A team of researchers from The University of Osaka used supercomputer simulations to study how vortices generated by dolphin kicks power fast swimming. They found that large, powerful vortices created by the movement of the dolphin's tail are responsible for most of the propulsion, while smaller ones contribute little to forward motion.
A new catalyst converts carbon dioxide into carbon monoxide under mild conditions, offering a potential path toward future low-energy carbon recycling technologies. The catalyst uses vibrational energy to drive chemical reactions, boasting high efficiency and selectivity for CO conversion.
Researchers at The University of Osaka developed a new LED structure that generates circularly polarized light from a single chip, reducing energy-conversion loss. This advancement could support smaller and more energy-efficient optical devices for next-generation technologies.
A new eight-week self-reflection program helps trainees deepen their understanding of cognitive behavioral therapy (CBT) and develop reflective skills. The study found that the program improved satisfaction, self-awareness, and reflective practice among participants, suggesting its potential to support CBT education.
Researchers have observed evidence of a new type of mesic nucleus, which could provide insight into the vacuum structure and mass generation mechanism. The discovery was made using a high-precision experiment at the GSI Helmholtzzentrum für Schwerionenforschung, Germany.
Researchers have demonstrated a world-leading classical simulation of iterative quantum phase estimation circuits for quantum chemistry on up to 1,024 GPUs, expanding the scale of molecular systems available for the development and validation of quantum algorithms. This achievement supports progress toward industrial applications in dr...
The University of Osaka's researchers have achieved a key milestone in creating tabletop x-ray lasers by demonstrating free-electron laser amplification at extreme ultraviolet wavelengths. They used laser wakefield acceleration to generate high-quality, monoenergetic electron beams, enabling precise control of the plasma source.
Researchers developed a new technology combining ver. 3 of the STAR architecture with molecular model optimization, significantly reducing computational resource requirements for chemical material design calculations. This breakthrough enables realistic energy calculations using early-FTQC quantum computers within a practical timeframe.
Researchers from The University of Osaka propose a compact LED design that directly emits circularly polarized light, potentially simplifying optical devices. The new design uses robust inorganic materials and achieves high levels of both efficiency and polarization degree.
Researchers found that NUTM1 rearranged leukemia is distinct from other forms, with decreased DNA methylation and increased lifespan of blood cells. Leukemias with BRD9-NUTM1 fusion are extremely sensitive to chemotherapy, leading to improved clinical outcomes.
Researchers at The University of Osaka developed a molecular design strategy to reconcile the trade-off between polymer material's durability and degradability. They created a tough material whose enzymatic degradation can be switched on or off using light, allowing for precise programming of its lifetime.
Researchers at The University of Osaka discovered that the cyanobacterial circadian clock is controlled by factors intrinsic to one protein, which remains stable under different conditions. This finding offers significant insight into how living organisms measure time.
Potassium KCNQ2/3 channels need full functionality to work properly in the brain and reach their correct location. This is linked to their regulation by protein ankG. Altering channel functionality affects neuronal excitability and may contribute to developing new therapeutic strategies for epilepsy.
A team of researchers at The University of Osaka has found a novel method for creating diastereomers, which are structurally identical molecules with different biological activities. Their approach uses a group-14 allylatrane to control the reaction, resulting in the high-yield synthesis of complex molecules.
A study from The University of Osaka reveals a molecular pathway connecting liver congestion to liver fibrosis, portal hypertension, and liver tumorigenesis. Researchers identified increased activity of YAP and CTGF in liver sinusoidal endothelial cells as key molecules involved in this signaling pathway.
A team at The University of Osaka has identified a signaling molecule called FGFR3 and a pathway called CREB as key in regulating bone growth. Cells carrying the genetic mutation associated with achondroplasia accumulate in the resting zone and show abnormal behaviors, which included abnormal patterns of division and migration.
Researchers at The University of Osaka developed a solid-state analogue that enables the formation of subnanometer pores approaching biological ion-channel dimensions. The team demonstrated the opening and closing process hundreds of times, with spikes in current consistent with biological channels.
Scientists at The University of Osaka develop transparent, plastic-free wood without lignin or additives, showcasing the crucial role of cellulose microfibril skeleton alignment in achieving transparency. This breakthrough paves the way for sustainable transparent materials with applications in energy-efficient buildings and devices.
Researchers from The University of Osaka developed a novel device to harness wave power, achieving high energy absorption efficiency across broadband frequencies. By tuning gyroscopic parameters, the device can maximize performance, providing a roadmap for developing adaptable and efficient wave energy converters.
A team of researchers from The University of Osaka compared the way humans and machines think about words, finding some strong correlations but also significant discrepancies. Human ratings varied widely across words like prepositions and conjunctions, while LLMs tended to assign consistently low ratings.
Scientists from The University of Osaka have created two new fluorescent markers, Gachapin and Gachapin-C, that can visualize dynamic cell-to-cell contacts and connections within a single neuron's extensions. These indicators allow for the monitoring of complex patterns of connectivity in various cell types, including neurons.
A study in Japan found that wastewater surveillance can uncover the true scale of COVID-19 spread by detecting high viral loads in sewage despite reduced clinical testing. This approach offers an objective view of community-wide infection levels, unaffected by changes in testing policies or public behavior.
Researchers have demonstrated that Janus nanoparticles can disrupt drug-resistant bacteria's defenses, restoring the effectiveness of conventional antibiotics. The approach uses nanoparticles to create pores in bacterial membranes, allowing antibiotics to flood in and execute their killing function.
Researchers from The University of Osaka discovered that loss of heterochromatin can trigger genetic changes leading to chromosomal rearrangements and diseases like cancer. Accumulation of R-loops at pericentromeric repeats was found to be a key mechanism in this process.
A research team at The University of Osaka has identified a parallel pathway involving CENP-C for centromere specification and function. This process is vital for ensuring chromosomes are structured and genes are expressed appropriately.
Professor Keisuke Fujii, a researcher at The University of Osaka, has been selected as one of the Quantum 100 for his work on quantum computing. He was honored with this recognition in 2025, the centennial year of quantum mechanics.
The study reveals that torque maximization arises from both direct collisions and pressure imbalances in gas-liquid interface waves. This phenomenon is significant for energy savings and optimal design in complex industrial equipment, such as power transmission devices, cooling systems, and chemical agitators.
Researchers have created a simple and efficient system to understand norovirus gene functions, enabling the development of antivirals and vaccines. The new method involves injecting norovirus cDNA clones into zebrafish embryos to generate infectious human noroviruses.
Researchers from The University of Osaka found that blood sugar migration to saliva in individuals with type 2 diabetes causes an imbalance in the oral microbiome, leading to cavity development. Improved glycemic control reduces this imbalance and the risk of tooth decay.
Scientists at The University of Osaka reproduced multiple statistical characteristics of slow earthquakes using gel jelly beads on a liquid surface. The study suggests that slow earthquakes exhibit anomalously long and small slips adjacent to regular earthquakes, with potential implications for probabilistic earthquake assessments.
Researchers at The University of Osaka have developed a new reaction using main-group element gallium to synthesize important building-block molecules. The discovery uses earth-abundant elements, potentially easing reliance on rare-earth metals and reducing environmental costs.
A comprehensive dataset detailing Japanese adults' responses to the pandemic offers unprecedented insights into public attitudes and behaviors. The 30-wave panel survey captures how risk perception, preventive behaviors, and psychological distress evolved over four years.
Researchers have developed a new framework that governs the hidden rule behind stacked-shock implosions, allowing for efficient and scalable compression. This work extends classical theory into modern high-energy-density regimes, revealing a natural harmony underlying extreme physics processes.
Researchers at The University of Osaka have developed a novel Balloon-Assisted Bronchoscope Delivery (BDBD) technique, enabling safe access to small, early-stage lung cancers hidden in the peripheral lung fields. This innovation promises to revolutionize both early diagnosis and minimally invasive treatment.
Researchers have discovered a key factor that determines whether a lithium-ion battery can charge and discharge reversibly, enabling the rational design of electrolytes. The new metric enables efficient prediction of an electrolyte's suitability and accelerates improvements in battery performance.
The University of Osaka and NEC have demonstrated a wide-area distributed campus AI processing platform, enabling on-demand use of GPUs from compute servers via an optical network. This platform leverages NEC's ExpEther technology to connect and disconnect devices across campus, improving efficiency and optimizing GPU utilization.
Scientists at The University of Osaka developed a novel hydrogel that supports the efficient 3D culture of human induced pluripotent stem cells. This new material combines the properties of fibrin and laminin-511, creating a potent, xeno-free scaffold with strong cell adhesion.
Researchers at The University of Osaka have developed an eco-friendly method to produce highly stable and biocompatible gold nanoparticles using microalgae. This breakthrough enables the creation of safer and more effective cancer therapies with fewer side effects for patients.
Researchers have discovered how key molecules coordinate chromosome alignment in cell division. Dual inhibition of KIF18A and CENP-E selectively kills cancer cells, suggesting a new therapeutic avenue for cancer treatment. This study highlights the importance of targeting specific proteins to develop more effective anticancer therapies.
A randomized clinical trial has shown that rituximab is effective in preventing relapses and reducing the need for corticosteroids in adults with relapsing nephrotic syndrome. The study involved 66 adult patients treated with either rituximab or a placebo, with impressive results at the 49-week follow-up.
Researchers from The University of Osaka developed MicroAdapt, a groundbreaking self-evolving edge AI technology that enables real-time learning and forecasting capabilities within compact devices. It achieves up to 100,000 times faster processing and 60% higher accuracy compared to state-of-the-art deep learning methods.
Researchers from The University of Osaka and The University of Tokyo have developed a novel technology that visualizes specific molecules inside living cells using light. The new photo-responsive alkyne tag enables precise visualization without disrupting molecular dynamics.
Scientists at The University of Osaka have developed an innovative method for producing NOBIN, a valuable molecule used in pharmaceuticals, by combining a vanadium catalyst and LED light. This clean process yields only water as a byproduct, showcasing exceptional environmental compatibility and waste reduction.
Researchers from The University of Osaka develop a groundbreaking synthetic method to incorporate boron-rich carboranes into aromatic compounds, eliminating complex steps and hazardous conditions. This 'dump-and-stir' technique enables large-scale production using inexpensive aryl bromides and chlorides.
Researchers from the University of Osaka have identified a crucial protein, TMEM217, that regulates sperm movement. By restoring the signal, they successfully treated immotile sperm and enabled them to fertilize eggs in vitro, leading to healthy births.
Researchers at The University of Osaka developed an mRNA therapy that restored sperm production and achieved the birth of viable offspring in a mouse model. This treatment showed promise for treating non-obstructive azoospermia, a genetic condition causing male infertility.
Researchers at The University of Osaka have identified a previously uncharacterized subset of immune cells called preTfr that play a critical role in preventing autoantibody production. In patients with severe COVID-19, these cells are significantly reduced, correlating with increased levels of harmful autoantibodies.
Professor Sakaguchi's Nobel Prize win recognizes his groundbreaking research on regulatory T cells, crucial for preventing excessive inflammation and autoimmune reactions. His work aims to develop new treatments for autoimmune diseases, allergies, cancer, and other conditions.
Scientists at The University of Osaka developed a polymeric adhesive that can be reused repeatedly by introducing reversible bonds into the interface. This technology could improve manufacturing yield, reduce costs and minimize waste.
Researchers at The University of Osaka developed a reinforcement learning framework to enable spoken dialogue systems to acquire new vocabulary efficiently while minimizing user interruption. This approach improves word segmentation performance while reducing the number of questions asked.