A new report reveals that both Democrats and Republicans personally value core democratic principles, but severely underestimate opposing party members' support for those same characteristics. This biased underestimation leads to a willingness to subvert democratic principles, particularly among Republicans.
Researchers at University of Illinois Chicago found that opioid deaths in Cook County have been undercounted by up to 15%, with the majority of missed cases occurring in hospitals. The study highlights the need for better data collection and reporting to combat the opioid crisis.
A new rodent study found that low doses of alcohol can trigger epigenomic and transcriptomic changes in the brain, creating an epigenetic pathway for addiction. The research suggests that even small quantities of alcohol can prime the brain for addiction, regardless of sex or quantity.
Researchers at University of Illinois Chicago developed a method to convert 100% of captured carbon dioxide into ethylene, producing hydrocarbons with high purity. The process uses electrolysis and can recycle almost all carbon dioxide captured, making it carbon negative when powered by renewable energy.
The Midwest Antiviral Drug Discovery Center, led by the University of Minnesota, aims to discover effective responses to pandemics through basic, translational, and clinical research. Researchers at UIC are developing an antiviral therapy for filoviruses like Ebola with a potential drug ready for human testing within three to five years.
A team of scientists from the University of Illinois Chicago discovered that hydrogen ions, not zinc, cause damage to manganese dioxide in rechargeable aqueous zinc-manganese batteries. This finding challenges existing knowledge about the charging mechanism and opens up new strategies for improving battery sustainability.
Researchers examine voting decisions when favored candidates commit moral transgressions, identifying key factors affecting support. Strong ideological identity and severity of transgression influence voter loyalty, with significant differences between conservatives and liberals.
A multisite clinical trial will deliver behavioral interventions to over 1,000 adults aged 50 and older with excess weight and cardiometabolic risk factors. The adaptive treatment model tests an evidence-based video program against a program with problem-solving therapy delivered via videoconferencing.
Engineers at UIC have been awarded a grant to build a system that selectively removes and destroys PFAS, commonly called 'forever chemicals,' from industrial and municipal wastewaters. The team will develop a prototype of their system and deploy it for scale-up and pilot testing in California's Orange County Water District.
Researchers are investigating new methods to reduce carbon dioxide emissions from cement manufacturing, aiming to create a carbon-negative replacement for portland cement. A sustainable way to produce calcium hydroxide is also being developed, which could significantly lower the carbon footprint of the existing cement industry.
Researchers found an association between estimated groundwater arsenic concentration and risk of low birth weight, suggesting efforts to reduce arsenic in private wells could help more babies be born at healthy weights. The study used machine learning algorithms to estimate arsenic levels in nearly all US counties.
A new analysis published in JAMA Psychiatry shows that brief suicide prevention interventions delivered in healthcare settings drastically underreport the strategies needed for successful implementation. On average, about 85% of these strategies were missing from published reports.
Researchers identified immune endothelial cells promoting inflammation and developmental endothelial cells supporting cell development, regeneration, and proliferation. The study's findings may lead to targeted treatments for lung infections and acute respiratory distress syndrome.
Researchers analyzed data from 599 patients with premenstrual dysphoric disorder and found that 34% have attempted suicide, with high rates of suicidal ideation, planning, and self-injury among women. The study highlights the need for accurate diagnosis and screening of suicidal ideation in patients with PMDD.
The University of Illinois Chicago has joined the Co-design Center for Quantum Advantage, a US Department of Energy-funded center focused on building scalable quantum computer systems. The partnership will open new opportunities for UIC students in quantum engineering and collaboration with researchers.
Researchers argue that national strategies ignore pandemic's early lessons on chronic diseases and their disproportionate impact on underserved populations. They recommend incorporating prevention and control of chronic diseases into existing policies.
Researchers at the University of Illinois Chicago found that gene editing can reverse epigenetic changes in the brain caused by adolescent binge drinking, leading to a decrease in anxiety and excessive drinking behavior. The study used CRISPR-dCas9 technology to manipulate histone acetylation and methylation processes at the Arc gene.
A study from the University of Illinois Chicago explores key themes and topics from COVID-19 vaccine-related tweets, identifying changes in public attitudes towards vaccination and concerns about effectiveness. The research provides insights for policymakers to frame policies and programs to accelerate vaccine uptake.
A new study has found a clear link between silica exposure and severe black lung disease in contemporary coal miners. The researchers attributed the resurgence of progressive massive fibrosis to changes in mining technology, such as mechanized coal extraction devices introduced in the 1950s.
Researchers at the University of Illinois Chicago are studying licorice-derived substances for their potential to prevent or stop prostate cancer growth. The study suggests that these compounds, such as glycyrrhizin and its derivatives, may have anti-inflammatory and anti-cancer effects.
Scientists create nanoparticles coated in mannose to block production of scar-promoting protein in lung cells. The treatment holds promise for preventing severe lung scarring disease.
Researchers at the University of Illinois Chicago have identified two distinct subtypes of neutrophils, with one subtype being a drug target for treating inflammatory diseases. The discovery paves the way for more targeted therapies that address chronic inflammation without suppressing anti-infection functions.
Scientists at the University of Illinois Chicago have created a new family of environmentally safe, frost-resistant coatings that can delay the formation of frost for extended hours. These coatings can be applied to various surfaces without preconditioning or expensive surface treatments, reducing pollution and ice-related problems.
Engineers at University of Illinois Chicago develop additive material to make inexpensive iron-nitrogen-carbon fuel cell catalysts more durable. The material scavenge and deactivate free radicals, reducing corrosion and degradation in fuel cells.
Researchers at the University of Illinois Chicago have developed a new cell-laden bioink that enables the production of complex, shape-changing bioconstructs. These 4D constructs have the potential to mimic the body's natural developmental processes and could lead to advances in tissue engineering.
Researchers at University of Illinois Chicago are studying long COVID-19 in adults, focusing on vulnerable communities in urban and rural areas. They aim to understand factors that make individuals vulnerable and protective against long-term effects.
Intermittent fasting produces mild to moderate weight loss and improves cardiometabolic risk factors, comparable to traditional calorie-restricted diets. The review also dispels myths about intermittent fasting, including the misconception that it leads to weakness and decreased concentration.
Researchers found early and persistent activation of neutrophils in patients who developed severe COVID-19. The study suggests that identifying specific gene signatures could lead to effective treatments targeting high-risk patients. This discovery may also inform the development of simple blood tests to prioritize treatment.
A study led by University of Illinois Chicago researchers found that structural racism can result in poorer leukemia outcomes for Black and Hispanic patients. Neighborhood disadvantage was a significant predictor of leukemia-specific death, accounting for nearly all the Black-white disparity in AML-related death.
Researchers found that it took nearly three years for these drugs and biologics to be incorporated into clinical guidelines, highlighting a significant delay in patient access. The study suggests that expedited approval processes are only the first step, and planning ahead is crucial to bring needed treatments to patients.
Researchers at the University of Illinois Chicago found a promising treatment for neurodegenerative diseases by stopping nerve cell degeneration. A peptide has been identified that inhibits mitochondrial fission and lets nerve cells grow normally.
Researchers at the University of Illinois Chicago have developed a compound that may offer hope for pancreatic cancer treatment. The experimental compound, XP-524, has been shown to more than double the average survival time for mice with pancreatic cancer when combined with immunotherapy.
A cost-effective artificial leaf from the University of Illinois Chicago can capture carbon dioxide at rates 100 times better than current systems. It works in real-world environments and releases CO2 for fuel and materials.
Researchers at University of Illinois Chicago identified changes in the gut microbiome that can lead to gestational diabetes. They found a specific metabolite, kynurenine, that is increased during pregnancy and contributes to insulin resistance.
A recent study found that 84% of adults with asthma experience discomfort while wearing a mask, and 75% report trouble breathing or shortness of breath. The study also discovered an association between poorer asthma control and higher symptoms while wearing a mask.
A newly developed decoy protein has been found to be highly effective in preventing death and lung damage in humanized animal models of severe COVID-19 disease. The treatment works by competing for the spike protein of SARS-CoV-2, thereby neutralizing the virus before it can bind and enter cells.
The UIC Center for Healthy Work will continue its efforts to improve the health of low-wage workers with a five-year, $7 million grant. Researchers will advance their work with community members and expand collaborations across systems-level partners to empower workers.
Researchers at the University of Illinois Chicago have developed a new method for analyzing pyroptosis, a process of cell death previously thought to be irreversible. By using optogenetic gasdermin, they found that certain conditions can trigger pores to close within tens of seconds, suggesting the process dynamically self-regulates.
Researchers have developed an at-home COVID-19 test with a high-quality assay that can detect the virus with similar reliability to laboratory-based molecular tests. The new test uses loop-mediated isothermal amplification and has unique advantages, such as speed and direct detection of viral RNA in saliva.
A new study has identified a biomarker for depression and antidepressant response in human platelets. The biomarker can be detected through a blood test and may indicate therapeutic response within one week of treatment.
A recent study published in Frontiers in Cellular and Infection Microbiology found a significant increase in sexually transmitted infections (STIs) among girls and young women in western Kenya, coinciding with the COVID-19 pandemic. Researchers attribute this rise to increased stress-related changes in the vaginal microbiome.
Two new studies published by researchers at the University of Illinois Chicago show that sugar-sweetened beverages taxes are effective and sustainable in reducing consumption. The Seattle data analysis found a 59% tax pass-through rate, a 22% reduction in volume sold of taxed beverages, and a net 19% reduction in grams of sugar sold fr...
A simple change in the way donor cells are processed can maximize a single cell's production of extracellular vesicles, which are small nanoparticles naturally secreted by cells. The finding offers new avenues for research around cellular therapies, where transplanted cells are used to help the body heal or work better.
The study found that applying an electrical potential can stabilize high-temperature superconducting superhydrides at much lower pressures than previously thought. This new method could lead to the creation of new materials with broad applications in consumer and industrial sectors.
A new study reveals that iboxamycin effectively fights both gram-negative and gram-positive drug-resistant bacteria in mouse models. The researchers discovered the molecular mechanism that allows this drug to overcome resistance, which is important for developing new antibiotics.
A University of Illinois Chicago clinical trial aims to evaluate the impact of a healthy diet on asthma management in adults. Participants with uncontrolled asthma will be assigned to either an education-only group or a group receiving dietary counseling and guidance on the DASH eating plan, a diet approach proven for hypertension mana...
University of Illinois Chicago researchers discovered a function of mammalian target of rapamycin complex 2 in an antiviral defense mechanism, limiting HSV-1 virus infection through rapid activation of antiviral immunity. The protein complex protects the host by preventing encephalitis and possible death due to HSV-1 infection.
A review of 25 studies on intermittent fasting found that all forms produced mild to moderate weight loss, similar to traditional calorie-restrictive diets. Intermittent fasting regimens also showed benefits in decreasing blood pressure and insulin resistance, and improving appetite regulation.
A pre-clinical study by University of Illinois Chicago researchers shows that a drug targeting specific immune pathways can prevent lung damage and death in mice infected with the SARS-CoV-2 virus. The study suggests targeted treatments may be more suitable for COVID-19 patients than broad immune suppressants.
Researchers at UIC will evaluate the effectiveness of integrated behavioral health care coordination on mental health outcomes for teens with intellectual and developmental disabilities. The study aims to identify better care coordination models to reduce barriers to access to behavioral health care for this vulnerable population.