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University of Nottingham


Hormone discovery could predict long term health of men

A novel insulin-like peptide hormone, INSL3, remains consistent throughout a man's life, making it a reliable predictive biomarker for age-linked disease. High levels of INSL3 in young men correlate with a range of age-related illnesses, while low levels increase the risk of acquiring these diseases.

SourceUniversity of Nottingham·JournalFrontiers in Endocrinology·TypeExperimental study·DateNov 8, 2022

Lianas more likely to infest smaller trees in Southeast Asian forests, transforming knowledge in understudied area

Research finds that lianas more frequently infest smaller trees in Southeast Asian forests, hindering their growth. This study transforms understanding of tropical forests and their role in the global carbon cycle. Lianas' impact on climate change is significant due to their ability to reduce carbon uptake and storage.

SourceUniversity of Nottingham·JournalJournal of Ecology·TypeObservational study·DateNov 7, 2022

A major clinical trial shows how to reduce the risk of stomach bleeding occasionally caused by regular aspirin use

A major clinical trial found that a short course of antibiotics can significantly reduce the risk of stomach bleeding caused by regular aspirin use, potentially improving its safety. The study involved 30,166 patients taking aspirin and showed rapid protection from hospital admissions for ulcer bleeding.

SourceUniversity of Nottingham·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateNov 3, 2022

New research shows link between workplace bullying and conspiracy beliefs

A new study by the University of Nottingham reveals that people who experience workplace bullying are more likely to engage in conspiracy theorizing. The research found that both bullying and conspiracy theories share similar psychological factors, such as feelings of paranoia. This can lead to a vicious cycle where victims of bullying...

SourceUniversity of Nottingham·JournalSocial Psychology·TypeExperimental study·DateOct 26, 2022

A new study gives an important understanding of how molecular motor proteins are involved in malaria transmission

A new study published in PLOS Biology reveals the significance of kinesins in basic cellular processes needed for malaria parasite development, multiplication and invasion. Researchers found that eight out of nine kinesins present in the parasite genome are required for cell proliferation to cell movement in mosquito hosts.

SourceUniversity of Nottingham·JournalPLOS Biology·TypeExperimental study·DateJul 28, 2022

Evidence that asylum seekers are facing human rights violations in Croatia is now incontestable, says new study

Researchers found evidence of extreme police brutality and forced expulsions of hundreds of asylum seekers from Croatia, with over 25,000 people affected. The study also reveals the use of 'chain pushbacks' involving multiple EU countries and Croatian police violence against migrants.

SourceUniversity of Nottingham·JournalAnnals of the American Association of Geographers·TypeObservational study·DateJul 21, 2022

New material for surgical dressings shown to prevent recurrence of melanoma and enhance healing

Scientists at the University of Nottingham have developed a new dressing that can prevent the recurrence of melanoma by killing cancer cells while promoting healthy cell growth. The dressing is made with graphene oxide, elastin, and ethanol, and requires only 15 seconds of Near Infrared light every 48 hours to be effective.

SourceUniversity of Nottingham·JournalAdvanced Functional Materials·TypeExperimental study·DateJul 13, 2022

Interrupting the treatment of vulnerable people on immune-suppressing medicines, doubles their antibody response to COVID-19 booster vaccination

A clinical trial found that interrupting treatment with methotrexate, a common immune-suppressing drug, doubles the antibody response to COVID-19 booster vaccinations in vulnerable individuals. This improvement is maintained over a 3-month period and has no adverse impact on quality of life.

SourceUniversity of Nottingham·JournalThe Lancet Respiratory Medicine·TypeExperimental study·DateJun 27, 2022

Traditional native Indian medicine is effective in treatment of type 2 diabetes, says new study

A new study published in Frontiers in Pharmacology found that traditional Ayurvedic medicines are effective in maintaining blood sugar levels in patients with type 2 diabetes. The review analyzed 219 articles and included 98 Ayurvedic medicines, showing benefits in glycemic control, body weight, and other diabetes-related parameters.

SourceUniversity of Nottingham·JournalFrontiers in Pharmacology·TypeSystematic review·DateJun 8, 2022

Colossal collisions linked to solar system science

A new study using Chandra X-ray Observatory data reveals a deep connection between cosmic collisions and solar system phenomena. The research, led by Helen Russell from the University of Nottingham, shows that electrons are heated by compression of gas in galaxy clusters.

SourceUniversity of Nottingham·JournalMonthly Notices of the Royal Astronomical Society·TypeObservational study·DateJun 7, 2022

Death from alcohol-related liver disease could be prevented with early diagnosis and intervention, says new study

A new UK study found that people dying from alcohol-related liver disease had an average of 25 hospital interactions prior to their death, highlighting missed opportunities for intervention. Early diagnosis and treatment can prevent mortality from ARLD, which is a significant cause of deaths globally.

SourceUniversity of Nottingham·JournalDrug and Alcohol Review·TypeData/statistical analysis·DateMay 31, 2022

Metals found in people’s urine could detect acute kidney injury in very early stages, says new study

Scientists have discovered that certain metals found in people's urine could be potentially useful clinical biomarkers for the early detection of acute kidney injury (AKI). The study, which was led by experts from the University of Nottingham, found that concentrations of these metals rose in urine within an hour after cardiac surgery ...

SourceUniversity of Nottingham·JournalKidney International Reports·TypeExperimental study·DateMay 30, 2022

Scientists use machine learning to identify antibiotic resistant bacteria that can spread between animals, humans and the environment

A ground-breaking software combines DNA sequencing and machine learning to identify antibiotic-resistant bacteria transmission between humans, animals, and the environment. The study found antimicrobial genes shared across animals, farm workers, and environments, including unknown genes associated with resistance.

SourceUniversity of Nottingham·JournalPLOS Computational Biology·TypeData/statistical analysis·DateApr 21, 2022

Vegetable oil emissions study reveals urgent need for greener growing solutions

A global study reveals the extent of greenhouse gas emissions from vegetable oil production, emphasizing the need for sustainable growing practices. The study found that land use contributes significantly to emissions, with rapeseed and sunflower oil systems appearing more sustainable than palm and soybean oil.

SourceUniversity of Nottingham·JournalScience of The Total Environment·TypeMeta-analysis·DateMar 21, 2022

The shape of bacteria can make it a more effective, and useful predator, says a new study

A new study reveals that the curved shape of a predatory bacterium enables it to efficiently invade and consume harmful bugs like E.coli and Salmonella. The bacterium, called Bdellovibrio bacteriovorus, uses a specialized protein to sculpt its own shape, allowing it to fit into prey cells and grow inside them.

SourceUniversity of Nottingham·JournalNature Communications·TypeExperimental study·DateMar 21, 2022

Home care can help with the recovery of people with schizophrenia in low- income countries

A study in rural Ethiopia found that community-based rehabilitation, supported by local health centers and medication, reduced symptoms and improved functioning for individuals with schizophrenia. Community-based rehabilitation workers also helped participants access healthcare services and support their families.

SourceUniversity of Nottingham·JournalThe Lancet Global Health·TypeRandomized controlled/clinical trial·DateMar 15, 2022

Unprecedented Australian bushfire intensity linked to British colonisation

A new study found that Australian bushfires are linked to British colonisation and climate change, with forests becoming denser and more flammable due to the increase in woody biomass. Indigenous burning practices ceased after colonial settlement, leading to an increase in shrub cover and unprecedented wildfires.

SourceUniversity of Nottingham·JournalFrontiers in Ecology and the Environment·TypeComputational simulation/modeling·DateFeb 15, 2022

Pulse oximeter measurements of blood oxygen levels are unreliable in assessing severity of Covid-19 pneumonia across different ethnic groups

A study published in European Respiratory Journal found pulse oximeters give false readings of up to 7% higher in patients with Mixed, Black, and Asian ethnicities compared to White patients. This can delay timely treatment for Covid-19 pneumonia, leading to poorer outcomes.

SourceUniversity of Nottingham·JournalEuropean Respiratory Journal·TypeExperimental study·DateJan 27, 2022

Stress associated with an increased risk of getting Covid-19, study finds

A new study found that people experiencing increased stress, anxiety, and depression during the pandemic were more likely to contract Covid-19 and experience severe symptoms. The research, led by Professor Kavita Vedhara, suggests that psychological distress may be a significant factor in increasing susceptibility to viral respiratory ...

SourceUniversity of Nottingham·JournalAnnals of Behavioral Medicine·TypeObservational study·DateJan 12, 2022

New process makes every atom matter for sustainable catalyst production

Scientists have discovered a new process to break bulk metal into atoms for sustainable catalyst production. The method uses magnetron sputtering to achieve record-breaking rates of atom dispersal, enabling the fabrication of valuable catalyst materials. This breakthrough has significant implications for industries reliant on catalysts.

SourceUniversity of Nottingham·JournalJournal of Materials Chemistry A·TypeExperimental study·DateNov 23, 2021

Plant-derived antiviral drug is effective in blocking highly infectious SARS-CoV-2 Delta variant, say scientists

Scientists at the University of Nottingham found a plant-based antiviral treatment to be effective in blocking the highly infectious SARS-CoV-2 Delta variant. The novel natural antiviral drug, thapsigargin, was shown to trigger a broad-spectrum host-centred antiviral innate immune response against all variants of the virus.

SourceUniversity of Nottingham·JournalVirulence·TypeExperimental study·DateNov 19, 2021

A commonly found parasite could treat certain types of cancer, say scientists

Researchers found that Toxoplasma gondii, a commonly found parasite, can 'tame' the parasite to induce inflammatory responses and make tumours more responsive to treatment with immune checkpoint inhibitors. This approach has shown promise in treating melanoma, Lewis lung carcinoma, and colon adenocarcinoma in mouse models.

SourceUniversity of Nottingham·JournalJournal for ImmunoTherapy of Cancer·TypeExperimental study·DateNov 2, 2021

Scientists gain new understanding of how brain cells talk - which could help in the treatment of mental health conditions and memory diseases

Scientists have discovered that reversing molecular message modification at synapses may contribute to reversible mental health conditions like anxiety and memory diseases such as dementia. The findings, published in Molecular Psychiatry, are a major step in understanding brain cell communication.

SourceUniversity of Nottingham·JournalMolecular Psychiatry·TypeExperimental study·DateOct 18, 2021

New study sheds light on molecular motion

Scientists have developed a synthetic fibre that guides molecular movement fueled by light over long distances, paving the way for new sustainable energy sources and applications in medicine and chemical tasks. The system emulates cellular fibres, allowing for controlled transport of molecules using light as energy.

SourceUniversity of Nottingham·JournalNature Chemistry·TypeExperimental study·DateOct 11, 2021