network model, including a digital application for information sharing after disasters.
A study by LSU Health New Orleans found that people with cervical cancer history consumed significantly more sugar-sweetened beverages, while younger, male, black individuals with high sugar intake were also at higher risk. The researchers recommend targeting lower socio-economic status and young males in intervention programs to reduc...
A $5,000 grant will support a school-wide program to educate patients about self-oral cancer screening. The program, led by Dr. Kitrina Cordell, aims to improve early detection and survival rates for oral cancers.
A national team of orthopaedic surgeons identified risk factors contributing to fracture nonunion in adults, including the severity and location of the fracture, presence of diseases, and medication use. Nonunion rates varied by bone type, with scaphoid and tibia/fibula showing the highest rates.
Researchers have reported a new neurological complication of Zika virus infection, specifically sensory polyneuropathy, in a Honduran patient. The study highlights the potential for Zika virus to cause acute infectious sensory polyneuropathy, which began during the acute infectious phase.
A team of researchers developed neuroprotective compounds that prevented seizures and damaged dendritic spines in mice with experimental epilepsy. The study suggests the process of epilepsy development has been arrested up to 100 days post-treatment, offering a potential new approach to disease-modifying treatments.
Dr. Jayne Weiss, an LSU Health New Orleans ophthalmologist, recommends using UV protection not just outdoors but also inside cars to prevent cataracts and skin cancer. She cites studies showing a 93% reduction in cell death when UV exposure is filtered through UV-absorbing auto glass.
Researchers found that early childhood is a protected period from the negative effects of disadvantaged neighborhoods on health outcomes. The study suggests that increasing intervention during this time could ensure cardio-metabolic health in the future.
A protein critical to brain waste removal, TREM2, is diminished in age-related macular degeneration (AMD) and Alzheimer's disease. The research identified a key reason, microRNA-34a, leading to a new treatment target for both conditions.
The fellowship program will provide LSU Health New Orleans M.D./M.P.H. students with working knowledge of health policy, enabling them to better understand the policy context in which healthcare is practiced. The program aims to bridge gaps between healthcare and public health disciplines.
A retrospective study found that freezing nerves before knee replacement surgery significantly improves patient outcomes, with shorter hospital stays and reduced opioid use. The treatment group had fewer knee symptoms and better local pain control, allowing patients to walk and function well enough to go home sooner.
A team of researchers discovered a protein called Pur-alpha that can protect against toxic degeneration in cells, which may lead to a treatment for ALS. The study suggests that Pur-alpha could serve as a novel therapeutic target for developing a treatment for ALS patients.
Researchers developed a new index identifying concurrent but unrelated diseases among AYA cancer patients, highlighting prevalence of mental illness, obesity, and cardiovascular conditions. The AYA HOPE Comorbidity Index can predict service needs and improve treatment outcomes for young cancer patients.
Researchers at LSU Health New Orleans have identified a protein in the retina crucial for vision, which can be harnessed to prevent and slow down retinal degenerative diseases. The discovery offers new hope for treating blindness and visual impairments.
A seven-year study found that responsive direct cortical stimulation significantly reduced seizures by up to 60% and improved quality of life. The Long-Term Treatment Study showed that 84% of participants experienced some improvement, with 16% being seizure-free for at least three months.
A new study confirms earlier findings that African-American children have significantly higher HbA1c levels than their white counterparts despite similar average blood glucose levels. The study calls for prioritizing efforts to identify and address the sources of ongoing disparities in young patients with type 1 diabetes.
Researchers at LSU Health New Orleans have discovered a psychedelic drug that prevents the development of allergic asthma in mice. The study identified a potent anti-inflammatory mechanism for treating asthma, which could one day be administered via an inhaler or daily pill.
Researchers at LSU Health New Orleans have discovered Neuroprotectin D1, a molecule that protects cells from damage and promotes recovery from stroke. This breakthrough could lead to therapeutic solutions for age-related macular degeneration and ischemic stroke.
Researchers at LSU Health New Orleans have discovered a novel compound that regulates brain electrical activity and reduces aberrant signaling leading to severe generalized seizures. The finding may contribute to the development of effective anti-epileptic therapies.
Researchers at LSU Health New Orleans School of Medicine have discovered a toxic fragment of an Ebola virus protein that can change membrane permeability. The Delta peptide fragment has been shown to block the virus from attaching to already-infected cells, offering potential new insights for treatment and prevention.
A study published in Nature Neuroscience found strong associations between mechanisms related to immune function and changes in gene expression. The research identified shared biological pathways among psychiatric disorders, shedding light on the development of these conditions.
A new study found an effective treatment approach to inhibit latent herpes simplex viruses from reactivating and causing disease. The research used existing drugs, such as tranylcypromine, to block proteins involved in viral replication, reducing symptoms and shedding of the virus.
Intra-abdominal infections caused by Candida albicans and Staphylococcus aureus result in high mortality rates due to synergistic inflammatory responses. Researchers hope to identify targeted treatments to decrease severity and improve survival through their study.
LSU Health New Orleans has been awarded a $2.2 million grant to develop and implement strategic health education campaigns for young breast cancer survivors in the Gulf South region. The initiative aims to empower survivors to advocate for their care and access necessary services, improving quality of life.
A new study using LSU Health New Orleans data found Acadian parishes in Louisiana have the highest colorectal cancer rates among nation's founder populations. The Cajun population, with limited genetic variation, may be linked to the high risk of disease.
Researchers at LSU Health New Orleans have discovered that the protein Chop regulates the activity and accumulation of cells that suppress the immune response against tumors. The study found that removing Chop boosts the effectiveness of treatment, revealing it as a target for developing new immunotherapies to treat cancer.
Researchers identified Maresin-Ls, molecules that promote wound healing and reduce inflammation in patients with diabetes. The study restores reparative functions to diabetic macrophages, enabling better treatment of diabetic wounds.
LSU Health New Orleans will enhance its cancer data on children and young adults by linkages with secondary data sets, providing a more robust research resource. The award aims to better understand why survival rates for adolescents and young adults have not improved over the last two decades.
The LSU Health New Orleans School of Nursing received a $700,000 Advanced Education Nursing Traineeship grant to increase access to advanced nursing education and patient care. The program will provide funding for up to 50 PCFNP students from disadvantaged groups.