Research on how disease is diagnosed. Covers fetal-distress detection, faster diagnostics, redefining conditions, and bias in medical AI.
A study found that children born in November-December had an 80% higher risk of being prescribed ADHD medication compared to those born in January-February. The researcher suggests that the youngest children are being overmedicated due to their age, rather than any inherent difference in maturity.
Researchers found that a one-year increase in retinal age was associated with a 10% higher risk of incident kidney failure over 11 years. Retinal age gap, a non-invasive biomarker based on retinal imaging, may help identify people at elevated risk for kidney failure.
Researchers developed an efficient engineered pathogen capture method to quickly identify infectious microbes in tiny blood samples. This advanced technology could significantly improve clinical outcomes for children with bloodstream infections and sepsis.
A study from the University of Colorado Cancer Center highlights the need for more data on pregnancy and targeted therapy in women with oncogene-driven lung cancer. The authors share their experience with pregnancies and surrogacy, emphasizing the importance of informed decision-making.
A recent study by Rutgers University researchers found that adolescent girls typically engage in unnoticed dieting for up to six months before their formal diagnosis of anorexia is made. This behavior often begins around age 14 and can be a precursor to more severe restrictive eating habits.
Researchers have discovered a way to predict the course of ALS by measuring immune cells in cerebrospinal fluid. A high proportion of effector T cells is associated with low survival rates, while activated regulatory T cells indicate a protective role against rapid disease progression.
UVA researchers developed a new tool to analyze genetic data, reducing noise and bias in cancer diagnosis. The tool uses mathematical modeling to identify patterns in chromatin, helping scientists detect tiny numbers of disease cells.
Population-based cancer screening rates declined during the pandemic, only to recover rapidly in initial stages; however, long-term follow-up reveals ongoing gaps in preventive care. The study suggests that prolonged disruptions in screening can have lasting effects on public health.
Researchers at the University of Ottawa have discovered that patients with electrolyte abnormalities are twice as likely to be diagnosed with an eating disorder. This study analyzed Ontario health data between 2008 and 2020, identifying a potential preventative treatment for approximately 1 million Canadians.
A large South Korean cohort study found a five-fold increased risk of chronic kidney disease (CKD) for adults with persistent hematuria. Associations were stronger in men compared to women.
A recent study by Washington State University found that rural public schools are less likely to provide mental health services compared to urban schools, with only 38.3% offering treatment. Rural schools also reported lower funding and lack of access to qualified professionals as barriers to providing these services.
A study of 11,945 people found that those with type 2 diabetes are more likely to be diagnosed with advanced cancer if the condition is not screened for routinely. Researchers identified a 26% increased risk of metastasis in patients with pre-existing type 2 diabetes.
A study found that ER visits for suicidal thoughts among youth aged 5-19 increased by 59% from 2016-2017 to 2019-2021, with hospitalizations rising by 57%. The research highlights the need for improved mental wellness support and training for healthcare providers.
A new study found that vulnerable populations, including children, older individuals, and men, faced significant challenges in accessing TB diagnoses due to COVID-19 disruptions. The research emphasizes the need for targeted interventions to address these inequalities and ensure equitable access to TB care.
A new study published in PLOS Medicine found significant long-term morbidity in children, adolescents, and adults after COVID-19 infection. Children and adolescents are at risk of post-COVID-19 syndrome, with rates of malaise, cough, and headache increased compared to controls.
A new study identifies sexual activity as a potential trigger for asthma exacerbations, which can be managed with the guidance of an allergist. The authors suggest that discussing sex with an allergist can help patients avoid triggering flares and improve their quality of life.
Researchers found a strong association between outpatient electrolyte abnormalities and subsequent eating disorder diagnoses, suggesting these abnormalities may serve as a screening tool. The median time from the earliest abnormality to diagnosis exceeded one year.
A global study found a significant increase in diabetic ketoacidosis cases among children diagnosed with type 1 diabetes during the COVID-19 pandemic. The observed prevalence was significantly higher than predicted, highlighting the need for better public awareness and screening programs.
A higher urine-to-plasma urea ratio is associated with faster decline in eGFR and development of kidney failure in patients with common forms of CKD. This biomarker may improve risk prediction, particularly in low-cost, easily measurable assays.
Researchers developed a fast and cost-effective method to detect amphiphiles, a ubiquitous family of chemical compounds used in disease diagnosis and toxin detection. The new test uses rolling droplets on microstructured surfaces to detect levels of pathogenic endotoxins in water at ultralow concentrations.
A study published in Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring found that analyzing patients' speech can distinguish between different types of dementia. The research team developed a machine learning model using speech features to identify Alzheimer's disease and Lewy body dementia.
A study published in the Journal of Alzheimer's Disease found that analyzing patients' drawing tests can help diagnose Alzheimer's disease (AD) and distinguish it from dementia with Lewy bodies (DLB). The researchers discovered that DLB patients showed differences in speed-, pressure-, and pause-related features, whereas AD patients sh...
A study analyzing health records of veterans with SARS-CoV-2 infection and long COVID symptoms reveals the challenges of diagnosing and managing this condition. The analysis highlights complexities in clinical diagnosis and patient care.
Researchers found that structural racism and insurance barriers limit access to advanced epilepsy care for minority groups in New Jersey. Black patients with private insurance and Medicaid had the lowest EMU admission rates relative to emergency room visits.
Researchers found that reducing SAMHD1 levels made brain tumor cells sensitive to chemotherapy drugs and slowed cell growth. They also suspect that glioblastoma alters SAMHD1's function to aid its own survival and treatment resistance.
Research found a hospital code response team arrives at least one minute quicker and leads to better patient outcomes with smartphone emergency code notification systems. The study used a secure texting system that connected with electronic medical records, reducing conventional methods' average delay of 78 seconds.
Research from UCLA Health Sciences found that telehealth consultations following an emergency department visit were associated with 28 more repeat ED encounters and nearly 11 more return hospital admissions per 1000 patients. The findings highlight the need for careful consideration of when to use telemedicine for post-ED follow-ups.
A meta-analysis of 410 articles from 68 countries found that patients in lower-income countries take up to four times longer to initiate care for cancer treatment. Cancers causing non-specific symptoms, such as myeloma and colorectal cancer, typically take the longest to diagnose.
Researchers suggest new criteria for diagnosing sarcopenia, a syndrome characterized by loss of muscle mass and force, with lower cutoff points leading to improved prediction of mortality risk. The study found that raising handgrip strength thresholds can detect the onset of sarcopenia earlier and more accurately.
A study found that in people with significant kidney disease, psoriasis does not increase the risk of heart attack. After controlling for other risk factors, researchers found no association between psoriasis and heart attacks in patients with end-stage renal disease.
A new study by UCL researchers found that talking therapies on the NHS can improve the mental health of people with dementia, with 63% experiencing a reduction in symptoms. The therapy proved clinically beneficial, even though response rates were lower than those without dementia.
A recent study analyzed the records of over 33,000 dementia patients in Wales and found that those closest to their diagnosis were taking an average of three or more medications. This suggests a possible link between polypharmacy and the development of dementia.
Researchers from Rutgers Cancer Institute have identified specific microorganisms associated with inflammation and poor survival in pancreatic tumors. These microbial signatures can be used as new targets for earlier diagnosis or treatment of the fourth leading cause of cancer death.
A nationally representative study of 594,000 persons in England found an increased risk of suicide associated with dementia diagnosis before age 65. The study identified younger patients diagnosed within the 3-month post-diagnostic period as high-risk groups for suicidal thoughts and behaviors.
A national US kidney disease registry found that 60% of participants were unaware of their kidney function level, hindering clinical trial recruitment. The National Kidney Foundation Patient Network aims to address this issue through real-world data collection and patient-centered research.
A Rutgers study found that racial and ethnic minorities with dementia receive more intensive end-of-life care. This disparity may be attributed to systemic racism, discrimination, or poor physician communication. The researchers suggest improving end-of-life care and outcomes for people with dementia through initiatives like advance ca...
Anemia is common among adults with advanced kidney disease, associated with adverse outcomes and low eGFR levels. Effective iron supplementation is a low-risk intervention to address this issue, emphasizing the need for increased testing and treatment.
Researchers developed a novel three-core optical fiber sensor to accurately measure both the magnitude and direction of spine curvature. The sensor offers advantages like low cost, high sensitivity, and small size, making it a promising tool for doctors to diagnose problems in spine curvature.
Reduced kidney function and increased urine albumin excretion are associated with brain volume reduction in regions typically affected by Alzheimer's disease and other dementia etiologies. Cognitive decline is common in patients with kidney disease, and this study provides new insights into the etiology and localization of brain damage.
A public consultation is launched to develop best-practice standards for diverse and inclusive healthcare datasets used in Artificial Intelligence. The project aims to reduce biases that affect patients from minoritised racial/ethnic groups, ensuring they receive accurate predictions and treatments.
Researchers developed DNA nets to detect and impede COVID-19, offering a fast, sensitive, and low-cost testing platform. The technique also showed potential as an antiviral treatment, inhibiting the virus's spread in live cell cultures.
A new study reveals that smoking is the main cause of preventable cancer and death in England, with socio-economic disparities in cancer incidence attributed to smoking prevalence. If everyone had the same smoking prevalence as the least deprived quintile, over 5,000 cases per year could have been prevented.
Scientists have developed a face mask that can detect common respiratory viruses in the air, alerting wearers via mobile devices within 10 minutes. The mask uses aptamers to identify unique proteins on viral surface proteins, amplifying signals to detect even trace levels of pathogens.
The study found a significant decline in peritoneal dialysis-associated peritonitis rates over time, with consistent differences in risk by race and age. The decline suggests improvements in clinical practice and highlights the importance of uniform coding standards to identify additional risk factors.
A team of researchers has designed in silico molecular probes to track the progress of a misbehaving protein linked to neurodegenerative diseases like ALS and FTD. The probes can detect TDP-43 aggregates at high resolution, paving the way for early diagnosis.
A recent study has found that vitamin D deficiency is associated with lower overall survival rates in melanoma patients. The research, presented at the European Academy of Dermatology and Venereology Congress, suggests that vitamin D levels play a significant role in determining patient outcomes.
A study by NTU Singapore found that people have lower trust in health interventions suggested by AI alone, compared to those they perceive as based on human expert opinion. Emphasizing the involvement of a human health expert can improve acceptance and effectiveness of AI-suggested preventive care measures.
A study of nearly 2,400 patients found that video telemedicine consultations matched in-person diagnoses in 87% of cases. The findings suggest a high degree of diagnostic accuracy for video telemedicine visits for most new clinical concerns.
Scientists at the University of Freiburg have successfully characterized epigenetic modifications using nanopore analysis. The technique allows for rapid detection of protein fragments with varying levels of acetylation, enabling more accurate diagnosis and treatment of diseases like cancer.
Researchers use human tissue models to study myocardial infarction, a leading cause of mortality worldwide. These models allow for early detection of discrepancies between animal and human responses, enabling faster and safer clinical trials.
Researchers developed a method to identify valve dysfunction using complex network analysis that is accurate, simple to use, and low-cost. The diagnostic tool works by analyzing the sounds produced by the heart, creating a graph of connected points, and identifying correlations between nodes.
A long-term study found that older homeless people are at a high risk of dying, with a median age of death of 64.6 years old. The study also found that people who first became homeless at age 50 or later were about 60 percent more likely to die than those who had become homeless earlier in life.
A large study of over 296,000 patients found that being overweight was negatively associated with dementia in women, while underweight was positively linked to an increased risk of dementia in men. The results suggest that moderate weight gain may be beneficial for cognitive health in older women.
A new study published in JCPP Advances explores the impact of gender differences on autism diagnosis, finding that women's higher emotional needs may mask their autistic traits. The research highlights the importance of improving accurate diagnosis for both men and women, with potential implications for clinical practice.
Researchers have found that children with autism show significant differences in their pupillary light reflexes, which can be used as a potential screening biomarker. The study demonstrates the parameters of interest that matter for detecting autism and validates earlier findings using monocular technology.
A study of 350 older adults found that those with multiple chronic health conditions, especially women, are more prone to large blood pressure drops and lower brain oxygenation after standing up. This increases their risk of dizziness, faints, and falls, highlighting the importance of detecting and managing multi-morbidity.
Guidelines for diagnosing and managing Pollen Food Syndrome (PFS) have been developed to distinguish it from primary allergies and manage dietary restrictions. The guideline highlights the need for more research on health-related quality of life and novel treatments, including food immunotherapy.
A multi-institutional team assessed the diagnostic criteria for canine glioma using the Comparative Brain Tumor Consortium's guidelines. The study found that consensus was achieved for 71 out of 85 cases (84%), with a moderate level of inter-pathologist agreement.
The new guideline provides evidence-based recommendations for managing patients on warfarin, DOACs, and antiplatelet drugs before and after surgeries. It aims to minimize preventable bleeding and thrombotic events by standardizing approaches and protocols.
A recent study published in PLOS ONE found that opioid prescriptions declined for US patients with both cancer and non-cancer pain between 2012 and 2019. The proportion of people receiving any opioid prescription dropped from 49.7% to 30.5% for non-cancer pain and from 86.0% to 78.7% for cancer pain.