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The University of Osaka


The secret ingredient is time: The role of timing in brain development

The study reveals that rats have a larger deep layer in their brains due to the prolonged expression of Wnt signaling genes, resulting in extended deep layer neuron production. This finding suggests that 'heterochrony' in neurogenesis is responsible for the interspecific diversity in the neuronal composition of the mammalian cortex.

SourceThe University of Osaka·JournalThe EMBO Journal·TypeExperimental study·DateMay 25, 2026

Exploiting interfacial ionic mobility to make heat-moldable nanoparticle aggregates

Researchers at The University of Osaka developed a strategy to make nanoparticle aggregates thermoplastic by introducing ions at interfaces. This allows for the creation of high-strength and low-expansion materials suitable for various applications. The study paves the way for diverse systems, including graphene oxide and cellulose nan...

SourceThe University of Osaka·JournalScience Advances·TypeExperimental study·DateMay 15, 2026

Flu signals in wastewater offer an early warning for community outbreaks

A University of Osaka-led team developed a wastewater-based epidemiology approach to estimate influenza incidence, predicting community outbreaks about one week earlier than publicly available data. The method also enables separate estimation of influenza A and B trends, supporting more detailed monitoring of seasonal outbreaks.

SourceThe University of Osaka·JournalWater and Environment Journal·TypeObservational study·DateMay 13, 2026

Why dolphins swim so fast: the secrets of eddies

A team of researchers from The University of Osaka used supercomputer simulations to study how vortices generated by dolphin kicks power fast swimming. They found that large, powerful vortices created by the movement of the dolphin's tail are responsible for most of the propulsion, while smaller ones contribute little to forward motion.

SourceThe University of Osaka·JournalPhysical Review Fluids·TypeData/statistical analysis·DateApr 27, 2026

An advance in single-chip, energy-efficient LEDs

Researchers at The University of Osaka developed a new LED structure that generates circularly polarized light from a single chip, reducing energy-conversion loss. This advancement could support smaller and more energy-efficient optical devices for next-generation technologies.

SourceThe University of Osaka·JournalOptical Materials Express·TypeComputational simulation/modeling·DateApr 14, 2026

Learning CBT form the inside out: Self-practice training program shows promise for future therapists

A new eight-week self-reflection program helps trainees deepen their understanding of cognitive behavioral therapy (CBT) and develop reflective skills. The study found that the program improved satisfaction, self-awareness, and reflective practice among participants, suggesting its potential to support CBT education.

SourceThe University of Osaka·TypeRandomized controlled/clinical trial·DateApr 7, 2026

World’s largest quantum circuit simulation for quantum chemistry achieved on 1,024 GPUs

Researchers have demonstrated a world-leading classical simulation of iterative quantum phase estimation circuits for quantum chemistry on up to 1,024 GPUs, expanding the scale of molecular systems available for the development and validation of quantum algorithms. This achievement supports progress toward industrial applications in dr...

SourceThe University of Osaka·TypeComputational simulation/modeling·DateMar 31, 2026

Building desktop particle accelerators to unlock new realms of research

The University of Osaka's researchers have achieved a key milestone in creating tabletop x-ray lasers by demonstrating free-electron laser amplification at extreme ultraviolet wavelengths. They used laser wakefield acceleration to generate high-quality, monoenergetic electron beams, enabling precise control of the plasma source.

SourceThe University of Osaka·JournalPhysical Review Research·TypeExperimental study·DateMar 31, 2026

Fujitsu and The University of Osaka develop new technologies for chemical material energy calculations on early-FTQC quantum computers

Researchers developed a new technology combining ver. 3 of the STAR architecture with molecular model optimization, significantly reducing computational resource requirements for chemical material design calculations. This breakthrough enables realistic energy calculations using early-FTQC quantum computers within a practical timeframe.

SourceThe University of Osaka·TypeComputational simulation/modeling·DateMar 29, 2026

Location, location, location: For potassium channels, it depends on functionality

Potassium KCNQ2/3 channels need full functionality to work properly in the brain and reach their correct location. This is linked to their regulation by protein ankG. Altering channel functionality affects neuronal excitability and may contribute to developing new therapeutic strategies for epilepsy.

SourceThe University of Osaka·JournalProceedings of the National Academy of Sciences·TypeImaging analysis·DateMar 3, 2026

Yes! The role of YAP and CTGF as potential therapeutic targets for preventing severe liver disease

A study from The University of Osaka reveals a molecular pathway connecting liver congestion to liver fibrosis, portal hypertension, and liver tumorigenesis. Researchers identified increased activity of YAP and CTGF in liver sinusoidal endothelial cells as key molecules involved in this signaling pathway.

SourceThe University of Osaka·JournalGastroenterology·TypeExperimental study·DateFeb 27, 2026

Here we grow: chondrocytes’ behavior reveals novel targets for bone growth disorders

A team at The University of Osaka has identified a signaling molecule called FGFR3 and a pathway called CREB as key in regulating bone growth. Cells carrying the genetic mutation associated with achondroplasia accumulate in the resting zone and show abnormal behaviors, which included abnormal patterns of division and migration.

SourceThe University of Osaka·JournalNature Communications·TypeExperimental study·DateFeb 26, 2026

A clearer future: Researchers unveil transparent, plastic-free wood

Scientists at The University of Osaka develop transparent, plastic-free wood without lignin or additives, showcasing the crucial role of cellulose microfibril skeleton alignment in achieving transparency. This breakthrough paves the way for sustainable transparent materials with applications in energy-efficient buildings and devices.

SourceThe University of Osaka·JournalMacromolecular Materials and Engineering·TypeExperimental study·DateFeb 17, 2026

Real-time imaging of contact between cells and between a single neuron’s extensions

Scientists from The University of Osaka have created two new fluorescent markers, Gachapin and Gachapin-C, that can visualize dynamic cell-to-cell contacts and connections within a single neuron's extensions. These indicators allow for the monitoring of complex patterns of connectivity in various cell types, including neurons.

SourceThe University of Osaka·JournalCell Reports Methods·TypeExperimental study·DateJan 28, 2026

Wastewater surveillance reveals true scale of COVID-19 spread as clinical testing declines

A study in Japan found that wastewater surveillance can uncover the true scale of COVID-19 spread by detecting high viral loads in sewage despite reduced clinical testing. This approach offers an objective view of community-wide infection levels, unaffected by changes in testing policies or public behavior.

SourceThe University of Osaka·JournalEnvironment International·TypeObservational study·DateJan 28, 2026

On the energy loss maximization in gas-liquid two-phase flows driven by rotors

The study reveals that torque maximization arises from both direct collisions and pressure imbalances in gas-liquid interface waves. This phenomenon is significant for energy savings and optimal design in complex industrial equipment, such as power transmission devices, cooling systems, and chemical agitators.

SourceThe University of Osaka·JournalMultiphase Science and Technology·TypeComputational simulation/modeling·DateDec 15, 2025

Simple gel jelly beads on a liquid surface reveal secrets of slow earthquakes

Scientists at The University of Osaka reproduced multiple statistical characteristics of slow earthquakes using gel jelly beads on a liquid surface. The study suggests that slow earthquakes exhibit anomalously long and small slips adjacent to regular earthquakes, with potential implications for probabilistic earthquake assessments.

SourceThe University of Osaka·JournalNature Communications·TypeExperimental study·DateDec 1, 2025

The hidden rule behind ignition — An analytic law governing multi-shock implosions for ultrahigh compression

Researchers have developed a new framework that governs the hidden rule behind stacked-shock implosions, allowing for efficient and scalable compression. This work extends classical theory into modern high-energy-density regimes, revealing a natural harmony underlying extreme physics processes.

SourceThe University of Osaka·JournalPhysical Review E·TypeComputational simulation/modeling·DateNov 18, 2025