Researchers at the University of Rochester Medical Center found that predicting movement is crucial for eye-and-hand coordination. The study used high-speed cameras and AI methods to analyze primate behavior and developed a detailed model of vision-guided reaching behavior.
Adolescent neurostimulation of dopamine circuitry may reverse genetic deficits in frontal cortex function, rescuing structural and behavioral deficits caused by disorders. Researchers identified critical windows in brain development where interventions can target and change the course of diseases.
A specialized weight loss program for Deaf people, designed and led by Deaf individuals, resulted in significant weight loss among participants. The Deaf Weight Wise program focused on lifestyle changes, social support, and cultural relevance, leading to a higher retention rate and better outcomes compared to mainstream programs.
A new study reveals that a Cas protein and a membrane protein work together to enhance anti-viral defense in bacteria. The team found that the membrane protein forms a pore-like structure that disrupts energy production and hinders virus replication, effectively 'pulling the plug' on viral infections.
New research shows that rhythmic brain activity helps organize transient bursts of activity in the brain to maintain short-term connections. Brain rhythms coordinate overlapping populations of neurons to store different pieces of information at the same time.
A study found that young adults who experienced gunshot, stab, or assault wounds as children have significantly higher rates of post-traumatic stress disorder (PTSD) than the general population. Ten respondents screened positive for probable PTSD, and nearly 17% reported persistent symptoms related to their injury.
Researchers have found that commercially available smartphones and smartwatches can capture key features of early, untreated Parkinson's disease. These technologies could provide more objective and continuous ways to measure the disease, bringing new treatments to market faster for patients in the early stages.
A team of researchers from the University of Rochester has discovered a molecule that guides T cells toward tumors, which could lead to improvements in CAR T-cell therapy for breast, lung, and brain cancers. The findings will help scientists develop a drug to manipulate this key protein, ST3GAL1, to ensure T cells hit their targets.
A recent study published in NeuroImage found that older adults with improved cognitive performance during dual-task walking had flexible neural resource allocation. This discovery suggests a potential method for tracking brain health and identifying individuals at risk of aging-related cognitive decline.
A study by University of Rochester Medical Center researchers reveals how a biological clock molecule contributes to lung scarring. Low levels of REV-ERBα have been linked to increased collagen production and worse lung damage in patients with pulmonary fibrosis.
Research suggests astrocytes integrate external sensory inputs with internal states to modify calcium signaling towards neurons. This process could be crucial for behavioral responses and memory formation.
A new study found that frequent COVID surveillance testing protected nursing home residents by detecting infected staff earlier, disrupting transmission chains. The research showed that high testing frequency facilities had clinically meaningful reductions in resident cases and deaths, particularly before vaccine availability.
A widely used dry cleaning chemical, trichloroethylene (TCE), may be fueling the rise of Parkinson's disease. Exposure to TCE has been linked to an increased risk of developing the condition, particularly among individuals who worked with or lived near contaminated sites.
A study found that gestational iron deficiency may contribute to cognitive impairments like autism, ADHD, and learning disabilities. Researchers identified a specific embryonic neuronal progenitor cell target for GID, which disrupts interneuron development.
Children with autism may not process visual illusions in the same way as their peers, indicating a potential issue with predicting and filling in missing visual information. This finding has implications for understanding and supporting individuals on the autism spectrum.
A new study found that polypharmacy, the concurrent use of multiple medications, increases the risk of adverse treatment outcomes in older adults with advanced cancer. Patients taking multiple medications had a 59% higher chance of stopping cancer treatment earlier than recommended.
Scientists identify ERBB2 pathway as key to promoting regeneration of cochlear hair cells, a crucial step towards treating hearing loss. The study's findings offer new hope for restoring auditory function after damage in mammals.
A pediatric trauma team at Golisano Children's Hospital significantly reduced unnecessary CT scans, minimizing radiation exposure and healthcare costs. The team's efforts, which included adapting existing guidelines and developing new ones, resulted in a 45% reduction in non-indicated scans.
Researchers have identified a previously unknown component of brain anatomy, dubbed SLYM, which acts as a protective barrier and immune monitoring platform. The discovery is expected to shed light on the glymphatic system's mechanisms and its potential role in brain diseases like Alzheimer's.
Researchers genetically engineered mitochondria to convert light energy into chemical energy, increasing ATP production and lifespan by 30-40%. The study provides new insights into mitochondrial function and offers a platform for studying age-related diseases.
A new study found that Black patients have lower odds of undergoing minimally invasive mitral valve surgery and higher odds of serious complications or death compared to white patients. This inequity is linked to factors such as Medicaid insurance, hospital resource, and surgeon experience.
Researchers discovered that trauma changes brain mechanisms involved in learning and survival, such as the salience network. The study found that people with PTSD struggle to distinguish between safe and dangerous stimuli when emotions are involved.
The FDA ban on flavored e-cigarettes did not lead to a significant decrease in adult vaping rates. In fact, many users switched to other flavored e-cigs or tobacco products. The study suggests that policy loopholes and the availability of newer products contributed to the failure of the ban.
Researchers discovered a molecular link between disrupted circadian rhythms and lung tumor growth, implicating a cancer-signature gene known as HSF1. Disrupted clocks may trigger lung tumors in individuals with irregular sleep patterns or night shifts.
Research in Zambia suggests children infected with HIV are more likely to struggle with cognitive and mental health issues despite well-controlled disease. Early intervention through better nutrition and antiretroviral therapies may improve neurological function.
Researchers discovered that even short-term exposure to diacetyl can cause lung damage when paired with a second insult like the flu. Mice exposed to low-level diacetyl over five consecutive days then infected with flu showed significant impairment of lung function and airway repair.
Researchers at the University of Rochester Medical Center used fMRI to study how the brain processes complex audiovisual speech. The study found that watching a narrator tell a story activates an extensive network of brain regions involved in sensory processing and cognitive functions associated with comprehension. This finding has pot...
Two new studies published in NEJM Catalyst demonstrate the remarkable effectiveness of telemedicine in addressing access barriers and improving health outcomes. The research highlights the benefits of telemedicine for patients with transportation challenges, mental health services, and overall quality of care.
Researchers at the University of Rochester Medical Center found that children who experience a mild traumatic brain injury are more likely to develop emotional and behavioral problems. The study, which analyzed data from thousands of children, revealed a 15-percent increased risk of these problems in kids with a mild TBI.
A new study has successfully predicted ovarian cancer in patients with a pelvic mass using a simple blood test. The liquid biopsy technology captures circulating tumor cells, allowing for genetic analysis in just a couple of hours, which can help diagnose the disease earlier.
A new study identifies how the suppression of a specific transcription gene triggers changes that impair oligodendrocyte function in Huntington's disease. The researchers believe replacing or fixing defective glia cells may prove a far easier proposition than replenishing neurons lost in the disease.
A study published in JAMA Health Forum found that COVID vaccine mandates for nursing home staff led to increased vaccination rates, with larger effects in Republican-leaning counties. The mandates did not significantly contribute to reported staffing shortages.
A new University of Rochester study compares two groups of patients with dental extractions, finding that a combination of non-opioid pain medications and gabapentin can minimize or eliminate opioids for dental pain. The results show promise for reducing opioid use during the COVID-19 pandemic.
Researchers found that children with autism process brain waves differently when focused on body movements versus colors, highlighting a key challenge in communication.
Researchers have discovered that inhibiting AKT, a key player in cell growth and survival, also decreases nonsense-mediated mRNA decay (NMD) in cells with fragile X syndrome. This finding provides new direction for developing treatments for the disorder and highlights the potential of existing drugs like Afuresertib.
Researchers found that walking enhances performance on cognitive tasks in 14 participants by increasing frontal brain function, while 12 others showed no improvement. This discovery highlights the flexibility of a healthy brain and has implications for understanding aging and neurological disorders.
A new study published in iScience found that the co-development of the gut microbiome, immune system, and respiratory system is correlated with a baby's respiratory health. Disruption of any of these systems resulted in greater respiratory morbidity for infants, highlighting the importance of timing in intervening with therapies.
A recent study found that 70% of adults with stage 3 or 4 cancer were at risk of drug-drug interactions, highlighting the importance of deprescribing medications to avoid harm. The study's results emphasize the need for education and problem-solving to address polypharmacy in older adults with cancer.
A new study found that states with less rigorous regulations have lower rates of residents dying at home or with hospice care. Dual Medicare-Medicaid status is also linked to worse access to high-quality end-of-life care.
The University of Rochester Recovery Center of Excellence brings together diverse experts to discuss strategies for overcoming stigma and health inequity barriers to substance use disorder care. The summit aims to address the 'fourth wave' of the opioid epidemic, driven by synthetic opioids and multiple substances in combination.
Researchers recommend daily steroid doses for children with Duchenne muscular dystrophy, finding improved motor and pulmonary functions in boys with the disease. The study suggests a standard of care is needed to establish benefits over potential side effects.
Research using Adolescent Brain Cognitive Development study data found that urban environments with socioeconomic challenges increase psychotic-like experiences in pre-adolescent children. Early prevention is crucial as these exposures are already present in late childhood.
A new study finds that fracking is linked to poor birth outcomes and contaminants in public drinking water. The research, which analyzed data from Pennsylvania between 2006 and 2015, shows a significant increase in preterm births and low birth weight among infants exposed to fracking-related chemicals.
New research suggests the brain uses multiple strategies to process smells, employing both snapshot-like and evolving ensemble approaches. The study provides new tools for scientists to quantify and interpret brain activity patterns.
A new study found significant improvement in survival rates of extremely pre-term babies born at 22 and 23 weeks. The study, which examined data from 2013-2018, showed a considerable increase in survival rates compared to previous studies, with survival rates reaching 30.0% at 22 weeks and 55.8% at 23 weeks.
Chronic pain may lead to changed eating behavior and obesity due to altered brain responses to sugar and fat. Brain scans reveal a smaller nucleus accumbens in patients with chronic pain who experience disrupted satiety signals.
Prenatal exposure to industrial toxin TCDD may cause long-term damage to brain circuits and potentially lead to neurodevelopmental disorders like autism and ADHD. Researchers found that pharmacological manipulation can restore microglia function, suggesting a possible therapeutic avenue for these disorders.
New research reveals the brain's flexibility in multitasking while walking, improving stability and performance. The study uses a Mobile Brain/Body Imaging system to record brain activity while participants walk on a treadmill or perform cognitive tasks.
Researchers discovered RNA can bind two metabolites in a single pocket, regulating gene expression and potentially creating new antibacterial drugs. This finding provides more support for the 'RNA World' theory, which suggests RNA molecules enabled life to evolve 3.5 billion years ago.
A study published in Cell Reports reveals a set of critical gene interactions that are common across many cancers. By using network modeling, researchers have pinpointed functionally relevant gene networks that could offer new cancer therapies.