Research on how disease is diagnosed. Covers fetal-distress detection, faster diagnostics, redefining conditions, and bias in medical AI.
A study of 3,028 patients with COVID-19 reveals that race, ethnicity, and severity of infection are key factors contributing to delayed cancer treatment. Researchers found that these patient demographic factors are strongly associated with delays in receiving timely medical care.
A newly developed polarizer-embedded metalens microscope system achieves high-quality, wide-field imaging with a large depth-of-field, significantly expanding human eyesight to the microworld. The chip-scale device offers a thousand-fold reduction in volume and weight compared to traditional microscopes.
A new study by the University of Exeter recommends using metaphors, images, and poetry to complement traditional medical scales for patients to describe their chronic pain. This approach can improve doctor-patient communication and aid diagnosis or provide better support.
A new visualization tool combines clinical and home blood pressure readings to aid in blood pressure management. It enhances shared decision-making between doctors and patients by integrating at-home readings with electronic health records.
Researchers say stereotypes and stigma surrounding mental illness can lead to poor workplace behavior. Employees with mental illnesses may face fear of discrimination, which drives inauthenticity and counterproductive work behaviors.
A pooled data analysis of 11 international studies found that NAFLD is associated with a 50% heightened risk of developing heart failure. The severity of NAFLD also increases the risk, especially with extensive liver fibrosis.
A study published in Pediatrics found that there is no consistent medical definition of growing pains, with over 93% of studies not referencing growth or age. The condition's vague and contradictory definitions raise questions about its connection to growth and cause.
Researchers developed a nanomembrane system called iTEARS that can quickly analyze tears for disease biomarkers. The system enables more efficient and less invasive molecular diagnoses for various diseases, including dry eye disease and diabetic retinopathy.
A recent study published in The Lancet Global Health reveals stark differences in survival rates for children with retinoblastoma between high- and low-income countries. In low-income countries, the risk of death from retinoblastoma within three years of diagnosis is significantly higher, with over two-fifths of children dying within t...
A study published in CMAJ found that patients who received care from physicians speaking their primary language had shorter hospital stays and fewer falls and infections. Francophones had a 24% lower risk of death, while allophones had a 54% lower risk.
Researchers from Tianjin Medical University General Hospital review sarcopenic obesity's impact on liver disease, including nonalcoholic fatty liver disease and cirrhosis. The study aims to clarify the pathogenesis of sarcopenic obesity and identify potential therapeutic avenues.
A new study by University of Cambridge researchers found that male dogs are four to five times more likely than female dogs to be infected with the oro-nasal form of Canine Transmissible Venereal Tumour. This unusual cancer is infectious and can spread between dogs through contact, commonly affecting genitals but also the nose and mouth.
The World Health Organization's International Classification of Diseases has introduced a new diagnosis for complex post-traumatic stress disorder (CPTSD), expanding the criteria for PTSD. CPTSD is characterized by excessive emotional responses, feelings of worthlessness, and difficulties in relationships.
The International Osteoporosis Foundation proposes a screening strategy to identify women at high risk of hip fracture, which could lead to a reduction in treatment gaps and improved identification of fractures. The approach combines low-cost assessment with targeted intervention using low-cost generic treatments.
The MedSENS instrument measures body temperature, heart rate, and oxygen saturation from the ear canal using innovative sensors. It has been tested in harsh environments and proven to be easy to use, with its data transmitted wirelessly to other devices.
Researchers have developed an app to help doctors identify patients with chronic lymphocytic leukemia (CLL) at risk of developing infections, allowing for earlier treatment. The app uses blood test results and genetic data to predict patient risk, improving treatment outcomes and reducing pressure on the healthcare system.
A study published in JMIR Formative Research reveals that automated analysis of a common clinical drawing task can be used to estimate cognition in older adults from Japan and the USA. Researchers found that people with lower cognitive scores had more variability in their drawing speed, angle, and time spent paused during the task.
Researchers have developed a novel fusion protein that enables the detection of SARS-CoV-2 antibodies using widely available glucose meters. The test was validated on various patient samples and found to be as accurate as four different ELISAs.
Researchers analyzed data from 599 patients with premenstrual dysphoric disorder and found that 34% have attempted suicide, with high rates of suicidal ideation, planning, and self-injury among women. The study highlights the need for accurate diagnosis and screening of suicidal ideation in patients with PMDD.
Researchers evaluate Jumpcode Genomics CRISPRclean technology for transforming pandemic response through highly sensitive testing. The assay quickly identifies variant strain types and individual host responses in a single workflow.
A recent OSU study found people with rare diseases often wait years for diagnosis, experience anxiety, depression and stigma due to inaccessible care. Education of medical professionals is crucial to address these challenges.
The SHIELD program employed rapid saliva testing, real-time data analysis, and fast reporting to mitigate the spread of COVID-19. The program's success led to a significant reduction in cases and deaths on campus, with Champaign County experiencing a third less COVID-19 cases than expected.
Women with polycystic ovary syndrome (PCOS) are at a higher risk of developing additional medical conditions such as migraine, hypertension, and endometriosis. They also report poorer health and use medications more frequently than women without PCOS.
A recent Oregon State University study found that COVID-19 patients had a 25% increased risk of developing a psychiatric disorder in the four months following their infection. The study matched 46,610 COVID-19 positive individuals with control patients and found a significant increase in anxiety disorders but no change in mood disorders.
Physicians recognize benzodiazepine dependence as a significant contributor to the opioid crisis, coined a new term CPBD. Long-term treatment can lead to severe withdrawal symptoms and recurrence of underlying anxiety and insomnia.
Patients with primary glomerular diseases have a significantly higher risk of cardiovascular events, including coronary artery disease and stroke. The study found that inclusion of kidney-specific risk factors improved the prediction of cardiovascular events.
Researchers at Kobe University and Hiroshima University have developed a biomarker that can diagnose Parkinson's disease from blood serum samples. The 'P450 inhibition assay' uses 12 different human P450s to detect changes in metabolites, allowing for accurate diagnosis with an accuracy rate of 85-88%. This breakthrough could lead to f...
Veterinarians at UC Davis have developed an AI model that can predict Leptospirosis in dogs with high accuracy, outperforming traditional testing methods. The model uses machine-learning algorithms to analyze historical data and provide timely predictions, which can be an online resource for veterinarians.
A new smartphone app using AI technology has been found to be as accurate as expert gastroenterologists in characterizing stool specimens. The app's ability to provide detailed descriptions of constipation, diarrhea, and normal stools surpasses that of patient reports.
A new study found significant genetic differences in type 2 diabetes risk compared to European populations. Combining a genetic risk score with a clinical risk score improved the prediction of type 2 diabetes in British Pakistani and British Bangladeshi individuals, especially in young people.
Researchers developed efficient metal-free polymeric scintillators for high-resolution X-ray imaging, outperforming conventional anthracene-based scintillators. The polymers exhibit multicolor radioluminescence and high photostability, enabling applications in radiation detection, medical diagnosis, and security inspection.
A significant proportion of patients with head and neck squamous cell carcinoma who smoke daily at diagnosis continue to smoke two years post-treatment. Most quitters stop smoking within the first six months after treatment.
A new study from Tel Aviv University finds that women aged 55 and over who snore are at significant risk for sleep apnea, which can be fatal. The researchers warn that the phenomenon often occurs during sleep, causing women to be unaware of their condition.
Researchers developed a new test method to detect tuberculosis (TB) progression from latent infection in elephants using IgG antibodies against Antigen 85B. High levels of IgG against ESAT6/CFP10 remained constant, while IgG against Ag85B increased before disease onset and declined with treatment.
A team of international researchers created digital models of disease interactions to identify key proteins and signaling cascades in seasonal allergies. They found that inhibiting PDGF-BB protein was more effective than existing treatments, suggesting a potential breakthrough in personalized medicine.
A comprehensive tool to assess Long COVID symptoms has been developed at the University of Birmingham. The Symptom Burden Questionnaire captures a wide range of symptoms affecting everyday life, providing valuable evidence for researchers and policymakers.
A Swedish study found that children with migration backgrounds are less likely to receive recommended psychiatric diagnoses and treatments for conditions like ADHD and depression. They were 40% less likely to receive certain diagnoses and 30% less likely to receive psychotherapy or ADHD drugs.
The UK National Osteoporosis Guideline Group has published a new guideline for the prevention and treatment of osteoporosis, which includes updated recommendations for vertebral fracture detection and anabolic treatment options. The guidance aims to improve service provision in both primary and secondary care settings.
A study by Osaka University researchers reveals patients waited years for diagnosis of rare diseases like hereditary angioedema. Long diagnostic delays can be fatal, and raising awareness is key to improving treatment.
Researchers at Tokyo University of Science discovered that disulfiram inhibits FROUNT protein and chemokine signaling pathways, reducing anxiety levels in mice. The study suggests a potential breakthrough anti-anxiety medication with safe and effective treatment for elderly patients suffering from anxiety and insomnia.
A recent study published in JAMA Ophthalmology analyzed the incidence of vision loss caused by retinal vein or artery blockage in 430,000 patients after a COVID-19 infection diagnosis. The research suggests that COVID-19 may be associated with an increased risk of this condition.
Researchers at Rutgers University found disparities in palliative care and hospice referrals among minority patient groups, highlighting the need for standardized policies to improve access. The studies revealed that language barriers, economic status, and cultural differences contribute to these gaps in care.
New research reveals that women with strokes often exhibit generalized symptoms such as confusion and weakness, potentially leading to delayed diagnoses. Women also face worse post-stroke outcomes, including increased institutionalization rates, compared to men.
A new study found that older children (6–12 years, 13–17 years) and those with high inflammation markers were at highest risk of severe MIS-C. Gastrointestinal symptoms and cardiac involvement were common in affected children.
A new study found that some symptoms commonly used to diagnose concussions, such as fatigue and neck pain, can be caused by intense exercise rather than a brain injury. The research highlights the need to consider these factors when assessing concussion in athletes on the field.
A new approach for measuring physician adherence to best practices has been developed, taking into consideration patient characteristics and physician training background. The study found that pulmonary and critical care medicine training was associated with higher recognition of ARDS, a form of lung failure.
Researchers found that AI-enhanced diagnosis helps doctors accurately detect fetal congenital heart disease, with fellows making the most accurate diagnoses. The new system uses graphical charts to represent the AI's analysis of ultrasound videos, improving accuracy and trust among medical professionals.
Researchers identified ephrin ligands in saliva samples of patients hospitalized with COVID-19, strongly associated with severe diagnosis. Saliva analysis could provide a simple, non-invasive method to detect infections and guide care.
Researchers have discovered a significant association between acute kidney injury and an increased risk of developing dementia in patients hospitalized with AKI. Early detection and monitoring may lead to improved outcomes for this high-risk population.
Researchers have discovered 23 proteins in breast milk that could indicate breast cancer, paving the way for a potential blood test. The study's findings, if confirmed, may enable earlier diagnosis and improve survival rates.
A new study reveals that nearly half of all older adults now die with a dementia diagnosis listed on their medical record, a 36% increase from two decades ago. This rise may be attributed to better public awareness, more detailed medical records, and Medicare billing practices, rather than an actual increase in the condition.
A study of 3.5 million Medicare decedents found the percentage of dementia diagnoses at end-of-life increased from 35% in 2004 to 47% in 2017. This rise may be attributed to heightened awareness and changes in billing practices.
A new multimodal eye scanner combining optical coherence tomography (OCT) and Raman spectroscopy enables the detection of molecular information in the internal structure of the eye. This technology aims to detect neurodegenerative diseases, such as Alzheimer's and Parkinson's, at an early stage, improving treatment options.
Researchers developed a new framework to extract meaningful vectorial metrics from Mueller matrix elements, providing insights into exotic material characterization and precise cancer boundary detection. The framework establishes a universal metric for calculating different physical properties of target objects.
A new study found that women's health research is disproportionately focused on reproductive years, particularly pregnancy, leaving few articles on major causes of illness and death. Non-communicable diseases, such as cancer and cardiovascular disease, are poorly covered in women's health publications.
Research reveals stark inequalities in long-term health outcomes for Black and South Asian women with a history of gestational diabetes. The study found that these women are up to three times more likely to develop certain health conditions, including type 2 diabetes and cardiovascular disease.
A telephone survey called Telephone Interview for Cognitive Status (TICS) was found to be effective in detecting dementia in primary care patients. TICS scored well as a low-cost diagnostic tool, with a score of less than 30 indicating a positive screen for dementia.
Researchers have identified phosphorylated human telomerase reverse transcriptase (hTERT) as a novel biomarker for aggressive cancers with poor prognosis. Elevated levels of this modified enzyme are found in various types of cancer, particularly those with aggressive features.
Researchers have developed a robust and stretchable ECM hydrogel-based membrane with nanofiber scaffolds, mimicking native basement membranes. This membrane enables cyclic stretching motions and maintains stable structure over extended cell culture periods, contributing to fabricating sophisticated artificial organs.
Researchers have created a 'worm-on-a-chip' device that uses roundworms to detect lung cancer cells, showing 70% accuracy. The device could potentially help doctors diagnose cancer at an earlier stage non-invasively.