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New study shows the potential of machine learning in the early identification of people with inflammatory arthritis

A Swansea University study reveals the potential of machine learning in identifying Ankylosing Spondylitis (AS) patients, reducing diagnosis delays from eight years to earlier. The research uses a national data repository to develop a predictive model for AS detection, empowering GPs to refer patients more efficiently.

SourceSwansea University·JournalPLOS ONE·TypeData/statistical analysis·DateApr 5, 2023

Who let the dingo out?

A team led by Bill Ballard has published a new study in GigaScience to propose Cooinda, an Alpine dingo, as the model specimen to represent a typical dingo. The study presents genomic and brain imaging data that sheds light on the evolutionary history of dingoes and their domestication process.

SourceGigaScience·JournalGigaScience·TypeMeta-analysis·DateApr 3, 2023

A printable multi-energy X-ray detector with high sensitivity

A printable multi-energy X-ray detector made from perovskite thin films has been developed with enhanced flexibility and sensitivity. The detector can operate in a broad energy range, from 0.1 KeV to tens of KeV, making it suitable for real-time detection and imaging applications such as disease diagnosis and explosives detection.

SourceARC Centre of Excellence in Exciton Science·JournalAdvanced Materials·TypeExperimental study·DateApr 2, 2023

The shape of your heart matters

Researchers from the Smidt Heart Institute found that individuals with spherical hearts are 31% more likely to develop atrial fibrillation and 24% more likely to develop cardiomyopathy. The study identified four genes associated with cardiomyopathy and a greater risk of developing atrial fibrillation.

World first: Researchers identify specific regions of the brain that are damaged by high blood pressure and are involved in a decline in mental processes and dementia

High blood pressure damages specific brain regions, including the putamen and white matter areas, leading to cognitive decline and increased risk of dementia. The study uses a combination of MRI, genetic analyses, and observational data to identify these affected regions.

SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·TypeObservational study·DateMar 27, 2023

New, non-invasive imaging tool maps uterine contractions during labor

Researchers developed a non-invasive imaging tool to create real-time images of uterine contractions during labor. The electromyometrial imaging (EMMI) technique provides detailed information on contraction patterns, which can help improve labor management and clinical decision-making.

SourceNIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development·JournalNature Communications·TypeObservational study·DateMar 14, 2023

NUS researchers develop new imaging approach to diagnose advanced form of non-alcoholic fatty liver disease

Researchers have developed a new imaging approach to diagnose advanced non-alcoholic fatty liver disease (NASH). The enzyme-sensitive nanoprobe emits signals that can be detected by MRI techniques, providing more accurate and sensitive data for diagnosis. This breakthrough aims to improve the treatment outcomes of NASH patients.

SourceNational University of Singapore, Yong Loo Lin School of Medicine·JournalACS Nano·TypeRandomized controlled/clinical trial·DateMar 9, 2023

Imaging the adolescent heart

A recent MRI study by the CNIC has established reference values for anatomical and functional parameters in adolescents' hearts, providing a crucial resource for clinical practice. The study involved 123 adolescents and aimed to fill the knowledge gap on 'normal' cardiac parameter values in this age group.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalEClinicalMedicine·TypeRandomized controlled/clinical trial·DateMar 3, 2023

More than 80% of American adults with type 2 diabetes meet treatment criteria for GLP-1 RAs or SGLT2is but most are not getting them

A study found that over 80% of American adults with type 2 diabetes meet the criteria to use GLP-1 RAs or SGLT2is, but only a small percentage are using them. The medications have a substantially higher cost than current first-line treatments, making it difficult for patients to access them.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateFeb 27, 2023

Troubling discovery

Researchers found that gadolinium nanoparticles from MRI contrast agents can infiltrate kidney cells, causing severe side effects like nephrogenic systemic fibrosis. The study used electron microscopy to detect tiny deposits of gadolinium in the kidneys of people who had been injected with contrast agents prior to their MRIs.

SourceUniversity of New Mexico Health Sciences Center·JournalScientific Reports·TypeExperimental study·DateFeb 16, 2023

Novel technique distinguishes between types of oral bone lesion based on MRI scan image texture

Researchers used MRI scans and texture analysis to differentiate between two types of benign oral bone lesions, ameloblastomas and odontogenic keratocysts. The study found that certain pixel and voxel organizational parameters in the MRI images were statistically significant, enabling more accurate diagnosis and treatment planning.

Researchers detail never-before-seen properties in a family of superconducting Kagome metals

Scientists have detailed the atomic structure of superconducting RbV3Sb5 at 103 degrees Kelvin, revealing a unique lattice pattern and charge-density wave. This breakthrough provides a new understanding of exotic states of matter and brings researchers closer to developing higher-temperature superconductors.

SourceBrown University·JournalPhysical Review Research·TypeExperimental study·DateFeb 10, 2023

MRI surveillance for postsurgical musculoskeletal soft-tissue sarcomas: AJR systematic review and meta-analysis

A systematic review and meta-analysis found that MRI-based surveillance after surgical treatment can detect clinically occult local recurrences, potentially improving patient outcomes. The study included 19 studies and showed a significant association between high-intensity surveillance and the detection of local recurrences.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeSystematic review·DateFeb 1, 2023

ICD detection and treatment of arrhythmias not impacted by MRI

A cohort study of over 600 persons with non-MRI-conditional implantable cardioverter defibrillators found that these devices continue to appropriately treat detected tachyarrhythmias after MRI scans. The findings suggest that patients with non-MRI-conditional ICDs can safely undergo MRI exams without compromising device function.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateJan 30, 2023

Researchers unveil new collection of human brain atlases that chart postnatal development

Researchers created monthly infant brain atlases to track normative trends in brain development. The atlases reveal changes in brain structure, cortical geometry, and tissue contrast, shedding light on conditions like ADHD and dyslexia. The study aims to facilitate discovery of new insights into child cognition and social behavior.

SourceUniversity of North Carolina Health Care·JournalNature Methods·TypeImaging analysis·DateJan 26, 2023

MRI-guided radiotherapy produces fewer side effects and better quality of life for patients with localized prostate cancer

A new study found that MRI-guided radiotherapy is more effective than CT-guided therapy in reducing side effects and improving quality of life for patients with localized prostate cancer. The trial involved 154 patients, who experienced fewer toxicities and better outcomes when treated with MRI guidance.

SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Oncology·TypeRandomized controlled/clinical trial·DateJan 12, 2023

How old is your brain, really? Artificial intelligence knows

A new AI model developed at USC accurately captures cognitive decline linked to neurodegenerative diseases like Alzheimer's much earlier than previous methods. The model analyzes MRI brain scans and detects subtle brain anatomy markers that correlate with cognitive decline, offering an unprecedented glimpse into human cognition.

SourceUniversity of Southern California·JournalProceedings of the National Academy of Sciences·TypeImaging analysis·DateJan 6, 2023

Researchers develop, validate tool to visualize 3D architectural properties of atherosclerosis plaques

Researchers developed an advanced MRI tool that reveals structural insights into atherothrombosis by detecting regions at risk of rupture or atherothrombosis. The tool provides new information on fatty material formation in arteries, improving diagnosis and treatment outcomes for individuals with atherosclerotic disease.

SourceBoston University School of Medicine·JournalJournal of Cardiovascular Magnetic Resonance·TypeExperimental study·DateJan 3, 2023

Pediatric outpatient non-contrast brain MRI: A cost analysis at three U.S. hospitals

A new study published in the American Journal of Roentgenology found significant cost savings by eliminating sedation during pediatric brain MRI examinations. The analysis calculated costs for sedated, nonsedated, and limited MRI exams at three US hospitals, revealing that labor costs were the largest expense category.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeImaging analysis·DateDec 21, 2022

Impaired glymphatic system may be linked with progression of Alzheimer's disease, finds new study

A new study found that impaired glymphatic system function is associated with Alzheimer's disease progression. Noninvasive MRI measures of the glymphatic system's volume and diffusivity were linked to amyloid beta deposition, neuronal damage, and cognitive impairment in patients with Alzheimer's.

SourceJuntendo University Research Promotion Center·JournalNeurology·TypeExperimental study·DateDec 6, 2022

USTC researchers develop highly hydrated paramagnetic amorphous calcium carbonate nanoclusters as an MRI contrast agent

Researchers at USTC developed a novel MRI contrast agent using highly hydrated paramagnetic amorphous calcium carbonate nanoclusters, exhibiting improved relaxivity and mass production. The material shows great potential in creating efficient diagnostic agents with low toxicity.

SourceUniversity of Science and Technology of China·JournalNature Communications·DateNov 29, 2022

Rice refines analysis of MRI contrast agents

A Rice-led team developed molecular simulations that reveal distinct differences in how inner and outer shells of water molecules around gadolinium respond to thermal excitation. Temperature affects the self-diffusivity of molecules, influencing relaxation rates in MRI scans.

SourceRice University·JournalPhysical Chemistry Chemical Physics·TypeComputational simulation/modeling·DateNov 17, 2022