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Osaka University


Systemic lupus erythematosus linked to altered gut microbiome

A recent study published in Annals of the Rheumatic Diseases reveals a link between systemic lupus erythematosus and an altered gut microbiome. Researchers at Osaka University identified two species of Streptococcus bacteria significantly increased in SLE patients, which can affect the body's functions by altering plasma metabolites. T...

SourceOsaka University·JournalAnnals of the Rheumatic Diseases·TypeData/statistical analysis·DateOct 27, 2021

Targeting cancer at the nanoscale

Scientists at Osaka University developed a novel system for targeted cancer radiation therapy using gold nanoparticles labeled with astatine-211. The nanoparticles are highly toxic to cancer cells while remaining localized, minimizing damage to healthy tissues.

SourceOsaka University·JournalJournal of Nanobiotechnology·TypeExperimental study·DateOct 19, 2021

Intelligence emerging from random polymer networks

A team of researchers from Osaka University has designed a sulfonated polyaniline network for reservoir computing, achieving 70% accuracy in speech recognition tasks. The device uses an electrochemical approach and has potential applications in the development of artificial intelligence devices.

SourceOsaka University·JournalAdvanced Materials·TypeExperimental study·DateOct 6, 2021

Kirigami cools electronics

Researchers developed kirigami-processed cellulose nanofiber films that dramatically improve cooling functionality, reducing thermal resistance by about one-fifth. These films can be used to create new cooling devices for wearable electronics, addressing bulkiness and inflexibility issues.

SourceOsaka University·JournalNPG Asia Materials·TypeExperimental study·DateSep 23, 2021

Tuning flexible circuits with light

A team of researchers has developed a method to precisely modify electronic properties using ultraviolet light, enabling the creation of flexible circuits that can be used in real-time healthcare monitoring and data processing. This breakthrough technology may lead to the development of ultra-lightweight wearable healthcare devices and...

SourceOsaka University·JournalAdvanced Materials·TypeExperimental study·DateSep 21, 2021

Lasers light up neutron generation for radiography

Researchers from Osaka University have developed a laser-driven neutron source that can generate fast neutrons in short bursts, enabling rapid imaging. The technique was used to detect hazardous substances in batteries and images materials like boron carbide.

SourceOsaka University·JournalApplied Physics Express·TypeImaging analysis·DateSep 15, 2021

X-ray street vision

A team of researchers at Osaka University created a custom dataset to train an AI algorithm to digitally remove unwanted objects from building façade images. The algorithm achieved high accuracy in inpainting occluded regions with digital inpainting.

SourceOsaka University·JournalIEEE Access·TypeImaging analysis·DateSep 6, 2021

Copper and PTFE stick together to support better 5G

Osaka University researchers have created an adhesive-free method to strongly combine copper foil with polytetrafluoroethylene (PTFE), reducing transmission losses in electronic circuits. The heat-assisted plasma treatment technique improves adhesion strength without adding intermediate layers.

SourceOsaka University·TypeExperimental study·DateSep 2, 2021

Ultrafast electronic control of magnetic anisotropy by mid-infrared light

A team of researchers from Osaka University and international partners used intense mid-infrared laser pulses to alter magnetic anisotropy in a weak ferromagnet. They found that electronic excitation, rather than lattice heating, was responsible for the ultrafast change, enabling faster spintronics devices. This breakthrough has signif...

SourceOsaka University·JournalPhysical Review Letters·TypeExperimental study·DateSep 1, 2021

Paint the town

A team of scientists from Osaka University developed a machine learning method for classifying the type of building and its primary façade color using deep learning models applied to street-level images. This work may assist in fostering neighborhood cohesion and support urban renewal by providing tailored street-view datasets.

SourceOsaka University·JournalISPRS International Journal of Geo-Information·DateAug 31, 2021

Taking the pain out of kidney stone analysis

A team of scientists has reported a technique that provides the most detailed picture of kidney stone components yet. The researchers used a novel method to analyze kidney stones, revealing the distribution of three different proteins and their role in crystal growth.

SourceOsaka University·JournalScientific Reports·TypeObservational study·DateAug 26, 2021

Eye in the sky

The team used machine learning technique generative adversarial networks to digitally remove clouds from aerial images, generating accurate datasets of building image masks. This work may help automate computer vision jobs critical to civil engineering, enabling the detection of buildings in areas without labeled training data.

SourceOsaka University·JournalAdvanced Engineering Informatics·TypeComputational simulation/modeling·DateAug 26, 2021

No swimming? Molecule regulating sperm motility discovered

Researchers from Osaka University identified SPATA33 as a key regulator of sperm motility, which will aid in developing fast-acting male contraceptives. The study also clarified the mechanism by which SPATA33 controls sperm motility, shedding light on the cause of male infertility.

SourceOsaka University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateAug 23, 2021

Seeing both the forest and the trees: Trans-scale scope shows big picture of tiny targets

Scientists from Osaka University create optical imaging system that can capture over a million cells in a single image, enabling simultaneous observation of centimeter-scale dynamics with micrometer resolution. This technology, termed 'trans-scale scope,' may accelerate research in fields such as neuroscience, oncology, and immunology.

SourceOsaka University·JournalScientific Reports·TypeImaging analysis·DateAug 20, 2021

Accessing high-spins in an artificial atom

Osaka University researchers demonstrate the readout of spin-polarized multielectron states composed of three or four electrons on a semiconductor quantum dot. This breakthrough may lead to quantum computers utilizing high-spin states, enabling faster and higher-capacity processing.

SourceOsaka University·JournalPhysical Review Letters·TypeExperimental study·DateAug 19, 2021

A winning combination for glycoprotein synthesis

Researchers from Osaka University have demonstrated a rapid and robust chemical method for preparing highly pure glycoproteins. The new synthetic route uses an unprecedented amide bond formation reaction to form a junction between two functional peptides, resulting in a reliable means of synthesizing glycoproteins with little waste of ...

SourceOsaka University·JournalJournal of the American Chemical Society·TypeExperimental study·DateAug 10, 2021

The path(way) less traveled in DNA double-strand break repair

Researchers from Osaka University found that protein phosphatase 1 binds to RIF1 at broken DNA ends, blocking proteins that create single-stranded DNA tails, and promoting the non-homologous end joining repair pathway. This novel mechanism helps protect double-strand breaks from developing a tail, which is what Shieldin binds to.

SourceOsaka University·JournalCell Reports·DateJul 13, 2021

A way to surmount supercooling

Researchers at Osaka University found that silver nanoparticles induce crystallization in clathrate hydrates, a potential application for latent heat storage materials. The study may lead to improved efficiency in solar energy and heat recovery technologies.

SourceOsaka University·JournalCommunications Materials·DateJun 28, 2021

Passing the COVID test in just five minutes

Researchers at Osaka University have created a new, highly sensitive test for the SARS-CoV-2 virus that uses artificial intelligence and nanopore technology. The test platform achieved a sensitivity of 90% and specificity of 96% for SARS-CoV-2 detection in just five minutes using clinical saliva samples.

SourceOsaka University·JournalNature Communications·DateJun 17, 2021

From symmetry to asymmetry: The two sides of life

The study uses innovative imaging techniques to demonstrate the role of symmetric cell nucleus alignment in left-right asymmetric development. Collective nuclear behavior and proper nuclear positioning are found to be responsible for subsequent LR-asymmetric development of the midgut.

SourceOsaka University·JournalDevelopment·DateJun 15, 2021

Activation of carbon-fluorine bonds via cooperation of a photocatalyst and tin

Researchers from Osaka University have successfully developed an organic reaction that selectively converts a specific carbon-fluorine bond in perfluorinated compounds to other functional groups. This breakthrough enables the synthesis of high-value fluorine-containing drugs, addressing a significant challenge in pharmaceutical applica...

SourceOsaka University·JournalJournal of the American Chemical Society·DateJun 2, 2021

Keeping it rolling

Scientists at Osaka University employ machine learning algorithms to assess the remaining useful life of mechanical rolling bearings, which may lead to industrial cost savings and fewer discarded parts. The new method improves prediction accuracy by about 32%.

SourceOsaka University·JournalIEEE Access·DateMay 24, 2021